Bronchial Hyperreactivity Gene Set

Dataset CTD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description A chronic respiratory disease manifested as difficulty breathing due to the narrowing of bronchial passageways.|Tendency of the smooth muscle of the tracheobronchial tree to contract more intensely in response to a given stimulus than it does in the response seen in normal individuals. This condition is present in virtually all symptomatic patients with asthma. The most prominent manifestation of this smooth muscle contraction is a decrease in airway caliber that can be readily measured in the pulmonary function laboratory.|A form of bronchial disorder with three distinct components: airway hyper-responsiveness (RESPIRATORY HYPERSENSITIVITY), airway INFLAMMATION, and intermittent AIRWAY OBSTRUCTION. It is characterized by spasmodic contraction of airway smooth muscle, WHEEZING, and dyspnea (DYSPNEA, PAROXYSMAL).|A bronchial disease that is characterized by chronic inflammation and narrowing of the airways, which is caused by a combination of environmental and genetic factors resulting in recurring periods of wheezing (a whistling sound while breathing), chest tightness, shortness of breath, mucus production and coughing. The symptoms appear due to a variety of triggers such as allergens, irritants, respiratory infections, weather changes, excercise, stress, reflux disease, medications, foods and emotional anxiety. (Experimental Factor Ontology, EFO_0000270)
External Link http://ctdbase.org/detail.go?type=disease&acc=MESH:D016535
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Genes

570 genes/proteins associated with the disease Bronchial Hyperreactivity from the curated CTD Gene-Disease Associations dataset.

Symbol Name Standardized Value
ICAM1 intercellular adhesion molecule 1 2.88009
NGF nerve growth factor (beta polypeptide) 2.88009
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 2.88009
TRPA1 transient receptor potential cation channel, subfamily A, member 1 2.88009
SPON2 spondin 2, extracellular matrix protein 2.88009
CALCA calcitonin-related polypeptide alpha 2.88009
CCL2 chemokine (C-C motif) ligand 2 2.88009
VIP vasoactive intestinal peptide 2.88009
TAC1 tachykinin, precursor 1 2.88009
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) 2.88009
IL13 interleukin 13 2.88009
ADAM33 ADAM metallopeptidase domain 33 2.88009
IL1RN interleukin 1 receptor antagonist 2.88009
IL4 interleukin 4 2.40646
IL1B interleukin 1, beta 2.337
TNF tumor necrosis factor 2.30039
IL6 interleukin 6 2.23322
IFNG interferon, gamma 2.15497
CCL11 chemokine (C-C motif) ligand 11 2.14954
CXCL8 chemokine (C-X-C motif) ligand 8 2.12912
IL5 interleukin 5 2.12599
IL10 interleukin 10 2.11541
MUC5AC mucin 5AC, oligomeric mucus/gel-forming 2.10819
MMP9 matrix metallopeptidase 9 2.08645
CCL3 chemokine (C-C motif) ligand 3 2.02361
MAPK3 mitogen-activated protein kinase 3 1.99495
MAPK1 mitogen-activated protein kinase 1 1.98668
IL12B interleukin 12B 1.94469
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 1.94374
CXCL10 chemokine (C-X-C motif) ligand 10 1.8991
MGST1 microsomal glutathione S-transferase 1 1.88025
NOS2 nitric oxide synthase 2, inducible 1.86097
ALB albumin 1.85098
SELP selectin P (granule membrane protein 140kDa, antigen CD62) 1.83663
EGFR epidermal growth factor receptor 1.80529
EDN1 endothelin 1 1.75738
MPO myeloperoxidase 1.75182
HMOX1 heme oxygenase 1 1.7446
FOS FBJ murine osteosarcoma viral oncogene homolog 1.7424
VEGFA vascular endothelial growth factor A 1.73434
BAX BCL2-associated X protein 1.73008
NOS3 nitric oxide synthase 3 (endothelial cell) 1.728
