Budesonide_NCI-H460 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Budesonide perturbation in NCI-H460 cell line (Tahoe Therapeutics)
Similar Terms
Downloads & Tools

Genes

200 genes differentially expressed following the Budesonide_NCI-H460 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
PDE4D phosphodiesterase 4D, cAMP-specific 0.310205
PDE10A phosphodiesterase 10A 0.194546
PM20D1 peptidase M20 domain containing 1 0.188809
NALF1 NALCN channel auxiliary factor 1 0.16392
SLC39A8 solute carrier family 39 (zinc transporter), member 8 0.15427
SRGN serglycin 0.151477
GDA guanine deaminase 0.151444
SMYD3 SET and MYND domain containing 3 0.101025
GAPDH glyceraldehyde-3-phosphate dehydrogenase 0.0985784
TMSB10 thymosin beta 10 0.0971074
SLC7A2 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 0.0900568
MT2A metallothionein 2A 0.0668514
WDFY2 WD repeat and FYVE domain containing 2 0.0644457
PTPRM protein tyrosine phosphatase, receptor type, M 0.0587241
MAML3 mastermind-like 3 (Drosophila) 0.0582701
FTH1 ferritin, heavy polypeptide 1 0.0575304
DNER delta/notch-like EGF repeat containing 0.055014
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) 0.0544233
RGS2 regulator of G-protein signaling 2 0.0542284
PCBP3 poly(rC) binding protein 3 0.0499402
RBMS3 RNA binding motif, single stranded interacting protein 3 0.0496951
SORBS2 sorbin and SH3 domain containing 2 0.0460406
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 0.0457929
RAD51B RAD51 paralog B 0.0428537
EFNA5 ephrin-A5 0.0428494
DST dystonin 0.0423707
RTN1 reticulon 1 0.0423377
MGST1 microsomal glutathione S-transferase 1 0.0417994
AGTPBP1 ATP/GTP binding protein 1 0.0412413
TGFBI transforming growth factor, beta-induced, 68kDa 0.039821
AUTS2 autism susceptibility candidate 2 0.0381394
ERGIC1 endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1 0.0376679
AKAP12 A kinase (PRKA) anchor protein 12 0.0365486
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 0.0364907
ZMYND8 zinc finger, MYND-type containing 8 0.0362513
HIPK2 homeodomain interacting protein kinase 2 0.0356505
PRKN parkin RBR E3 ubiquitin protein ligase 0.0351543
HDAC4 histone deacetylase 4 0.0348943
TMTC1 transmembrane and tetratricopeptide repeat containing 1 0.0334229
TRIO trio Rho guanine nucleotide exchange factor 0.0328527
ADGRB3 adhesion G protein-coupled receptor B3 0.0316672
TBXT T-box transcription factor T 0.0313181
S100A10 S100 calcium binding protein A10 0.0305456
PHLDB2 pleckstrin homology-like domain, family B, member 2 0.0300388
STXBP5 syntaxin binding protein 5 (tomosyn) 0.0299302
PHF20 PHD finger protein 20 0.0296655
BABAM2 BRISC and BRCA1 A complex member 2 0.0294275
ZFHX3 zinc finger homeobox 3 0.0292717
DOCK5 dedicator of cytokinesis 5 0.0291176
FKBP5 FK506 binding protein 5 0.028954
WSB1 WD repeat and SOCS box containing 1 0.02882
RPL26 ribosomal protein L26 0.028143
CAVIN2 caveolae associated protein 2 0.0279715
S100P S100 calcium binding protein P 0.0278903
GPC6 glypican 6 0.0272484
NFIA nuclear factor I/A 0.0266784
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 0.0260773
RPLP1 ribosomal protein, large, P1 0.0259112
ENOX1 ecto-NOX disulfide-thiol exchanger 1 0.0258748
AGFG1 ArfGAP with FG repeats 1 0.0258743
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast) 0.0258731
IGF1R insulin-like growth factor 1 receptor 0.0258392
NCOR2 nuclear receptor corepressor 2 0.0256659
KIAA0825 KIAA0825 0.0252594
PYGB phosphorylase, glycogen; brain 0.0250487
SRRM2 serine/arginine repetitive matrix 2 0.0248789
RPS24 ribosomal protein S24 0.0248695
