C1R Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description complement component 1, r subcomponent| (NCBI Entrez Gene Database, 715)
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Genes

299 genes differentially expressed following the C1R gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
DTHD1 death domain containing 1 2.1182
MAP9 microtubule-associated protein 9 2.1182
OR52H1 olfactory receptor, family 52, subfamily H, member 1 2.1182
CABP4 calcium binding protein 4 2.1182
NANOS2 nanos homolog 2 (Drosophila) 2.1182
TRIM10 tripartite motif containing 10 2.1182
DCAF4L2 DDB1 and CUL4 associated factor 4-like 2 2.1182
PRODH2 proline dehydrogenase (oxidase) 2 2.1182
PCDHGB3 protocadherin gamma subfamily B, 3 2.1182
AFM afamin 2.1182
EPN1 epsin 1 2.1182
LRRD1 leucine-rich repeats and death domain containing 1 2.1182
INHBB inhibin, beta B 2.1182
PCDHA2 protocadherin alpha 2 2.1182
IZUMO4 IZUMO family member 4 2.1182
RLBP1 retinaldehyde binding protein 1 2.1182
RS1 retinoschisin 1 2.1182
OR2A1 olfactory receptor, family 2, subfamily A, member 1 2.1182
TAS2R5 taste receptor, type 2, member 5 2.1182
MS4A6E membrane-spanning 4-domains, subfamily A, member 6E 2.1182
SLCO1B3 solute carrier organic anion transporter family, member 1B3 2.1182
GJA8 gap junction protein, alpha 8, 50kDa 2.1182
SLC25A41 solute carrier family 25, member 41 2.1182
PDE7B phosphodiesterase 7B 2.1182
BMP6 bone morphogenetic protein 6 2.1182
SPHK1 sphingosine kinase 1 2.1182
NMUR2 neuromedin U receptor 2 2.1182
SPON2 spondin 2, extracellular matrix protein 2.1182
OR56A5 olfactory receptor, family 56, subfamily A, member 5 2.1182
FAM9C family with sequence similarity 9, member C 2.1182
FGF6 fibroblast growth factor 6 2.1182
PRSS22 protease, serine, 22 2.1182
DHRS9 dehydrogenase/reductase (SDR family) member 9 2.1182
TAS2R10 taste receptor, type 2, member 10 2.1182
NPIPA8 nuclear pore complex interacting protein family, member A8 2.1182
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 2.1182
RSPO1 R-spondin 1 2.1182
GPR22 G protein-coupled receptor 22 2.1182
SLC23A3 solute carrier family 23, member 3 2.1182
SLC5A11 solute carrier family 5 (sodium/inositol cotransporter), member 11 2.1182
TRPV2 transient receptor potential cation channel, subfamily V, member 2 2.1182
NLRP10 NLR family, pyrin domain containing 10 2.1182
UBA7 ubiquitin-like modifier activating enzyme 7 2.1182
KIAA2012 KIAA2012 2.1182
ADAT3 adenosine deaminase, tRNA-specific 3 2.1182
SPDEF SAM pointed domain containing ETS transcription factor 2.1182
VSX2 visual system homeobox 2 2.1182
OR9H1 olfactory receptor family 9 subfamily H member 1 pseudogene (gene/pseudogene) 2.1182
LORICRIN loricrin cornified envelope precursor protein 2.1182
GUCY1A1 guanylate cyclase 1 soluble subunit alpha 1 2.1182
LOC112694756 uncharaterized LOC112694756 2.1182
CCN3 cellular communication network factor 3 2.1182
GNGT2 guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2 2.1182
CES4A carboxylesterase 4A 2.1182
ELFN2 extracellular leucine-rich repeat and fibronectin type III domain containing 2 2.1182
GIPC3 GIPC PDZ domain containing family, member 3 2.1182
C2ORF72 chromosome 2 open reading frame 72 2.1182
BNIP5 BCL2 interacting protein 5 2.1182
CATSPERZ catsper channel auxiliary subunit zeta 2.1182
CFAP161 cilia and flagella associated protein 161 2.1182
CSNK2A2IP casein kinase 2 subunit alpha' interacting protein 2.1182
DRC5 dynein regulatory complex subunit 5 2.1182
OR56B2 olfactory receptor family 56 subfamily B member 2 2.1182
H3C13 H3 clustered histone 13 2.1182
ZNG1E Zn regulated GTPase metalloprotein activator 1E 2.1182
HOATZ HOATZ cilia and flagella associated protein 2.1182
DNAAF6 dynein axonemal assembly factor 6 2.1182
NFILZ NFIL3 like basic leucine zipper 2.1182
