Buprenorphine Gene Set

Dataset DrugBank Drug Targets
Category physical interactions
Type drug
Description A morphinane alkaloid that is 7,8-dihydromorphine 6-O-methyl ether in which positions 6 and 14 are joined by a -CH2CH2- bridge, one of the hydrogens of the N-methyl group is substituted by cyclopropyl, and a hydrogen at position 7 is substituted by a 2-hydroxy-3,3-dimethylbutan-2-yl group. (Chemical Entities of Biological Interest Ontology, CHEBI_3216)
External Link http://www.drugbank.ca/drugs/DB00921
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Genes

10 interacting proteins for the Buprenorphine drug from the curated DrugBank Drug Targets dataset.

Symbol Name
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
CYP2C18 cytochrome P450, family 2, subfamily C, polypeptide 18
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
CYP3A7 cytochrome P450, family 3, subfamily A, polypeptide 7
OPRD1 opioid receptor, delta 1
OPRK1 opioid receptor, kappa 1
OPRM1 opioid receptor, mu 1
UGT1A9 UDP glucuronosyltransferase 1 family, polypeptide A9