Bronchiectasis Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores 2025
Category disease or phenotype associations
Type disease
Description A bronchial disease that is a chronic inflammatory condition of one or more bronchi or bronchioles marked by dilatation and loss of elasticity of the walls resulting from damage to the airway wall leading to the formation of small sacs on the bronchial wall and impairment of cilia mobility in the lung. Inflammation of the bronchial wall increases mucus secretion which serves as a breeding ground for bacteria. Bronchiectasis is caused by repeated respiratory infections, immune deficiency disorders, hereditary disorders (cystic fibrosis or primary ciliary dyskinesia), mechanical factors (inhaled object or a lung tumor) or inhaling toxic substances. (Human Disease Ontology, DOID_9563)
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Genes

702 genes co-occuring with the disease Bronchiectasis in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.

Symbol Name Standardized Value
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) 3.308
ELANE elastase, neutrophil expressed 3.08
CRP C-reactive protein, pentraxin-related 3.0
DNAH5 dynein, axonemal, heavy chain 5 2.948
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 2.881
DNAH11 dynein, axonemal, heavy chain 11 2.839
CCDC40 coiled-coil domain containing 40 2.827
DNAI1 dynein, axonemal, intermediate chain 1 2.824
CD4 CD4 molecule 2.764
MUC5B mucin 5B, oligomeric mucus/gel-forming 2.745
CXCL8 chemokine (C-X-C motif) ligand 8 2.73
CCDC39 coiled-coil domain containing 39 2.717
RSPH4A radial spoke head 4 homolog A (Chlamydomonas) 2.701
IL6 interleukin 6 2.65
RSPH9 radial spoke head 9 homolog (Chlamydomonas) 2.618
TNF tumor necrosis factor 2.603
DNAI2 dynein, axonemal, intermediate chain 2 2.599
SFTPD surfactant protein D 2.572
CD8A CD8a molecule 2.561
CCNO cyclin O 2.546
RSPH1 radial spoke head 1 homolog (Chlamydomonas) 2.541
DNAAF1 dynein, axonemal, assembly factor 1 2.538
MUC1 mucin 1, cell surface associated 2.538
IL5 interleukin 5 2.521
IFNG interferon, gamma 2.52
MUC5AC mucin 5AC, oligomeric mucus/gel-forming 2.518
IL1B interleukin 1, beta 2.505
DNAAF3 dynein, axonemal, assembly factor 3 2.497
PRTN3 proteinase 3 2.487
ALB albumin 2.465
DNAAF2 dynein, axonemal, assembly factor 2 2.462
MPO myeloperoxidase 2.451
IL13 interleukin 13 2.442
DRC1 dynein regulatory complex subunit 1 2.376
IL4 interleukin 4 2.376
DOCK8 dedicator of cytokinesis 8 2.369
CTSC cathepsin C 2.364
DNAAF5 dynein, axonemal, assembly factor 5 2.363
IL17A interleukin 17A 2.359
HYDIN HYDIN, axonemal central pair apparatus protein 2.349
DNAH9 dynein, axonemal, heavy chain 9 2.339
IL10 interleukin 10 2.305
CD19 CD19 molecule 2.282
CCDC65 coiled-coil domain containing 65 2.268
DNALI1 dynein, axonemal, light intermediate chain 1 2.261
CTSG cathepsin G 2.261
DNAAF4 dynein axonemal assembly factor 4 2.246
ELN elastin 2.227
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 2.213
TGFB1 transforming growth factor, beta 1 2.212
GAS8 growth arrest-specific 8 2.21
ACE angiotensin I converting enzyme 2.202
DNAH1 dynein, axonemal, heavy chain 1 2.199
MCIDAS multiciliate differentiation and DNA synthesis associated cell cycle protein 2.164
SPAG1 sperm associated antigen 1 2.161
ACE2 angiotensin I converting enzyme 2 2.155
FOXJ1 forkhead box J1 2.14
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B 2.135
IL1A interleukin 1, alpha 2.131
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 2.131
CD27 CD27 molecule 2.13
LRBA LPS-responsive vesicle trafficking, beach and anchor containing 2.127
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide 2.126
IFIH1 interferon induced with helicase C domain 1 2.123
MMP9 matrix metallopeptidase 9 2.121
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide 2.103
NME8 NME/NM23 family member 8 2.103
SFTPC surfactant protein C 2.097
GPT glutamic-pyruvate transaminase (alanine aminotransferase) 2.097
