| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Busulfan perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Busulfan_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.110101 |
| FN1 | fibronectin 1 | 0.0929114 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0863291 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.0834288 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0779601 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0672511 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0667184 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.0640734 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0633804 |
| CD44 | CD44 molecule (Indian blood group) | 0.0590419 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0585954 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0556907 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0519559 |
| EGFR | epidermal growth factor receptor | 0.0511531 |
| FMN1 | formin 1 | 0.0493868 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0493538 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0482754 |
| EHBP1 | EH domain binding protein 1 | 0.0480989 |
| KIF5B | kinesin family member 5B | 0.0480156 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0476825 |
| DIAPH2 | diaphanous-related formin 2 | 0.0469856 |
| COPB1 | coatomer protein complex, subunit beta 1 | 0.0435478 |
| HLA-B | major histocompatibility complex, class I, B | 0.0431705 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0431519 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0428771 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.042872 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0424871 |
| MAGI3 | membrane associated guanylate kinase, WW and PDZ domain containing 3 | 0.0423653 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0417931 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0414342 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0412335 |
| CDH13 | cadherin 13 | 0.0411066 |
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | 0.0407791 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.040707 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0406008 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0404851 |
| B2M | beta-2-microglobulin | 0.0404375 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0403595 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0401702 |
| ENO1 | enolase 1, (alpha) | 0.0399936 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0397189 |
| LSM14A | LSM14A, SCD6 homolog A (S. cerevisiae) | 0.0393535 |
| NLGN1 | neuroligin 1 | 0.0392447 |
| RAD51B | RAD51 paralog B | 0.0389607 |
| PDE10A | phosphodiesterase 10A | 0.0385805 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0384716 |
| CANX | calnexin | 0.0384461 |
| AK1 | adenylate kinase 1 | 0.0381862 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0380167 |
| ATP13A3 | ATPase type 13A3 | 0.0376411 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | 0.0373576 |
| USP25 | ubiquitin specific peptidase 25 | 0.0372531 |
| TXNRD1 | thioredoxin reductase 1 | 0.0365227 |
| IGF2 | insulin-like growth factor 2 | 0.0363837 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0360648 |
| JMJD1C | jumonji domain containing 1C | 0.0359118 |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 | 0.0358395 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0356135 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.0356134 |
| ZNF638 | zinc finger protein 638 | 0.0354014 |
| FLNB | filamin B, beta | 0.0353659 |
| RIGI | RNA sensor RIG-I | 0.034601 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0344091 |
| PEAK1 | pseudopodium-enriched atypical kinase 1 | 0.0343863 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0337603 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0334938 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0334073 |
| HMGA2 | high mobility group AT-hook 2 | 0.0330014 |
| USP33 | ubiquitin specific peptidase 33 | 0.0329231 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.0327152 |
| EFNA5 | ephrin-A5 | 0.032694 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0320809 |
| NRG3 | neuregulin 3 | 0.032022 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0318964 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0317229 |
| TNS3 | tensin 3 | 0.0314348 |
| UBE3C | ubiquitin protein ligase E3C | 0.0313715 |
| SCFD1 | sec1 family domain containing 1 | 0.0308244 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | 0.0307907 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | 0.0302983 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0302427 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0299924 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0296924 |
| SDCBP | syndecan binding protein (syntenin) | 0.0295895 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0293259 |
| RLF | rearranged L-myc fusion | 0.0292223 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0292134 |
| DST | dystonin | 0.0291562 |
| TUSC3 | tumor suppressor candidate 3 | 0.0287118 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0286058 |
| SERINC5 | serine incorporator 5 | 0.0285379 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0283442 |
| BBX | bobby sox homolog (Drosophila) | 0.0278449 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.027713 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0274306 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | 0.0274118 |
| INHBA | inhibin, beta A | 0.0272668 |