CBY2 chibby family member 2 2.1182
ADGRG3 adhesion G protein-coupled receptor G3 2.1182
C9ORF43 chromosome 9 open reading frame 43 2.1182
CCR3 chemokine (C-C motif) receptor 3 2.1182
CDK5R2 cyclin-dependent kinase 5, regulatory subunit 2 (p39) 2.1182
RASAL3 RAS protein activator like 3 2.1182
C1QTNF1 C1q and tumor necrosis factor related protein 1 2.1182
BHLHA9 basic helix-loop-helix family, member a9 2.1182
DMBX1 diencephalon/mesencephalon homeobox 1 2.1182
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 2.1182
LDHAL6B lactate dehydrogenase A-like 6B 2.1182
MAG myelin associated glycoprotein 2.1182
CCR9 chemokine (C-C motif) receptor 9 2.1182
DLC1 DLC1 Rho GTPase activating protein 2.1182
CELA2A chymotrypsin-like elastase family, member 2A 2.1182
SMLR1 small leucine-rich protein 1 2.1182
GC group-specific component (vitamin D binding protein) 2.1182
HSPA6 heat shock 70kDa protein 6 (HSP70B') 2.1182
IMPG2 interphotoreceptor matrix proteoglycan 2 2.1182
SELL selectin L 2.1182
GATA3 GATA binding protein 3 2.1182
DLK2 delta-like 2 homolog (Drosophila) 2.1182
PRG4 proteoglycan 4 2.1182
C6 complement component 6 2.1182
CCR6 chemokine (C-C motif) receptor 6 2.1182
OR5A1 olfactory receptor, family 5, subfamily A, member 1 2.1182
KCNA6 potassium channel, voltage gated shaker related subfamily A, member 6 2.1182
ALOXE3 arachidonate lipoxygenase 3 2.1182
SERPINA6 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6 2.1182
DSC1 desmocollin 1 2.1182
COMP cartilage oligomeric matrix protein 2.1182
CDK20 cyclin-dependent kinase 20 2.1182
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1 2.1182
CER1 cerberus 1, DAN family BMP antagonist 2.1182
HOPX HOP homeobox 2.1182
P2RX3 purinergic receptor P2X, ligand gated ion channel, 3 2.1182
PLA1A phospholipase A1 member A 2.1182
MUC16 mucin 16, cell surface associated 2.1182
FAM209A family with sequence similarity 209, member A 2.1182
C18ORF63 chromosome 18 open reading frame 63 2.1182
CERKL ceramide kinase-like 2.1182
RABGGTB Rab geranylgeranyltransferase, beta subunit 2.1182
TNR tenascin R 2.1182
SERPINB12 serpin peptidase inhibitor, clade B (ovalbumin), member 12 2.1182
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1 2.1182
NOX3 NADPH oxidase 3 2.1182
ZNF627 zinc finger protein 627 2.1182
CALHM3 calcium homeostasis modulator 3 2.1182
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled 2.1182
FAM135B family with sequence similarity 135, member B 2.1182
MUC7 mucin 7, secreted 2.1182
POMT2 protein-O-mannosyltransferase 2 2.1182
NKX6-1 NK6 homeobox 1 2.1182
KLHL10 kelch-like family member 10 2.1182
ERVV-1 endogenous retrovirus group V, member 1 2.1182
LMX1B LIM homeobox transcription factor 1, beta 2.1182
TTC24 tetratricopeptide repeat domain 24 2.1182
MB myoglobin 2.1182
TMEM163 transmembrane protein 163 2.1182
PDK4 pyruvate dehydrogenase kinase, isozyme 4 2.1182
OR52N2 olfactory receptor, family 52, subfamily N, member 2 2.1182
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) 2.1182
PLCD4 phospholipase C, delta 4 2.1182
IL3RA interleukin 3 receptor, alpha (low affinity) 2.1182
CHRNA1 cholinergic receptor, nicotinic, alpha 1 (muscle) 2.1182
LRRC15 leucine rich repeat containing 15 2.1182
ITGB7 integrin, beta 7 2.1182
PHACTR2 phosphatase and actin regulator 2 2.1182
CRYBA1 crystallin, beta A1 2.1182
TG thyroglobulin 2.1182
DMRT3 doublesex and mab-3 related transcription factor 3 2.1182
IP6K2 inositol hexakisphosphate kinase 2 2.1182
NT5C1B 5'-nucleotidase, cytosolic IB 2.1182
OR52N4 olfactory receptor, family 52, subfamily N, member 4 (gene/pseudogene) 2.1182
NGB neuroglobin 2.1182
SCN3A sodium channel, voltage gated, type III alpha subunit 2.1182
NR2E3 nuclear receptor subfamily 2, group E, member 3 2.1182
GH2 growth hormone 2 2.1182
