| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Busulfan perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Busulfan_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.152001 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.122549 |
| LOX | lysyl oxidase | 0.107511 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0987981 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0969645 |
| COL8A1 | collagen, type VIII, alpha 1 | 0.0792692 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0787661 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.0649062 |
| MYADM | myeloid-associated differentiation marker | 0.0561482 |
| DST | dystonin | 0.0552976 |
| MAP1B | microtubule-associated protein 1B | 0.0526826 |
| TPM4 | tropomyosin 4 | 0.0513196 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0502574 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0493124 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.045314 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0437412 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0412001 |
| CSTB | cystatin B (stefin B) | 0.0404937 |
| GOLGA4 | golgin A4 | 0.0401324 |
| VEGFC | vascular endothelial growth factor C | 0.0399493 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | 0.0376655 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0372769 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0369924 |
| MEIS2 | Meis homeobox 2 | 0.0361679 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0354083 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0351115 |
| NDRG1 | N-myc downstream regulated 1 | 0.035016 |
| NBEAL1 | neurobeachin-like 1 | 0.0348128 |
| COL1A2 | collagen, type I, alpha 2 | 0.0345198 |
| FBN1 | fibrillin 1 | 0.0343674 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0339149 |
| EHBP1 | EH domain binding protein 1 | 0.0337584 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | 0.0333723 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0329438 |
| MRPS6 | mitochondrial ribosomal protein S6 | 0.0325311 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0324061 |
| COPB1 | coatomer protein complex, subunit beta 1 | 0.0323018 |
| FRMD5 | FERM domain containing 5 | 0.0321815 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.031944 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0315677 |
| FNDC3A | fibronectin type III domain containing 3A | 0.031214 |
| SUCNR1 | succinate receptor 1 | 0.0293971 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0287035 |
| JAZF1 | JAZF zinc finger 1 | 0.0282254 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0280094 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0275503 |
| TAOK1 | TAO kinase 1 | 0.0274044 |
| LOXL2 | lysyl oxidase-like 2 | 0.0272016 |
| EXOC6B | exocyst complex component 6B | 0.0270574 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0269602 |
| INSIG1 | insulin induced gene 1 | 0.0267193 |
| MX2 | MX dynamin-like GTPase 2 | 0.0267186 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | 0.0264501 |
| PGK1 | phosphoglycerate kinase 1 | 0.0263163 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0259841 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0257168 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0257121 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.0256042 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | 0.024949 |
| VDAC1 | voltage-dependent anion channel 1 | 0.0247421 |
| BPTF | bromodomain PHD finger transcription factor | 0.0244552 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.024094 |
| GLIS3 | GLIS family zinc finger 3 | 0.0240256 |
| LDHA | lactate dehydrogenase A | 0.0233208 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0229717 |
| CCND1 | cyclin D1 | 0.0229296 |
| NF1 | neurofibromin 1 | 0.0226187 |
| RASAL2 | RAS protein activator like 2 | 0.0220807 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0217677 |
| KIF13A | kinesin family member 13A | 0.021259 |
| SBF2 | SET binding factor 2 | 0.020995 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | 0.0208113 |
| KIF5B | kinesin family member 5B | 0.0207428 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0207096 |
| CEP350 | centrosomal protein 350kDa | 0.0205964 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0205129 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0202421 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | 0.0202309 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | 0.0202245 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0202213 |
| PRKD1 | protein kinase D1 | 0.0196347 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0194594 |
| PCGF5 | polycomb group ring finger 5 | 0.0193176 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | 0.0192759 |
| FRMD4A | FERM domain containing 4A | 0.0190943 |
| TPST1 | tyrosylprotein sulfotransferase 1 | 0.01871 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0186542 |
| KIFAP3 | kinesin-associated protein 3 | 0.0186054 |
| EGR1 | early growth response 1 | 0.018526 |
| SYT1 | synaptotagmin I | 0.0185195 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | 0.0184504 |
| RAI14 | retinoic acid induced 14 | 0.0183652 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.0183514 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0182772 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | 0.0181845 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0181621 |
| ABI1 | abl-interactor 1 | 0.0180788 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 | 0.018072 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0178498 |
