| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Busulfan perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Busulfan_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.169667 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.104202 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0993697 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0953963 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0794154 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0771634 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0724076 |
| CD44 | CD44 molecule (Indian blood group) | 0.07116 |
| ASPH | aspartate beta-hydroxylase | 0.0682534 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0651224 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0632485 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0522813 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0511598 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0509886 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.05048 |
| MED13L | mediator complex subunit 13-like | 0.0489741 |
| ZNF638 | zinc finger protein 638 | 0.048402 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0469974 |
| NAV1 | neuron navigator 1 | 0.0457916 |
| RYBP | RING1 and YY1 binding protein | 0.0457372 |
| MEF2A | myocyte enhancer factor 2A | 0.0435261 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0425392 |
| ZNF292 | zinc finger protein 292 | 0.0418636 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0411047 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0406276 |
| ZNF395 | zinc finger protein 395 | 0.040332 |
| DST | dystonin | 0.0400278 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0397896 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0394115 |
| PTK2 | protein tyrosine kinase 2 | 0.0392962 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0390685 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0389477 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.0381413 |
| INSIG2 | insulin induced gene 2 | 0.0375515 |
| ENO1 | enolase 1, (alpha) | 0.0374223 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0366488 |
| IL6ST | interleukin 6 signal transducer | 0.0360177 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0358933 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0351874 |
| NDRG1 | N-myc downstream regulated 1 | 0.0349896 |
| RAD51B | RAD51 paralog B | 0.0349289 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0337557 |
| SBF2 | SET binding factor 2 | 0.0335525 |
| YAP1 | Yes-associated protein 1 | 0.0331255 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0329778 |
| ECE1 | endothelin converting enzyme 1 | 0.0329551 |
| CUX1 | cut-like homeobox 1 | 0.032905 |
| SMYD3 | SET and MYND domain containing 3 | 0.0322677 |
| KYNU | kynureninase | 0.0322027 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.031839 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0317989 |
| QKI | QKI, KH domain containing, RNA binding | 0.0311924 |
| GLIS3 | GLIS family zinc finger 3 | 0.0311056 |
| FAM13A | family with sequence similarity 13, member A | 0.0309185 |
| FAM120A | family with sequence similarity 120A | 0.0308505 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0308419 |
| SYNJ2 | synaptojanin 2 | 0.0307376 |
| CANX | calnexin | 0.0306434 |
| ARHGAP35 | Rho GTPase activating protein 35 | 0.0304434 |
| CENPF | centromere protein F, 350/400kDa | 0.0303435 |
| POTEF | POTE ankyrin domain family, member F | 0.0303307 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0301393 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0301379 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0301242 |
| VEGFA | vascular endothelial growth factor A | 0.0299429 |
| NRXN3 | neurexin 3 | 0.0299261 |
| CYLD | cylindromatosis (turban tumor syndrome) | 0.0299111 |
| ZNF148 | zinc finger protein 148 | 0.0296953 |
| PRKCA | protein kinase C, alpha | 0.0292942 |
| CLIC4 | chloride intracellular channel 4 | 0.0290432 |
| INTS6 | integrator complex subunit 6 | 0.0286725 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0284873 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.028383 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0283276 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0282809 |
| AP3S1 | adaptor-related protein complex 3, sigma 1 subunit | 0.0281883 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0277385 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0276529 |
| PKM | pyruvate kinase, muscle | 0.0276491 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0276459 |
| BRD2 | bromodomain containing 2 | 0.0273716 |
| ARB2A | ARB2 cotranscriptional regulator A | 0.0272968 |
| FUS | FUS RNA binding protein | 0.0272873 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0271265 |
| PRELID2 | PRELI domain containing 2 | 0.0264926 |
| NCAPG2 | non-SMC condensin II complex, subunit G2 | 0.026346 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0261395 |
| FMNL2 | formin-like 2 | 0.0258822 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.025685 |
| SQSTM1 | sequestosome 1 | 0.0255155 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0255062 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | 0.0255012 |
| CHD8 | chromodomain helicase DNA binding protein 8 | 0.0254096 |
| ANKRD37 | ankyrin repeat domain 37 | 0.0253883 |
| IL7R | interleukin 7 receptor | 0.025321 |
| RUNX1 | runt-related transcription factor 1 | 0.0252882 |
| MORF4L1 | mortality factor 4 like 1 | 0.0252771 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0249495 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | 0.0249492 |