SLX1A SLX1 structure-specific endonuclease subunit homolog A (S. cerevisiae) 2.1182
MED31 mediator complex subunit 31 2.1182
GLT6D1 glycosyltransferase 6 domain containing 1 2.1182
POPDC2 popeye domain containing 2 2.1182
POLG polymerase (DNA directed), gamma 2.1182
APOL1 apolipoprotein L, 1 2.1182
RP1 retinitis pigmentosa 1 (autosomal dominant) 2.1182
AMACR alpha-methylacyl-CoA racemase 2.1182
TRAF3IP3 TRAF3 interacting protein 3 2.1182
EIF3CL eukaryotic translation initiation factor 3, subunit C-like 2.1182
TMPRSS15 transmembrane protease, serine 15 2.1182
SLCO1C1 solute carrier organic anion transporter family, member 1C1 2.1182
NLRP5 NLR family, pyrin domain containing 5 2.1182
NUTM2A NUT family member 2A 2.1182
WDR20 WD repeat domain 20 2.1182
TGFA transforming growth factor, alpha 2.1182
ITGBL1 integrin, beta-like 1 (with EGF-like repeat domains) 2.1182
NPPA natriuretic peptide A 2.1182
MEIG1 meiosis/spermiogenesis associated 1 2.1182
HGFAC HGF activator 2.1182
CD22 CD22 molecule 2.1182
BCAS1 breast carcinoma amplified sequence 1 2.1182
SMIM22 small integral membrane protein 22 2.1182
DES desmin 2.1182
MNX1 motor neuron and pancreas homeobox 1 2.1182
PLA2G4D phospholipase A2, group IVD (cytosolic) 2.1182
ZMYND10 zinc finger, MYND-type containing 10 2.1182
IRX4 iroquois homeobox 4 2.1182
ASCL3 achaete-scute family bHLH transcription factor 3 2.1182
CD177 CD177 molecule 2.1182
SPNS3 spinster homolog 3 (Drosophila) 2.1182
TAFA5 TAFA chemokine like family member 5 2.09657
GARIN5A golgi associated RAB2 interactor 5A 2.09657
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4 2.09657
SH3BGRL3 SH3 domain binding glutamate-rich protein like 3 2.09657
BIN3 bridging integrator 3 2.09657
PLK5 polo-like kinase 5 2.09514
FH fumarate hydratase 2.0848
DGUOK deoxyguanosine kinase 2.0848
GPR78 G protein-coupled receptor 78 2.07962
ZNF287 zinc finger protein 287 2.07962
ZDHHC14 zinc finger, DHHC-type containing 14 2.07962
ENOSF1 enolase superfamily member 1 2.07962
NDUFAF8 NADH:ubiquinone oxidoreductase complex assembly factor 8 2.07365
HAGH hydroxyacylglutathione hydrolase 2.06863
CZIB CXXC motif containing zinc binding protein 2.03604
BOC BOC cell adhesion associated, oncogene regulated 2.02056
ARL13B ADP-ribosylation factor-like 13B 2.0196
USP37 ubiquitin specific peptidase 37 2.0196
FARSB phenylalanyl-tRNA synthetase, beta subunit 2.01912
PCF11 PCF11 cleavage and polyadenylation factor subunit 2.01912
ORC1 origin recognition complex, subunit 1 2.01651
VWA8 von Willebrand factor A domain containing 8 2.0128
KCNMB1 potassium channel subfamily M regulatory beta subunit 1 2.01056
ADAMTS18 ADAM metallopeptidase with thrombospondin type 1 motif, 18 2.01056
KIAA1614 KIAA1614 2.01056
CPOX coproporphyrinogen oxidase 2.00341
ZER1 zyg-11 related, cell cycle regulator 2.00341
MIEN1 migration and invasion enhancer 1 2.00259

decreased expression

Symbol Name Standardized Value
CATSPERT catsper channel auxiliary subunit tau -2.1182
PDZD9 PDZ domain containing 9 -2.1182
SH2D7 SH2 domain containing 7 -2.1182
PLEKHJ1 pleckstrin homology domain containing, family J member 1 -2.1182
MEI1 meiosis inhibitor 1 -2.1182
FBLN7 fibulin 7 -2.1182
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 -2.1182
ROBO2 roundabout, axon guidance receptor, homolog 2 (Drosophila) -2.1182
TMEM79 transmembrane protein 79 -2.1182
GNRHR gonadotropin-releasing hormone receptor -2.1182
RFX6 regulatory factor X, 6 -2.1182
CRYGN crystallin, gamma N -2.1182
PMVK phosphomevalonate kinase -2.1182
CORO6 coronin 6 -2.1182
PBX2 pre-B-cell leukemia homeobox 2 -2.1182
MAP2K4 mitogen-activated protein kinase kinase 4 -2.1182
LOC105378220 macrophage receptor MARCO-like -2.1182
LHCGR luteinizing hormone/choriogonadotropin receptor -2.1182
