| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Busulfan perturbation in NCI-H596 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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197 genes differentially expressed following the Busulfan_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.13594 |
| ATXN1 | ataxin 1 | 0.125845 |
| ITGA6 | integrin, alpha 6 | 0.12272 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | 0.11857 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.115144 |
| JMJD1C | jumonji domain containing 1C | 0.115124 |
| ANXA2 | annexin A2 | 0.112408 |
| MYO10 | myosin X | 0.109624 |
| EFNA5 | ephrin-A5 | 0.108977 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.107386 |
| ETV6 | ets variant 6 | 0.10587 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | 0.103469 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.101407 |
| LMO7 | LIM domain 7 | 0.101407 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0974787 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.096609 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0883642 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0827322 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0816035 |
| PTK2 | protein tyrosine kinase 2 | 0.080687 |
| ZNF292 | zinc finger protein 292 | 0.0773931 |
| VMP1 | vacuole membrane protein 1 | 0.0731396 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0719981 |
| FMNL2 | formin-like 2 | 0.0713154 |
| USP34 | ubiquitin specific peptidase 34 | 0.0710953 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0703372 |
| CTBP2 | C-terminal binding protein 2 | 0.0700167 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0680161 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0671558 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0651193 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0620383 |
| PDE8A | phosphodiesterase 8A | 0.0588238 |
| MYO1E | myosin IE | 0.0561911 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0547629 |
| GPC6 | glypican 6 | 0.0540904 |
| NF1 | neurofibromin 1 | 0.0537117 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.053332 |
| GOLGB1 | golgin B1 | 0.0514412 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0503433 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.050062 |
| EZR | ezrin | 0.0491794 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0460919 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0452601 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0451245 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | 0.0438088 |
| GOLGA4 | golgin A4 | 0.0400966 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0397651 |
| SBF2 | SET binding factor 2 | 0.0374427 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0372971 |
| RPL11 | ribosomal protein L11 | 0.03459 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0344212 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0337593 |
| FN1 | fibronectin 1 | 0.0322597 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0273436 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0251168 |
| ACTG1 | actin gamma 1 | 0.0234964 |
| STXBP1 | syntaxin binding protein 1 | 0.0231293 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0218547 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0214408 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0192568 |
| YBX3 | Y box binding protein 3 | 0.018921 |
| RTN4 | reticulon 4 | 0.017761 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0174929 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0172022 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0171793 |
| PIAS1 | protein inhibitor of activated STAT, 1 | 0.0165626 |
| TNRC6B | trinucleotide repeat containing 6B | 0.0164165 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0158124 |
| PRKCA | protein kinase C, alpha | 0.0143125 |
| TXNIP | thioredoxin interacting protein | 0.0140725 |
| CD44 | CD44 molecule (Indian blood group) | 0.0135016 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0130331 |
| CALR | calreticulin | 0.0126562 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0122663 |
| SYP | synaptophysin | 0.0122465 |
| KIF5B | kinesin family member 5B | 0.012107 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.011161 |
| MBOAT4 | membrane bound O-acyltransferase domain containing 4 | 0.0106588 |
| MYOF | myoferlin | 0.0103849 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0102146 |
| ZC3H3 | zinc finger CCCH-type containing 3 | 0.010192 |
| SMYD3 | SET and MYND domain containing 3 | 0.00992765 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.00910777 |
| PGK1 | phosphoglycerate kinase 1 | 0.00896133 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.00881676 |
| MORF4L2 | mortality factor 4 like 2 | 0.00858013 |
| HDLBP | high density lipoprotein binding protein | 0.00756357 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.00644281 |
| NDRG1 | N-myc downstream regulated 1 | 0.00466646 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.00410393 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.00402132 |
| TXNRD1 | thioredoxin reductase 1 | 0.00333945 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.00286824 |
| DST | dystonin | 0.00210161 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.0019752 |
| CANX | calnexin | 0.00116881 |
| SAMD4A | sterile alpha motif domain containing 4A | 5.9403E-4 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.208798 |