CYSLTR1 cysteinyl leukotriene receptor 1 1.72738
RHOA ras homolog family member A 1.7226
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 1.69082
TGFB1 transforming growth factor, beta 1 1.69017
CCL5 chemokine (C-C motif) ligand 5 1.68718
IL2 interleukin 2 1.68148
CASP3 caspase 3, apoptosis-related cysteine peptidase 1.67333
ODC1 ornithine decarboxylase 1 1.6662
CAV1 caveolin 1, caveolae protein, 22kDa 1.66533
CD22 CD22 molecule 1.65336
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide 1.6473
MMP2 matrix metallopeptidase 2 1.64416
COL1A1 collagen, type I, alpha 1 1.63294
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) 1.63094
VCAM1 vascular cell adhesion molecule 1 1.63094
ADRB2 adrenoceptor beta 2, surface 1.62825
PCNA proliferating cell nuclear antigen 1.61178
CCL17 chemokine (C-C motif) ligand 17 1.61014
CAT catalase 1.59451
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 1.59241
GSTP1 glutathione S-transferase pi 1 1.58398
SFTPD surfactant protein D 1.58279
TFRC transferrin receptor 1.58089
CXCL2 chemokine (C-X-C motif) ligand 2 1.57688
TIMP1 TIMP metallopeptidase inhibitor 1 1.57378
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) 1.56923
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein 1.56582
CD44 CD44 molecule (Indian blood group) 1.55896
HSPA1A heat shock 70kDa protein 1A 1.55772
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 1.53086
CCL20 chemokine (C-C motif) ligand 20 1.52865
GSTM1 glutathione S-transferase mu 1 1.52616
IGFBP3 insulin-like growth factor binding protein 3 1.52464
CCL4 chemokine (C-C motif) ligand 4 1.52187
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 1.52036
PECAM1 platelet/endothelial cell adhesion molecule 1 1.51759
FAS Fas cell surface death receptor 1.50801
IL33R interleukin 33 receptor 1.50373
SOD1 superoxide dismutase 1, soluble 1.50298
IL2RB interleukin 2 receptor, beta 1.5012
PER2 period circadian clock 2 1.49584
IL18 interleukin 18 1.49174
CCND3 cyclin D3 1.48993
PTPRCAP protein tyrosine phosphatase, receptor type, C-associated protein 1.48608
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 1.48376
EPX eosinophil peroxidase 1.48299
DDIT3 DNA-damage-inducible transcript 3 1.47991
AREG amphiregulin 1.47219
SGK1 serum/glucocorticoid regulated kinase 1 1.47038
S100A4 S100 calcium binding protein A4 1.46807
PLAUR plasminogen activator, urokinase receptor 1.46356
C3 complement component 3 1.45168
TBX21 T-box 21 1.44626
CCNE1 cyclin E1 1.44273
FOSL1 FOS-like antigen 1 1.44001
INHBA inhibin, beta A 1.43974
NRN1 neuritin 1 1.4351
CCNA2 cyclin A2 1.43293
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon 1.4313
DBP D site of albumin promoter (albumin D-box) binding protein 1.4313
CASP1 caspase 1, apoptosis-related cysteine peptidase 1.43048
MS4A1 membrane-spanning 4-domains, subfamily A, member 1 1.42859
F7 coagulation factor VII (serum prothrombin conversion accelerator) 1.42156
APP amyloid beta (A4) precursor protein 1.42101
CCL7 chemokine (C-C motif) ligand 7 1.41992
ADRBK2 adrenergic, beta, receptor kinase 2 1.41911
NR4A1 nuclear receptor subfamily 4, group A, member 1 1.41829
MAPK14 mitogen-activated protein kinase 14 1.41559
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 1.40925
IL1A interleukin 1, alpha 1.40595
JUN jun proto-oncogene 1.40176
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3 1.40036
S100A8 S100 calcium binding protein A8 1.39757
PRKCB protein kinase C, beta 1.39757
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) 1.3973
ADM adrenomedullin 1.38946
TLR2 toll-like receptor 2 1.38185
FABP1 fatty acid binding protein 1, liver 1.38185
