| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Busulfan perturbation in KATO III cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Busulfan_KATO III drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.222457 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.148106 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.127177 |
| EZR | ezrin | 0.0828182 |
| ITGA6 | integrin, alpha 6 | 0.0811782 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0796067 |
| ASPH | aspartate beta-hydroxylase | 0.0795771 |
| ANXA1 | annexin A1 | 0.0784305 |
| LMO7 | LIM domain 7 | 0.071386 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0710216 |
| ENO1 | enolase 1, (alpha) | 0.0674384 |
| LCN2 | lipocalin 2 | 0.0669139 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | 0.0641679 |
| POTEF | POTE ankyrin domain family, member F | 0.059056 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0566883 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0558863 |
| PKM | pyruvate kinase, muscle | 0.052183 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0519707 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0501952 |
| AGR3 | anterior gradient 3 | 0.0494302 |
| EHBP1 | EH domain binding protein 1 | 0.0492274 |
| CDK6 | cyclin-dependent kinase 6 | 0.0467913 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0438663 |
| PCBP2 | poly(rC) binding protein 2 | 0.0429436 |
| AHR | aryl hydrocarbon receptor | 0.0426621 |
| AREG | amphiregulin | 0.0422961 |
| FAT1 | FAT atypical cadherin 1 | 0.0414397 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0396606 |
| INTS6 | integrator complex subunit 6 | 0.0387966 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0374329 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0365529 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0361979 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0361334 |
| DST | dystonin | 0.0356378 |
| SET | SET nuclear proto-oncogene | 0.0351722 |
| GDA | guanine deaminase | 0.034089 |
| TNIK | TRAF2 and NCK interacting kinase | 0.0338544 |
| PGK1 | phosphoglycerate kinase 1 | 0.0338343 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0333879 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0329193 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0328272 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0324207 |
| LIMA1 | LIM domain and actin binding 1 | 0.0322991 |
| DSTN | destrin (actin depolymerizing factor) | 0.0320982 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0318962 |
| VEGFA | vascular endothelial growth factor A | 0.0315269 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0312914 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.030869 |
| POF1B | premature ovarian failure, 1B | 0.0307788 |
| RASEF | RAS and EF-hand domain containing | 0.030583 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0304417 |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 | 0.0302611 |
| EMP1 | epithelial membrane protein 1 | 0.0300298 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0296821 |
| EGFR | epidermal growth factor receptor | 0.0296164 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0289648 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0286821 |
| DLC1 | DLC1 Rho GTPase activating protein | 0.0281384 |
| RRM2 | ribonucleotide reductase M2 | 0.027234 |
| PCM1 | pericentriolar material 1 | 0.0263884 |
| EFNB2 | ephrin-B2 | 0.0259684 |
| DYNLT3 | dynein, light chain, Tctex-type 3 | 0.0257605 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0255245 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0247221 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0246518 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0244439 |
| CENPF | centromere protein F, 350/400kDa | 0.0241809 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0239106 |
| RPS12 | ribosomal protein S12 | 0.0238902 |
| ATXN1 | ataxin 1 | 0.023665 |
| ECT2 | epithelial cell transforming 2 | 0.0236029 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0235451 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0234562 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0231007 |
| CATSPERB | catsper channel auxiliary subunit beta | 0.0230436 |
| TMOD3 | tropomodulin 3 (ubiquitous) | 0.0229455 |
| EFNA5 | ephrin-A5 | 0.0229316 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0226445 |
| TPM3 | tropomyosin 3 | 0.0224713 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | 0.0224531 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.0222669 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0222106 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0220627 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0220108 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0217614 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.021713 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0213689 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | 0.0212264 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0209738 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0208533 |
| SLTM | SAFB-like, transcription modulator | 0.0207608 |
| FAM107B | family with sequence similarity 107, member B | 0.020659 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | 0.0206195 |
| ANLN | anillin, actin binding protein | 0.0205194 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0202449 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0202246 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0202006 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0199533 |
| MYADM | myeloid-associated differentiation marker | 0.0197848 |