ADGRG6 adhesion G protein-coupled receptor G6 0.024456
RPS8 ribosomal protein S8 0.0244331
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 0.0242551
CHL1 cell adhesion molecule L1-like 0.0238779
PER1 period circadian clock 1 0.0236058
MT1X metallothionein 1X 0.0230712
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase 0.0227649
RPS12 ribosomal protein S12 0.0226358
SDC2 syndecan 2 0.0223919
ANKRD11 ankyrin repeat domain 11 0.0222896
PID1 phosphotyrosine interaction domain containing 1 0.0218697
RPL12 ribosomal protein L12 0.021834
GLRX glutaredoxin (thioltransferase) 0.0217805
SLC26A2 solute carrier family 26 (anion exchanger), member 2 0.0213285
RPL32 ribosomal protein L32 0.0211175
OSMR oncostatin M receptor 0.0210296
MAPK4 mitogen-activated protein kinase 4 0.0209383
RPL19 ribosomal protein L19 0.0208533
ZBTB16 zinc finger and BTB domain containing 16 0.0208313
HSPA8 heat shock 70kDa protein 8 0.0207015
ACSL1 acyl-CoA synthetase long-chain family member 1 0.0204773
MKI67 marker of proliferation Ki-67 0.0204071
RPS20 ribosomal protein S20 0.0202121
NEFL neurofilament, light polypeptide 0.0199908
EEF1A1 eukaryotic translation elongation factor 1 alpha 1 0.0196302
ADGRG2 adhesion G protein-coupled receptor G2 0.0189893
RPL23 ribosomal protein L23 0.0188462
SPTBN1 spectrin, beta, non-erythrocytic 1 0.0186155
MSI2 musashi RNA-binding protein 2 0.0185444
RPL36 ribosomal protein L36 0.0185436
RPS23 ribosomal protein S23 0.0182701
RPL37A ribosomal protein L37a 0.0182207
PTGR1 prostaglandin reductase 1 0.0181389

decreased expression

Symbol Name Standardized Value
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) -0.176795
PSD3 pleckstrin and Sec7 domain containing 3 -0.110441
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -0.103404
ADAMTS6 ADAM metallopeptidase with thrombospondin type 1 motif, 6 -0.0739965
IGFBP3 insulin-like growth factor binding protein 3 -0.0729624
DOCK4 dedicator of cytokinesis 4 -0.0721579
TM4SF1 transmembrane 4 L six family member 1 -0.0701024
CXCL8 chemokine (C-X-C motif) ligand 8 -0.0668788
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4 -0.0646894
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 -0.0633962
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 -0.0621915
TFPI2 tissue factor pathway inhibitor 2 -0.0614626
MYOF myoferlin -0.0612472
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A -0.0606159
PLEKHA5 pleckstrin homology domain containing, family A member 5 -0.0538723
SCD stearoyl-CoA desaturase (delta-9-desaturase) -0.0514942
TGFBR1 transforming growth factor, beta receptor 1 -0.0488457
PDE3A phosphodiesterase 3A, cGMP-inhibited -0.0476844
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 -0.0475934
ASPH aspartate beta-hydroxylase -0.0459091
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like) -0.0430707
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) -0.0426047
STC1 stanniocalcin 1 -0.0422221
SPAG9 sperm associated antigen 9 -0.0405669
SRGAP1 SLIT-ROBO Rho GTPase activating protein 1 -0.0378068
GPRC5A G protein-coupled receptor, class C, group 5, member A -0.0372423
ITPRID2 ITPR interacting domain containing 2 -0.0361976
CD109 CD109 molecule -0.0358952
ELL2 elongation factor, RNA polymerase II, 2 -0.0341576
INHBA inhibin, beta A -0.0332179
ZC3HAV1 zinc finger CCCH-type, antiviral 1 -0.0327932
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 -0.0327692
MAP7 microtubule-associated protein 7 -0.0326913
MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase -0.0324872
S100A6 S100 calcium binding protein A6 -0.0314142