LEP leptin 1.37705
CH25H cholesterol 25-hydroxylase 1.37648
APOE apolipoprotein E 1.37648
IL17A interleukin 17A 1.37189
CLU clusterin 1.37103
FGF2 fibroblast growth factor 2 (basic) 1.36961
NFIL3 nuclear factor, interleukin 3 regulated 1.36933
VDAC1 voltage-dependent anion channel 1 1.3639
NCF2 neutrophil cytosolic factor 2 1.3639
CEBPB CCAAT/enhancer binding protein (C/EBP), beta 1.36304
HSPA1B heat shock 70kDa protein 1B 1.36161
LTF lactotransferrin 1.36133
MCM5 minichromosome maintenance complex component 5 1.35618
CXCL9 chemokine (C-X-C motif) ligand 9 1.35618
SIRPA signal-regulatory protein alpha 1.35531
ADIPOQ adiponectin, C1Q and collagen domain containing 1.35502
SELE selectin E 1.35444
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1 1.35357
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.35299
DUSP1 dual specificity phosphatase 1 1.35242
CKMT2 creatine kinase, mitochondrial 2 (sarcomeric) 1.35242
GSR glutathione reductase 1.34897
PPARG peroxisome proliferator-activated receptor gamma 1.34782
CAMK4 calcium/calmodulin-dependent protein kinase IV 1.34752
CASP9 caspase 9, apoptosis-related cysteine peptidase 1.34518
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 1.34372
HSF1 heat shock transcription factor 1 1.34372
PRMT1 protein arginine methyltransferase 1 1.34343
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 1.34227
HSPB1 heat shock 27kDa protein 1 1.34111
CTSB cathepsin B 1.34053
CCL22 chemokine (C-C motif) ligand 22 1.33966
RNASE3 ribonuclease, RNase A family, 3 1.33228
CD14 CD14 molecule 1.33052
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B 1.32905
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 1.32667
LRIG3 leucine-rich repeats and immunoglobulin-like domains 3 1.32488
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD) 1.31985
PTPRC protein tyrosine phosphatase, receptor type, C 1.31746
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 1.31746
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 1.31506
EEF2 eukaryotic translation elongation factor 2 1.31506
CKS1B CDC28 protein kinase regulatory subunit 1B 1.31387
MYC v-myc avian myelocytomatosis viral oncogene homolog 1.31237
GCLC glutamate-cysteine ligase, catalytic subunit 1.31237
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 1.31148
ARNTL aryl hydrocarbon receptor nuclear translocator-like 1.3103
CD47 CD47 molecule 1.30696
CASP4 caspase 4, apoptosis-related cysteine peptidase 1.30604
EGR1 early growth response 1 1.30604
FN1 fibronectin 1 1.30512
F2 coagulation factor II (thrombin) 1.30482
SLC22A8 solute carrier family 22 (organic anion transporter), member 8 1.3039
AQP3 aquaporin 3 (Gill blood group) 1.3039
CCND1 cyclin D1 1.30147
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 1.30117
NOS1 nitric oxide synthase 1 (neuronal) 1.30026
APOD apolipoprotein D 1.29996
ALOX5 arachidonate 5-lipoxygenase 1.29719
SOD2 superoxide dismutase 2, mitochondrial 1.29626
IRF1 interferon regulatory factor 1 1.29287
LOX lysyl oxidase 1.29072
CSF2RA colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) 1.28858
POLR1B polymerase (RNA) I polypeptide B, 128kDa 1.28858
LDLR low density lipoprotein receptor 1.28672
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 1.28456
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 1.2821
PLA2G2C phospholipase A2, group IIC 1.28088
GSTT1 glutathione S-transferase theta 1 1.27936
GALK1 galactokinase 1 1.27782
BCL2 B-cell CLL/lymphoma 2 1.2772
SYP synaptophysin 1.2772
MAP2K1 mitogen-activated protein kinase kinase 1 1.27347
STXBP1 syntaxin binding protein 1 1.27255
