| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | complement component 1, s subcomponent|This gene encodes a serine protease, which is a major constituent of the human complement subcomponent C1. C1s associates with two other complement components C1r and C1q in order to yield the first component of the serum complement system. Defects in this gene are the cause of selective C1s deficiency. [provided by RefSeq, Mar 2009] (NCBI Entrez Gene Database, 716) |
| External Link | https://ncbi.nlm.nih.gov/gene/716 |
| Similar Terms | |
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499 genes differentially expressed following the C1S gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LTF | lactotransferrin | 0.0252203 |
| S100A9 | S100 calcium binding protein A9 | 0.0227565 |
| KRT15 | keratin 15, type I | 0.0208989 |
| LCN2 | lipocalin 2 | 0.0193911 |
| KRT14 | keratin 14, type I | 0.0185484 |
| KRT5 | keratin 5, type II | 0.0184339 |
| PI3 | peptidase inhibitor 3, skin-derived | 0.0184269 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0181024 |
| S100A8 | S100 calcium binding protein A8 | 0.017963 |
| XIC | X chromosome inactivation center | 0.0172051 |
| S100P | S100 calcium binding protein P | 0.0170989 |
| BHLHE41 | basic helix-loop-helix family, member e41 | 0.0159046 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) | 0.015871 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | 0.0157156 |
| KLK10 | kallikrein-related peptidase 10 | 0.015522 |
| TRIM29 | tripartite motif containing 29 | 0.0154886 |
| KRT13 | keratin 13, type I | 0.0153805 |
| EMP1 | epithelial membrane protein 1 | 0.0151521 |
| SPRR3 | small proline-rich protein 3 | 0.0148492 |
| CSTA | cystatin A (stefin A) | 0.0146314 |
| CCN2 | cellular communication network factor 2 | 0.0145589 |
| IL1RN | interleukin 1 receptor antagonist | 0.014409 |
| SLPI | secretory leukocyte peptidase inhibitor | 0.0143003 |
| BAMBI | BMP and activin membrane-bound inhibitor | 0.0141342 |
| PITX3 | paired-like homeodomain 3 | 0.0141326 |
| S100A7 | S100 calcium binding protein A7 | 0.0137319 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | 0.0134741 |
| STC2 | stanniocalcin 2 | 0.0124024 |
| RGCC | regulator of cell cycle | 0.0123303 |
| SPRR2B | small proline-rich protein 2B | 0.0122157 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | 0.0120758 |
| BCL2A1 | BCL2-related protein A1 | 0.0117927 |
| CEACAM8 | carcinoembryonic antigen-related cell adhesion molecule 8 | 0.011783 |
| BPI | bactericidal/permeability-increasing protein | 0.0117652 |
| GABRP | gamma-aminobutyric acid (GABA) A receptor, pi | 0.0116482 |
| S100A12 | S100 calcium binding protein A12 | 0.011587 |
| ANXA1 | annexin A1 | 0.011555 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.011547 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming | 0.0114844 |
| ATF3 | activating transcription factor 3 | 0.0114273 |
| HSPA1A | heat shock 70kDa protein 1A | 0.0113932 |
| RCAN1 | regulator of calcineurin 1 | 0.0113175 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0113084 |
| FAM171A1 | family with sequence similarity 171, member A1 | 0.0112073 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0110159 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 0.0110035 |
| KRT19 | keratin 19, type I | 0.0108992 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.0108656 |
| RHCG | Rh family, C glycoprotein | 0.0108497 |
