| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Brivudine perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Brivudine_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.182826 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.143973 |
| HDAC9 | histone deacetylase 9 | 0.101097 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0957085 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.08655 |
| RPL3 | ribosomal protein L3 | 0.0846828 |
| UBC | ubiquitin C | 0.0723878 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0715515 |
| PDGFC | platelet derived growth factor C | 0.0702715 |
| TJP1 | tight junction protein 1 | 0.0668739 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0661832 |
| ANXA1 | annexin A1 | 0.0661053 |
| ZNF608 | zinc finger protein 608 | 0.0660953 |
| MACROD2 | MACRO domain containing 2 | 0.0652448 |
| DIAPH3 | diaphanous-related formin 3 | 0.0646436 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0598626 |
| EZR | ezrin | 0.0588378 |
| CENPF | centromere protein F, 350/400kDa | 0.0533363 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.052566 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0508247 |
| CREB5 | cAMP responsive element binding protein 5 | 0.0504481 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.0496859 |
| POTEF | POTE ankyrin domain family, member F | 0.049665 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0489213 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0458564 |
| ANKRD36 | ankyrin repeat domain 36 | 0.045634 |
| ENO1 | enolase 1, (alpha) | 0.0451652 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.044982 |
| ANLN | anillin, actin binding protein | 0.0444734 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0444282 |
| RPS8 | ribosomal protein S8 | 0.0443116 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0436806 |
| MYOF | myoferlin | 0.0435674 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0432493 |
| USP47 | ubiquitin specific peptidase 47 | 0.0429634 |
| MKI67 | marker of proliferation Ki-67 | 0.0420906 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | 0.0412003 |
| JUN | jun proto-oncogene | 0.0399986 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0396849 |
| AHCYL2 | adenosylhomocysteinase-like 2 | 0.0390149 |
| SOX6 | SRY (sex determining region Y)-box 6 | 0.0389876 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0389698 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0385209 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0381805 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.037877 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0369467 |
| VCL | vinculin | 0.0368013 |
| ASPH | aspartate beta-hydroxylase | 0.0366976 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0365207 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0364712 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0362956 |
| EML4 | echinoderm microtubule associated protein like 4 | 0.0359156 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0354834 |
| RAB27B | RAB27B, member RAS oncogene family | 0.0348369 |
| BRD2 | bromodomain containing 2 | 0.0341293 |
| FNIP1 | folliculin interacting protein 1 | 0.0336785 |
| RPL14 | ribosomal protein L14 | 0.0333554 |
| SGMS2 | sphingomyelin synthase 2 | 0.0328323 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0316383 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0307845 |
| RPS12 | ribosomal protein S12 | 0.0303304 |
| AMOTL2 | angiomotin like 2 | 0.0297363 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0288948 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0281536 |
| GOLGB1 | golgin B1 | 0.0280124 |
| CCDC88A | coiled-coil domain containing 88A | 0.0278874 |
| NAV2 | neuron navigator 2 | 0.027713 |
| RPL4 | ribosomal protein L4 | 0.0276246 |
| RPS18 | ribosomal protein S18 | 0.0274442 |
| B2M | beta-2-microglobulin | 0.0271755 |
| TXNIP | thioredoxin interacting protein | 0.026956 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0264614 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.0264609 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0262634 |
| MCL1 | myeloid cell leukemia 1 | 0.026054 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0260495 |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) | 0.0259952 |
| DST | dystonin | 0.0259439 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0259036 |
| FGD4 | FYVE, RhoGEF and PH domain containing 4 | 0.0259013 |
| YAP1 | Yes-associated protein 1 | 0.0256735 |
| SIK3 | SIK family kinase 3 | 0.0254793 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0250469 |
| ECT2 | epithelial cell transforming 2 | 0.0248453 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0246706 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | 0.0244289 |
| CALR | calreticulin | 0.0244049 |
| LONRF2 | LON peptidase N-terminal domain and ring finger 2 | 0.024388 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.024377 |
| CD47 | CD47 molecule | 0.0243537 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0243114 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0242884 |
| FAT1 | FAT atypical cadherin 1 | 0.0241782 |
| TPX2 | TPX2, microtubule-associated | 0.0241639 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0241488 |
| HSPB1 | heat shock 27kDa protein 1 | 0.0241358 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 0.0240442 |
| KIF11 | kinesin family member 11 | 0.0239287 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.023627 |
| GALNT5 | polypeptide N-acetylgalactosaminyltransferase 5 | 0.0235892 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.165619 |
