Bronchiectasis Gene Set

Dataset CTD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description A bronchial disease that is a chronic inflammatory condition of one or more bronchi or bronchioles marked by dilatation and loss of elasticity of the walls resulting from damage to the airway wall leading to the formation of small sacs on the bronchial wall and impairment of cilia mobility in the lung. Inflammation of the bronchial wall increases mucus secretion which serves as a breeding ground for bacteria. Bronchiectasis is caused by repeated respiratory infections, immune deficiency disorders, hereditary disorders (cystic fibrosis or primary ciliary dyskinesia), mechanical factors (inhaled object or a lung tumor) or inhaling toxic substances. (Human Disease Ontology, DOID_9563)
External Link http://ctdbase.org/detail.go?type=disease&acc=MESH:D001987
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Genes

3 genes/proteins associated with the disease Bronchiectasis from the curated CTD Gene-Disease Associations dataset.

Symbol Name Standardized Value
TNF tumor necrosis factor 2.88009
ICAM1 intercellular adhesion molecule 1 2.88009
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 2.88009