HSPD1 heat shock 60kDa protein 1 (chaperonin) 2.092
CFAP298 cilia and flagella associated protein 298 2.09
ZMYND10 zinc finger, MYND-type containing 10 2.086
SCNN1B sodium channel, non voltage gated 1 beta subunit 2.084
MMP8 matrix metallopeptidase 8 2.065
IL2 interleukin 2 2.062
TRIM21 tripartite motif containing 21 2.029
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 2.018
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b) 2.014
CSF3 colony stimulating factor 3 (granulocyte) 2.008
IL5RA interleukin 5 receptor, alpha 2.002
SLPI secretory leukocyte peptidase inhibitor 1.997
OFD1 oral-facial-digital syndrome 1 1.993
SLC26A9 solute carrier family 26 (anion exchanger), member 9 1.985
BTK Bruton agammaglobulinemia tyrosine kinase 1.984
MBL2 mannose-binding lectin (protein C) 2, soluble 1.971
FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a) 1.969
TLR2 toll-like receptor 2 1.965
TLR4 toll-like receptor 4 1.958
CFAP300 cilia and flagella associated protein 300 1.958
CXCL10 chemokine (C-X-C motif) ligand 10 1.949
TSLP thymic stromal lymphopoietin 1.947
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin) 1.944
CXCR2 chemokine (C-X-C motif) receptor 2 1.942
IL33 interleukin 33 1.941
DNASE1 deoxyribonuclease I 1.94
SFTPA2 surfactant protein A2 1.931
STAT1 signal transducer and activator of transcription 1, 91kDa 1.928
SERPINB10 serpin peptidase inhibitor, clade B (ovalbumin), member 10 1.927
RPGR retinitis pigmentosa GTPase regulator 1.925
RSPH3 radial spoke 3 homolog (Chlamydomonas) 1.907
CAMP cathelicidin antimicrobial peptide 1.897
LTF lactotransferrin 1.896
NCAM1 neural cell adhesion molecule 1 1.894
NPPB natriuretic peptide B 1.891
CCL2 chemokine (C-C motif) ligand 2 1.878
RNASE3 ribonuclease, RNase A family, 3 1.873
PGM3 phosphoglucomutase 3 1.872
CR2 complement component (3d/Epstein Barr virus) receptor 2 1.865
BPI bactericidal/permeability-increasing protein 1.855
SPEF2 sperm flagellar 2 1.855
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 1.847
FN1 fibronectin 1 1.844
IFNA1 interferon, alpha 1 1.829
IL22 interleukin 22 1.825
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1 1.822
MMP12 matrix metallopeptidase 12 1.821
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta 1.816
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 1.814
CD40LG CD40 ligand 1.812
CFAP221 cilia and flagella associated protein 221 1.806
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 1.804
IL9 interleukin 9 1.801
BPIFB1 BPI fold containing family B, member 1 1.797
LRRC56 leucine rich repeat containing 56 1.796
CXCR1 chemokine (C-X-C motif) receptor 1 1.794
CKM creatine kinase, muscle 1.792
CKMT2 creatine kinase, mitochondrial 2 (sarcomeric) 1.79
CKMT1B creatine kinase, mitochondrial 1B 1.789
CKB creatine kinase, brain 1.786
ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3 1.785
F2 coagulation factor II (thrombin) 1.782
ICAM1 intercellular adhesion molecule 1 1.778
MMP7 matrix metallopeptidase 7 1.773
SFTPB surfactant protein B 1.773
CTLA4 cytotoxic T-lymphocyte-associated protein 4 1.77
F3 coagulation factor III (thromboplastin, tissue factor) 1.769
ZNF341 zinc finger protein 341 1.764
TNFRSF13C tumor necrosis factor receptor superfamily, member 13C 1.763
CCL11 chemokine (C-C motif) ligand 11 1.762
TIMP1 TIMP metallopeptidase inhibitor 1 1.753
IL4R interleukin 4 receptor 1.752
PTPRC protein tyrosine phosphatase, receptor type, C 1.752
CCL3 chemokine (C-C motif) ligand 3 1.751
IL18 interleukin 18 1.741
POSTN periostin, osteoblast specific factor 1.733
ADA adenosine deaminase 1.729
TOLLIP toll interacting protein 1.729
CCL5 chemokine (C-C motif) ligand 5 1.729
IL17F interleukin 17F 1.721
FOXP3 forkhead box P3 1.709
EGFR epidermal growth factor receptor 1.702
IFNB1 interferon, beta 1, fibroblast 1.694
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 1.693
NEK10 NIMA-related kinase 10 1.69
MTOR mechanistic target of rapamycin (serine/threonine kinase) 1.685
INS insulin 1.683
