C1D Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description C1D nuclear receptor corepressor|The protein encoded by this gene is a DNA binding and apoptosis-inducing protein and is localized in the nucleus. It is also a Rac3-interacting protein which acts as a corepressor for the thyroid hormone receptor. This protein is thought to regulate TRAX/Translin complex formation. Alternate splicing results in multiple transcript variants that encode the same protein. Multiple pseudogenes of this gene are found on chromosome 10.[provided by RefSeq, Jun 2010] (NCBI Entrez Gene Database, 10438)
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Genes

347 genes differentially expressed following the C1D gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
TMPRSS11D transmembrane protease, serine 11D 3.4462
IL22RA1 interleukin 22 receptor, alpha 1 3.4462
CYTIP cytohesin 1 interacting protein 3.4462
SPINK1 serine peptidase inhibitor, Kazal type 1 3.4462
SLC16A11 solute carrier family 16, member 11 3.4462
NANOS3 nanos homolog 3 (Drosophila) 3.4462
ZFP57 ZFP57 zinc finger protein 3.4462
CD160 CD160 molecule 3.4462
MGAM2 maltase-glucoamylase 2 (putative) 3.4462
TMEM151A transmembrane protein 151A 3.4462
IPCEF1 interaction protein for cytohesin exchange factors 1 3.4462
CD200R1L CD200 receptor 1-like 3.4462
IGFL4 IGF-like family member 4 3.4462
SLC46A2 solute carrier family 46, member 2 3.4462
ZNF284 zinc finger protein 284 3.4462
INHBC inhibin, beta C 3.4462
FGF23 fibroblast growth factor 23 3.4462
SLC6A2 solute carrier family 6 (neurotransmitter transporter), member 2 3.4462
SLC5A8 solute carrier family 5 (sodium/monocarboxylate cotransporter), member 8 3.4462
SLC5A4 solute carrier family 5 (glucose activated ion channel), member 4 3.4462
GPR55 G protein-coupled receptor 55 3.4462
SLC26A7 solute carrier family 26 (anion exchanger), member 7 3.4462
SCN2A sodium channel, voltage gated, type II alpha subunit 3.4462
SLC46A1 solute carrier family 46 (folate transporter), member 1 3.4462
VSTM2B V-set and transmembrane domain containing 2B 3.4462
DCDC2 doublecortin domain containing 2 3.4462
C16ORF86 chromosome 16 open reading frame 86 3.4462
ATP8B4 ATPase, class I, type 8B, member 4 3.4462
KYNU kynureninase 3.4462
HEPHL1 hephaestin-like 1 3.4462
ACOT12 acyl-CoA thioesterase 12 3.4462
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 3.4462
RNF133 ring finger protein 133 3.4462
SPHK1 sphingosine kinase 1 3.4462
ACY3 aminoacylase 3 3.4462
RNF39 ring finger protein 39 3.4462
PRSS36 protease, serine, 36 3.4462
CBY3 chibby homolog 3 (Drosophila) 3.4462
FABP12 fatty acid binding protein 12 3.4462
LBP lipopolysaccharide binding protein 3.4462
MYCT1 myc target 1 3.4462
VAMP5 vesicle-associated membrane protein 5 3.4462
RGL4 ral guanine nucleotide dissociation stimulator-like 4 3.4462
RPL3L ribosomal protein L3-like 3.4462
MS4A15 membrane-spanning 4-domains, subfamily A, member 15 3.4462
TMEM79 transmembrane protein 79 3.4462
LRRC10B leucine rich repeat containing 10B 3.4462
LCN15 lipocalin 15 3.4462
CPB1 carboxypeptidase B1 (tissue) 3.4462
PRDM1 PR domain containing 1, with ZNF domain 3.4462
CSP2 CS pseudogene 2 3.4462
GBP6 guanylate binding protein family, member 6 3.4462
UCMA upper zone of growth plate and cartilage matrix associated 3.4462
EFNB1 ephrin-B1 3.4462
C2ORF72 chromosome 2 open reading frame 72 3.4462
MYH1 myosin, heavy chain 1, skeletal muscle, adult 3.4462
SIM1 single-minded family bHLH transcription factor 1 3.4462
RSPH4A radial spoke head 4 homolog A (Chlamydomonas) 3.4462
TMPRSS4 transmembrane protease, serine 4 3.4462
AGA-DT AGA divergent transcript 3.4462
TMEM196 transmembrane protein 196 3.4462