| FOSL2 | FOS-like antigen 2 | 0.0107021 |
| SPRR1A | small proline-rich protein 1A | 0.0106855 |
| FXYD3 | FXYD domain containing ion transport regulator 3 | 0.0105331 |
| TXLNA | taxilin alpha | 0.0105242 |
| MMP7 | matrix metallopeptidase 7 | 0.0104634 |
| RRAGD | Ras-related GTP binding D | 0.010358 |
| COG7 | component of oligomeric golgi complex 7 | 0.010294 |
| PALLD | palladin, cytoskeletal associated protein | 0.0102546 |
| KRT6A | keratin 6A, type II | 0.0102231 |
| AOC1 | amine oxidase, copper containing 1 | 0.0102065 |
| MAL | mal, T-cell differentiation protein | 0.0101831 |
| SPRR1B | small proline-rich protein 1B | 0.010093 |
| PRKCA | protein kinase C, alpha | 0.0100708 |
| BBOX1 | butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 | 0.010052 |
| PTN | pleiotrophin | 0.00995913 |
| MME | membrane metallo-endopeptidase | 0.00995902 |
| PCOLCE2 | procollagen C-endopeptidase enhancer 2 | 0.0099229 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 0.00991772 |
| AREG | amphiregulin | 0.00988023 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.00980135 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | 0.009705 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.00963608 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 | 0.00960275 |
| ALOX5AP | arachidonate 5-lipoxygenase-activating protein | 0.00956111 |
| DSP | desmoplakin | 0.00952051 |
| HTRA1 | HtrA serine peptidase 1 | 0.00950856 |
| PKP1 | plakophilin 1 | 0.00942232 |
| CST7 | cystatin F (leukocystatin) | 0.00940862 |
| ETHE1 | ethylmalonic encephalopathy 1 | 0.0093915 |
| LRRN3 | leucine rich repeat neuronal 3 | 0.00934835 |
| MMP8 | matrix metallopeptidase 8 | 0.00930583 |
| CRISP3 | cysteine-rich secretory protein 3 | 0.00929729 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.00929019 |
| DEFA4 | defensin, alpha 4, corticostatin | 0.00927613 |
| CRABP2 | cellular retinoic acid binding protein 2 | 0.00927604 |
| ZNF185 | zinc finger protein 185 (LIM domain) | 0.00921932 |
| TARP | TCR gamma alternate reading frame protein | 0.00920072 |
| TFF1 | trefoil factor 1 | 0.00919899 |
| DSG3 | desmoglein 3 | 0.00916657 |
| KLK11 | kallikrein-related peptidase 11 | 0.00904239 |
| KRT6B | keratin 6B, type II | 0.0090277 |
| MYB | v-myb avian myeloblastosis viral oncogene homolog | 0.00902182 |
| PADI2 | peptidyl arginine deiminase, type II | 0.00901431 |
| SCGB2A2 | secretoglobin, family 2A, member 2 | 0.0089898 |
| SRGN | serglycin | 0.00897264 |
| CA12 | carbonic anhydrase XII | 0.0089633 |
| LYPD3 | LY6/PLAUR domain containing 3 | 0.00892476 |
| S100A2 | S100 calcium binding protein A2 | 0.00882573 |
| PDZK1IP1 | PDZK1 interacting protein 1 | 0.00879311 |
| HIST1H2AC | histone cluster 1, H2ac | 0.00878792 |
| SFN | stratifin | 0.00877048 |
| KRT16 | keratin 16, type I | 0.00875018 |
| THBS1 | thrombospondin 1 | 0.00873852 |
| ECM1 | extracellular matrix protein 1 | 0.00871591 |
| IRS2 | insulin receptor substrate 2 | 0.00869498 |
| CALB1 | calbindin 1, 28kDa | 0.00867944 |
| IGFBP4 | insulin-like growth factor binding protein 4 | 0.00867783 |
| CRNN | cornulin | 0.00862409 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F | 0.00857536 |
| CLIC3 | chloride intracellular channel 3 | 0.00857387 |
| NEBL | nebulette | 0.00853281 |
| IL1B | interleukin 1, beta | 0.00850281 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) | 0.00844681 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.00841821 |