| CLIC4 | chloride intracellular channel 4 | 0.0269955 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0269811 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0268968 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.157677 |
| TMSB10 | thymosin beta 10 | -0.107432 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.104441 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0938074 |
| ANXA2 | annexin A2 | -0.091779 |
| MYO1E | myosin IE | -0.0901061 |
| NDRG1 | N-myc downstream regulated 1 | -0.0822356 |
| NCOA3 | nuclear receptor coactivator 3 | -0.0708043 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0681902 |
| KRT17 | keratin 17, type I | -0.0620148 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0614993 |
| LAMC2 | laminin, gamma 2 | -0.0591085 |
| S100A10 | S100 calcium binding protein A10 | -0.0587019 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0586142 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | -0.0574102 |
| FTL | ferritin, light polypeptide | -0.0569882 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0568821 |
| SVIL | supervillin | -0.0560977 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.0538682 |
| VMP1 | vacuole membrane protein 1 | -0.0525364 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | -0.0504377 |
| RPL23 | ribosomal protein L23 | -0.0496206 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.04929 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0492287 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0485625 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0484391 |
| ATOSA | atos homolog A | -0.0458682 |
| HELZ | helicase with zinc finger | -0.0457262 |
| MSI2 | musashi RNA-binding protein 2 | -0.045722 |
| PKM | pyruvate kinase, muscle | -0.0454168 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0419107 |
| AREG | amphiregulin | -0.0412398 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | -0.0411913 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0410046 |
| USP53 | ubiquitin specific peptidase 53 | -0.0409096 |
| TPR | translocated promoter region, nuclear basket protein | -0.0404322 |
| FGFR2 | fibroblast growth factor receptor 2 | -0.0400241 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0396543 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0393512 |
| LMO7 | LIM domain 7 | -0.0392461 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0390614 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0387288 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0382855 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0381952 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.037661 |
| RPL35A | ribosomal protein L35a | -0.0376242 |
| FBXL20 | F-box and leucine-rich repeat protein 20 | -0.0375603 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.0372891 |
| VIM | vimentin | -0.0372563 |
| MYO6 | myosin VI | -0.0368562 |
| PARD3 | par-3 family cell polarity regulator | -0.0362647 |
| LAMB3 | laminin, beta 3 | -0.035497 |
| C1GALT1 | core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 | -0.0353393 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0352359 |
| RBM39 | RNA binding motif protein 39 | -0.0350177 |
| GOLGA4 | golgin A4 | -0.0349465 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.034599 |
| ARHGAP21 | Rho GTPase activating protein 21 | -0.0344056 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | -0.0343723 |
| WASF2 | WAS protein family, member 2 | -0.0343076 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0342975 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0336968 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0336615 |
| RORA | RAR-related orphan receptor A | -0.0335512 |
| CALU | calumenin | -0.0334277 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0334015 |
| KLF6 | Kruppel-like factor 6 | -0.0333532 |
| ACTG1 | actin gamma 1 | -0.0333502 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0332708 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0329577 |
| DIAPH1 | diaphanous-related formin 1 | -0.0329002 |
| TOP1 | topoisomerase (DNA) I | -0.0322854 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.0316328 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0312315 |
| WDR45B | WD repeat domain 45B | -0.0309956 |
| JUP | junction plakoglobin | -0.0308313 |
| ANXA1 | annexin A1 | -0.030801 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0302629 |
| ANXA11 | annexin A11 | -0.029937 |
| BTRC | beta-transducin repeat containing E3 ubiquitin protein ligase | -0.029503 |
| UFM1 | ubiquitin-fold modifier 1 | -0.0293472 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.028895 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | -0.02888 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | -0.0288104 |
| SNX9 | sorting nexin 9 | -0.0285018 |
| CYTH1 | cytohesin 1 | -0.0284987 |
| TMEM41B | transmembrane protein 41B | -0.028402 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0283584 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0283431 |
| ARF1 | ADP-ribosylation factor 1 | -0.0282732 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.0281764 |
| AGFG1 | ArfGAP with FG repeats 1 | -0.0277115 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.027663 |
| POTEF | POTE ankyrin domain family, member F | -0.0275567 |
| RASA2 | RAS p21 protein activator 2 | -0.0274198 |
| UBE2B | ubiquitin-conjugating enzyme E2B | -0.0270935 |
| S100A6 | S100 calcium binding protein A6 | -0.0270529 |
| CA12 | carbonic anhydrase XII | -0.027012 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0269857 |
| MYOF | myoferlin | -0.0269294 |