| MT2A | metallothionein 2A | -0.159329 |
| PTMA | prothymosin, alpha | -0.130016 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.125831 |
| STC1 | stanniocalcin 1 | -0.124207 |
| RPS12 | ribosomal protein S12 | -0.123701 |
| VIM | vimentin | -0.119504 |
| PDE10A | phosphodiesterase 10A | -0.110434 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.103872 |
| MCL1 | myeloid cell leukemia 1 | -0.0991053 |
| HMGA2 | high mobility group AT-hook 2 | -0.0890659 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0885055 |
| RPL23 | ribosomal protein L23 | -0.0884959 |
| RPS19 | ribosomal protein S19 | -0.0866827 |
| LDHA | lactate dehydrogenase A | -0.084868 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0832989 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0748153 |
| TOP6BL | TOP6B like initiator of meiotic double strand breaks | -0.0702231 |
| IGF2 | insulin-like growth factor 2 | -0.069786 |
| LAMC2 | laminin, gamma 2 | -0.0686175 |
| SLTM | SAFB-like, transcription modulator | -0.0637954 |
| RPS25 | ribosomal protein S25 | -0.0636245 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0631316 |
| ENO1 | enolase 1, (alpha) | -0.0624811 |
| RPS8 | ribosomal protein S8 | -0.0623923 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0616027 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0615128 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0604814 |
| VCL | vinculin | -0.0604085 |
| COL5A1 | collagen, type V, alpha 1 | -0.0601333 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0589086 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0565296 |
| RPL37A | ribosomal protein L37a | -0.0562153 |
| RPLP2 | ribosomal protein, large, P2 | -0.0547017 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0540981 |
| LAMB3 | laminin, beta 3 | -0.0538143 |
| CDH13 | cadherin 13 | -0.0535445 |
| TMSB10 | thymosin beta 10 | -0.0534751 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0526167 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0526043 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0504128 |
| DIAPH2 | diaphanous-related formin 2 | -0.0486166 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0473719 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.0470696 |
| GRAMD1B | GRAM domain containing 1B | -0.0469703 |
| RPS6 | ribosomal protein S6 | -0.0446683 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0444633 |
| ASPH | aspartate beta-hydroxylase | -0.0438347 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0408656 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0407158 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0392146 |
| RBM39 | RNA binding motif protein 39 | -0.0391679 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0391428 |
| RPLP1 | ribosomal protein, large, P1 | -0.0379648 |
| NAV2 | neuron navigator 2 | -0.0379625 |
| RAD51B | RAD51 paralog B | -0.0372447 |
| EGFR | epidermal growth factor receptor | -0.0368119 |
| RBM25 | RNA binding motif protein 25 | -0.0355954 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0338731 |
| SLC38A1 | solute carrier family 38, member 1 | -0.033122 |
| RPL34 | ribosomal protein L34 | -0.0322014 |
| TPM4 | tropomyosin 4 | -0.0321599 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0319896 |
| PKM | pyruvate kinase, muscle | -0.0306989 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0271869 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0265751 |
| RPL31 | ribosomal protein L31 | -0.0261135 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0261041 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0253364 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0251415 |
| RPS3 | ribosomal protein S3 | -0.0241994 |
| RPL26 | ribosomal protein L26 | -0.023151 |
| HLA-B | major histocompatibility complex, class I, B | -0.0210896 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.02087 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0197126 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0195255 |
| HDAC9 | histone deacetylase 9 | -0.0191297 |
| B2M | beta-2-microglobulin | -0.0180456 |
| MAP4 | microtubule-associated protein 4 | -0.0137099 |
| NCOA3 | nuclear receptor coactivator 3 | -0.0125768 |
| POTEF | POTE ankyrin domain family, member F | -0.0117097 |
| RUNX1 | runt-related transcription factor 1 | -0.0108402 |
| FTL | ferritin, light polypeptide | -0.00969223 |
| PARD3 | par-3 family cell polarity regulator | -0.00964695 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.00956116 |
| NONO | non-POU domain containing, octamer-binding | -0.00696902 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0067168 |
| MYO6 | myosin VI | -0.00667878 |
| SPAG9 | sperm associated antigen 9 | -0.00627664 |
| DSCAM | Down syndrome cell adhesion molecule | -0.00541697 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.00535328 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0049862 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.00487352 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.00393922 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.00225452 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.00192302 |
| RPL12 | ribosomal protein L12 | -0.00176484 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.00154543 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.00119533 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -7.87173E-4 |