| CSRP2 | cysteine and glycine-rich protein 2 | 0.00839341 |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) | 0.00836577 |
| CHD7 | chromodomain helicase DNA binding protein 7 | 0.00834827 |
| LY6D | lymphocyte antigen 6 complex, locus D | 0.00833558 |
| CRELD2 | cysteine-rich with EGF-like domains 2 | 0.00832538 |
| EHF | ets homologous factor | 0.00828463 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | 0.00828121 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | 0.00826817 |
| DACH1 | dachshund family transcription factor 1 | 0.00820083 |
| TP53I3 | tumor protein p53 inducible protein 3 | 0.00819874 |
| IRF6 | interferon regulatory factor 6 | 0.00817197 |
| TRIM16 | tripartite motif containing 16 | 0.00815724 |
| ALDH3B1 | aldehyde dehydrogenase 3 family, member B1 | 0.00814692 |
| COG5 | component of oligomeric golgi complex 5 | 0.00813314 |
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 | 0.00811792 |
| FAM107A | family with sequence similarity 107, member A | 0.00809646 |
| CAPG | capping protein (actin filament), gelsolin-like | 0.00804777 |
| INHBA | inhibin, beta A | 0.00796469 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.00791716 |
| SLC5A6 | solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 | 0.0078997 |
| TRIP6 | thyroid hormone receptor interactor 6 | 0.00784779 |
| ITGAM | integrin, alpha M (complement component 3 receptor 3 subunit) | 0.00783472 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.00781244 |
| WIPI1 | WD repeat domain, phosphoinositide interacting 1 | 0.00780562 |
| C5AR1 | complement component 5a receptor 1 | 0.00778872 |
| ID4 | inhibitor of DNA binding 4, dominant negative helix-loop-helix protein | 0.00777778 |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 | 0.00776818 |
| PGD | phosphogluconate dehydrogenase | 0.00776373 |
| GALNT1 | polypeptide N-acetylgalactosaminyltransferase 1 | 0.007752 |
| FCGBP | Fc fragment of IgG binding protein | 0.00774893 |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | 0.00774628 |
| BPGM | 2,3-bisphosphoglycerate mutase | 0.0077152 |
| ZC3H12A | zinc finger CCCH-type containing 12A | 0.00767906 |
| HMGA1 | high mobility group AT-hook 1 | 0.00763328 |
| CLDN7 | claudin 7 | 0.00762685 |
| ALDH5A1 | aldehyde dehydrogenase 5 family, member A1 | 0.00762611 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.00762501 |
| GMPR | guanosine monophosphate reductase | 0.00759848 |
| AUTS2 | autism susceptibility candidate 2 | 0.00759512 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | 0.00755173 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | 0.00754911 |
| CTSZ | cathepsin Z | 0.00752167 |
| GRAMD2B | GRAM domain containing 2B | 0.00751916 |
| OPTN | optineurin | 0.00751776 |
| DIPK1A | divergent protein kinase domain 1A | 0.00747982 |
| MARCH8 | membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase | 0.0074696 |
| MS4A3 | membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) | 0.00745897 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 | 0.00744157 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | 0.00744083 |
| LXN | latexin | 0.00742659 |
| KLK6 | kallikrein-related peptidase 6 | 0.00739663 |
| COL6A3 | collagen, type VI, alpha 3 | 0.00738633 |
| ASXL2 | additional sex combs like transcriptional regulator 2 | 0.00738377 |
| PIM1 | Pim-1 proto-oncogene, serine/threonine kinase | 0.00734952 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.00733898 |
