| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Busulfan perturbation in NCI-H2030 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Busulfan_NCI-H2030 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.237055 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.101655 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0836565 |
| MCL1 | myeloid cell leukemia 1 | 0.0726058 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0713272 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0703891 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0671052 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0593763 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0578419 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.057464 |
| WWOX | WW domain containing oxidoreductase | 0.054708 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0544891 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.047984 |
| GRAMD1B | GRAM domain containing 1B | 0.0478469 |
| ATXN1 | ataxin 1 | 0.0468898 |
| DST | dystonin | 0.0445186 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0431173 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0409661 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.037928 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0374774 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0370584 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0359127 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0357313 |
| IL6 | interleukin 6 | 0.0340962 |
| FAM107B | family with sequence similarity 107, member B | 0.0321792 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0310554 |
| BMP6 | bone morphogenetic protein 6 | 0.0310293 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0301499 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0300576 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0296614 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0288638 |
| LAMC2 | laminin, gamma 2 | 0.0282932 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0276541 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0266621 |
| TPM3 | tropomyosin 3 | 0.0265008 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0261742 |
| KIAA0319 | KIAA0319 | 0.0257564 |
| SLC35F3 | solute carrier family 35, member F3 | 0.0254131 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | 0.0248873 |
| CDCP1 | CUB domain containing protein 1 | 0.0247466 |
| GOLGB1 | golgin B1 | 0.0247075 |
| PM20D1 | peptidase M20 domain containing 1 | 0.0245453 |
| MYO1E | myosin IE | 0.0243225 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0240903 |
| POTEF | POTE ankyrin domain family, member F | 0.0239912 |
| PDE10A | phosphodiesterase 10A | 0.0239145 |
| PRKCE | protein kinase C, epsilon | 0.0236248 |
| ANGPTL4 | angiopoietin-like 4 | 0.0232056 |
| SMYD3 | SET and MYND domain containing 3 | 0.023192 |
| RSPO3 | R-spondin 3 | 0.0230966 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | 0.0229029 |
| PYGL | phosphorylase, glycogen, liver | 0.022865 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0226229 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0225467 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0222976 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0222154 |
| LDHA | lactate dehydrogenase A | 0.0218928 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0218623 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0218472 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0218108 |
| RPS2 | ribosomal protein S2 | 0.0216996 |
| TPM4 | tropomyosin 4 | 0.0214292 |
| CCPG1 | cell cycle progression 1 | 0.0214145 |
| FHIT | fragile histidine triad | 0.0213554 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0212291 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0211027 |
| TPM1 | tropomyosin 1 (alpha) | 0.0210041 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0209218 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.02081 |
| PRELID2 | PRELI domain containing 2 | 0.0207637 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.02054 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0203316 |
| PDLIM5 | PDZ and LIM domain 5 | 0.020274 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0201719 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0197834 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0195732 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.019275 |
| ITGAV | integrin, alpha V | 0.0192541 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0191255 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0189324 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | 0.018812 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0186415 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0186143 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.018609 |
| PRKD1 | protein kinase D1 | 0.0183181 |
| STC1 | stanniocalcin 1 | 0.0181529 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0180575 |
| SYAP1 | synapse associated protein 1 | 0.0177681 |
| NEBL | nebulette | 0.017733 |
| CALD1 | caldesmon 1 | 0.0177305 |
| MYOF | myoferlin | 0.017708 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0173884 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | 0.0172838 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0172662 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0168366 |
| CHD1L | chromodomain helicase DNA binding protein 1-like | 0.016687 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0165884 |