FAM13A family with sequence similarity 13, member A 1.681
PDE4A phosphodiesterase 4A, cAMP-specific 1.68
DNAH7 dynein, axonemal, heavy chain 7 1.674
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b 1.67
NKX2-1 NK2 homeobox 1 1.67
KCNRG potassium channel regulator 1.665
RAG1 recombination activating gene 1 1.665
MMP1 matrix metallopeptidase 1 1.665
PADI4 peptidyl arginine deiminase, type IV 1.662
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) 1.661
AIRE autoimmune regulator 1.659
GPT2 glutamic pyruvate transaminase (alanine aminotransferase) 2 1.658
NLRC4 NLR family, CARD domain containing 4 1.655
CD28 CD28 molecule 1.652
PARN poly(A)-specific ribonuclease 1.646
GAPDH glyceraldehyde-3-phosphate dehydrogenase 1.638
CLEC7A C-type lectin domain family 7, member A 1.632
DNAJB13 DnaJ (Hsp40) homolog, subfamily B, member 13 1.626
NEB nebulin 1.625
CCL17 chemokine (C-C motif) ligand 17 1.621
SELL selectin L 1.621
RAG2 recombination activating gene 2 1.62
CTSS cathepsin S 1.618
TMPRSS2 transmembrane protease, serine 2 1.618
IFT88 intraflagellar transport 88 1.616
DNAH6 dynein, axonemal, heavy chain 6 1.614
RTEL1 regulator of telomere elongation helicase 1 1.612
ICOS inducible T-cell co-stimulator 1.612
SFTPA1 surfactant protein A1 1.609
TLR5 toll-like receptor 5 1.607
SCNN1G sodium channel, non voltage gated 1 gamma subunit 1.606
MYD88 myeloid differentiation primary response 88 1.605
CCR7 chemokine (C-C motif) receptor 7 1.605
BPIFA1 BPI fold containing family A, member 1 1.601
IL7 interleukin 7 1.593
CYBB cytochrome b-245, beta polypeptide 1.592
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 1.592
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.582
DHRS2 dehydrogenase/reductase (SDR family) member 2 1.58
TYK2 tyrosine kinase 2 1.577
PI3 peptidase inhibitor 3, skin-derived 1.573
HPS4 Hermansky-Pudlak syndrome 4 1.572
TLR9 toll-like receptor 9 1.571
PKD1 polycystic kidney disease 1 (autosomal dominant) 1.568
DCLRE1C DNA cross-link repair 1C 1.557
GAS2L2 growth arrest-specific 2 like 2 1.556
CD40 CD40 molecule, TNF receptor superfamily member 5 1.554
IL7R interleukin 7 receptor 1.553
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 1.551
TLR3 toll-like receptor 3 1.549
RFXANK regulatory factor X-associated ankyrin-containing protein 1.545
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) 1.543
CD68 CD68 molecule 1.539
ADRB2 adrenoceptor beta 2, surface 1.537
KRT5 keratin 5, type II 1.536
CARD9 caspase recruitment domain family, member 9 1.534
AK7 adenylate kinase 7 1.529
CD274 CD274 molecule 1.522
ACTB actin, beta 1.521
PZP pregnancy-zone protein 1.52
TTR transthyretin 1.517
IL15 interleukin 15 1.516
IFNA2 interferon, alpha 2 1.516
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma 1.512
STK4 serine/threonine kinase 4 1.511
SAA1 serum amyloid A1 1.505
CD38 CD38 molecule 1.504
CARD11 caspase recruitment domain family, member 11 1.503
CXCR4 chemokine (C-X-C motif) receptor 4 1.503
SPAG6 sperm associated antigen 6 1.501
PXDN peroxidasin 1.498
EPX eosinophil peroxidase 1.496
FGF10 fibroblast growth factor 10 1.496
PXDNL peroxidasin-like 1.495
PKD1L1 polycystic kidney disease 1 like 1 1.494
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta 1.492
MMP2 matrix metallopeptidase 2 1.489
TERT telomerase reverse transcriptase 1.488
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 1.487
HHAT hedgehog acyltransferase 1.487
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) 1.485
CFAP53 cilia and flagella associated protein 53 1.484
CXCL2 chemokine (C-X-C motif) ligand 2 1.482
MUC2 mucin 2, oligomeric mucus/gel-forming 1.482
FGF7 fibroblast growth factor 7 1.48
CD34 CD34 molecule 1.48
SAA2 serum amyloid A2 1.479
CLCA1 chloride channel accessory 1 1.477
GATA2 GATA binding protein 2 1.474
PIGR polymeric immunoglobulin receptor 1.471
IL17RA interleukin 17 receptor A 1.47
CXCL5 chemokine (C-X-C motif) ligand 5 1.47
IL12RB1 interleukin 12 receptor, beta 1 1.469
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 1.468