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 1.27193
ALOX5AP arachidonate 5-lipoxygenase-activating protein 1.27101
KIF23 kinesin family member 23 1.26794
ISG15 ISG15 ubiquitin-like modifier 1.26794
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2 1.26452
ANXA2 annexin A2 1.26236
CYP11A1 cytochrome P450, family 11, subfamily A, polypeptide 1 1.26236
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 1.26205
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 1.26113
ADRB1 adrenoceptor beta 1 1.26052
MUC16 mucin 16, cell surface associated 1.2596
CPNE5 copine V 1.25929
CYBB cytochrome b-245, beta polypeptide 1.25868
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4 1.25713
PYCARD PYD and CARD domain containing 1.25619
STAT1 signal transducer and activator of transcription 1, 91kDa 1.25432
BIRC5 baculoviral IAP repeat containing 5 1.25276
CHIA chitinase, acidic 1.24966
LY86 lymphocyte antigen 86 1.2475
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 1.24623
UCP1 uncoupling protein 1 (mitochondrial, proton carrier) 1.24496
BDKRB2 bradykinin receptor B2 1.24496
GADD45A growth arrest and DNA-damage-inducible, alpha 1.2437
BLNK B-cell linker 1.24275
VEGFC vascular endothelial growth factor C 1.24244
ANXA1 annexin A1 1.24181
EDNRB endothelin receptor type B 1.23456
GPX3 glutathione peroxidase 3 1.23456
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) 1.23392
NR1D1 nuclear receptor subfamily 1, group D, member 1 1.23137
BAK1 BCL2-antagonist/killer 1 1.23106
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) 1.22948
CD4 CD4 molecule 1.22948
ALPL alkaline phosphatase, liver/bone/kidney 1.22758
PHGDH phosphoglycerate dehydrogenase 1.22632
CYP2F1 cytochrome P450, family 2, subfamily F, polypeptide 1 1.22501
PPIB peptidylprolyl isomerase B (cyclophilin B) 1.22501
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase 1.22501
CCL19 chemokine (C-C motif) ligand 19 1.22469
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 1.22306
FILIP1 filamin A interacting protein 1 1.22242
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 1.22209
PTP4A1 protein tyrosine phosphatase type IVA, member 1 1.2208
CXCR4 chemokine (C-X-C motif) receptor 4 1.21887
NR3C2 nuclear receptor subfamily 3, group C, member 2 1.21823
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1 1.21823
PLA1A phospholipase A1 member A 1.21631
DUSP2 dual specificity phosphatase 2 1.21631
CYSLTR2 cysteinyl leukotriene receptor 2 1.21567
ATP5B ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide 1.21567
IL12A interleukin 12A 1.21567
HGF hepatocyte growth factor (hepapoietin A; scatter factor) 1.21206
LCN2 lipocalin 2 1.21206
MGLL monoglyceride lipase 1.21076
VLDLR very low density lipoprotein receptor 1.20816
H19 H19, imprinted maternally expressed transcript (non-protein coding) 1.20784
BCL2L1 BCL2-like 1 1.20654
FCER2 Fc fragment of IgE, low affinity II, receptor for (CD23) 1.20622
CXCL5 chemokine (C-X-C motif) ligand 5 1.2059
SPON1 spondin 1, extracellular matrix protein 1.20394
AGPAT9 1-acylglycerol-3-phosphate O-acyltransferase 9 1.20361
SCARB1 scavenger receptor class B, member 1 1.20196
TF transferrin 1.20196
IGFBP2 insulin-like growth factor binding protein 2, 36kDa 1.20097
PTAFR platelet-activating factor receptor 1.19999
PSMD12 proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 1.19966
PRUNE2 prune homolog 2 (Drosophila) 1.19802
SYT2 synaptotagmin II 1.19802
ACE angiotensin I converting enzyme 1.19704
CCT2 chaperonin containing TCP1, subunit 2 (beta) 1.19574
GCLM glutamate-cysteine ligase, modifier subunit 1.19509
CYP2S1 cytochrome P450, family 2, subfamily S, polypeptide 1 1.19213