| OLFM4 | olfactomedin 4 | 0.00731118 |
| KRT17 | keratin 17, type I | 0.00728948 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.00726146 |
| TNNT1 | troponin T type 1 (skeletal, slow) | 0.00723752 |
| JAK1 | Janus kinase 1 | 0.00722235 |
| ABHD4 | abhydrolase domain containing 4 | 0.00720629 |
| SCEL | sciellin | 0.00720209 |
| CAST | calpastatin | 0.00718295 |
| PLAU | plasminogen activator, urokinase | 0.00717432 |
| ABLIM1 | actin binding LIM protein 1 | 0.00714056 |
| MMP12 | matrix metallopeptidase 12 | 0.00713587 |
| LAMC2 | laminin, gamma 2 | 0.00713034 |
| CLCA4 | chloride channel accessory 4 | 0.00713013 |
| PAMR1 | peptidase domain containing associated with muscle regeneration 1 | 0.00711735 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | 0.00711402 |
| POU4F1 | POU class 4 homeobox 1 | 0.00711106 |
| ZBED2 | zinc finger, BED-type containing 2 | 0.00711041 |
| JAG1 | jagged 1 | 0.00710467 |
| OGFRL1 | opioid growth factor receptor-like 1 | 0.00709805 |
| ACTN1 | actinin, alpha 1 | 0.0070768 |
| FPR1 | formyl peptide receptor 1 | 0.00707463 |
| GALNT3 | polypeptide N-acetylgalactosaminyltransferase 3 | 0.00706356 |
| AK1 | adenylate kinase 1 | 0.00705955 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | 0.00704846 |
| SULF1 | sulfatase 1 | 0.00704364 |
| ANXA3 | annexin A3 | 0.00704164 |
| CA8 | carbonic anhydrase VIII | 0.00702012 |
| RRAS | related RAS viral (r-ras) oncogene homolog | 0.00701667 |
| IFRD1 | interferon-related developmental regulator 1 | 0.00700415 |
| CAMP | cathelicidin antimicrobial peptide | 0.00700071 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.00699848 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | 0.00694767 |
| MED22 | mediator complex subunit 22 | 0.00693174 |
| DOK5 | docking protein 5 | 0.00693001 |
| CHGB | chromogranin B | 0.00691386 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 | 0.00690554 |
| SELL | selectin L | 0.00688055 |
| PERP | PERP, TP53 apoptosis effector | 0.00687791 |
| HIST1H2BD | histone cluster 1, H2bd | 0.00687309 |
| HBD | hemoglobin, delta | 0.00686813 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | 0.00685689 |
| STEAP1 | six transmembrane epithelial antigen of the prostate 1 | 0.0068407 |
| CEBPG | CCAAT/enhancer binding protein (C/EBP), gamma | 0.00683046 |
| STX8 | syntaxin 8 | 0.0068272 |
| FERMT1 | fermitin family member 1 | 0.00681735 |
| RTN2 | reticulon 2 | 0.00681441 |
| SLC14A1 | solute carrier family 14 (urea transporter), member 1 (Kidd blood group) | 0.00681426 |
| FGFBP1 | fibroblast growth factor binding protein 1 | 0.00679543 |
| GJA1 | gap junction protein, alpha 1, 43kDa | 0.00673267 |
| CD59 | CD59 molecule, complement regulatory protein | 0.0067284 |
| MMP9 | matrix metallopeptidase 9 | 0.00672675 |
| MSLN | mesothelin | 0.00668067 |
| NFIL3 | nuclear factor, interleukin 3 regulated | 0.00666385 |
| SARS1 | seryl-tRNA synthetase 1 | 0.00664731 |
| UPP1 | uridine phosphorylase 1 | 0.00663948 |
| JMJD6 | jumonji domain containing 6 | 0.00662483 |
| ZNF331 | zinc finger protein 331 | 0.00662087 |
| NCF2 | neutrophil cytosolic factor 2 | 0.00661742 |
| CEACAM7 | carcinoembryonic antigen-related cell adhesion molecule 7 | 0.00661468 |
| SELENBP1 | selenium binding protein 1 | 0.00659892 |
| PPP1R13L | protein phosphatase 1, regulatory subunit 13 like | 0.00658905 |