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 1.464
FCN2 ficolin (collagen/fibrinogen domain containing lectin) 2 1.462
LEFTY2 left-right determination factor 2 1.462
CEACAM8 carcinoembryonic antigen-related cell adhesion molecule 8 1.459
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) 1.459
EGF epidermal growth factor 1.459
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha 1.458
NLRP3 NLR family, pyrin domain containing 3 1.457
DNAH8 dynein, axonemal, heavy chain 8 1.455
JUN jun proto-oncogene 1.455
SPDEF SAM pointed domain containing ETS transcription factor 1.453
ITK IL2-inducible T-cell kinase 1.453
JAK3 Janus kinase 3 1.452
INVS inversin 1.45
CXCR3 chemokine (C-X-C motif) receptor 3 1.45
CXCL9 chemokine (C-X-C motif) ligand 9 1.449
CCL4 chemokine (C-C motif) ligand 4 1.448
PRF1 perforin 1 (pore forming protein) 1.444
TINF2 TERF1 (TRF1)-interacting nuclear factor 2 1.442
DNAH2 dynein, axonemal, heavy chain 2 1.442
IL2RG interleukin 2 receptor, gamma 1.439
CD86 CD86 molecule 1.439
ATM ATM serine/threonine kinase 1.438
CCN2 cellular communication network factor 2 1.436
IFNGR1 interferon gamma receptor 1 1.434
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma 1.432
HHIP hedgehog interacting protein 1.43
ZIC3 Zic family member 3 1.428
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1 1.426
IL21R interleukin 21 receptor 1.422
SELE selectin E 1.421
IL1R1 interleukin 1 receptor, type I 1.419
JAK1 Janus kinase 1 1.418
CD80 CD80 molecule 1.417
SSB Sjogren syndrome antigen B (autoantigen La) 1.416
WAS Wiskott-Aldrich syndrome 1.416
SNRNP70 small nuclear ribonucleoprotein 70kDa (U1) 1.413
ALK anaplastic lymphoma receptor tyrosine kinase 1.412
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 1.411
IFNA17 interferon, alpha 17 1.41
VCAM1 vascular cell adhesion molecule 1 1.409
SAA2-SAA4 SAA2-SAA4 readthrough 1.406
AGBL2 ATP/GTP binding protein-like 2 1.406
DNAH17 dynein, axonemal, heavy chain 17 1.405
CASP1 caspase 1, apoptosis-related cysteine peptidase 1.404
TAC1 tachykinin, precursor 1 1.404
STK36 serine/threonine kinase 36 1.404
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit) 1.403
MAGT1 magnesium transporter 1 1.402
CEP164 centrosomal protein 164kDa 1.401
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 1.4
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced 1.399
MORC3 MORC family CW-type zinc finger 3 1.398
AICDA activation-induced cytidine deaminase 1.398
CHIT1 chitinase 1 (chitotriosidase) 1.397
ENO2 enolase 2 (gamma, neuronal) 1.395
AZU1 azurocidin 1 1.395
P2RX3 purinergic receptor P2X, ligand gated ion channel, 3 1.388
IL3 interleukin 3 1.388
HMOX1 heme oxygenase 1 1.388
IL2RA interleukin 2 receptor, alpha 1.388
PECAM1 platelet/endothelial cell adhesion molecule 1 1.388
HBZ hemoglobin, zeta 1.387
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 1.385
GRP gastrin-releasing peptide 1.376
CFAP57 cilia and flagella associated protein 57 1.371
TLR7 toll-like receptor 7 1.37
LCN2 lipocalin 2 1.37
CAMLG calcium modulating ligand 1.367
GC group-specific component (vitamin D binding protein) 1.366
EDN1 endothelin 1 1.366
B2M beta-2-microglobulin 1.366
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1 1.364
C3 complement component 3 1.363
CTRB2 chymotrypsinogen B2 1.362
MUC4 mucin 4, cell surface associated 1.359
EXOSC10 exosome component 10 1.357
SH2D1A SH2 domain containing 1A 1.357
SAA4 serum amyloid A4, constitutive 1.356
CTRB1 chymotrypsinogen B1 1.356
IFNGR2 interferon gamma receptor 2 (interferon gamma transducer 1) 1.355
FGF9 fibroblast growth factor 9 1.355
FGF16 fibroblast growth factor 16 1.352
HPS3 Hermansky-Pudlak syndrome 3 1.351
NOD2 nucleotide-binding oligomerization domain containing 2 1.351
SDC1 syndecan 1 1.348
TLR1 toll-like receptor 1 1.347
PTX3 pentraxin 3, long 1.345
IFNA21 interferon, alpha 21 1.345
TRIM33 tripartite motif containing 33 1.344
IFNA5 interferon, alpha 5 1.343
LUM lumican 1.343
IFNA13 interferon, alpha 13 1.342
