Brucellosis Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description A primary bacterial infectious disease that is caused by the bacteria of the genus Brucella, when humans come in contact with contaminated animals or animal products or ingestion of infected food products. The disease has_symptom fever, has_symptom sweat, has_symptom headache, has_symptom back pain, has_symptom physical weakness, has_symptom joint pain and has_symptom fatigue. (Human Disease Ontology, DOID_11077)
External Link https://www.disgenet.org/browser/0/1/0/C0006309
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Genes

85 genes associated with the disease Brucellosis in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ACTB actin, beta
AIM2 absent in melanoma 2
ATN1 atrophin 1
BLZF1 basic leucine zipper nuclear factor 1
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CD14 CD14 molecule
CD86 CD86 molecule
CHDH choline dehydrogenase
COMP cartilage oligomeric matrix protein
CPQ carboxypeptidase Q
CRP C-reactive protein, pentraxin-related
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CYLD cylindromatosis (turban tumor syndrome)
EBI3 Epstein-Barr virus induced 3
GIF gastric intrinsic factor (vitamin B synthesis)
GLA galactosidase, alpha
GORASP1 golgi reassembly stacking protein 1, 65kDa
GPT glutamic-pyruvate transaminase (alanine aminotransferase)
HAMP hepcidin antimicrobial peptide
HLA-B major histocompatibility complex, class I, B
IFNA1 interferon, alpha 1
IFNA13 interferon, alpha 13
IFNG interferon, gamma
IGFALS insulin-like growth factor binding protein, acid labile subunit
IL10 interleukin 10
IL12B interleukin 12B
IL13 interleukin 13
IL15 interleukin 15
IL17A interleukin 17A
IL18 interleukin 18
IL18R1 interleukin 18 receptor 1
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL1RN interleukin 1 receptor antagonist
IL2 interleukin 2
IL4 interleukin 4
IL6 interleukin 6
IRF3 interferon regulatory factor 3
KALRN kalirin, RhoGEF kinase
LAMP3 lysosomal-associated membrane protein 3
LCN2 lipocalin 2
LSAMP limbic system-associated membrane protein
LTA lymphotoxin alpha
MDH2 malate dehydrogenase 2, NAD (mitochondrial)
MEFV Mediterranean fever
MICA MHC class I polypeptide-related sequence A
MUL1 mitochondrial E3 ubiquitin protein ligase 1
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
NLRP3 NLR family, pyrin domain containing 3
NOS2 nitric oxide synthase 2, inducible
NPC1 Niemann-Pick disease, type C1
P3H3 prolyl 3-hydroxylase 3
PARK2 parkin RBR E3 ubiquitin protein ligase
PDE4A phosphodiesterase 4A, cAMP-specific
PDLIM7 PDZ and LIM domain 7 (enigma)
PRDX5 peroxiredoxin 5
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
RAB5A RAB5A, member RAS oncogene family
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
REV1 REV1, polymerase (DNA directed)
RPL12 ribosomal protein L12
RPL7 ribosomal protein L7
RSL1D1 ribosomal L1 domain containing 1
SELE selectin E
SELL selectin L
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2
SLN sarcolipin
SMN1 survival of motor neuron 1, telomeric
SMN2 survival of motor neuron 2, centromeric
SOAT1 sterol O-acyltransferase 1
SOD1 superoxide dismutase 1, soluble
SYNJ2BP synaptojanin 2 binding protein
SYT1 synaptotagmin I
TGFB1 transforming growth factor, beta 1
TLR4 toll-like receptor 4
TNF tumor necrosis factor
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TNMD tenomodulin
TNNI3 troponin I type 3 (cardiac)
VDAC1 voltage-dependent anion channel 1
VSIR V-set immunoregulatory receptor
WNK1 WNK lysine deficient protein kinase 1
ZNF645 zinc finger protein 645