| PTMA | prothymosin, alpha | -0.146261 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.118625 |
| CACNB4 | calcium channel, voltage-dependent, beta 4 subunit | -0.092819 |
| TXNRD1 | thioredoxin reductase 1 | -0.0923257 |
| S100A6 | S100 calcium binding protein A6 | -0.0897787 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0884751 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0831757 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.0742664 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.071553 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.0705669 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0692147 |
| TNFRSF11B | tumor necrosis factor receptor superfamily, member 11b | -0.0645668 |
| RPL35A | ribosomal protein L35a | -0.0645463 |
| NBEA | neurobeachin | -0.0638155 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0628665 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0587223 |
| FLNB | filamin B, beta | -0.0567626 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0536458 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0520107 |
| ACTG1 | actin gamma 1 | -0.0517886 |
| S100A4 | S100 calcium binding protein A4 | -0.0516275 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0462014 |
| TMSB4X | thymosin beta 4, X-linked | -0.044182 |
| RPLP0 | ribosomal protein, large, P0 | -0.0431373 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0423333 |
| TMEM41B | transmembrane protein 41B | -0.0422532 |
| SMNDC1 | survival motor neuron domain containing 1 | -0.0408474 |
| ANK2 | ankyrin 2, neuronal | -0.0407921 |
| RPL11 | ribosomal protein L11 | -0.0391243 |
| CCND1 | cyclin D1 | -0.0386106 |
| GCNT1 | glucosaminyl (N-acetyl) transferase 1, core 2 | -0.0383045 |
| RBM39 | RNA binding motif protein 39 | -0.0376642 |
| PARD3 | par-3 family cell polarity regulator | -0.0375025 |
| PYGB | phosphorylase, glycogen; brain | -0.0373452 |
| ALDH3A2 | aldehyde dehydrogenase 3 family, member A2 | -0.0368241 |
| RHBDD1 | rhomboid domain containing 1 | -0.0364957 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0361904 |
| CAMKMT | calmodulin-lysine N-methyltransferase | -0.0361766 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.035854 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0349647 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0348461 |
| ADAM10 | ADAM metallopeptidase domain 10 | -0.0346608 |
| FOXP1 | forkhead box P1 | -0.0342292 |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 | -0.0339243 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0330493 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0316982 |
| CYB5B | cytochrome b5 type B (outer mitochondrial membrane) | -0.0314696 |
| NF1 | neurofibromin 1 | -0.0309889 |
| NFIA | nuclear factor I/A | -0.0308936 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0306589 |
| GNAS | GNAS complex locus | -0.0306304 |
| HDLBP | high density lipoprotein binding protein | -0.0304745 |
| ADNP | activity-dependent neuroprotector homeobox | -0.0301618 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0298534 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0295228 |
| AHI1 | Abelson helper integration site 1 | -0.0295019 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.0294298 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0283244 |
| RIGI | RNA sensor RIG-I | -0.0283021 |
| OSMR | oncostatin M receptor | -0.0270442 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0269245 |
| FKBP10 | FK506 binding protein 10, 65 kDa | -0.0268895 |
| AGPAT3 | 1-acylglycerol-3-phosphate O-acyltransferase 3 | -0.0268847 |
| SERPINB6 | serpin peptidase inhibitor, clade B (ovalbumin), member 6 | -0.0267377 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0263852 |
| LARP1 | La ribonucleoprotein domain family, member 1 | -0.0256195 |
| KLF3 | Kruppel-like factor 3 (basic) | -0.0254495 |
| RPS21 | ribosomal protein S21 | -0.0253965 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | -0.0251843 |
| NEBL | nebulette | -0.0250881 |
| EHBP1 | EH domain binding protein 1 | -0.0249607 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | -0.0249399 |
| FHAD1 | forkhead-associated (FHA) phosphopeptide binding domain 1 | -0.0247984 |
| USP3 | ubiquitin specific peptidase 3 | -0.0247575 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0247128 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0245914 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.02457 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -0.0244694 |
| PLXNA2 | plexin A2 | -0.024466 |
| ZRANB2 | zinc finger, RAN-binding domain containing 2 | -0.0243381 |
| GCLM | glutamate-cysteine ligase, modifier subunit | -0.0241854 |
| ZNF207 | zinc finger protein 207 | -0.0240574 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0240217 |
| RNF145 | ring finger protein 145 | -0.0238887 |
| WDR43 | WD repeat domain 43 | -0.0238715 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0238369 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0237401 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0235935 |
| PFN1 | profilin 1 | -0.0234659 |
| ACACA | acetyl-CoA carboxylase alpha | -0.0234125 |
| SPIDR | scaffolding protein involved in DNA repair | -0.0232646 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0231348 |
| RPS16 | ribosomal protein S16 | -0.0230791 |
| SEC63 | SEC63 homolog (S. cerevisiae) | -0.0229716 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | -0.0229134 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0228337 |
| PRDX2 | peroxiredoxin 2 | -0.0227673 |
| HMGB1 | high mobility group box 1 | -0.0227436 |
| RBM8A | RNA binding motif protein 8A | -0.0223625 |