| ATP11A | ATPase, class VI, type 11A | 0.0164281 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.016222 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0161671 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.16048 |
| TXNRD1 | thioredoxin reductase 1 | -0.140929 |
| PTMA | prothymosin, alpha | -0.0988543 |
| HDAC9 | histone deacetylase 9 | -0.0823841 |
| IGF2 | insulin-like growth factor 2 | -0.0811279 |
| FTL | ferritin, light polypeptide | -0.0795104 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0719433 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -0.0701079 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0673167 |
| RBM39 | RNA binding motif protein 39 | -0.0646954 |
| WDR43 | WD repeat domain 43 | -0.0611106 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0608235 |
| RPS21 | ribosomal protein S21 | -0.0573581 |
| RPL23 | ribosomal protein L23 | -0.054953 |
| MT2A | metallothionein 2A | -0.053488 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0510578 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0497362 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0490767 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0479882 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0474975 |
| ERBIN | erbb2 interacting protein | -0.0460018 |
| CAVIN1 | caveolae associated protein 1 | -0.0454492 |
| ECT2 | epithelial cell transforming 2 | -0.0453047 |
| LMNA | lamin A/C | -0.0421401 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0420797 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.041804 |
| YBX3 | Y box binding protein 3 | -0.0414086 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0410791 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.04099 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0409842 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0403016 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0392215 |
| CYRIB | CYFIP related Rac1 interactor B | -0.0381802 |
| RPL19 | ribosomal protein L19 | -0.0372681 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0370298 |
| KHDC4 | KH domain containing 4, pre-mRNA splicing factor | -0.0365218 |
| PUM1 | pumilio RNA-binding family member 1 | -0.0357155 |
| RPL31 | ribosomal protein L31 | -0.0354891 |
| RBM25 | RNA binding motif protein 25 | -0.0343391 |
| RHEB | Ras homolog enriched in brain | -0.0340393 |
| PAWR | PRKC, apoptosis, WT1, regulator | -0.0331548 |
| ACTG1 | actin gamma 1 | -0.0328657 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0323591 |
| EWSR1 | EWS RNA-binding protein 1 | -0.0323411 |
| IER3 | immediate early response 3 | -0.0322037 |
| PTK2 | protein tyrosine kinase 2 | -0.0320393 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0317315 |
| ZNF207 | zinc finger protein 207 | -0.0313894 |
| RPL4 | ribosomal protein L4 | -0.031311 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.031058 |
| RPL35A | ribosomal protein L35a | -0.0307887 |
| USP3 | ubiquitin specific peptidase 3 | -0.0305964 |
| PFDN2 | prefoldin subunit 2 | -0.0305118 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0303635 |
| ACACA | acetyl-CoA carboxylase alpha | -0.0293895 |
| RPS27A | ribosomal protein S27a | -0.0291223 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0291217 |
| SETD5 | SET domain containing 5 | -0.0290445 |
| SERF2 | small EDRK-rich factor 2 | -0.0288499 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0287265 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0284874 |
| RHOA | ras homolog family member A | -0.028166 |
| RPS29 | ribosomal protein S29 | -0.0279256 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0278559 |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | -0.0276775 |
| BICC1 | BicC family RNA binding protein 1 | -0.0275681 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0275316 |
| RPS23 | ribosomal protein S23 | -0.0275305 |
| NOL10 | nucleolar protein 10 | -0.0267374 |
| SIK3 | SIK family kinase 3 | -0.0267362 |
| APP | amyloid beta (A4) precursor protein | -0.0265664 |
| IST1 | increased sodium tolerance 1 homolog (yeast) | -0.0264291 |
| ATXN2L | ataxin 2-like | -0.0263721 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0261363 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0260557 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | -0.0259969 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | -0.0259727 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.025949 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0258463 |
| MORF4L1 | mortality factor 4 like 1 | -0.025768 |
| TNRC6B | trinucleotide repeat containing 6B | -0.0254522 |
| SMAD2 | SMAD family member 2 | -0.0254137 |
| FUS | FUS RNA binding protein | -0.0253932 |
| ILF2 | interleukin enhancer binding factor 2 | -0.0251885 |
| TFG | TRK-fused gene | -0.0251829 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0249045 |
| NTN4 | netrin 4 | -0.0248345 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0247349 |
| FBXO11 | F-box protein 11 | -0.0245709 |
| NOP58 | NOP58 ribonucleoprotein | -0.0242938 |
| NRG1 | neuregulin 1 | -0.0241816 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0241657 |
| ASXL1 | additional sex combs like transcriptional regulator 1 | -0.0241466 |
| RASAL2 | RAS protein activator like 2 | -0.0240133 |
| UBAP2L | ubiquitin associated protein 2-like | -0.0239991 |
| FDPS | farnesyl diphosphate synthase | -0.0239979 |
| CDK12 | cyclin-dependent kinase 12 | -0.0239438 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0237942 |
| LAPTM4A | lysosomal protein transmembrane 4 alpha | -0.0237867 |
| RPL36 | ribosomal protein L36 | -0.023776 |
