| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Busulfan perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Busulfan_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.133992 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.101254 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0699861 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0568945 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.051154 |
| TPX2 | TPX2, microtubule-associated | 0.0488074 |
| NUP58 | nucleoporin 58 | 0.0473079 |
| INTS6 | integrator complex subunit 6 | 0.0430487 |
| ADIPOR2 | adiponectin receptor 2 | 0.0391736 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0390052 |
| MIS18BP1 | MIS18 binding protein 1 | 0.0380909 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0358618 |
| ANXA1 | annexin A1 | 0.0343965 |
| SET | SET nuclear proto-oncogene | 0.0341965 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0333959 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0328822 |
| ANLN | anillin, actin binding protein | 0.0323335 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.0322257 |
| HELZ | helicase with zinc finger | 0.0318749 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0318717 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0314729 |
| CENPF | centromere protein F, 350/400kDa | 0.0314452 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0306301 |
| QKI | QKI, KH domain containing, RNA binding | 0.0303641 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0302453 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0300669 |
| KIF5B | kinesin family member 5B | 0.0287147 |
| OXSR1 | oxidative stress responsive 1 | 0.0284938 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0282707 |
| ECT2 | epithelial cell transforming 2 | 0.0280054 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0276649 |
| CPAP | centrosome assembly and centriole elongation protein | 0.0275855 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0275742 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0275313 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0272968 |
| CENPE | centromere protein E, 312kDa | 0.0271682 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0270381 |
| YTHDF3 | YTH N(6)-methyladenosine RNA binding protein 3 | 0.0267195 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.026635 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0265154 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0261738 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0259702 |
| HIPK3 | homeodomain interacting protein kinase 3 | 0.0259075 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0257186 |
| IFRD1 | interferon-related developmental regulator 1 | 0.0254588 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0253089 |
| SMAD3 | SMAD family member 3 | 0.0244333 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0243459 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0238952 |
| CDC73 | cell division cycle 73 | 0.0235366 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0234538 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0233955 |
| TXNRD1 | thioredoxin reductase 1 | 0.0232827 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0232564 |
| RNASE3 | ribonuclease, RNase A family, 3 | 0.0232511 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0232049 |
| YBX1 | Y box binding protein 1 | 0.0231887 |
| NAP1L4 | nucleosome assembly protein 1-like 4 | 0.0231726 |
| HMMR | hyaluronan-mediated motility receptor (RHAMM) | 0.0229666 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0229456 |
| ZNF292 | zinc finger protein 292 | 0.0228217 |
| XPO1 | exportin 1 | 0.0227765 |
| UBQLN1 | ubiquilin 1 | 0.0223388 |
| AHR | aryl hydrocarbon receptor | 0.0223035 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0221847 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0219668 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.021943 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0217547 |
| SGO2 | shugoshin 2 | 0.021471 |
| JMJD1C | jumonji domain containing 1C | 0.0214065 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0213334 |
| HMGB2 | high mobility group box 2 | 0.0212217 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.021201 |
| SLF1 | SMC5-SMC6 complex localization factor 1 | 0.0211297 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | 0.0210331 |
| TLK2 | tousled-like kinase 2 | 0.0209397 |
| SUPT16H | suppressor of Ty 16 homolog (S. cerevisiae) | 0.02092 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | 0.020917 |
| PPP2R5C | protein phosphatase 2, regulatory subunit B', gamma | 0.0205643 |
| AURKA | aurora kinase A | 0.0203827 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.0203701 |
| GAS2L3 | growth arrest-specific 2 like 3 | 0.0203697 |
| YTHDC1 | YTH domain containing 1 | 0.0200829 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0198162 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0196904 |
| USP12 | ubiquitin specific peptidase 12 | 0.0196351 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0195129 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0194742 |
| CPNE1 | copine I | 0.0194637 |
| RANBP2 | RAN binding protein 2 | 0.0194611 |
| COPB1 | coatomer protein complex, subunit beta 1 | 0.0194448 |
| PCBP2 | poly(rC) binding protein 2 | 0.0193183 |
| FUBP1 | far upstream element (FUSE) binding protein 1 | 0.0193134 |
| AZIN1 | antizyme inhibitor 1 | 0.0192025 |
| RALGAPB | Ral GTPase activating protein, beta subunit (non-catalytic) | 0.0190554 |
| TFRC | transferrin receptor | 0.0190264 |