SAA3P serum amyloid A3 pseudogene 1.19213
TSC22D3 TSC22 domain family, member 3 1.19113
CD2 CD2 molecule 1.19014
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 1.18915
HSPA4 heat shock 70kDa protein 4 1.18882
CFI complement factor I 1.18816
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase) 1.18685
ATF3 activating transcription factor 3 1.18587
WISP2 WNT1 inducible signaling pathway protein 2 1.18424
B2M beta-2-microglobulin 1.18424
ARG2 arginase 2 1.18424
REG3G regenerating islet-derived 3 gamma 1.18326
ERBB2IP erbb2 interacting protein 1.18326
CD5 CD5 molecule 1.18293
CD86 CD86 molecule 1.18293
FDPS farnesyl diphosphate synthase 1.17993
ESR1 estrogen receptor 1 1.17695
TLR3 toll-like receptor 3 1.17695
C5 complement component 5 1.17695
MYO1B myosin IB 1.17695
ADCY8 adenylate cyclase 8 (brain) 1.17629
MCOLN2 mucolipin 2 1.17596
IL7 interleukin 7 1.17333
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3 1.17333
IGF1 insulin-like growth factor 1 (somatomedin C) 1.17202
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide 1.17034
ACTG2 actin, gamma 2, smooth muscle, enteric 1.16967
MMP14 matrix metallopeptidase 14 (membrane-inserted) 1.16866
CREB1 cAMP responsive element binding protein 1 1.16833
MT2A metallothionein 2A 1.16633
PSMA4 proteasome (prosome, macropain) subunit, alpha type, 4 1.16633
TP53 tumor protein p53 1.166
HSPD1 heat shock 60kDa protein 1 (chaperonin) 1.16467
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) 1.16434
CDK1 cyclin-dependent kinase 1 1.16401
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa 1.16269
UBR4 ubiquitin protein ligase E3 component n-recognin 4 1.16269
AP2B1 adaptor-related protein complex 2, beta 1 subunit 1.16269
PPARA peroxisome proliferator-activated receptor alpha 1.16203
HAS2 hyaluronan synthase 2 1.15933
FDFT1 farnesyl-diphosphate farnesyltransferase 1 1.15797
SQLE squalene epoxidase 1.15593
IL33 interleukin 33 1.15593
CLEC4A C-type lectin domain family 4, member A 1.15357
CACNB3 calcium channel, voltage-dependent, beta 3 subunit 1.15022
AMPH amphiphysin 1.15022
ACTN2 actinin, alpha 2 1.14989
BCL2L13 BCL2-like 13 (apoptosis facilitator) 1.14989
COPE coatomer protein complex, subunit epsilon 1.14989
S100A9 S100 calcium binding protein A9 1.14954
METRNL meteorin, glial cell differentiation regulator-like 1.14954
EDNRA endothelin receptor type A 1.14747
MUC1 mucin 1, cell surface associated 1.1461
SLPI secretory leukocyte peptidase inhibitor 1.14575
THOP1 thimet oligopeptidase 1 1.14404
HSPA8 heat shock 70kDa protein 8 1.142
SPP1 secreted phosphoprotein 1 1.14166
CTGF connective tissue growth factor 1.14064
MMP1 matrix metallopeptidase 1 1.14064
RRAD Ras-related associated with diabetes 1.13963
PTGER3 prostaglandin E receptor 3 (subtype EP3) 1.13929
ENO3 enolase 3 (beta, muscle) 1.13929
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide 1.13793
PXDN peroxidasin 1.13758
MR1 major histocompatibility complex, class I-related 1.13758
GAPDH glyceraldehyde-3-phosphate dehydrogenase 1.13518
TOP2A topoisomerase (DNA) II alpha 170kDa 1.13381
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1 1.13347
BAD BCL2-associated agonist of cell death 1.13245
CSF3R colony stimulating factor 3 receptor (granulocyte) 1.13211
MAPK8 mitogen-activated protein kinase 8 1.13041
ALCAM activated leukocyte cell adhesion molecule 1.13007
RAD51 RAD51 recombinase 1.12973
ACSL4 acyl-CoA synthetase long-chain family member 4 1.12973
AQP4 aquaporin 4 1.12737
DUSP4 dual specificity phosphatase 4 1.12703
DEDD2 death effector domain containing 2 1.12668
WIF1 WNT inhibitory factor 1 1.12599