PLG plasminogen 1.342
CD163 CD163 molecule 1.342
IFNA4 interferon, alpha 4 1.34
IFT46 intraflagellar transport 46 1.339
IFNA16 interferon, alpha 16 1.339
IFNA10 interferon, alpha 10 1.339
FGF6 fibroblast growth factor 6 1.339
IFNA8 interferon, alpha 8 1.338
FGF3 fibroblast growth factor 3 1.337
FGF5 fibroblast growth factor 5 1.337
FGF18 fibroblast growth factor 18 1.337
DEFB4A defensin, beta 4A 1.335
FGF22 fibroblast growth factor 22 1.335
FGF17 fibroblast growth factor 17 1.334
CELA1 chymotrypsin-like elastase family, member 1 1.334
CXCR5 chemokine (C-X-C motif) receptor 5 1.333
FGF4 fibroblast growth factor 4 1.333
IFNA7 interferon, alpha 7 1.332
IFNA14 interferon, alpha 14 1.332
IFNA6 interferon, alpha 6 1.331
FGF20 fibroblast growth factor 20 1.331
PKD2 polycystic kidney disease 2 (autosomal dominant) 1.33
CXCL12 chemokine (C-X-C motif) ligand 12 1.33
ANO1 anoctamin 1, calcium activated chloride channel 1.329
DAW1 dynein assembly factor with WDR repeat domains 1 1.328
NCF1 neutrophil cytosolic factor 1 1.325
SRC SRC proto-oncogene, non-receptor tyrosine kinase 1.324
REN renin 1.324
CFAP43 cilia and flagella associated protein 43 1.323
FGF8 fibroblast growth factor 8 (androgen-induced) 1.322
MME membrane metallo-endopeptidase 1.321
USB1 U6 snRNA biogenesis 1 1.32
CARMIL2 capping protein regulator and myosin 1 linker 2 1.318
TGFA transforming growth factor, alpha 1.316
HPS5 Hermansky-Pudlak syndrome 5 1.314
TP53 tumor protein p53 1.314
NCF4 neutrophil cytosolic factor 4, 40kDa 1.313
IL6R interleukin 6 receptor 1.313
CD1B CD1b molecule 1.309
CD1C CD1c molecule 1.306
CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase 1.306
B3GAT1 beta-1,3-glucuronyltransferase 1 1.306
PDCD1 programmed cell death 1 1.306
CXCL13 chemokine (C-X-C motif) ligand 13 1.305
TTC12 tetratricopeptide repeat domain 12 1.303
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) 1.303
DKC1 dyskeratosis congenita 1, dyskerin 1.3
SPAG17 sperm associated antigen 17 1.3
MMP3 matrix metallopeptidase 3 1.3
CD5 CD5 molecule 1.299
LEP leptin 1.298
ESX1 ESX homeobox 1 1.298
AGTR2 angiotensin II receptor, type 2 1.295
CD69 CD69 molecule 1.293
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) 1.292
GMNC geminin coiled-coil domain containing 1.291
DUOX1 dual oxidase 1 1.289
NOS2 nitric oxide synthase 2, inducible 1.288
CD79A CD79a molecule, immunoglobulin-associated alpha 1.286
IL11 interleukin 11 1.285
FCGRT Fc fragment of IgG, receptor, transporter, alpha 1.285
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) 1.283
ORMDL3 ORMDL sphingolipid biosynthesis regulator 3 1.283
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 1.282
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 1.282
CCL20 chemokine (C-C motif) ligand 20 1.281
MNS1 meiosis-specific nuclear structural 1 1.281
KNG1 kininogen 1 1.278
MB myoglobin 1.277
IL31RA interleukin 31 receptor A 1.277
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific) 1.277
CD63 CD63 molecule 1.275
CCRL2 chemokine (C-C motif) receptor-like 2 1.275
HP haptoglobin 1.274
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) 1.273
BEST2 bestrophin 2 1.272
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) 1.272
PADI2 peptidyl arginine deiminase, type II 1.27
SLC26A4 solute carrier family 26 (anion exchanger), member 4 1.27
STAT5B signal transducer and activator of transcription 5B 1.269
CCL26 chemokine (C-C motif) ligand 26 1.268
MALT1 MALT1 paracaspase 1.267
HDAC2 histone deacetylase 2 1.267
CCR6 chemokine (C-C motif) receptor 6 1.267
TBX21 T-box 21 1.263
PDE5A phosphodiesterase 5A, cGMP-specific 1.262
ADAM17 ADAM metallopeptidase domain 17 1.262
ADAM33 ADAM metallopeptidase domain 33 1.262
CD1D CD1d molecule 1.259
MUC20 mucin 20, cell surface associated 1.258
CD1A CD1a molecule 1.258
DYNLRB2 dynein, light chain, roadblock-type 2 1.257
JAK2 Janus kinase 2 1.257
CCDC63 coiled-coil domain containing 63 1.256
CD81 CD81 molecule 1.256
FBN1 fibrillin 1 1.252
IL1RN interleukin 1 receptor antagonist 1.252
