| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Busulfan perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Busulfan_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TP63 | tumor protein p63 | 0.16236 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.107184 |
| DST | dystonin | 0.104468 |
| VCL | vinculin | 0.0923106 |
| CD44 | CD44 molecule (Indian blood group) | 0.09163 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0766479 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0745242 |
| CADM2 | cell adhesion molecule 2 | 0.0706991 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0681369 |
| HLA-B | major histocompatibility complex, class I, B | 0.0652812 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0615582 |
| RAD51B | RAD51 paralog B | 0.0585819 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0543226 |
| RIGI | RNA sensor RIG-I | 0.0535767 |
| SP100 | SP100 nuclear antigen | 0.0527944 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0523719 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0509226 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0507198 |
| PRELID2 | PRELI domain containing 2 | 0.048314 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0479957 |
| HDAC9 | histone deacetylase 9 | 0.0463771 |
| RUNX1 | runt-related transcription factor 1 | 0.044184 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0426061 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 | 0.0425242 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0383887 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0382949 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0382093 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0346874 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.0344317 |
| GNGT1 | guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 | 0.0341516 |
| CFAP299 | cilia and flagella associated protein 299 | 0.0331858 |
| DPH6 | diphthamine biosynthesis 6 | 0.0329805 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0328612 |
| RPL37A | ribosomal protein L37a | 0.0303583 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0301164 |
| TPRG1 | tumor protein p63 regulated 1 | 0.0301156 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | 0.0292038 |
| PLSCR1 | phospholipid scramblase 1 | 0.0291514 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0280721 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0280265 |
| SMYD3 | SET and MYND domain containing 3 | 0.0278613 |
| DNAH14 | dynein, axonemal, heavy chain 14 | 0.0277011 |
| EPHA4 | EPH receptor A4 | 0.0274226 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0268531 |
| HLA-E | major histocompatibility complex, class I, E | 0.025968 |
| EXOC4 | exocyst complex component 4 | 0.0256217 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | 0.0245024 |
| B2M | beta-2-microglobulin | 0.0244408 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0243039 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0240877 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0239503 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | 0.0229991 |
| CDK6 | cyclin-dependent kinase 6 | 0.0229833 |
| RPS29 | ribosomal protein S29 | 0.0228994 |
| EFNA5 | ephrin-A5 | 0.0225521 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0221542 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.0217971 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0217661 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0215774 |
| RPL35A | ribosomal protein L35a | 0.0215342 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0210403 |
| FHIT | fragile histidine triad | 0.0204692 |
| RPL38 | ribosomal protein L38 | 0.0203718 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0202587 |
| INTS6 | integrator complex subunit 6 | 0.0199651 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | 0.0195717 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0192037 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0190358 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0188789 |
| CUX1 | cut-like homeobox 1 | 0.0185473 |
| EHBP1 | EH domain binding protein 1 | 0.0183546 |
| RPS10 | ribosomal protein S10 | 0.0182114 |
| GOLGB1 | golgin B1 | 0.0182103 |
| ENO1 | enolase 1, (alpha) | 0.0177548 |
| NEK10 | NIMA-related kinase 10 | 0.0176978 |
| CCDC190 | coiled-coil domain containing 190 | 0.0174412 |
| RTTN | rotatin | 0.0172584 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0171749 |
| DTNB | dystrobrevin, beta | 0.0170907 |
| PRKCE | protein kinase C, epsilon | 0.0170418 |
| ETV6 | ets variant 6 | 0.0170403 |
| NRG1 | neuregulin 1 | 0.0170159 |
| CCDC88A | coiled-coil domain containing 88A | 0.0169929 |
| FERMT1 | fermitin family member 1 | 0.0164717 |
| TRIM55 | tripartite motif containing 55 | 0.0163401 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | 0.0162204 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0161671 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 0.0161324 |
| RPS3 | ribosomal protein S3 | 0.0156244 |
| RPL31 | ribosomal protein L31 | 0.0154992 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0153926 |
| HLA-A | major histocompatibility complex, class I, A | 0.0150838 |
| OASL | 2'-5'-oligoadenylate synthetase-like | 0.0150453 |
| NCOA2 | nuclear receptor coactivator 2 | 0.0150408 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | 0.0150265 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0149143 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | 0.0148678 |
| RNF213 | ring finger protein 213 | 0.0147287 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0147281 |