| MKI67 | marker of proliferation Ki-67 | 0.024805 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.188992 |
| COL6A3 | collagen, type VI, alpha 3 | -0.183487 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.147685 |
| HLA-B | major histocompatibility complex, class I, B | -0.111098 |
| MT2A | metallothionein 2A | -0.0980363 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0852906 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0793897 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.072524 |
| IGFBP7 | insulin-like growth factor binding protein 7 | -0.0724033 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0709482 |
| VIM | vimentin | -0.0686619 |
| VCL | vinculin | -0.0643995 |
| LOXL2 | lysyl oxidase-like 2 | -0.0621663 |
| MT1X | metallothionein 1X | -0.0605997 |
| COL1A2 | collagen, type I, alpha 2 | -0.0591937 |
| STC1 | stanniocalcin 1 | -0.0548455 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0547229 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0519591 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.046634 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0458155 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0452535 |
| FSCN1 | fascin actin-bundling protein 1 | -0.0423226 |
| PRSS23 | protease, serine, 23 | -0.0418477 |
| COL7A1 | collagen, type VII, alpha 1 | -0.0398654 |
| HLA-C | major histocompatibility complex, class I, C | -0.0398202 |
| RRBP1 | ribosome binding protein 1 | -0.0392525 |
| GOLGA4 | golgin A4 | -0.0376925 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | -0.0371244 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.036468 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0363863 |
| SRPK2 | SRSF protein kinase 2 | -0.0362277 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0361565 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0359813 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0351133 |
| FN1 | fibronectin 1 | -0.0340233 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0332589 |
| RPL35A | ribosomal protein L35a | -0.0330214 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.0328394 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | -0.0326023 |
| CLTC | clathrin, heavy chain (Hc) | -0.031744 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.0317016 |
| RPL34 | ribosomal protein L34 | -0.031368 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.0312404 |
| TXNIP | thioredoxin interacting protein | -0.0312366 |
| H3-3B | H3.3 histone B | -0.0311999 |
| TMEM165 | transmembrane protein 165 | -0.0308826 |
| SDC4 | syndecan 4 | -0.0307237 |
| MAPK8 | mitogen-activated protein kinase 8 | -0.0307054 |
| TNNC1 | troponin C type 1 (slow) | -0.0297713 |
| CADM1 | cell adhesion molecule 1 | -0.0295856 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0289465 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0288111 |
| NKTR | natural killer cell triggering receptor | -0.0287723 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0287608 |
| CDK13 | cyclin-dependent kinase 13 | -0.0283136 |
| ACTN4 | actinin, alpha 4 | -0.0282733 |
| C1D | C1D nuclear receptor corepressor | -0.0281576 |
| OGA | O-GlcNAcase | -0.0279084 |
| LUC7L | LUC7-like (S. cerevisiae) | -0.0275691 |
| FKBP10 | FK506 binding protein 10, 65 kDa | -0.0272728 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0271723 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.027123 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0270527 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0265222 |
| TMED9 | transmembrane emp24 protein transport domain containing 9 | -0.0264931 |
| APPBP2 | amyloid beta precursor protein (cytoplasmic tail) binding protein 2 | -0.0263896 |
| SCFD2 | sec1 family domain containing 2 | -0.02634 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0262771 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0261341 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | -0.0260141 |
| DDB1 | damage-specific DNA binding protein 1, 127kDa | -0.0257631 |
| CLINT1 | clathrin interactor 1 | -0.0256768 |
| RPS19 | ribosomal protein S19 | -0.025656 |
| SAR1A | secretion associated, Ras related GTPase 1A | -0.0256497 |
| PMM2 | phosphomannomutase 2 | -0.0254777 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | -0.0254034 |
| SRSF11 | serine/arginine-rich splicing factor 11 | -0.0252748 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0251878 |
| SERF2 | small EDRK-rich factor 2 | -0.0250558 |
| BDP1 | B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB | -0.0248544 |
| TPM4 | tropomyosin 4 | -0.0247793 |
| CFDP1 | craniofacial development protein 1 | -0.0247739 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0246809 |
| AHCTF1 | AT hook containing transcription factor 1 | -0.024105 |
| GNB2 | guanine nucleotide binding protein (G protein), beta polypeptide 2 | -0.0240714 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0240672 |
| KAZN | kazrin, periplakin interacting protein | -0.0239855 |
| CAVIN1 | caveolae associated protein 1 | -0.0239071 |
| HEATR5B | HEAT repeat containing 5B | -0.0238249 |
| RPS21 | ribosomal protein S21 | -0.0237945 |
| WIPF2 | WAS/WASL interacting protein family, member 2 | -0.0233091 |
| AOPEP | aminopeptidase O (putative) | -0.0230741 |
| CTSB | cathepsin B | -0.0229603 |
| AHNAK | AHNAK nucleoprotein | -0.022881 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0227623 |
| MAP4 | microtubule-associated protein 4 | -0.0226222 |
| CIRSR | corepressor of RBPJ and splicing regulator | -0.0225239 |
| SNX6 | sorting nexin 6 | -0.0224925 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.0223528 |
| SMC5 | structural maintenance of chromosomes 5 | -0.022349 |