GOLGA6L7 golgin A6 family like 7 3.4462
DNAI7 dynein axonemal intermediate chain 7 3.4462
CBLIF cobalamin binding intrinsic factor 3.4462
C17ORF114 chromosome 17 open reading frame 114 3.4462
C8ORF90 chromosome 8 open reading frame 90 3.4462
C17ORF113 chromosome 17 open reading frame 113 3.4462
LINC02798 long intergenic non-protein coding RNA 2798 3.4462
TMEM238L transmembrane protein 238 like 3.4462
ACP7 acid phosphatase 7, tartrate resistant (putative) 3.4462
FYB2 FYN binding protein 2 3.4462
INSYN2B inhibitory synaptic factor family member 2B 3.4462
CHCT1 CHD1 helical C-terminal domain containing 1 3.4462
PIERCE2 piercer of microtubule wall 2 3.4462
ATP6V1G2 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2 3.4462
KIAA1614 KIAA1614 3.4462
GAPDHS glyceraldehyde-3-phosphate dehydrogenase, spermatogenic 3.4462
STAR steroidogenic acute regulatory protein 3.4462
PCDHB11 protocadherin beta 11 3.4462
ARL5C ADP-ribosylation factor-like 5C 3.4462
ARL5A ADP-ribosylation factor-like 5A 3.4462
LIPJ lipase, family member J 3.4462
DDX43 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 3.4462
PLCXD3 phosphatidylinositol-specific phospholipase C, X domain containing 3 3.4462
FPR3 formyl peptide receptor 3 3.4462
SYCP2 synaptonemal complex protein 2 3.4462
OR2AT4 olfactory receptor, family 2, subfamily AT, member 4 3.4462
SIM2 single-minded family bHLH transcription factor 2 3.4462
RSPH14 radial spoke head 14 homolog (Chlamydomonas) 3.4462
LRRC73 leucine rich repeat containing 73 3.4462
BLNK B-cell linker 3.4462
C7 complement component 7 3.4462
ZFP3 ZFP3 zinc finger protein 3.4462
CLDN22 claudin 22 3.4462
LECT2 leukocyte cell-derived chemotaxin 2 3.4462
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) 3.4462
SH3TC1 SH3 domain and tetratricopeptide repeats 1 3.4462
TIFA TRAF-interacting protein with forkhead-associated domain 3.4462
BMI1 BMI1 proto-oncogene, polycomb ring finger 3.4462
SBK3 SH3 domain binding kinase family, member 3 3.4462
CHRNA10 cholinergic receptor, nicotinic, alpha 10 (neuronal) 3.4462
CST1 cystatin SN 3.4462
SLITRK3 SLIT and NTRK-like family, member 3 3.4462
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2 3.4462
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3 3.4462
C2CD4D C2 calcium-dependent domain containing 4D 3.4462
BCAS1 breast carcinoma amplified sequence 1 3.4462
TICAM1 toll-like receptor adaptor molecule 1 3.4462
TCF21 transcription factor 21 3.4462
KCNH4 potassium channel, voltage gated eag related subfamily H, member 4 3.4462
GLRA1 glycine receptor, alpha 1 3.4462
PLEKHN1 pleckstrin homology domain containing, family N member 1 3.4462
COL17A1 collagen, type XVII, alpha 1 3.4462
PCDH17 protocadherin 17 3.4462
POU5F2 POU domain class 5, transcription factor 2 3.4462
SSX1 synovial sarcoma, X breakpoint 1 3.4462
NXF3 nuclear RNA export factor 3 3.4462
AZIN2 antizyme inhibitor 2 3.4462
TMEM204 transmembrane protein 204 3.4462
BRDT bromodomain, testis-specific 3.4462
RSAD2 radical S-adenosyl methionine domain containing 2 3.4462
AQP7 aquaporin 7 3.4462
MYF6 myogenic factor 6 (herculin) 3.4462
GAL3ST2 galactose-3-O-sulfotransferase 2 3.4462
FAM222A family with sequence similarity 222, member A 3.4462
DUOX2 dual oxidase 2 3.4462
LCN1 lipocalin 1 3.4462
SPTBN5 spectrin, beta, non-erythrocytic 5 3.4462
SLC32A1 solute carrier family 32 (GABA vesicular transporter), member 1 3.4462
BMX BMX non-receptor tyrosine kinase 3.4462
ADAM7 ADAM metallopeptidase domain 7 3.4462
ZNF471 zinc finger protein 471 3.4462
TMEM187 transmembrane protein 187 3.4462
DNAH10 dynein, axonemal, heavy chain 10 3.4462
SCARF1 scavenger receptor class F, member 1 3.4462