| RPL9 | ribosomal protein L9 | 0.0146653 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.156356 |
| TMSB10 | thymosin beta 10 | -0.142696 |
| VIM | vimentin | -0.123344 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.111182 |
| TXNRD1 | thioredoxin reductase 1 | -0.0936186 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0896618 |
| RAI1 | retinoic acid induced 1 | -0.0856926 |
| MT2A | metallothionein 2A | -0.0828928 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0762428 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0739406 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0722672 |
| MT1X | metallothionein 1X | -0.0661487 |
| POTEF | POTE ankyrin domain family, member F | -0.0642438 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0629743 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0623995 |
| PTMA | prothymosin, alpha | -0.0622482 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0611939 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.061178 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0599148 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | -0.0558921 |
| AHNAK | AHNAK nucleoprotein | -0.0552508 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0545334 |
| CANX | calnexin | -0.0464773 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0435062 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0425426 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0417499 |
| APP | amyloid beta (A4) precursor protein | -0.0417201 |
| EZR | ezrin | -0.0409922 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0405515 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0400692 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0393059 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0392704 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0388844 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0387642 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0383493 |
| USP34 | ubiquitin specific peptidase 34 | -0.0381237 |
| KLF6 | Kruppel-like factor 6 | -0.0379789 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0373809 |
| YEATS2 | YEATS domain containing 2 | -0.0368505 |
| TXNIP | thioredoxin interacting protein | -0.0367486 |
| FLNB | filamin B, beta | -0.0360323 |
| ADAM17 | ADAM metallopeptidase domain 17 | -0.0354246 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0351251 |
| RTN4 | reticulon 4 | -0.0349897 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0344932 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0341384 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0339634 |
| TMEM41B | transmembrane protein 41B | -0.0338644 |
| POM121 | POM121 transmembrane nucleoporin | -0.0322553 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.0318205 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0311894 |
| HMGA1 | high mobility group AT-hook 1 | -0.0311363 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0309991 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0309668 |
| RBM25 | RNA binding motif protein 25 | -0.0306355 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | -0.0304796 |
| CENPF | centromere protein F, 350/400kDa | -0.0298377 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.029669 |
| SEC24A | SEC24 family member A | -0.0291625 |
| HDLBP | high density lipoprotein binding protein | -0.0290235 |
| RAP2B | RAP2B, member of RAS oncogene family | -0.0285901 |
| CEP170 | centrosomal protein 170kDa | -0.0285739 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | -0.028478 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | -0.0284162 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0283721 |
| GSK3B | glycogen synthase kinase 3 beta | -0.027991 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | -0.0273989 |
| NUP58 | nucleoporin 58 | -0.0272007 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0271642 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | -0.0270193 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0268371 |
| SRPK2 | SRSF protein kinase 2 | -0.0265482 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0263836 |
| UBC | ubiquitin C | -0.0262437 |
| SNX14 | sorting nexin 14 | -0.0260421 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0258972 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0257901 |
| MKI67 | marker of proliferation Ki-67 | -0.0257645 |
| TMSB4X | thymosin beta 4, X-linked | -0.025652 |
| GOLGA4 | golgin A4 | -0.0255461 |
| PFN1 | profilin 1 | -0.0252123 |
| ZNF292 | zinc finger protein 292 | -0.0250408 |
| PCBP2 | poly(rC) binding protein 2 | -0.0249661 |
| SBF2 | SET binding factor 2 | -0.0248999 |
| HOOK2 | hook microtubule-tethering protein 2 | -0.0247632 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0244209 |
| CELF1 | CUGBP, Elav-like family member 1 | -0.0240118 |
| QKI | QKI, KH domain containing, RNA binding | -0.0239386 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0238585 |
| GPBP1L1 | GC-rich promoter binding protein 1-like 1 | -0.0238566 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | -0.0238423 |
| LOXL2 | lysyl oxidase-like 2 | -0.0237976 |
| RBM39 | RNA binding motif protein 39 | -0.0236882 |
| MAP4 | microtubule-associated protein 4 | -0.0235991 |
| JMJD1C | jumonji domain containing 1C | -0.0234647 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0228103 |
| RLF | rearranged L-myc fusion | -0.0227808 |
| OGA | O-GlcNAcase | -0.0227676 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | -0.0227242 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0226526 |