| GOLGB1 | golgin B1 | 0.0177398 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.211844 |
| MT2A | metallothionein 2A | -0.186889 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.124733 |
| COL5A1 | collagen, type V, alpha 1 | -0.124484 |
| UBC | ubiquitin C | -0.118296 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.109873 |
| PTMA | prothymosin, alpha | -0.0841592 |
| COL3A1 | collagen, type III, alpha 1 | -0.0818454 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0778558 |
| AHNAK | AHNAK nucleoprotein | -0.0751825 |
| CALR | calreticulin | -0.0651985 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0617769 |
| FLNA | filamin A, alpha | -0.0610625 |
| NAV2 | neuron navigator 2 | -0.0567504 |
| CD44 | CD44 molecule (Indian blood group) | -0.0490199 |
| POTEF | POTE ankyrin domain family, member F | -0.0478072 |
| RPS27A | ribosomal protein S27a | -0.0474959 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0449236 |
| RPL23 | ribosomal protein L23 | -0.0434751 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0428177 |
| PLAT | plasminogen activator, tissue | -0.0427111 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | -0.0422364 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0394918 |
| MT1X | metallothionein 1X | -0.0376024 |
| VIM | vimentin | -0.036275 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | -0.0348115 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0347 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.033767 |
| PKM | pyruvate kinase, muscle | -0.0336146 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0328751 |
| PRELID2 | PRELI domain containing 2 | -0.0328189 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | -0.032786 |
| FLNB | filamin B, beta | -0.0318763 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | -0.0314896 |
| OGA | O-GlcNAcase | -0.0309636 |
| PLEC | plectin | -0.0303973 |
| FSTL1 | follistatin-like 1 | -0.0299395 |
| B2M | beta-2-microglobulin | -0.0290689 |
| RPLP2 | ribosomal protein, large, P2 | -0.0288723 |
| ENO1 | enolase 1, (alpha) | -0.0283656 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0279667 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0279489 |
| CDH13 | cadherin 13 | -0.0277385 |
| MCL1 | myeloid cell leukemia 1 | -0.027678 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0261168 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0257272 |
| CERS2 | ceramide synthase 2 | -0.0247895 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0246658 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | -0.0246088 |
| NCOR2 | nuclear receptor corepressor 2 | -0.0245756 |
| RPL28 | ribosomal protein L28 | -0.0244176 |
| APP | amyloid beta (A4) precursor protein | -0.024195 |
| ACTN4 | actinin, alpha 4 | -0.0240827 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0239372 |
| RPL37A | ribosomal protein L37a | -0.0238627 |
| IGF2R | insulin-like growth factor 2 receptor | -0.0238372 |
| NAV1 | neuron navigator 1 | -0.023746 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -0.0234808 |
| COL5A2 | collagen, type V, alpha 2 | -0.0232527 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0232368 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | -0.0231165 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.023061 |
| RAB11FIP3 | RAB11 family interacting protein 3 (class II) | -0.0228337 |
| HLA-B | major histocompatibility complex, class I, B | -0.0228293 |
| PRKAG2 | protein kinase, AMP-activated, gamma 2 non-catalytic subunit | -0.0227654 |
| C1D | C1D nuclear receptor corepressor | -0.0222869 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0221436 |
| RPLP1 | ribosomal protein, large, P1 | -0.0221052 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0213233 |
| ASPH | aspartate beta-hydroxylase | -0.0212328 |
| LMNA | lamin A/C | -0.0211289 |
| PIEZO1 | piezo-type mechanosensitive ion channel component 1 | -0.0210991 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | -0.0210637 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | -0.0209541 |
| MSI2 | musashi RNA-binding protein 2 | -0.0209374 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0209277 |
| RPS3 | ribosomal protein S3 | -0.0208771 |
| RPL35 | ribosomal protein L35 | -0.0206238 |
| NIBAN2 | niban apoptosis regulator 2 | -0.0206223 |
| PRKCE | protein kinase C, epsilon | -0.020563 |
| HLA-C | major histocompatibility complex, class I, C | -0.0203865 |
| PFKP | phosphofructokinase, platelet | -0.0201961 |
| TNIP1 | TNFAIP3 interacting protein 1 | -0.0201741 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0200928 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0198171 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0197105 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0196234 |
| DGKG | diacylglycerol kinase, gamma 90kDa | -0.0194282 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0193917 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0192404 |
| RPS8 | ribosomal protein S8 | -0.0191834 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0191638 |
| TRABD2B | TraB domain containing 2B | -0.0189013 |
| DLGAP4 | discs, large (Drosophila) homolog-associated protein 4 | -0.018592 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0184788 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | -0.0184151 |
| COL7A1 | collagen, type VII, alpha 1 | -0.0184116 |
| SEC61G | Sec61 gamma subunit | -0.0183048 |
| DTNA | dystrobrevin, alpha | -0.0182177 |
| HS3ST3A1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 | -0.0180518 |