PDZRN4 PDZ domain containing ring finger 4 3.4462
TPH1 tryptophan hydroxylase 1 3.4462
PFN4 profilin family, member 4 3.4462
RIBC2 RIB43A domain with coiled-coils 2 3.4462
ANKDD1B ankyrin repeat and death domain containing 1B 3.4462
NOTCH4 notch 4 3.4462
VENTX VENT homeobox 3.4462
NAT2 N-acetyltransferase 2 (arylamine N-acetyltransferase) 3.4462
PCDHGA12 protocadherin gamma subfamily A, 12 3.4462
ABLIM3 actin binding LIM protein family, member 3 3.4462
NPY neuropeptide Y 3.4462
ARHGAP40 Rho GTPase activating protein 40 3.4462
DENND2D DENN/MADD domain containing 2D 3.4462
RAD9B RAD9 homolog B (S. pombe) 3.4462
TSPEAR thrombospondin-type laminin G domain and EAR repeats 3.4462
RAMP1 receptor (G protein-coupled) activity modifying protein 1 3.4462
CLCF1 cardiotrophin-like cytokine factor 1 3.4462
ARG1 arginase 1 3.4462
SLC38A8 solute carrier family 38, member 8 3.4462
GALNT9 polypeptide N-acetylgalactosaminyltransferase 9 3.4462
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3 3.4462
CRHBP corticotropin releasing hormone binding protein 3.4462
CRYBA1 crystallin, beta A1 3.4462
CDH26 cadherin 26 3.4462
UTS2B urotensin 2B 3.4462
TMEM215 transmembrane protein 215 3.4462
MNX1 motor neuron and pancreas homeobox 1 3.4462
CD36 CD36 molecule (thrombospondin receptor) 3.4462
FBXO40 F-box protein 40 3.4462
FXYD4 FXYD domain containing ion transport regulator 4 3.4462
NRSN1 neurensin 1 3.4462
ZGLP1 zinc finger, GATA-like protein 1 3.4462
PEBP1 phosphatidylethanolamine binding protein 1 3.4196
PLCE1 phospholipase C, epsilon 1 3.32296
GAS1 growth arrest-specific 1 3.26565
MMAA methylmalonic aciduria (cobalamin deficiency) cblA type 3.20955
CRHR1 corticotropin releasing hormone receptor 1 3.20955
GRM4 glutamate receptor, metabotropic 4 3.19767
GNPAT glyceronephosphate O-acyltransferase 3.11292
KCTD5 potassium channel tetramerization domain containing 5 3.04606
SNX25 sorting nexin 25 2.93039
RBM43 RNA binding motif protein 43 2.89993
RPS24 ribosomal protein S24 2.88489
ZBTB16 zinc finger and BTB domain containing 16 2.82455
VGLL4 vestigial-like family member 4 2.81211
PLAAT3 phospholipase A and acyltransferase 3 2.77759
DNAJC17 DnaJ (Hsp40) homolog, subfamily C, member 17 2.64763
NKTR natural killer cell triggering receptor 2.64416
IWS1 IWS1 homolog (S. cerevisiae) 2.6377
PRLR prolactin receptor 2.61586
BATF3 basic leucine zipper transcription factor, ATF-like 3 2.61586
TLR3 toll-like receptor 3 2.61586
C1ORF202 chromosome 1 open reading frame 202 2.61586
PJA1 praja ring finger 1, E3 ubiquitin protein ligase 2.58099
SUSD2 sushi domain containing 2 2.58099
FBXL17 F-box and leucine-rich repeat protein 17 2.58099
PSMF1 proteasome (prosome, macropain) inhibitor subunit 1 (PI31) 2.56492
CRADD CASP2 and RIPK1 domain containing adaptor with death domain 2.49519
WNT5B wingless-type MMTV integration site family, member 5B 2.49519
PON3 paraoxonase 3 2.49519
SUGCT succinyl-CoA:glutarate-CoA transferase 2.49519
PDE1A phosphodiesterase 1A, calmodulin-dependent 2.49519
SP140 SP140 nuclear body protein 2.49519
ZC3H11A zinc finger CCCH-type containing 11A 2.49519
DCX doublecortin 2.49519
GPRASP2 G protein-coupled receptor associated sorting protein 2 2.49519
CEP170 centrosomal protein 170kDa 2.4905
ZNHIT6 zinc finger, HIT-type containing 6 2.38801
TAPBP TAP binding protein (tapasin) 2.38719
P2RY12 purinergic receptor P2Y, G-protein coupled, 12 2.3674
FOCAD focadhesin 2.35142
PPP1R3B protein phosphatase 1, regulatory subunit 3B 2.34919
SP110 SP110 nuclear body protein 2.33448
RNF181 ring finger protein 181 2.29892
FARSB phenylalanyl-tRNA synthetase, beta subunit 2.28635
NEK7 NIMA-related kinase 7 2.28635
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase 2.27886
