| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Busulfan perturbation in NCI-H2347 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Busulfan_NCI-H2347 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.128495 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.114292 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0601278 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0554714 |
| EFNA5 | ephrin-A5 | 0.0535696 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0518737 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0460869 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0459433 |
| INTS6 | integrator complex subunit 6 | 0.0443538 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0422707 |
| FNIP1 | folliculin interacting protein 1 | 0.0405709 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0403187 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0398792 |
| GOLGB1 | golgin B1 | 0.0393964 |
| FNDC3B | fibronectin type III domain containing 3B | 0.038997 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0388612 |
| PTK2 | protein tyrosine kinase 2 | 0.0383872 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0370618 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0359828 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0352178 |
| ERBIN | erbb2 interacting protein | 0.0346621 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0342731 |
| ATXN1 | ataxin 1 | 0.0335845 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0334542 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0331288 |
| SMAD3 | SMAD family member 3 | 0.033051 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0327785 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0316923 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.031587 |
| USP53 | ubiquitin specific peptidase 53 | 0.0308787 |
| DTNA | dystrobrevin, alpha | 0.0305598 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0298657 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0298468 |
| CTBP2 | C-terminal binding protein 2 | 0.028879 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | 0.0276904 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | 0.0274697 |
| PPP1R13B | protein phosphatase 1, regulatory subunit 13B | 0.0274031 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.027281 |
| MCL1 | myeloid cell leukemia 1 | 0.0272122 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0264985 |
| RPL9 | ribosomal protein L9 | 0.026253 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0261425 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0260754 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0260129 |
| NAV2 | neuron navigator 2 | 0.0258186 |
| DST | dystonin | 0.0253545 |
| MED13 | mediator complex subunit 13 | 0.0253078 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.025086 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0249243 |
| GOLGA4 | golgin A4 | 0.0245742 |
| RPS29 | ribosomal protein S29 | 0.0244899 |
| SCFD1 | sec1 family domain containing 1 | 0.0241723 |
| CDK13 | cyclin-dependent kinase 13 | 0.0240228 |
| BDP1 | B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB | 0.0238948 |
| MYO1E | myosin IE | 0.0238601 |
| MYOF | myoferlin | 0.023578 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0234261 |
| FLNB | filamin B, beta | 0.0230009 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0229587 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0229212 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0226263 |
| HDAC9 | histone deacetylase 9 | 0.022495 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | 0.0224041 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0221152 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0217457 |
| RPS8 | ribosomal protein S8 | 0.0215584 |
| RPS23 | ribosomal protein S23 | 0.0211114 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0210707 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0209308 |
| FBXO11 | F-box protein 11 | 0.0206113 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | 0.0206023 |
| PALLD | palladin, cytoskeletal associated protein | 0.0205253 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.0204687 |
| VCL | vinculin | 0.020451 |
| CERT1 | ceramide transporter 1 | 0.0204124 |
| RPL37A | ribosomal protein L37a | 0.0203904 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | 0.0203565 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0203322 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0203161 |
| CANX | calnexin | 0.0202869 |
| RPL5 | ribosomal protein L5 | 0.0201176 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0200636 |
| PATJ | PATJ crumbs cell polarity complex component | 0.0200413 |
| SMYD3 | SET and MYND domain containing 3 | 0.020008 |
| KIAA1217 | KIAA1217 | 0.0199982 |
| LRCH3 | leucine-rich repeats and calponin homology (CH) domain containing 3 | 0.0199059 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 | 0.0198554 |
| TJP1 | tight junction protein 1 | 0.019593 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0195188 |
| ZNF638 | zinc finger protein 638 | 0.0195083 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0194816 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0192128 |
| NUMB | numb homolog (Drosophila) | 0.0189933 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0187784 |
| CD109 | CD109 molecule | 0.0187663 |
| SQSTM1 | sequestosome 1 | 0.0186905 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0185003 |
| NABP1 | nucleic acid binding protein 1 | 0.0184972 |
| AEBP2 | AE binding protein 2 | 0.0184922 |