MAPK3 mitogen-activated protein kinase 3 1.25
DNAH10 dynein, axonemal, heavy chain 10 1.249
RFX2 regulatory factor X, 2 (influences HLA class II expression) 1.247
HMGB1 high mobility group box 1 1.245
IRF3 interferon regulatory factor 3 1.242
NME5 NME/NM23 family member 5 1.241
CLC Charcot-Leyden crystal galectin 1.238
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa 1.238
CD1E CD1e molecule 1.237
SELP selectin P (granule membrane protein 140kDa, antigen CD62) 1.236
NODAL nodal growth differentiation factor 1.232
ADIPOQ adiponectin, C1Q and collagen domain containing 1.229
PRSS57 protease, serine, 57 1.226
AGER advanced glycosylation end product-specific receptor 1.224
AP3B1 adaptor-related protein complex 3, beta 1 subunit 1.223
TOR1A torsin family 1, member A (torsin A) 1.222
ATP11A ATPase, class VI, type 11A 1.221
HLA-A major histocompatibility complex, class I, A 1.221
ARMC2 armadillo repeat containing 2 1.218
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 1.218
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) 1.218
PTAFR platelet-activating factor receptor 1.217
LGALS3 lectin, galactoside-binding, soluble, 3 1.217
MUC7 mucin 7, secreted 1.213
PF4 platelet factor 4 1.213
DEFB4B defensin, beta 4B 1.211
FCN3 ficolin (collagen/fibrinogen domain containing) 3 1.21
CDHR3 cadherin-related family member 3 1.209
RFXAP regulatory factor X-associated protein 1.209
KRT19 keratin 19, type I 1.206
POMC proopiomelanocortin 1.206
HCRT hypocretin (orexin) neuropeptide precursor 1.206
SMAD2 SMAD family member 2 1.206
CFAP74 cilia and flagella associated protein 74 1.205
FURIN furin (paired basic amino acid cleaving enzyme) 1.205
DPP9 dipeptidyl-peptidase 9 1.204
ISG15 ISG15 ubiquitin-like modifier 1.204
FLCN folliculin 1.203
IGF1 insulin-like growth factor 1 (somatomedin C) 1.203
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 1.202
CHGA chromogranin A 1.201
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 1.201
CYBA cytochrome b-245, alpha polypeptide 1.2
LOC102723407 putative V-set and immunoglobulin domain-containing-like protein IGHV4OR15-8 1.2
CSF2RA colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) 1.199
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal) 1.198
CLEC6A C-type lectin domain family 6, member A 1.197
NHEJ1 nonhomologous end-joining factor 1 1.196
STAT4 signal transducer and activator of transcription 4 1.195
MRC1 mannose receptor, C type 1 1.194
TG thyroglobulin 1.193
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 1.192
DAND5 DAN domain family member 5, BMP antagonist 1.192
SMAD3 SMAD family member 3 1.191
LTA lymphotoxin alpha 1.191
THBD thrombomodulin 1.187
A2M alpha-2-macroglobulin 1.186
CFAP52 cilia and flagella associated protein 52 1.186
SYP synaptophysin 1.185
SPAG16 sperm associated antigen 16 1.185
HARS1 histidyl-tRNA synthetase 1 1.184
TLR6 toll-like receptor 6 1.184
MEFV Mediterranean fever 1.182
IRF8 interferon regulatory factor 8 1.182
KIF3A kinesin family member 3A 1.181
HLA-B major histocompatibility complex, class I, B 1.181
IFNAR1 interferon (alpha, beta and omega) receptor 1 1.18
RFX5 regulatory factor X, 5 (influences HLA class II expression) 1.176
IFT20 intraflagellar transport 20 1.174
BLOC1S3 biogenesis of lysosomal organelles complex-1, subunit 3 1.174
IRAK4 interleukin-1 receptor-associated kinase 4 1.171
BCR breakpoint cluster region 1.171
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog 1.17
CASP3 caspase 3, apoptosis-related cysteine peptidase 1.168
CTSL cathepsin L 1.168
RO60 Ro60, Y RNA binding protein 1.166
FOXA2 forkhead box A2 1.166
IL17RC interleukin 17 receptor C 1.165
PRKACB protein kinase, cAMP-dependent, catalytic, beta 1.165
HPS6 Hermansky-Pudlak syndrome 6 1.165
PTGDR2 prostaglandin D2 receptor 2 1.164
TJP1 tight junction protein 1 1.163
CCR3 chemokine (C-C motif) receptor 3 1.162
TTC7A tetratricopeptide repeat domain 7A 1.162
PRKACA protein kinase, cAMP-dependent, catalytic, alpha 1.161