GNPDA1 glucosamine-6-phosphate deaminase 1 2.22833
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) 2.22298
TCAIM T cell activation inhibitor, mitochondrial 2.2183
POLR2L polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa 2.2174
BICRAL BICRA like chromatin remodeling complex associated protein 2.21481
SP3 Sp3 transcription factor 2.19929
NCDN neurochondrin 2.17543
LEMD3 LEM domain containing 3 2.17543
BOD1L1 biorientation of chromosomes in cell division 1-like 1 2.15835
MOGS mannosyl-oligosaccharide glucosidase 2.15359
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen) 2.15359
MRPS7 mitochondrial ribosomal protein S7 2.13426
SPINT2 serine peptidase inhibitor, Kunitz type, 2 2.12811
GNL1 guanine nucleotide binding protein-like 1 2.12501
IL18BP interleukin 18 binding protein 2.12157
MUS81 MUS81 structure-specific endonuclease subunit 2.11217
SLC25A17 solute carrier family 25 (mitochondrial carrier; peroxisomal membrane protein, 34kDa), member 17 2.11019
KIAA0825 KIAA0825 2.10628
NUDCD3 NudC domain containing 3 2.06231
SETD5 SET domain containing 5 2.06125
ARMCX1 armadillo repeat containing, X-linked 1 2.05775
SIPA1L2 signal-induced proliferation-associated 1 like 2 2.04967
LPCAT1 lysophosphatidylcholine acyltransferase 1 2.04049
PHKG2 phosphorylase kinase, gamma 2 (testis) 2.03786
SPINDOC spindlin interactor and repressor of chromatin binding 2.03644
ZNF141 zinc finger protein 141 2.02685
ADO 2-aminoethanethiol (cysteamine) dioxygenase 2.01464
ZCCHC8 zinc finger, CCHC domain containing 8 2.0109

decreased expression

Symbol Name Standardized Value
PROK2 prokineticin 2 -3.4462
PELI3 pellino E3 ubiquitin protein ligase family member 3 -3.4462
KAT5 K(lysine) acetyltransferase 5 -3.4462
GBE1 glucan (1,4-alpha-), branching enzyme 1 -3.4462
C12ORF42 chromosome 12 open reading frame 42 -3.4462
CCDC142 coiled-coil domain containing 142 -3.4462
PHGDH phosphoglycerate dehydrogenase -3.28079
AURKC aurora kinase C -3.04606
ATP6V0A4 ATPase, H+ transporting, lysosomal V0 subunit a4 -3.04606
HTR2B 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled -3.04606
IQCJ IQ motif containing J -3.04606
MAPK15 mitogen-activated protein kinase 15 -3.04606
TSNAXIP1 translin-associated factor X interacting protein 1 -3.04606
VSTM2A V-set and transmembrane domain containing 2A -3.04606
NAP1L5 nucleosome assembly protein 1-like 5 -3.04606
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1 -3.04606
MYO1A myosin IA -3.04606
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) -3.04606
FAM110D family with sequence similarity 110, member D -3.04606
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28 -3.04606
CCDC33 coiled-coil domain containing 33 -3.04606
PARP12 poly (ADP-ribose) polymerase family, member 12 -3.04606
ABCG5 ATP-binding cassette, sub-family G (WHITE), member 5 -3.04606
PRCD progressive rod-cone degeneration -3.04606
SLC25A20 solute carrier family 25 (carnitine/acylcarnitine translocase), member 20 -3.04606
GABRG3 gamma-aminobutyric acid (GABA) A receptor, gamma 3 -3.04606
PNMA6A paraneoplastic Ma antigen family member 6A -3.04606
JUNB jun B proto-oncogene -3.04606
LAT linker for activation of T cells -3.04606
ZNF837 zinc finger protein 837 -3.04606
PYY peptide YY -3.04606
RIPPLY2 ripply transcriptional repressor 2 -3.04606
GDPD5 glycerophosphodiester phosphodiesterase domain containing 5 -3.04606
RADX RPA1 related single stranded DNA binding protein, X-linked -3.04606
KCTD19 potassium channel tetramerization domain containing 19 -3.04606
CFD complement factor D (adipsin) -3.04606
PVALEF parvalbumin like EF-hand containing -3.04606
