| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Budesonide perturbation in HepG2/C3A cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Budesonide_HepG2/C3A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.392915 |
| C3 | complement component 3 | 0.175502 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.134475 |
| IGF2 | insulin-like growth factor 2 | 0.119012 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0942901 |
| MT2A | metallothionein 2A | 0.0900771 |
| GPC6 | glypican 6 | 0.0856624 |
| FN1 | fibronectin 1 | 0.07563 |
| APOB | apolipoprotein B | 0.0734707 |
| FKBP5 | FK506 binding protein 5 | 0.0672152 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0627888 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.060882 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0588857 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0557954 |
| TNS1 | tensin 1 | 0.0535133 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0484877 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | 0.0467755 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0444194 |
| GPAM | glycerol-3-phosphate acyltransferase, mitochondrial | 0.0427748 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0413774 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0408055 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0391226 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0391195 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0386666 |
| RPL37A | ribosomal protein L37a | 0.0369567 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0364474 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.035902 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | 0.0344688 |
| SMAD3 | SMAD family member 3 | 0.0337383 |
| FGA | fibrinogen alpha chain | 0.0334612 |
| PRELID2 | PRELI domain containing 2 | 0.0329708 |
| RPS12 | ribosomal protein S12 | 0.0323262 |
| PDGFC | platelet derived growth factor C | 0.0321749 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | 0.0318109 |
| FERMT2 | fermitin family member 2 | 0.0314526 |
| CRLS1 | cardiolipin synthase 1 | 0.0310633 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0309486 |
| FLNA | filamin A, alpha | 0.0302979 |
| IL4R | interleukin 4 receptor | 0.0287491 |
| POTEF | POTE ankyrin domain family, member F | 0.0286216 |
| IQSEC1 | IQ motif and Sec7 domain 1 | 0.02772 |
| LAMB1 | laminin, beta 1 | 0.0271518 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0261833 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0258371 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0257369 |
| TGM2 | transglutaminase 2 | 0.025714 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 | 0.0252757 |
| BRD4 | bromodomain containing 4 | 0.0248174 |
| ABTB3 | ankyrin repeat and BTB domain containing 3 | 0.0247116 |
| ZNF292 | zinc finger protein 292 | 0.0247012 |
| GSE1 | Gse1 coiled-coil protein | 0.0244633 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0244292 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0237295 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.022916 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | 0.0226948 |
| MRTFA | myocardin related transcription factor A | 0.0226145 |
| IFNGR1 | interferon gamma receptor 1 | 0.0222239 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0221257 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0220258 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.0218529 |
| CABIN1 | calcineurin binding protein 1 | 0.0217594 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0215823 |
| BCL2L1 | BCL2-like 1 | 0.0215497 |
| CAPZB | capping protein (actin filament) muscle Z-line, beta | 0.0214614 |
| VCL | vinculin | 0.0213597 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0213051 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0212113 |
| MED13L | mediator complex subunit 13-like | 0.0211342 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0210246 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | 0.0207533 |
| DNAH5 | dynein, axonemal, heavy chain 5 | 0.0206383 |
| RPS17 | ribosomal protein S17 | 0.0206052 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.0204078 |
| TOP1 | topoisomerase (DNA) I | 0.0198822 |
| USP47 | ubiquitin specific peptidase 47 | 0.0196685 |
| VIL1 | villin 1 | 0.0196152 |
| KDM4B | lysine (K)-specific demethylase 4B | 0.019575 |
| DIAPH1 | diaphanous-related formin 1 | 0.019522 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0194884 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0194247 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0190284 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0189233 |
| LPIN2 | lipin 2 | 0.0188835 |
| PCSK6 | proprotein convertase subtilisin/kexin type 6 | 0.0188664 |
| ALPK2 | alpha-kinase 2 | 0.018768 |
| ARHGAP9 | Rho GTPase activating protein 9 | 0.0187273 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0184685 |
| PAWR | PRKC, apoptosis, WT1, regulator | 0.0181744 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.018121 |
| FHIT | fragile histidine triad | 0.0180283 |
| FOXO3 | forkhead box O3 | 0.0180117 |
| AGRN | agrin | 0.0177152 |
| HPCAL1 | hippocalcin-like 1 | 0.0176522 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0175404 |
| CHKA | choline kinase alpha | 0.0174263 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.0173368 |
| A1CF | APOBEC1 complementation factor | 0.0173097 |
| MBNL3 | muscleblind-like splicing regulator 3 | 0.0172732 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0169198 |