| SERPINB8 | serpin peptidase inhibitor, clade B (ovalbumin), member 8 | 0.00656738 |
| GPX1 | glutathione peroxidase 1 | 0.00655052 |
| EPS8L1 | EPS8-like 1 | 0.00654897 |
| YPEL5 | yippee-like 5 (Drosophila) | 0.00654489 |
| KLK13 | kallikrein-related peptidase 13 | 0.00653931 |
| CRCT1 | cysteine-rich C-terminal 1 | 0.00652924 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | 0.00652656 |
| TENM4 | teneurin transmembrane protein 4 | 0.00650397 |
| STK38 | serine/threonine kinase 38 | 0.00648812 |
| TMPRSS11E | transmembrane protease, serine 11E | 0.00648301 |
| MMP19 | matrix metallopeptidase 19 | 0.00646386 |
| NCF4 | neutrophil cytosolic factor 4, 40kDa | 0.00646135 |
| ASS1 | argininosuccinate synthase 1 | 0.00645073 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.00645067 |
| PEG10 | paternally expressed 10 | 0.0064426 |
| SIRT3 | sirtuin 3 | 0.00638683 |
| GLIPR1 | GLI pathogenesis-related 1 | 0.00638473 |
| TPST2 | tyrosylprotein sulfotransferase 2 | 0.00637044 |
| ACOX1 | acyl-CoA oxidase 1, palmitoyl | 0.00636923 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.00636187 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -0.0194995 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -0.0158825 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -0.0152195 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | -0.0142293 |
| REEP1 | receptor accessory protein 1 | -0.0138376 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | -0.0134134 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | -0.0134043 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 | -0.0128426 |
| TMSB15A | thymosin beta 15a | -0.0121964 |
| METTL7A | methyltransferase like 7A | -0.0120344 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 | -0.0119531 |
| BCHE | butyrylcholinesterase | -0.011681 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 | -0.0116221 |
| NID1 | nidogen 1 | -0.0116102 |
| CCL19 | chemokine (C-C motif) ligand 19 | -0.0114971 |
| CD36 | CD36 molecule (thrombospondin receptor) | -0.0114673 |
| SNX10 | sorting nexin 10 | -0.0114313 |
| PROM1 | prominin 1 | -0.0113695 |
| APOA1 | apolipoprotein A-I | -0.0112087 |
| DCLK1 | doublecortin-like kinase 1 | -0.0111679 |
| RAPGEF5 | Rap guanine nucleotide exchange factor (GEF) 5 | -0.0110487 |
| GNA11 | guanine nucleotide binding protein (G protein), alpha 11 (Gq class) | -0.0110418 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.0108568 |
| CHN2 | chimerin 2 | -0.0107761 |
| DEGS1 | delta(4)-desaturase, sphingolipid 1 | -0.0107484 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0107234 |
| GSTT1 | glutathione S-transferase theta 1 | -0.0106827 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0104683 |
| IMPA2 | inositol(myo)-1(or 4)-monophosphatase 2 | -0.0104534 |
| HELLS | helicase, lymphoid-specific | -0.0103978 |
| APOB | apolipoprotein B | -0.0103457 |
| TOX3 | TOX high mobility group box family member 3 | -0.0102324 |
| LYZ | lysozyme | -0.0102087 |
| ANKRD10 | ankyrin repeat domain 10 | -0.00993002 |
| CRIP2 | cysteine-rich protein 2 | -0.00985354 |
| CA2 | carbonic anhydrase II | -0.00978557 |
| CYP2B6 | cytochrome P450, family 2, subfamily B, polypeptide 6 | -0.00975428 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.00971194 |
| SEPTIN10 | septin 10 | -0.00958947 |
| C4BPA | complement component 4 binding protein, alpha | -0.0095701 |
| MGP | matrix Gla protein | -0.00955058 |
| CADM1 | cell adhesion molecule 1 | -0.00954281 |