| TES | testin LIM domain protein | 0.0197639 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.268538 |
| FGFR2 | fibroblast growth factor receptor 2 | -0.234261 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.104092 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0925424 |
| H1-0 | H1.0 linker histone | -0.0834261 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0688832 |
| RRBP1 | ribosome binding protein 1 | -0.0661512 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0658618 |
| TMSB10 | thymosin beta 10 | -0.0638934 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0544381 |
| CD2AP | CD2-associated protein | -0.0509016 |
| PRSS3 | protease, serine, 3 | -0.0507017 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0504274 |
| PTMA | prothymosin, alpha | -0.05006 |
| HLA-C | major histocompatibility complex, class I, C | -0.0491041 |
| TMEM45B | transmembrane protein 45B | -0.0470247 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | -0.0464773 |
| HLA-E | major histocompatibility complex, class I, E | -0.0462552 |
| TMC5 | transmembrane channel-like 5 | -0.0442388 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0428767 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0425239 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0423549 |
| RBM39 | RNA binding motif protein 39 | -0.0413685 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0410872 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0405593 |
| ACTN4 | actinin, alpha 4 | -0.0397921 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.039632 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0391097 |
| MUC17 | mucin 17, cell surface associated | -0.0389005 |
| EPCAM | epithelial cell adhesion molecule | -0.0356801 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0355899 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0354052 |
| ZC3H12B | zinc finger CCCH-type containing 12B | -0.035319 |
| ANXA2 | annexin A2 | -0.0349689 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.0345683 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0345556 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0342421 |
| LLGL2 | lethal giant larvae homolog 2 (Drosophila) | -0.0336381 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.033283 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0328994 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0326581 |
| STK24 | serine/threonine kinase 24 | -0.0313109 |
| GPX2 | glutathione peroxidase 2 | -0.0313048 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | -0.0308531 |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | -0.0306355 |
| ATM | ATM serine/threonine kinase | -0.0302923 |
| PLSCR1 | phospholipid scramblase 1 | -0.0300098 |
| XAF1 | XIAP associated factor 1 | -0.0298921 |
| CALR | calreticulin | -0.0298622 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -0.0297962 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0296944 |
| NECTIN2 | nectin cell adhesion molecule 2 | -0.0295003 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | -0.029465 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0294343 |
| KLF6 | Kruppel-like factor 6 | -0.0294047 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -0.0290622 |
| SH3RF1 | SH3 domain containing ring finger 1 | -0.0289605 |
| MUC13 | mucin 13, cell surface associated | -0.0288576 |
| FDFT1 | farnesyl-diphosphate farnesyltransferase 1 | -0.0286801 |
| S100A10 | S100 calcium binding protein A10 | -0.0285657 |
| H3-3B | H3.3 histone B | -0.0281928 |
| GAK | cyclin G associated kinase | -0.0280269 |
| KLF3 | Kruppel-like factor 3 (basic) | -0.0277586 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0275983 |
| CLINT1 | clathrin interactor 1 | -0.0273287 |
| NF1 | neurofibromin 1 | -0.0270754 |
| AOPEP | aminopeptidase O (putative) | -0.0269902 |
| AVL9 | AVL9 homolog (S. cerevisiase) | -0.0269594 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0269404 |
| ACTG1 | actin gamma 1 | -0.0269214 |
| UBE4A | ubiquitination factor E4A | -0.0267754 |
| ITGB4 | integrin, beta 4 | -0.0267469 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0267148 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0266891 |
| BCL2L1 | BCL2-like 1 | -0.0266301 |
| TRIM31 | tripartite motif containing 31 | -0.026504 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0263729 |
| NFX1 | nuclear transcription factor, X-box binding 1 | -0.0263199 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0261594 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0261083 |
| RNF213 | ring finger protein 213 | -0.0260828 |
| ABHD17C | abhydrolase domain containing 17C | -0.0254765 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0252909 |
| ALDOC | aldolase C, fructose-bisphosphate | -0.025276 |
| PMM2 | phosphomannomutase 2 | -0.0252686 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | -0.025267 |
| TNRC18 | trinucleotide repeat containing 18 | -0.0251874 |
| SHB | Src homology 2 domain containing adaptor protein B | -0.0251314 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0250425 |
| RPL34 | ribosomal protein L34 | -0.0248272 |
| SHROOM3 | shroom family member 3 | -0.024261 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.0239983 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0239405 |
| GRB2 | growth factor receptor-bound protein 2 | -0.0239115 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0238205 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0237971 |
| MGAM2 | maltase-glucoamylase 2 (putative) | -0.0237589 |
| EIF4H | eukaryotic translation initiation factor 4H | -0.0237062 |
| ARF1 | ADP-ribosylation factor 1 | -0.0236287 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0233147 |
