Bronchial Hyperreactivity Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link https://www.disgenet.org/browser/0/1/0/C0085129
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Genes

103 genes associated with the disease Bronchial Hyperreactivity in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ADAM33 ADAM metallopeptidase domain 33
ADAMTS12 ADAM metallopeptidase with thrombospondin type 1 motif, 12
ADRB2 adrenoceptor beta 2, surface
AREG amphiregulin
CALCA calcitonin-related polypeptide alpha
CASP10 caspase 10, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CAV1 caveolin 1, caveolae protein, 22kDa
CCL2 chemokine (C-C motif) ligand 2
CCL3 chemokine (C-C motif) ligand 3
CCL5 chemokine (C-C motif) ligand 5
CCR2 chemokine (C-C motif) receptor 2
CCR3 chemokine (C-C motif) receptor 3
CD14 CD14 molecule
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CHRM3 cholinergic receptor, muscarinic 3
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal)
CLDN18 claudin 18
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL8 chemokine (C-X-C motif) ligand 8
CYSLTR1 cysteinyl leukotriene receptor 1
DNAH9 dynein, axonemal, heavy chain 9
DPP10 dipeptidyl-peptidase 10 (non-functional)
ESR1 estrogen receptor 1
F11R F11 receptor
F2RL1 coagulation factor II (thrombin) receptor-like 1
FCER2 Fc fragment of IgE, low affinity II, receptor for (CD23)
FEV FEV (ETS oncogene family)
GATA3 GATA binding protein 3
GSDMB gasdermin B
GSTK1 glutathione S-transferase kappa 1
GSTP1 glutathione S-transferase pi 1
HBEGF heparin-binding EGF-like growth factor
HHIP hedgehog interacting protein
HLA-DOA major histocompatibility complex, class II, DO alpha
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HLA-G major histocompatibility complex, class I, G
HNMT histamine N-methyltransferase
HPGDS hematopoietic prostaglandin D synthase
ICAM1 intercellular adhesion molecule 1
IFNG interferon, gamma
IL10 interleukin 10
IL13 interleukin 13
IL1RN interleukin 1 receptor antagonist
IL31 interleukin 31
IL33 interleukin 33
IL4 interleukin 4
IL4R interleukin 4 receptor
IL5 interleukin 5
IL9 interleukin 9
IL9R interleukin 9 receptor
IRF1 interferon regulatory factor 1
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
KAT5 K(lysine) acetyltransferase 5
LTA lymphotoxin alpha
LTC4S leukotriene C4 synthase
MAML3 mastermind-like 3 (Drosophila)
MAPK8 mitogen-activated protein kinase 8
MMP1 matrix metallopeptidase 1
MS4A3 membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)
NDUFA2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa
NGF nerve growth factor (beta polypeptide)
NLRP3 NLR family, pyrin domain containing 3
NOS2 nitric oxide synthase 2, inducible
NPSR1 neuropeptide S receptor 1
NR1I2 nuclear receptor subfamily 1, group I, member 2
ORMDL3 ORMDL sphingolipid biosynthesis regulator 3
P2RX4 purinergic receptor P2X, ligand gated ion channel, 4
PCDH1 protocadherin 1
PDE4A phosphodiesterase 4A, cAMP-specific
PHF11 PHD finger protein 11
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PPP1R42 protein phosphatase 1, regulatory subunit 42
PROC protein C (inactivator of coagulation factors Va and VIIIa)
PTGDR prostaglandin D2 receptor (DP)
PTGDR2 prostaglandin D2 receptor 2
PTGER4 prostaglandin E receptor 4 (subtype EP4)
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
PTTG1IP pituitary tumor-transforming 1 interacting protein
RBM45 RNA binding motif protein 45
RNASE3 ribonuclease, RNase A family, 3
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin)
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SFTPD surfactant protein D
SLC52A1 solute carrier family 52 (riboflavin transporter), member 1
SLCO6A1 solute carrier organic anion transporter family, member 6A1
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal
SOD2 superoxide dismutase 2, mitochondrial
SOD3 superoxide dismutase 3, extracellular
TAC1 tachykinin, precursor 1
TACR1 tachykinin receptor 1
TBX21 T-box 21
TLR4 toll-like receptor 4
TNF tumor necrosis factor
TRPA1 transient receptor potential cation channel, subfamily A, member 1
TRPV1 transient receptor potential cation channel, subfamily V, member 1
UQCRC2 ubiquinol-cytochrome c reductase core protein II
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VEGFA vascular endothelial growth factor A
VIP vasoactive intestinal peptide