Brugada Syndrome Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description A heart conduction disease that is characterized by abnormal electrocardiogram (ECG) findings and an increased risk of sudden cardiac death. (Human Disease Ontology, DOID_0050451)
External Link https://www.disgenet.org/browser/0/1/0/C1142166
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Genes

64 genes associated with the disease Brugada Syndrome in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ABCC9 ATP-binding cassette, sub-family C (CFTR/MRP), member 9
AKAP9 A kinase (PRKA) anchor protein 9
ANK2 ankyrin 2, neuronal
APRT adenine phosphoribosyltransferase
ATN1 atrophin 1
ATXN2 ataxin 2
BHLHE40 basic helix-loop-helix family, member e40
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit
CACNA2D1 calcium channel, voltage-dependent, alpha 2/delta subunit 1
CACNB2 calcium channel, voltage-dependent, beta 2 subunit
CALM2 calmodulin 2 (phosphorylase kinase, delta)
DSG2 desmoglein 2
DSP desmoplakin
EGR3 early growth response 3
ELOA elongin A
ELOB elongin B
ELOC elongin C
EPHA3 EPH receptor A3
FGF11 fibroblast growth factor 11
FGF12 fibroblast growth factor 12
FGF14 fibroblast growth factor 14
GJA1 gap junction protein, alpha 1, 43kDa
GPD1L glycerol-3-phosphate dehydrogenase 1-like
HARS1 histidyl-tRNA synthetase 1
HCN4 hyperpolarization activated cyclic nucleotide gated potassium channel 4
HEY2 hes-related family bHLH transcription factor with YRPW motif 2
HGS hepatocyte growth factor-regulated tyrosine kinase substrate
IDS iduronate 2-sulfatase
KCNAB2 potassium channel, voltage gated subfamily A regulatory beta subunit 2
KCND2 potassium channel, voltage gated Shal related subfamily D, member 2
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3
KCNE1 potassium channel, voltage gated subfamily E regulatory beta subunit 1
KCNE2 potassium channel, voltage gated subfamily E regulatory beta subunit 2
KCNE3 potassium channel, voltage gated subfamily E regulatory beta subunit 3
KCNE5 potassium channel, voltage gated subfamily E regulatory beta subunit 5
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KCNJ8 potassium channel, inwardly rectifying subfamily J, member 8
KCNK1 potassium channel, two pore domain subfamily K, member 1
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1
LRRC10 leucine rich repeat containing 10
MFAP1 microfibrillar-associated protein 1
MYH7 myosin, heavy chain 7, cardiac muscle, beta
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein
NR4A3 nuclear receptor subfamily 4, group A, member 3
PKP2 plakophilin 2
RANGRF RAN guanine nucleotide release factor
RRAD Ras-related associated with diabetes
RYR2 ryanodine receptor 2 (cardiac)
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SCN10A sodium channel, voltage gated, type X alpha subunit
SCN1B sodium channel, voltage gated, type I beta subunit
SCN2B sodium channel, voltage gated, type II beta subunit
SCN3B sodium channel, voltage gated, type III beta subunit
SCN4A sodium channel, voltage gated, type IV alpha subunit
SCN4B sodium channel, voltage gated, type IV beta subunit
SCN5A sodium channel, voltage gated, type V alpha subunit
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
SKP1 S-phase kinase-associated protein 1
SLMAP sarcolemma associated protein
SRSF5 serine/arginine-rich splicing factor 5
TBX5 T-box 5
TRPM4 transient receptor potential cation channel, subfamily M, member 4
VCL vinculin
XIRP1 xin actin binding repeat containing 1