| PGBD5 | piggyBac transposable element derived 5 | 0.0182599 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.141695 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.131744 |
| FN1 | fibronectin 1 | -0.0870156 |
| S100A6 | S100 calcium binding protein A6 | -0.083602 |
| TMSB10 | thymosin beta 10 | -0.0799808 |
| LAMB3 | laminin, beta 3 | -0.0746245 |
| PTMA | prothymosin, alpha | -0.0732568 |
| NDRG1 | N-myc downstream regulated 1 | -0.0668302 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0654815 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0617905 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0562383 |
| MT2A | metallothionein 2A | -0.0548477 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0544179 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0535692 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0495045 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0477658 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.046588 |
| TMSB4X | thymosin beta 4, X-linked | -0.0448284 |
| PGK1 | phosphoglycerate kinase 1 | -0.0443857 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0441 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0421552 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0409833 |
| FAM162A | family with sequence similarity 162, member A | -0.0376137 |
| FAM3C | family with sequence similarity 3, member C | -0.0346913 |
| FTL | ferritin, light polypeptide | -0.034234 |
| CSTB | cystatin B (stefin B) | -0.0336683 |
| CD2AP | CD2-associated protein | -0.0334318 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0333728 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0328822 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0324541 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0319894 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.0317965 |
| LDHA | lactate dehydrogenase A | -0.0314203 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0299991 |
| H1-0 | H1.0 linker histone | -0.0293164 |
| TPI1 | triosephosphate isomerase 1 | -0.0282809 |
| SDC4 | syndecan 4 | -0.0282321 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0282188 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0281916 |
| EPCAM | epithelial cell adhesion molecule | -0.0277697 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0277394 |
| CTSB | cathepsin B | -0.0275619 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0271522 |
| TXNIP | thioredoxin interacting protein | -0.0263213 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0257209 |
| S100A10 | S100 calcium binding protein A10 | -0.0256767 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0241915 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0241055 |
| TOP1 | topoisomerase (DNA) I | -0.0238658 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0236057 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0234196 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0230447 |
| KLF6 | Kruppel-like factor 6 | -0.0217746 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.02167 |
| TMEM123 | transmembrane protein 123 | -0.0214557 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0210123 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0207628 |
| RIOK3 | RIO kinase 3 | -0.0203328 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0203231 |
| UBC | ubiquitin C | -0.0202758 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0199291 |
| G0S2 | G0/G1 switch 2 | -0.0198211 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | -0.0197694 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0197491 |
| HMGA1 | high mobility group AT-hook 1 | -0.01951 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.019495 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0190523 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0190262 |
| ASPH | aspartate beta-hydroxylase | -0.0188687 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0185506 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0178703 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0178671 |
| ACTG1 | actin gamma 1 | -0.0176863 |
| RTN4 | reticulon 4 | -0.0173667 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | -0.0172099 |
| TFG | TRK-fused gene | -0.0171771 |
| SREK1IP1 | SREK1-interacting protein 1 | -0.0169215 |
| DSG2 | desmoglein 2 | -0.0168674 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0168642 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0167424 |
| NDFIP1 | Nedd4 family interacting protein 1 | -0.016636 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.0164828 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0164501 |
| CD63 | CD63 molecule | -0.0164209 |
| RPS19 | ribosomal protein S19 | -0.0163515 |
| LAMC2 | laminin, gamma 2 | -0.0163301 |
| CHMP2B | charged multivesicular body protein 2B | -0.0160546 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0158238 |
| ADAR | adenosine deaminase, RNA-specific | -0.0157468 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -0.0157288 |
| HLA-A | major histocompatibility complex, class I, A | -0.0156216 |
| CAVIN1 | caveolae associated protein 1 | -0.015621 |
| RNF145 | ring finger protein 145 | -0.015432 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0154065 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.0151206 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | -0.0150118 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.014996 |
| HMGB2 | high mobility group box 2 | -0.0149841 |
| CDK17 | cyclin-dependent kinase 17 | -0.0149188 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.014796 |