CDC20 cell division cycle 20 1.12599
SIGLEC1 sialic acid binding Ig-like lectin 1, sialoadhesin 1.1253
MRGPRF MAS-related GPR, member F 1.1253
TNN tenascin N 1.12461
HELLS helicase, lymphoid-specific 1.12391
EPHX2 epoxide hydrolase 2, cytoplasmic 1.12391
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein 1.12219
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) 1.12117
ROR1 receptor tyrosine kinase-like orphan receptor 1 1.12082
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 1.12048
PPID peptidylprolyl isomerase D 1.12048
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 1.1198
PER1 period circadian clock 1 1.11809
NFKBIZ nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta 1.11809
CSTB cystatin B (stefin B) 1.11809
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog 1.11501
TYMP thymidine phosphorylase 1.11501
NPPB natriuretic peptide B 1.11466
BCL2L11 BCL2-like 11 (apoptosis facilitator) 1.1129
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 1.1129
FKBP4 FK506 binding protein 4, 59kDa 1.1122
RNF32 ring finger protein 32 1.11186
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 1.11116
ACSL1 acyl-CoA synthetase long-chain family member 1 1.11081
PLA2G1B phospholipase A2, group IB (pancreas) 1.11011
AARS alanyl-tRNA synthetase 1.11011
IL12RB1 interleukin 12 receptor, beta 1 1.11011
IER3 immediate early response 3 1.10907
IRS1 insulin receptor substrate 1 1.10734
ANGPTL4 angiopoietin-like 4 1.10734
HDC histidine decarboxylase 1.10665
RRM1 ribonucleotide reductase M1 1.10631
CSF3 colony stimulating factor 3 (granulocyte) 1.10562
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 1.10562
TFF2 trefoil factor 2 1.10493
OMD osteomodulin 1.10459
UGCG UDP-glucose ceramide glucosyltransferase 1.10104
NCKAP5 NCK-associated protein 5 1.10033
SLC2A12 solute carrier family 2 (facilitated glucose transporter), member 12 1.10033
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 1.09998
PRICKLE1 prickle homolog 1 (Drosophila) 1.09963
MARCO macrophage receptor with collagenous structure 1.09963
CALCRL calcitonin receptor-like 1.09963
PPP1R15A protein phosphatase 1, regulatory subunit 15A 1.09822
NPY neuropeptide Y 1.09681
CENPK centromere protein K 1.08975
PIGR polymeric immunoglobulin receptor 1.08975
MME membrane metallo-endopeptidase 1.08975
HHIP hedgehog interacting protein 1.08975
MYL1 myosin, light chain 1, alkali; skeletal, fast 1.08975
TUBA1A tubulin, alpha 1a 1.08975
SEC14L3 SEC14-like 3 (S. cerevisiae) 1.08904
GSTM5 glutathione S-transferase mu 5 1.08726
TPM3 tropomyosin 3 1.08726
CPT1B carnitine palmitoyltransferase 1B (muscle) 1.08726
NCF1 neutrophil cytosolic factor 1 1.08619
CD53 CD53 molecule 1.08513
SLC26A4 solute carrier family 26 (anion exchanger), member 4 1.08513
HLF hepatic leukemia factor 1.08478
TXN thioredoxin 1.08478
NUPR1 nuclear protein, transcriptional regulator, 1 1.08442
DUSP5 dual specificity phosphatase 5 1.08442
CRYAB crystallin, alpha B 1.08442
ACTA2 actin, alpha 2, smooth muscle, aorta 1.08442
MMP13 matrix metallopeptidase 13 1.08301
IL4R interleukin 4 receptor 1.08091
LTC4S leukotriene C4 synthase 1.08091
ACOT7 acyl-CoA thioesterase 7 1.08055
MARCKSL1 MARCKS-like 1 1.08055
GATA3 GATA binding protein 3 1.07947
GSTT2 glutathione S-transferase theta 2 (gene/pseudogene) 1.07947
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 1.07947
TGFBR1 transforming growth factor, beta receptor 1 1.07696
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 1.0766
PTPRG protein tyrosine phosphatase, receptor type, G 1.07625
TRIB3 tribbles pseudokinase 3 1.07625
NPPC natriuretic peptide C 1.07589
