| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Busulfan perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Busulfan_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VCL | vinculin | 0.153689 |
| IGF2 | insulin-like growth factor 2 | 0.137958 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0922492 |
| VIM | vimentin | 0.0654451 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0638705 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0622413 |
| PCBP2 | poly(rC) binding protein 2 | 0.0622151 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0547172 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0534108 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0528714 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0512573 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0501914 |
| DKK2 | dickkopf WNT signaling pathway inhibitor 2 | 0.0498722 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0495858 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0491609 |
| MYO1E | myosin IE | 0.047917 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.0476155 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0475296 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0473211 |
| EGR1 | early growth response 1 | 0.0471876 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0466439 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0462222 |
| MRTFA | myocardin related transcription factor A | 0.0456518 |
| TPM1 | tropomyosin 1 (alpha) | 0.0454497 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0445798 |
| DSTN | destrin (actin depolymerizing factor) | 0.043211 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0424402 |
| PCM1 | pericentriolar material 1 | 0.042219 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0420874 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0414048 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0404777 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0401626 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | 0.0398974 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | 0.0394564 |
| ERBIN | erbb2 interacting protein | 0.0386859 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0386852 |
| PRKCA | protein kinase C, alpha | 0.0382209 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0372424 |
| MCL1 | myeloid cell leukemia 1 | 0.037183 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0370619 |
| RIGI | RNA sensor RIG-I | 0.0366491 |
| SBF2 | SET binding factor 2 | 0.0353158 |
| POTEF | POTE ankyrin domain family, member F | 0.0353007 |
| RAD51B | RAD51 paralog B | 0.0351211 |
| TPM4 | tropomyosin 4 | 0.034797 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0344945 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.03434 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0342898 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.03404 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0338228 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0334144 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.032158 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0320091 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | 0.0317133 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0315425 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | 0.0314948 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0308684 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0307604 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0306209 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0301822 |
| HELZ | helicase with zinc finger | 0.0300676 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.029992 |
| DCAF6 | DDB1 and CUL4 associated factor 6 | 0.0299675 |
| ASPH | aspartate beta-hydroxylase | 0.0299625 |
| LIMA1 | LIM domain and actin binding 1 | 0.0299563 |
| CNTN4 | contactin 4 | 0.0298537 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0295359 |
| CRH | corticotropin releasing hormone | 0.0294857 |
| TOP1 | topoisomerase (DNA) I | 0.0292401 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0291962 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0290793 |
| EXOC4 | exocyst complex component 4 | 0.0288738 |
| HOMER1 | homer scaffolding protein 1 | 0.0285107 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0281867 |
| FBXO11 | F-box protein 11 | 0.0281753 |
| ANXA2 | annexin A2 | 0.028111 |
| PITPNB | phosphatidylinositol transfer protein, beta | 0.0280836 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0277906 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0277593 |
| BPTF | bromodomain PHD finger transcription factor | 0.0275006 |
| FLT1 | fms-related tyrosine kinase 1 | 0.0274128 |
| PDE10A | phosphodiesterase 10A | 0.0269906 |
| PPM1D | protein phosphatase, Mg2+/Mn2+ dependent, 1D | 0.0262668 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0261519 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0260772 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.025968 |
| RGS5 | regulator of G-protein signaling 5 | 0.0257239 |
| STXBP4 | syntaxin binding protein 4 | 0.0256534 |
| TLE4 | transducin-like enhancer of split 4 | 0.025246 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0247247 |
| CCND1 | cyclin D1 | 0.0246482 |
| PPP4R2 | protein phosphatase 4, regulatory subunit 2 | 0.0245937 |
| SETBP1 | SET binding protein 1 | 0.0244164 |
| MYOF | myoferlin | 0.0243996 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0243488 |
| GON4L | gon-4-like (C. elegans) | 0.0240842 |
| USP34 | ubiquitin specific peptidase 34 | 0.0240489 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0240307 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0239892 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | 0.023921 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | -0.156446 |