| MPZL2 | myelin protein zero-like 2 | -0.00945407 |
| FGF13 | fibroblast growth factor 13 | -0.00943931 |
| PRDX2 | peroxiredoxin 2 | -0.00929472 |
| ITPRID2 | ITPR interacting domain containing 2 | -0.00919427 |
| SPINK2 | serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) | -0.00913718 |
| CST3 | cystatin C | -0.00912709 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase | -0.00912449 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | -0.00911039 |
| FAM13A | family with sequence similarity 13, member A | -0.00893595 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.00891719 |
| NRGN | neurogranin (protein kinase C substrate, RC3) | -0.00888555 |
| SPARCL1 | SPARC-like 1 (hevin) | -0.00886988 |
| NVL | nuclear VCP-like | -0.00882685 |
| DMD | dystrophin | -0.00877345 |
| REV1 | REV1, polymerase (DNA directed) | -0.00869577 |
| TDO2 | tryptophan 2,3-dioxygenase | -0.00866042 |
| ADGRF5 | adhesion G protein-coupled receptor F5 | -0.00864146 |
| UGT2A3 | UDP glucuronosyltransferase 2 family, polypeptide A3 | -0.00859893 |
| SFTPC | surfactant protein C | -0.00858196 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.00857511 |
| RTN1 | reticulon 1 | -0.00855221 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | -0.00854635 |
| APOA2 | apolipoprotein A-II | -0.00849645 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.00844214 |
| FGL2 | fibrinogen-like 2 | -0.00843912 |
| C7 | complement component 7 | -0.00842874 |
| SECTM1 | secreted and transmembrane 1 | -0.00839111 |
| CLEC2B | C-type lectin domain family 2, member B | -0.00837887 |
| GPC3 | glypican 3 | -0.00834625 |
| RBPMS | RNA binding protein with multiple splicing | -0.00831086 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.00828032 |
| BAD | BCL2-associated agonist of cell death | -0.00827507 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.00819145 |
| ADCY9 | adenylate cyclase 9 | -0.00806875 |
| TXNIP | thioredoxin interacting protein | -0.00803537 |
| KDM5D | lysine (K)-specific demethylase 5D | -0.00802171 |
| SERPIND1 | serpin peptidase inhibitor, clade D (heparin cofactor), member 1 | -0.00800562 |
| GNAO1 | guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O | -0.00799659 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | -0.00799637 |
| AOC3 | amine oxidase, copper containing 3 | -0.00799058 |
| LAMP5 | lysosomal-associated membrane protein family, member 5 | -0.00798919 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.00795371 |
| CP | ceruloplasmin (ferroxidase) | -0.00795257 |
| EPCAM | epithelial cell adhesion molecule | -0.00793779 |
| ATP5ME | ATP synthase membrane subunit e | -0.00790862 |
| SDF4 | stromal cell derived factor 4 | -0.00788219 |
| ABCA8 | ATP-binding cassette, sub-family A (ABC1), member 8 | -0.00786078 |
| MT1M | metallothionein 1M | -0.00780945 |
| FZD5 | frizzled class receptor 5 | -0.00777329 |
| TMEM165 | transmembrane protein 165 | -0.00777084 |
| COL15A1 | collagen, type XV, alpha 1 | -0.00776952 |
| NPY1R | neuropeptide Y receptor Y1 | -0.00775417 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.00774293 |
| ABCG1 | ATP-binding cassette, sub-family G (WHITE), member 1 | -0.00770466 |
| CFH | complement factor H | -0.00768015 |
| SLC37A4 | solute carrier family 37 (glucose-6-phosphate transporter), member 4 | -0.00767594 |
| NPTX2 | neuronal pentraxin II | -0.00766826 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.00766652 |
