Bronchiolitis Obliterans Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description A obstructive lung disease involving obstruction of the bronchioles due to inflammation and fibrosis which occurs as a complication of various lung conditions or physiological insults. (Human Disease Ontology, DOID_2799)
External Link https://www.disgenet.org/browser/0/1/0/C0006272
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Genes

88 genes associated with the disease Bronchiolitis Obliterans in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ACE angiotensin I converting enzyme
ANLN anillin, actin binding protein
BCL6 B-cell CLL/lymphoma 6
BDNF brain-derived neurotrophic factor
BMP4 bone morphogenetic protein 4
BMP7 bone morphogenetic protein 7
C5AR1 complement component 5a receptor 1
CABIN1 calcineurin binding protein 1
CALB2 calbindin 2
CAMP cathelicidin antimicrobial peptide
CCL2 chemokine (C-C motif) ligand 2
CCL5 chemokine (C-C motif) ligand 5
CCL7 chemokine (C-C motif) ligand 7
CCR2 chemokine (C-C motif) receptor 2
CD274 CD274 molecule
CD28 CD28 molecule
CD40LG CD40 ligand
CD59 CD59 molecule, complement regulatory protein
CD86 CD86 molecule
CDCA8 cell division cycle associated 8
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CSF1 colony stimulating factor 1 (macrophage)
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL8 chemokine (C-X-C motif) ligand 8
CXCL9 chemokine (C-X-C motif) ligand 9
CXCR3 chemokine (C-X-C motif) receptor 3
CXCR4 chemokine (C-X-C motif) receptor 4
DEFB4A defensin, beta 4A
DPP4 dipeptidyl-peptidase 4
DSG2 desmoglein 2
EGFR epidermal growth factor receptor
ELANE elastase, neutrophil expressed
ELN elastin
EYA1 EYA transcriptional coactivator and phosphatase 1
GOSR2 golgi SNAP receptor complex member 2
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HLA-A major histocompatibility complex, class I, A
HMGB1 high mobility group box 1
ICAM1 intercellular adhesion molecule 1
IFNG interferon, gamma
IL10 interleukin 10
IL13 interleukin 13
IL17A interleukin 17A
IL2 interleukin 2
IL23A interleukin 23, alpha subunit p19
IL26 interleukin 26
IL4 interleukin 4
IL6 interleukin 6
KIR2DS5 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 5
KLRC4-KLRK1 KLRC4-KLRK1 readthrough
KLRK1 killer cell lectin-like receptor subfamily K, member 1
LCN1 lipocalin 1
LTB4R leukotriene B4 receptor
MBL2 mannose-binding lectin (protein C) 2, soluble
MCAM melanoma cell adhesion molecule
MMP7 matrix metallopeptidase 7
MMP8 matrix metallopeptidase 8
MMP9 matrix metallopeptidase 9
MUC1 mucin 1, cell surface associated
NOD2 nucleotide-binding oligomerization domain containing 2
NOS3 nitric oxide synthase 3 (endothelial cell)
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NSMCE3 NSE3 homolog, SMC5-SMC6 complex component
NUDT6 nudix (nucleoside diphosphate linked moiety X)-type motif 6
PDC phosducin
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PRDX2 peroxiredoxin 2
RAG1 recombination activating gene 1
ROCK2 Rho-associated, coiled-coil containing protein kinase 2
SELE selectin E
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SFTPA1 surfactant protein A1
SFTPD surfactant protein D
SIX1 SIX homeobox 1
SIX5 SIX homeobox 5
SOCS3 suppressor of cytokine signaling 3
TGFB1 transforming growth factor, beta 1
TIMP1 TIMP metallopeptidase inhibitor 1
TLR4 toll-like receptor 4
TNF tumor necrosis factor
TNFRSF8 tumor necrosis factor receptor superfamily, member 8
VCAN versican
VEGFA vascular endothelial growth factor A