| SYT1 | synaptotagmin I | -0.0783382 |
| SCN9A | sodium channel, voltage gated, type IX alpha subunit | -0.0738729 |
| FMN1 | formin 1 | -0.0708721 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | -0.0676294 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.0625426 |
| COL1A1 | collagen, type I, alpha 1 | -0.0622545 |
| TRIB2 | tribbles pseudokinase 2 | -0.0615459 |
| PTMA | prothymosin, alpha | -0.0591348 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0588353 |
| TPST1 | tyrosylprotein sulfotransferase 1 | -0.0553546 |
| RPS24 | ribosomal protein S24 | -0.0550187 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0539775 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0501968 |
| COL3A1 | collagen, type III, alpha 1 | -0.0494682 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | -0.0491097 |
| NREP | neuronal regeneration related protein | -0.0483877 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0477762 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.0470172 |
| RPL4 | ribosomal protein L4 | -0.0467961 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | -0.0467347 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0453755 |
| HAND2 | heart and neural crest derivatives expressed 2 | -0.0438759 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0417162 |
| CADM2 | cell adhesion molecule 2 | -0.0416799 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0415544 |
| AOPEP | aminopeptidase O (putative) | -0.041249 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0405053 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0394862 |
| DDX56 | DEAD (Asp-Glu-Ala-Asp) box helicase 56 | -0.0386019 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0374837 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0372663 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0357467 |
| CD36 | CD36 molecule (thrombospondin receptor) | -0.0356419 |
| MAP1B | microtubule-associated protein 1B | -0.0350272 |
| ZFC3H1 | zinc finger, C3H1-type containing | -0.0344744 |
| FKBP10 | FK506 binding protein 10, 65 kDa | -0.0317154 |
| CCDC57 | coiled-coil domain containing 57 | -0.0313741 |
| GOLGA4 | golgin A4 | -0.031137 |
| RPL38 | ribosomal protein L38 | -0.0307254 |
| RPL23 | ribosomal protein L23 | -0.0304039 |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 | -0.0297274 |
| ATF6 | activating transcription factor 6 | -0.0296073 |
| TBX2 | T-box 2 | -0.0295607 |
| CDK6 | cyclin-dependent kinase 6 | -0.0286932 |
| HMBOX1 | homeobox containing 1 | -0.0285606 |
| YEATS2 | YEATS domain containing 2 | -0.0277509 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0274267 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0272985 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0272195 |
| RPS12 | ribosomal protein S12 | -0.0271895 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0270427 |
| SBNO1 | strawberry notch homolog 1 (Drosophila) | -0.026838 |
| DPH6 | diphthamine biosynthesis 6 | -0.0266643 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0266223 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0263395 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0262524 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0261821 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0261575 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0258505 |
| CSNK1D | casein kinase 1, delta | -0.0257837 |
| ETNK1 | ethanolamine kinase 1 | -0.0257835 |
| AHNAK | AHNAK nucleoprotein | -0.0257585 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0257155 |
| CCAR1 | cell division cycle and apoptosis regulator 1 | -0.0256163 |
| HAS2 | hyaluronan synthase 2 | -0.0255614 |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase | -0.0253998 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | -0.0252166 |
| DCAF7 | DDB1 and CUL4 associated factor 7 | -0.0248904 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0247582 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0242719 |
| UBE2D2 | ubiquitin-conjugating enzyme E2D 2 | -0.0242141 |
| RPL35A | ribosomal protein L35a | -0.0241588 |
| PHF20 | PHD finger protein 20 | -0.0241008 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0235624 |
| PHOX2B | paired-like homeobox 2b | -0.0234598 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.023416 |
| PCNP | PEST proteolytic signal containing nuclear protein | -0.0231353 |
| MEIS2 | Meis homeobox 2 | -0.0227652 |
| SH3BP5 | SH3-domain binding protein 5 (BTK-associated) | -0.022726 |
| RPS17 | ribosomal protein S17 | -0.0227013 |
| FNDC3B | fibronectin type III domain containing 3B | -0.022597 |
| RBBP6 | retinoblastoma binding protein 6 | -0.0225865 |
| XPO1 | exportin 1 | -0.0224399 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0223738 |
| C1ORF21 | chromosome 1 open reading frame 21 | -0.0222188 |
| NCAM2 | neural cell adhesion molecule 2 | -0.0220385 |
| ANGPT1 | angiopoietin 1 | -0.0218256 |
| STK17A | serine/threonine kinase 17a | -0.0218221 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0217532 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0215369 |
| PCBP3 | poly(rC) binding protein 3 | -0.0214602 |
| FRMD4A | FERM domain containing 4A | -0.0214311 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0214094 |
| UBE2O | ubiquitin-conjugating enzyme E2O | -0.0210792 |
| TUBB | tubulin, beta class I | -0.0210708 |
| TBCK | TBC1 domain containing kinase | -0.0210693 |
| AUTS2 | autism susceptibility candidate 2 | -0.0209896 |
| SEPTIN2 | septin 2 | -0.0209643 |
| NUDT3 | nudix (nucleoside diphosphate linked moiety X)-type motif 3 | -0.0208313 |