| HNRNPL | heterogeneous nuclear ribonucleoprotein L | -0.00763214 |
| ARL5A | ADP-ribosylation factor-like 5A | -0.00763029 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | -0.00760094 |
| SPRY4 | sprouty homolog 4 (Drosophila) | -0.00759093 |
| HABP2 | hyaluronan binding protein 2 | -0.00758615 |
| SH3BGRL | SH3 domain binding glutamate-rich protein like | -0.00757751 |
| LMO3 | LIM domain only 3 (rhombotin-like 2) | -0.00757672 |
| ENPEP | glutamyl aminopeptidase (aminopeptidase A) | -0.00756306 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.00755945 |
| ZNF160 | zinc finger protein 160 | -0.00755188 |
| SEPP1 | selenoprotein P, plasma, 1 | -0.00755188 |
| FABP1 | fatty acid binding protein 1, liver | -0.00752801 |
| KCND3 | potassium channel, voltage gated Shal related subfamily D, member 3 | -0.00750848 |
| FBXO11 | F-box protein 11 | -0.00750463 |
| ITGA7 | integrin, alpha 7 | -0.00749573 |
| FOXF1 | forkhead box F1 | -0.00749093 |
| NMU | neuromedin U | -0.00748157 |
| MT1E | metallothionein 1E | -0.00744142 |
| PRR11 | proline rich 11 | -0.00743413 |
| MTUS1 | microtubule associated tumor suppressor 1 | -0.00740839 |
| UGT2B15 | UDP glucuronosyltransferase 2 family, polypeptide B15 | -0.00740649 |
| SUB1 | SUB1 homolog (S. cerevisiae) | -0.00738751 |
| OSMR | oncostatin M receptor | -0.00737945 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.00735351 |
| FZD6 | frizzled class receptor 6 | -0.0073389 |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) | -0.00731747 |
| BST2 | bone marrow stromal cell antigen 2 | -0.00730021 |
| CTSH | cathepsin H | -0.0072739 |
| HAUS2 | HAUS augmin-like complex, subunit 2 | -0.00726388 |
| LAMA4 | laminin, alpha 4 | -0.00725972 |
| APOC3 | apolipoprotein C-III | -0.00725896 |
| SERPINA7 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7 | -0.00725775 |
| MCAM | melanoma cell adhesion molecule | -0.00725617 |
| LDOC1 | leucine zipper, down-regulated in cancer 1 | -0.00725533 |
| PDLIM3 | PDZ and LIM domain 3 | -0.00722837 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | -0.0071828 |
| PHTF2 | putative homeodomain transcription factor 2 | -0.00715846 |
| DHFR | dihydrofolate reductase | -0.00715626 |
| NPM3 | nucleophosmin/nucleoplasmin 3 | -0.00714131 |
| PRKCZ | protein kinase C, zeta | -0.00712342 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | -0.00710512 |
| CBX3 | chromobox homolog 3 | -0.00708483 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | -0.00708376 |
| MBL2 | mannose-binding lectin (protein C) 2, soluble | -0.00706494 |
| ATP5F1D | ATP synthase F1 subunit delta | -0.00706193 |
| ADAMTSL3 | ADAMTS-like 3 | -0.00706171 |
| CREBZF | CREB/ATF bZIP transcription factor | -0.00705393 |
| LMO2 | LIM domain only 2 (rhombotin-like 1) | -0.00705069 |
| CAMKK2 | calcium/calmodulin-dependent protein kinase kinase 2, beta | -0.00699814 |
| FRZB | frizzled-related protein | -0.00698991 |
| CPM | carboxypeptidase M | -0.00697798 |
| CPB1 | carboxypeptidase B1 (tissue) | -0.00696366 |
| ZNF721 | zinc finger protein 721 | -0.00693161 |
| SCRG1 | stimulator of chondrogenesis 1 | -0.0069148 |
| CTBP1 | C-terminal binding protein 1 | -0.00689253 |
| SCAF4 | SR-related CTD-associated factor 4 | -0.0068684 |
| KLHL23 | kelch-like family member 23 | -0.00686803 |
| YTHDC2 | YTH domain containing 2 | -0.00684533 |
| FAM120A | family with sequence similarity 120A | -0.00684524 |