CLEC7A C-type lectin domain family 7, member A 1.07589
CD274 CD274 molecule 1.07553
CLCA1 chloride channel accessory 1 1.07553
SDPR serum deprivation response 1.07553
JAG1 jagged 1 1.07411
AGTR1 angiotensin II receptor, type 1 1.07411
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 1.07376
GSTM3 glutathione S-transferase mu 3 (brain) 1.07305
CCR3 chemokine (C-C motif) receptor 3 1.07163
BUB1 BUB1 mitotic checkpoint serine/threonine kinase 1.07163
LTA4H leukotriene A4 hydrolase 1.07163
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) 1.07128
UBE2B ubiquitin-conjugating enzyme E2B 1.07128
ATF4 activating transcription factor 4 1.07128
ACTB actin, beta 1.06987
CX3CL1 chemokine (C-X3-C motif) ligand 1 1.06917
PSAT1 phosphoserine aminotransferase 1 1.06917
CD38 CD38 molecule 1.06917
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase 1.06917
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 1.06881
PPAP2A phosphatidic acid phosphatase type 2A 1.06698
TTN titin 1.06698
IQGAP2 IQ motif containing GTPase activating protein 2 1.06698
FABP3 fatty acid binding protein 3, muscle and heart 1.06406
NFE2L2 nuclear factor, erythroid 2-like 2 1.06333
LAMP3 lysosomal-associated membrane protein 3 1.06261
FABP5 fatty acid binding protein 5 (psoriasis-associated) 1.06188
MYH7 myosin, heavy chain 7, cardiac muscle, beta 1.06188
ADRA1B adrenoceptor alpha 1B 1.05936
FADD Fas (TNFRSF6)-associated via death domain 1.05936
TNFAIP6 tumor necrosis factor, alpha-induced protein 6 1.05936
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) 1.05936
HYDIN HYDIN, axonemal central pair apparatus protein 1.059
EFTUD2 elongation factor Tu GTP binding domain containing 2 1.05864
DICER1 dicer 1, ribonuclease type III 1.05828
UNC5B unc-5 homolog B (C. elegans) 1.05828
PSMB6 proteasome (prosome, macropain) subunit, beta type, 6 1.05828
CD72 CD72 molecule 1.05828
PPAPDC2 phosphatidic acid phosphatase type 2 domain containing 2 1.05793
CTSD cathepsin D 1.05685
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 1.05685
GNA13 guanine nucleotide binding protein (G protein), alpha 13 1.05386
LRG1 leucine-rich alpha-2-glycoprotein 1 1.05386
STEAP4 STEAP family member 4 1.05386
SCD stearoyl-CoA desaturase (delta-9-desaturase) 1.05386
ACLY ATP citrate lyase 1.052
GHR growth hormone receptor 1.052
CXCL12 chemokine (C-X-C motif) ligand 12 1.05052
IFI27 interferon, alpha-inducible protein 27 1.05015
SLC24A4 solute carrier family 24 (sodium/potassium/calcium exchanger), member 4 1.05015
DBF4 DBF4 zinc finger 1.04978
FFAR2 free fatty acid receptor 2 1.04941
RAB40C RAB40C, member RAS oncogene family 1.04941
LY96 lymphocyte antigen 96 1.04941
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) 1.04904
BANK1 B-cell scaffold protein with ankyrin repeats 1 1.04904
ZRANB3 zinc finger, RAN-binding domain containing 3 1.04868
CP ceruloplasmin (ferroxidase) 1.04757
BDNF brain-derived neurotrophic factor 1.04757
CDCA7 cell division cycle associated 7 1.04538
BASP1 brain abundant, membrane attached signal protein 1 1.04538
CD80 CD80 molecule 1.04501
HDAC1 histone deacetylase 1 1.04501
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 1.04501
HNF4A hepatocyte nuclear factor 4, alpha 1.04501
CCR2 chemokine (C-C motif) receptor 2 1.04276
LIF leukemia inhibitory factor 1.04276
ADORA2A adenosine A2a receptor 1.04276
KLF4 Kruppel-like factor 4 (gut) 1.04239
HNMT histamine N-methyltransferase 1.04201
STAT5B signal transducer and activator of transcription 5B 1.04163
MMP8 matrix metallopeptidase 8 1.04126
FAT3 FAT atypical cadherin 3 1.04051
ORM1 orosomucoid 1 1.04051
IL2RA interleukin 2 receptor, alpha 1.04014