BMERB1 bMERB domain containing 1 -0.0313974
VIM vimentin -0.0297659
CD44 CD44 molecule (Indian blood group) -0.0287063
NCKAP5 NCK-associated protein 5 -0.0282764
PHLDA1 pleckstrin homology-like domain, family A, member 1 -0.0282145
PDIA3 protein disulfide isomerase family A, member 3 -0.0276903
LIMCH1 LIM and calponin homology domains 1 -0.0266403
ERO1A endoplasmic reticulum oxidoreductase 1 alpha -0.0266127
PTEN phosphatase and tensin homolog -0.0262576
COL8A1 collagen, type VIII, alpha 1 -0.0260905
DCBLD2 discoidin, CUB and LCCL domain containing 2 -0.0260536
PDE7B phosphodiesterase 7B -0.0258547
MCL1 myeloid cell leukemia 1 -0.0257716
LMAN1 lectin, mannose-binding, 1 -0.0257325
KMT2E lysine (K)-specific methyltransferase 2E -0.0257103
CTSL cathepsin L -0.0254416
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 -0.0252304
GRAMD1B GRAM domain containing 1B -0.0252286
EZR ezrin -0.0251811
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase -0.0250858
SMOC1 SPARC related modular calcium binding 1 -0.0249604
ATAD1 ATPase family, AAA domain containing 1 -0.0245112
NHS Nance-Horan syndrome (congenital cataracts and dental anomalies) -0.0244338
SH3KBP1 SH3-domain kinase binding protein 1 -0.0240119
NEK7 NIMA-related kinase 7 -0.0236571
CANX calnexin -0.02353
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 -0.0235018
SLC2A13 solute carrier family 2 (facilitated glucose transporter), member 13 -0.0234725
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) -0.023417
SAMD4A sterile alpha motif domain containing 4A -0.0230744
GRB10 growth factor receptor-bound protein 10 -0.0230233
NT5C2 5'-nucleotidase, cytosolic II -0.0225272
SOX4 SRY (sex determining region Y)-box 4 -0.022453
WARS1 tryptophanyl-tRNA synthetase 1 -0.0224339
RABGEF1 RAB guanine nucleotide exchange factor (GEF) 1 -0.0223946
PALLD palladin, cytoskeletal associated protein -0.022332
TENT5A terminal nucleotidyltransferase 5A -0.0223111
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I -0.0222036
FMNL2 formin-like 2 -0.0218991
AKT3 v-akt murine thymoma viral oncogene homolog 3 -0.0217016
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 -0.0216062
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila) -0.0214075
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 -0.021164
PDIA6 protein disulfide isomerase family A, member 6 -0.0210231
RBPJ recombination signal binding protein for immunoglobulin kappa J region -0.0209092
NAMPT nicotinamide phosphoribosyltransferase -0.0208515
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 -0.0206549
UNC5D unc-5 homolog D (C. elegans) -0.0205265
TAF1D TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa -0.0200964
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive -0.0200762
ARIH1 ariadne RBR E3 ubiquitin protein ligase 1 -0.0199373
UBA6 ubiquitin-like modifier activating enzyme 6 -0.0197062
IFIH1 interferon induced with helicase C domain 1 -0.0196801
PGM2L1 phosphoglucomutase 2-like 1 -0.0196231
CREB5 cAMP responsive element binding protein 5 -0.0195986
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 -0.0195277
AHR aryl hydrocarbon receptor -0.0194988
OXSR1 oxidative stress responsive 1 -0.0194615
NBEAL1 neurobeachin-like 1 -0.0194158
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa -0.0193378
BIRC6 baculoviral IAP repeat containing 6 -0.0192617
STARD4 StAR-related lipid transfer (START) domain containing 4 -0.0191611
COPA coatomer protein complex, subunit alpha -0.0191308
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1 -0.0190659
ABLIM1 actin binding LIM protein 1 -0.0190181