| NIN | ninein (GSK3B interacting protein) | 0.0190201 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0190148 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0190024 |
| TFG | TRK-fused gene | 0.018997 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TPT1 | tumor protein, translationally-controlled 1 | -0.161732 |
| VIM | vimentin | -0.157114 |
| TMSB10 | thymosin beta 10 | -0.143047 |
| FNDC3B | fibronectin type III domain containing 3B | -0.10317 |
| PTMA | prothymosin, alpha | -0.0974613 |
| CD44 | CD44 molecule (Indian blood group) | -0.0959563 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0819644 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0814781 |
| ANGPTL4 | angiopoietin-like 4 | -0.0807212 |
| IGF2 | insulin-like growth factor 2 | -0.0714405 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0696879 |
| FLNB | filamin B, beta | -0.061853 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0611868 |
| NDRG1 | N-myc downstream regulated 1 | -0.0592038 |
| OSMR | oncostatin M receptor | -0.0589809 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0586884 |
| MT2A | metallothionein 2A | -0.0579353 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0575769 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0566607 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.055176 |
| PRSS23 | protease, serine, 23 | -0.055117 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0542924 |
| SMYD3 | SET and MYND domain containing 3 | -0.0527713 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0518638 |
| HMGA2 | high mobility group AT-hook 2 | -0.0512595 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0508447 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0504797 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0502446 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0495316 |
| PTK2 | protein tyrosine kinase 2 | -0.04926 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0492181 |
| RPL35A | ribosomal protein L35a | -0.0475484 |
| ATXN1 | ataxin 1 | -0.0462234 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0458134 |
| RPLP1 | ribosomal protein, large, P1 | -0.0456803 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0435972 |
| MYO9B | myosin IXB | -0.0434315 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0431389 |
| SDC4 | syndecan 4 | -0.0405952 |
| GPC6 | glypican 6 | -0.0401111 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0399902 |
| S100A9 | S100 calcium binding protein A9 | -0.0388596 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.0387179 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0383371 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0367617 |
| RPL26 | ribosomal protein L26 | -0.0366735 |
| H3-3B | H3.3 histone B | -0.0365422 |
| FMN1 | formin 1 | -0.0363869 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | -0.036172 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.035986 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0354093 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0347805 |
| DNER | delta/notch-like EGF repeat containing | -0.0346266 |
| B2M | beta-2-microglobulin | -0.0346236 |
| STXBP1 | syntaxin binding protein 1 | -0.0346046 |
| EGFR | epidermal growth factor receptor | -0.0343616 |
| NALCN | sodium leak channel, non selective | -0.0343149 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 | -0.0341858 |
| CCDC91 | coiled-coil domain containing 91 | -0.0339838 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0335821 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0335324 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0333213 |
| RPS3 | ribosomal protein S3 | -0.0332332 |
| RBM25 | RNA binding motif protein 25 | -0.0331897 |
| ACTG1 | actin gamma 1 | -0.0331401 |
| NF1 | neurofibromin 1 | -0.0326571 |
| ASPH | aspartate beta-hydroxylase | -0.0324043 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0319696 |
| HLA-B | major histocompatibility complex, class I, B | -0.0319273 |
| LDHA | lactate dehydrogenase A | -0.0315073 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0314196 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0311633 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0308665 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.030622 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0304433 |
| SEPTIN9 | septin 9 | -0.0304424 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.029002 |
| PFN1 | profilin 1 | -0.0286325 |
| IER3 | immediate early response 3 | -0.0286308 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0286188 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | -0.0282732 |
| RPL37A | ribosomal protein L37a | -0.0281999 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0281928 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0281888 |
| RPL12 | ribosomal protein L12 | -0.0281731 |
| CFDP1 | craniofacial development protein 1 | -0.0278971 |
| MT1X | metallothionein 1X | -0.0278811 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0278547 |
| MCL1 | myeloid cell leukemia 1 | -0.0277284 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0276325 |
| DENND5B | DENN/MADD domain containing 5B | -0.0271356 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.0270778 |
| RPS27A | ribosomal protein S27a | -0.0270146 |
| CELF1 | CUGBP, Elav-like family member 1 | -0.0270027 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0266535 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0266518 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0266447 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0265558 |
| HLA-A | major histocompatibility complex, class I, A | -0.0265514 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.0263408 |