TAFA1 TAFA chemokine like family member 1 -3.04606
LETM2 leucine zipper-EF-hand containing transmembrane protein 2 -3.04606
MYT1L myelin transcription factor 1-like -3.04606
GPR3 G protein-coupled receptor 3 -3.04606
SLC7A9 solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9 -3.04606
SERTAD1 SERTA domain containing 1 -3.04606
ZNF25 zinc finger protein 25 -3.04606
PCDHGC3 protocadherin gamma subfamily C, 3 -3.04606
COA8 cytochrome c oxidase assembly factor 8 -2.97991
NPIPA1 nuclear pore complex interacting protein family, member A1 -2.94672
LY75 lymphocyte antigen 75 -2.94285
SKP1 S-phase kinase-associated protein 1 -2.78959
FAM114A2 family with sequence similarity 114, member A2 -2.7859
SHOC1 shortage in chiasmata 1 -2.75633
FAM53A family with sequence similarity 53, member A -2.75004
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha -2.70531
HROB homologous recombination factor with OB-fold -2.69093
MARCHF6 membrane associated ring-CH-type finger 6 -2.65501
IFT122 intraflagellar transport 122 -2.65151
CMC2 C-x(9)-C motif containing 2 -2.61586
ZNF680 zinc finger protein 680 -2.61501
CFL1 cofilin 1 (non-muscle) -2.59671
SLC15A3 solute carrier family 15 (oligopeptide transporter), member 3 -2.56345
RBX1 ring-box 1, E3 ubiquitin protein ligase -2.56219
ELOVL2 ELOVL fatty acid elongase 2 -2.54911
DZIP3 DAZ interacting zinc finger protein 3 -2.54026
RAD17 RAD17 homolog (S. pombe) -2.49519
IQGAP1 IQ motif containing GTPase activating protein 1 -2.49073
SIPA1 signal-induced proliferation-associated 1 -2.4301
POC1A POC1 centriolar protein A -2.36867
TIMP4 TIMP metallopeptidase inhibitor 4 -2.3674
FAAH fatty acid amide hydrolase -2.3674
RPL3 ribosomal protein L3 -2.3674
LRFN1 leucine rich repeat and fibronectin type III domain containing 1 -2.3674
SOX9 SRY (sex determining region Y)-box 9 -2.3674
DTD1 D-tyrosyl-tRNA deacylase 1 -2.36496
TM2D2 TM2 domain containing 2 -2.36154
USP42 ubiquitin specific peptidase 42 -2.36154
HCN4 hyperpolarization activated cyclic nucleotide gated potassium channel 4 -2.34289
ZNF865 zinc finger protein 865 -2.31908
GSTZ1 glutathione S-transferase zeta 1 -2.30869
MEMO1 mediator of cell motility 1 -2.30557
SRFBP1 serum response factor binding protein 1 -2.30172
NDUFB8 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa -2.29892
PROCR protein C receptor, endothelial -2.25246
NOL6 nucleolar protein 6 (RNA-associated) -2.24161
DNPEP aspartyl aminopeptidase -2.23839
FAM117B family with sequence similarity 117, member B -2.22818
PLXNC1 plexin C1 -2.22818
FNDC10 fibronectin type III domain containing 10 -2.2183
NPDC1 neural proliferation, differentiation and control, 1 -2.20658
AGGF1 angiogenic factor with G patch and FHA domains 1 -2.18889
PSMG1 proteasome (prosome, macropain) assembly chaperone 1 -2.15359
IGBP1 immunoglobulin (CD79A) binding protein 1 -2.15359
VPS35L VPS35 endosomal protein sorting factor like -2.12501
SLC27A1 solute carrier family 27 (fatty acid transporter), member 1 -2.12501
KIF21B kinesin family member 21B -2.12501
MLX MLX, MAX dimerization protein -2.11921
CIBAR1 CBY1 interacting BAR domain containing 1 -2.11462
EHMT1 euchromatic histone-lysine N-methyltransferase 1 -2.11217
MAP3K3 mitogen-activated protein kinase kinase kinase 3 -2.11009
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa -2.08813
YAP1 Yes-associated protein 1 -2.06002
GCNT4 glucosaminyl (N-acetyl) transferase 4, core 2 -2.05775
LEFTY1 left-right determination factor 1 -2.05047
ZBED3 zinc finger, BED-type containing 3 -2.03786
AGPS alkylglycerone phosphate synthase -2.03733
NEK1 NIMA-related kinase 1 -2.01907
WNK2 WNK lysine deficient protein kinase 2 -2.01092
LUC7L LUC7-like (S. cerevisiae) -2.0109