| SH3BP4 | SH3-domain binding protein 4 | 0.0167795 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FBF1 | Fas (TNFRSF6) binding factor 1 | -0.192391 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.112488 |
| EHBP1 | EH domain binding protein 1 | -0.103181 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.10048 |
| PEG3 | paternally expressed 3 | -0.0961533 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0931226 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.087403 |
| TMEM123 | transmembrane protein 123 | -0.0824613 |
| EML4 | echinoderm microtubule associated protein like 4 | -0.0780181 |
| TRIM26 | tripartite motif containing 26 | -0.0763763 |
| DST | dystonin | -0.0743122 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0738583 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0723023 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0721362 |
| FRMD5 | FERM domain containing 5 | -0.0718367 |
| GPC3 | glypican 3 | -0.0716534 |
| CP | ceruloplasmin (ferroxidase) | -0.0669199 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0652333 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0606477 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0597009 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0588027 |
| DSPP | dentin sialophosphoprotein | -0.0583101 |
| ENO1 | enolase 1, (alpha) | -0.0543275 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0534125 |
| SESTD1 | SEC14 and spectrin domains 1 | -0.0532507 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0514722 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0503569 |
| ITIH2 | inter-alpha-trypsin inhibitor heavy chain 2 | -0.0488068 |
| SLC38A1 | solute carrier family 38, member 1 | -0.048171 |
| OSBPL10 | oxysterol binding protein-like 10 | -0.0480689 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0476034 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0474921 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0469385 |
| FARP1 | FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) | -0.0468509 |
| CANX | calnexin | -0.0464623 |
| LYZ | lysozyme | -0.0455671 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0454581 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0443999 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0441035 |
| RPS6 | ribosomal protein S6 | -0.0439644 |
| AHSG | alpha-2-HS-glycoprotein | -0.0433687 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0430802 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0418636 |
| VPS54 | vacuolar protein sorting 54 homolog (S. cerevisiae) | -0.0412544 |
| CNKSR3 | CNKSR family member 3 | -0.0409414 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.0403752 |
| CPE | carboxypeptidase E | -0.0399031 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0394807 |
| CFB | complement factor B | -0.0384678 |
| NHSL1 | NHS-like 1 | -0.0377532 |
| TXNRD1 | thioredoxin reductase 1 | -0.0376969 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0374693 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0372949 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0372624 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0370009 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | -0.0368261 |
| KIF5B | kinesin family member 5B | -0.0367036 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | -0.0366269 |
| SDC4 | syndecan 4 | -0.0360287 |
| B2M | beta-2-microglobulin | -0.0355323 |
| RASGRF2 | Ras protein-specific guanine nucleotide-releasing factor 2 | -0.0354431 |
| JMJD1C | jumonji domain containing 1C | -0.0351101 |
| APOE | apolipoprotein E | -0.0346111 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0344222 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0344131 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.034259 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0341903 |
| IER3 | immediate early response 3 | -0.0341805 |
| RPS27A | ribosomal protein S27a | -0.0339405 |
| FTL | ferritin, light polypeptide | -0.0338784 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0338537 |
| TPM4 | tropomyosin 4 | -0.033778 |
| PERP | PERP, TP53 apoptosis effector | -0.0334591 |
| SELENOP | selenoprotein P | -0.0333182 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0330684 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | -0.03277 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0321092 |
| AMBP | alpha-1-microglobulin/bikunin precursor | -0.0319759 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0317991 |
| RNF213 | ring finger protein 213 | -0.0317545 |
| PEG10 | paternally expressed 10 | -0.0315937 |
| UTRN | utrophin | -0.0313753 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0312611 |
| GNAS | GNAS complex locus | -0.031234 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.0307442 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0305192 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | -0.0304628 |
| ARHGAP18 | Rho GTPase activating protein 18 | -0.0303927 |
| PARD3 | par-3 family cell polarity regulator | -0.0301086 |
| GK | glycerol kinase | -0.0300781 |
| PDGFB | platelet-derived growth factor beta polypeptide | -0.0300041 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0299708 |
| RBM39 | RNA binding motif protein 39 | -0.02962 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0292038 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0286428 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | -0.0284565 |
| RPS24 | ribosomal protein S24 | -0.0283755 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0280255 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0279554 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.027571 |