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta 1.16
PRKACG protein kinase, cAMP-dependent, catalytic, gamma 1.159
AQP5 aquaporin 5 1.159
CXCL11 chemokine (C-X-C motif) ligand 11 1.157
CHIA chitinase, acidic 1.157
STIM1 stromal interaction molecule 1 1.155
HARS2 histidyl-tRNA synthetase 2, mitochondrial 1.154
NOS3 nitric oxide synthase 3 (endothelial cell) 1.154
CCL22 chemokine (C-C motif) ligand 22 1.153
ORAI1 ORAI calcium release-activated calcium modulator 1 1.152
CFAP44 cilia and flagella associated protein 44 1.149
SHH sonic hedgehog 1.148
CDC42 cell division cycle 42 1.146
PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3 1.146
AREG amphiregulin 1.144
KRT7 keratin 7, type II 1.141
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase) 1.141
CCR2 chemokine (C-C motif) receptor 2 1.139
THSD4 thrombospondin, type I, domain containing 4 1.138
FAS Fas cell surface death receptor 1.137
SLC25A18 solute carrier family 25 (glutamate carrier), member 18 1.134
STAT2 signal transducer and activator of transcription 2, 113kDa 1.134
TNNI3 troponin I type 3 (cardiac) 1.134
SPN sialophorin 1.133
SCNN1A sodium channel, non voltage gated 1 alpha subunit 1.132
HLA-C major histocompatibility complex, class I, C 1.131
BCL2 B-cell CLL/lymphoma 2 1.13
APCS amyloid P component, serum 1.129
ERVW-1 endogenous retrovirus group W, member 1 1.128
SPP1 secreted phosphoprotein 1 1.128
AFP alpha-fetoprotein 1.127
TREM1 triggering receptor expressed on myeloid cells 1 1.127
MUC13 mucin 13, cell surface associated 1.126
TRPV1 transient receptor potential cation channel, subfamily V, member 1 1.122
PIH1D1 PIH1 domain containing 1 1.121
MSH5 mutS homolog 5 1.119
CCL24 chemokine (C-C motif) ligand 24 1.119
RORC RAR-related orphan receptor C 1.118
FASLG Fas ligand (TNF superfamily, member 6) 1.118
PPIG peptidylprolyl isomerase G (cyclophilin G) 1.115
CST4 cystatin S 1.115
TBL1X transducin (beta)-like 1X-linked 1.114
SMAD9 SMAD family member 9 1.114
ALDH7A1 aldehyde dehydrogenase 7 family, member A1 1.112
ARG1 arginase 1 1.111
CROCC ciliary rootlet coiled-coil, rootletin 1.111
SST somatostatin 1.11
CLCA4 chloride channel accessory 4 1.109
FGF2 fibroblast growth factor 2 (basic) 1.108
CLCA2 chloride channel accessory 2 1.108
CORO1A coronin, actin binding protein, 1A 1.108
CD276 CD276 molecule 1.108
NAPSA napsin A aspartic peptidase 1.107
ERV3-1 endogenous retrovirus group 3, member 1 1.104
CFC1 cripto, FRL-1, cryptic family 1 1.103
OSM oncostatin M 1.103
DUOX2 dual oxidase 2 1.102
IKZF1 IKAROS family zinc finger 1 (Ikaros) 1.101
GATA3 GATA binding protein 3 1.101
VWF von Willebrand factor 1.101
CELA3B chymotrypsin-like elastase family, member 3B 1.1
TNFRSF10A tumor necrosis factor receptor superfamily, member 10a 1.1
SYK spleen tyrosine kinase 1.1
FCN1 ficolin (collagen/fibrinogen domain containing) 1 1.098
APIP APAF1 interacting protein 1.097
TIMP2 TIMP metallopeptidase inhibitor 2 1.094
ERVFRD-1 endogenous retrovirus group FRD, member 1 1.093
PPARG peroxisome proliferator-activated receptor gamma 1.092
IFNL1 interferon, lambda 1 1.092
CCL7 chemokine (C-C motif) ligand 7 1.091
CCDC185 coiled-coil domain containing 185 1.089
IREB2 iron-responsive element binding protein 2 1.089
CALML5 calmodulin-like 5 1.088
CTSB cathepsin B 1.085
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 1.083
STAT5A signal transducer and activator of transcription 5A 1.083
IL6ST interleukin 6 signal transducer 1.083
CALML4 calmodulin-like 4 1.081
STING1 stimulator of interferon response cGAMP interactor 1 1.081
CALML6 calmodulin-like 6 1.081
CALM3 calmodulin 3 (phosphorylase kinase, delta) 1.079
CALML3 calmodulin-like 3 1.078
CD44 CD44 molecule (Indian blood group) 1.077
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 1.075
CMA1 chymase 1, mast cell 1.075
BCL10 B-cell CLL/lymphoma 10 1.075
S100A12 S100 calcium binding protein A12 1.073
NKRF NFKB repressing factor 1.073
CCL13 chemokine (C-C motif) ligand 13 1.071
IRF2BP2 interferon regulatory factor 2 binding protein 2 1.071