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 -2.1182
SPMAP2L sperm microtubule associated protein 2 like -2.1182
IL6ST-DT IL6ST divergent transcript -2.1182
LINC02762 long intergenic non-protein coding RNA 2762 -2.1182
PRRT1B proline rich transmembrane protein 1B -2.1182
INKA1 inka box actin regulator 1 -2.1182
DNAI7 dynein axonemal intermediate chain 7 -2.1182
PUS10 pseudouridylate synthase 10 -2.1182
GPR34 G protein-coupled receptor 34 -2.1182
ATRIP ATR interacting protein -2.1182
WDR64 WD repeat domain 64 -2.1182
CD70 CD70 molecule -2.1182
ACE2 angiotensin I converting enzyme 2 -2.1182
HIF1AN hypoxia inducible factor 1, alpha subunit inhibitor -2.1182
CRACR2B calcium release activated channel regulator 2B -2.1182
TMEM235 transmembrane protein 235 -2.1182
POLR2J2 polymerase (RNA) II (DNA directed) polypeptide J2 -2.1182
RNASE1 ribonuclease, RNase A family, 1 (pancreatic) -2.1182
CITED1 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1 -2.1182
DYNC1LI1 dynein, cytoplasmic 1, light intermediate chain 1 -2.1182
RAB40C RAB40C, member RAS oncogene family -2.1182
UBL3 ubiquitin-like 3 -2.1182
CERS3 ceramide synthase 3 -2.1182
LAYN layilin -2.1182
SCML1 sex comb on midleg-like 1 (Drosophila) -2.1182
KIF21A kinesin family member 21A -2.1182
MEGF10-DT MEGF10 divergent transcript -2.1182
SNX31 sorting nexin 31 -2.1182
P2RY11 purinergic receptor P2Y, G-protein coupled, 11 -2.1182
CCDC184 coiled-coil domain containing 184 -2.1182
ISL1 ISL LIM homeobox 1 -2.1182
CNR1 cannabinoid receptor 1 (brain) -2.1182
PRSS33 protease, serine, 33 -2.1182
B9D2 B9 protein domain 2 -2.1182
SLC22A31 solute carrier family 22, member 31 -2.1182
EBF4 early B-cell factor 4 -2.1182
DNAJB7 DnaJ (Hsp40) homolog, subfamily B, member 7 -2.1182
APCDD1 adenomatosis polyposis coli down-regulated 1 -2.1182
UTP18 UTP18 small subunit (SSU) processome component homolog (yeast) -2.1182
LPAR5 lysophosphatidic acid receptor 5 -2.1182
NLRP9 NLR family, pyrin domain containing 9 -2.1182
GPRC5B G protein-coupled receptor, class C, group 5, member B -2.1182
C9ORF57 chromosome 9 open reading frame 57 -2.1182
APOB apolipoprotein B -2.1182
OR52A1 olfactory receptor, family 52, subfamily A, member 1 -2.1182
CARD8 caspase recruitment domain family, member 8 -2.1182
EIF2B3 eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa -2.10802
CLEC16A C-type lectin domain family 16, member A -2.09898
MYT1L myelin transcription factor 1-like -2.09657
RPL38 ribosomal protein L38 -2.09657
GDPD4 glycerophosphodiester phosphodiesterase domain containing 4 -2.09657
EHD2 EH-domain containing 2 -2.09657
DNAAF3 dynein, axonemal, assembly factor 3 -2.09657
TRAM1 translocation associated membrane protein 1 -2.09657
AKIP1 A kinase (PRKA) interacting protein 1 -2.09184
APC adenomatous polyposis coli -2.0848
TUBD1 tubulin, delta 1 -2.07444
LCMT2 leucine carboxyl methyltransferase 2 -2.07365
EFNA4 ephrin-A4 -2.06997
ACSF2 acyl-CoA synthetase family member 2 -2.0686
SURF1 surfeit 1 -2.03933
TET1 tet methylcytosine dioxygenase 1 -2.03656
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon -2.03604
IFI27L2 interferon, alpha-inducible protein 27-like 2 -2.02159
LTB4R leukotriene B4 receptor -2.02056
ADPRH ADP-ribosylarginine hydrolase -2.02056
SYNJ2BP synaptojanin 2 binding protein -2.01912
PRB3 proline-rich protein BstNI subfamily 3 -2.01617
ACSL6 acyl-CoA synthetase long-chain family member 6 -2.01617
SEMA4F sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F -2.0128
NOVA2 neuro-oncological ventral antigen 2 -2.01056
GLDC glycine dehydrogenase (decarboxylating) -2.01056
MSH5 mutS homolog 5 -2.00764
ADAMTS4 ADAM metallopeptidase with thrombospondin type 1 motif, 4 -2.00736
CLDN12 claudin 12 -2.00341
SLC25A44 solute carrier family 25, member 44 -2.00259