SGCG sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) 1.04014
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 1.04014
PLIN2 perilipin 2 1.04014
CLEC3B C-type lectin domain family 3, member B 1.03976
MCOLN3 mucolipin 3 1.03976
ATF2 activating transcription factor 2 1.03789
KCNJ8 potassium channel, inwardly rectifying subfamily J, member 8 1.03789
NT5DC2 5'-nucleotidase domain containing 2 1.03752
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) 1.03752
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit) 1.03715
MAP3K6 mitogen-activated protein kinase kinase kinase 6 1.03715
GPR17 G protein-coupled receptor 17 1.0353
NQO1 NAD(P)H dehydrogenase, quinone 1 1.03419
PDLIM1 PDZ and LIM domain 1 1.03382
PDE4D phosphodiesterase 4D, cAMP-specific 1.03382
PTGR1 prostaglandin reductase 1 1.03345
NOX4 NADPH oxidase 4 1.03345
IGHE immunoglobulin heavy constant epsilon 1.03308
CD19 CD19 molecule 1.03159
CAMSAP2 calmodulin regulated spectrin-associated protein family, member 2 1.03159
VGLL3 vestigial-like family member 3 1.03159
ICOS inducible T-cell co-stimulator 1.03159
MSMO1 methylsterol monooxygenase 1 1.03122
MCM2 minichromosome maintenance complex component 2 1.03122
HMCN1 hemicentin 1 1.03122
TMEM173 transmembrane protein 173 1.03122
XRRA1 X-ray radiation resistance associated 1 1.03046
SFTPC surfactant protein C 1.03009
CD8A CD8a molecule 1.02971
PTN pleiotrophin 1.02971
F8 coagulation factor VIII, procoagulant component 1.02971
LRP2 low density lipoprotein receptor-related protein 2 1.02971
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase 1.02933
PFKL phosphofructokinase, liver 1.02933
MCM6 minichromosome maintenance complex component 6 1.02896
CD300E CD300e molecule 1.02896
GGT1 gamma-glutamyltransferase 1 1.02671
EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa 1.02671
ACADM acyl-CoA dehydrogenase, C-4 to C-12 straight chain 1.02671
THRA thyroid hormone receptor, alpha 1.02671
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A 1.02671
ADORA3 adenosine A3 receptor 1.02634
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5 1.02596
IRF9 interferon regulatory factor 9 1.02559
GSK3B glycogen synthase kinase 3 beta 1.0241
FNDC1 fibronectin type III domain containing 1 1.0241
SLC22A2 solute carrier family 22 (organic cation transporter), member 2 1.0241
AHSG alpha-2-HS-glycoprotein 1.02225
VCP valosin containing protein 1.02225
PSMB2 proteasome (prosome, macropain) subunit, beta type, 2 1.02225
MB myoglobin 1.02225
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B 1.02003
IDI1 isopentenyl-diphosphate delta isomerase 1 1.02003
JUP junction plakoglobin 1.01852
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) 1.01852
H3F3B H3 histone, family 3B (H3.3B) 1.01852
F2R coagulation factor II (thrombin) receptor 1.01814
PRKCA protein kinase C, alpha 1.01814
GSTM2 glutathione S-transferase mu 2 (muscle) 1.01814
GCH1 GTP cyclohydrolase 1 1.01814
ASPH aspartate beta-hydroxylase 1.01814
SRC SRC proto-oncogene, non-receptor tyrosine kinase 1.01663
TK1 thymidine kinase 1, soluble 1.01587
USP53 ubiquitin specific peptidase 53 1.01549
JAM3 junctional adhesion molecule 3 1.01549
GSTA3 glutathione S-transferase alpha 3 1.01512
PTGIS prostaglandin I2 (prostacyclin) synthase 1.01474
RPS19 ribosomal protein S19 1.01474
FKBP5 FK506 binding protein 5 1.01399
FOSB FBJ murine osteosarcoma viral oncogene homolog B 1.01399
NR4A2 nuclear receptor subfamily 4, group A, member 2 1.01399
TCF19 transcription factor 19 1.01099
CXCL11 chemokine (C-X-C motif) ligand 11 1.01099
CRP C-reactive protein, pentraxin-related 1.01099