FBLN5 fibulin 5 1.069
MARCKS myristoylated alanine-rich protein kinase C substrate 1.067
UNC13D unc-13 homolog D (C. elegans) 1.066
CBY1 chibby homolog 1 (Drosophila) 1.065
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) 1.064
NCF2 neutrophil cytosolic factor 2 1.064
LTB4R leukotriene B4 receptor 1.063
RAB27A RAB27A, member RAS oncogene family 1.063
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit 1.061
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 1.06
MALL mal, T-cell differentiation protein-like 1.059
PTEN phosphatase and tensin homolog 1.059
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13 1.058
EDNRA endothelin receptor type A 1.058
SPPL2C signal peptide peptidase like 2C 1.053
SLC26A3 solute carrier family 26 (anion exchanger), member 3 1.049
IRAK1 interleukin-1 receptor-associated kinase 1 1.049
C5AR1 complement component 5a receptor 1 1.046
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase 1.046
ENO1 enolase 1, (alpha) 1.045
GPX2 glutathione peroxidase 2 1.045
TGM2 transglutaminase 2 1.044
CKAP2 cytoskeleton associated protein 2 1.044
BLNK B-cell linker 1.044
PNP purine nucleoside phosphorylase 1.041
RABIF RAB interacting factor 1.04
SCARB1 scavenger receptor class B, member 1 1.039
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64) 1.039
CD52 CD52 molecule 1.038
FBL fibrillarin 1.037
JAGN1 jagunal homolog 1 (Drosophila) 1.036
GPX3 glutathione peroxidase 3 1.036
SCNN1D sodium channel, non voltage gated 1 delta subunit 1.033
AS3MT arsenite methyltransferase 1.032
CP ceruloplasmin (ferroxidase) 1.031
NBN nibrin 1.03
TTC29 tetratricopeptide repeat domain 29 1.03
CCP110 centriolar coiled coil protein 110kDa 1.029
S100A8 S100 calcium binding protein A8 1.029
TLR8 toll-like receptor 8 1.029
DNAH12 dynein, axonemal, heavy chain 12 1.028
CD2 CD2 molecule 1.027
STXBP2 syntaxin binding protein 2 1.027
DPP4 dipeptidyl-peptidase 4 1.027
IFNAR2 interferon (alpha, beta and omega) receptor 2 1.026
BORA bora, aurora kinase A activator 1.025
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32) 1.025
CSF3R colony stimulating factor 3 receptor (granulocyte) 1.025
MYH14 myosin, heavy chain 14, non-muscle 1.025
TCTE1 t-complex-associated-testis-expressed 1 1.024
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated) 1.024
NPHP3 nephronophthisis 3 (adolescent) 1.023
LTA4H leukotriene A4 hydrolase 1.023
PADI3 peptidyl arginine deiminase, type III 1.022
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 1.021
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 1.021
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase 1.019
HGF hepatocyte growth factor (hepapoietin A; scatter factor) 1.019
H3C12 H3 clustered histone 12 1.019
GNLY granulysin 1.018
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic) 1.018
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 1.018
MMP14 matrix metallopeptidase 14 (membrane-inserted) 1.017
DNAH14 dynein, axonemal, heavy chain 14 1.016
CEP290 centrosomal protein 290kDa 1.015
PDPN podoplanin 1.012
ADA2 adenosine deaminase 2 1.012
CD36 CD36 molecule (thrombospondin receptor) 1.012
IRF7 interferon regulatory factor 7 1.01
KRT8 keratin 8, type II 1.009
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 1.008
KLK15 kallikrein-related peptidase 15 1.008
TBX4 T-box 4 1.007
H3-5 H3.5 histone 1.007
H3C13 H3 clustered histone 13 1.007
TTLL11 tubulin tyrosine ligase-like family member 11 1.007
H3-4 H3.4 histone, cluster member 1.006
TRPA1 transient receptor potential cation channel, subfamily A, member 1 1.006
SCARB2 scavenger receptor class B, member 2 1.006
IGLL1 immunoglobulin lambda-like polypeptide 1 1.006
GPX6 glutathione peroxidase 6 1.004
EPRS1 glutamyl-prolyl-tRNA synthetase 1 1.003
GPX8 glutathione peroxidase 8 (putative) 1.003
GPX5 glutathione peroxidase 5 1.003
TRPV4 transient receptor potential cation channel, subfamily V, member 4 1.003
GPX7 glutathione peroxidase 7 1.0
TEKT2 tektin 2 (testicular) 1.0