| AHSG | alpha-2-HS-glycoprotein | -0.00684343 |
| RARRES3 | retinoic acid receptor responder (tazarotene induced) 3 | -0.00683465 |
| ABHD3 | abhydrolase domain containing 3 | -0.00681901 |
| RXRA | retinoid X receptor, alpha | -0.00679263 |
| SPTSSA | serine palmitoyltransferase, small subunit A | -0.00679016 |
| RUFY3 | RUN and FYVE domain containing 3 | -0.00678388 |
| GANAB | glucosidase, alpha; neutral AB | -0.00677646 |
| RGS5 | regulator of G-protein signaling 5 | -0.00676753 |
| KCNS3 | potassium voltage-gated channel, modifier subfamily S, member 3 | -0.00676669 |
| COL4A2 | collagen, type IV, alpha 2 | -0.00675951 |
| MGRN1 | mahogunin ring finger 1, E3 ubiquitin protein ligase | -0.00675745 |
| ECI1 | enoyl-CoA delta isomerase 1 | -0.00671316 |
| FLRT3 | fibronectin leucine rich transmembrane protein 3 | -0.00670908 |
| GNG10 | guanine nucleotide binding protein (G protein), gamma 10 | -0.00667139 |
| KCNK3 | potassium channel, two pore domain subfamily K, member 3 | -0.00666477 |
| FRY | furry homolog (Drosophila) | -0.006638 |
| CPE | carboxypeptidase E | -0.00663193 |
| CCP110 | centriolar coiled coil protein 110kDa | -0.00662694 |
| SELENOW | selenoprotein W | -0.00662327 |
| SLC29A1 | solute carrier family 29 (equilibrative nucleoside transporter), member 1 | -0.00662238 |
| CPT1A | carnitine palmitoyltransferase 1A (liver) | -0.00661814 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | -0.00661442 |
| PSMD11 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 | -0.00660915 |
| SYBU | syntabulin (syntaxin-interacting) | -0.00660097 |
| VWA1 | von Willebrand factor A domain containing 1 | -0.00659597 |
| MZT2A | mitotic spindle organizing protein 2A | -0.00658249 |
| MELK | maternal embryonic leucine zipper kinase | -0.00655834 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 | -0.00654622 |
| KRT2 | keratin 2, type II | -0.00654378 |
| FBXW12 | F-box and WD repeat domain containing 12 | -0.00654324 |
| TNS3 | tensin 3 | -0.00653852 |
| ERBB3 | erb-b2 receptor tyrosine kinase 3 | -0.00652659 |
| SLCO3A1 | solute carrier organic anion transporter family, member 3A1 | -0.00651917 |
| SCAND1 | SCAN domain containing 1 | -0.00651906 |
| CPVL | carboxypeptidase, vitellogenic-like | -0.00645815 |
| TSPAN12 | tetraspanin 12 | -0.00645738 |
| GET1 | guided entry of tail-anchored proteins factor 1 | -0.00644366 |
| ABHD17A | abhydrolase domain containing 17A | -0.00643436 |
| MAP3K7CL | MAP3K7 C-terminal like | -0.00643065 |
| CILP | cartilage intermediate layer protein, nucleotide pyrophosphohydrolase | -0.00641331 |
| SLBP | stem-loop binding protein | -0.00640339 |
| EDRF1 | erythroid differentiation regulatory factor 1 | -0.0063978 |
| PBLD | phenazine biosynthesis-like protein domain containing | -0.00637594 |
| CALCA | calcitonin-related polypeptide alpha | -0.0063602 |
| RAB20 | RAB20, member RAS oncogene family | -0.0063562 |
| FKBP1B | FK506 binding protein 1B, 12.6 kDa | -0.00634878 |
| FMO5 | flavin containing monooxygenase 5 | -0.00634854 |
| PCLAF | PCNA clamp associated factor | -0.00634699 |
| RCAN2 | regulator of calcineurin 2 | -0.00634175 |
| NAAA | N-acylethanolamine acid amidase | -0.00632336 |
| MGST2 | microsomal glutathione S-transferase 2 | -0.00631575 |
| HMGN5 | high mobility group nucleosome binding domain 5 | -0.0063113 |
| PIEZO2 | piezo-type mechanosensitive ion channel component 2 | -0.00629222 |
| NLGN4X | neuroligin 4, X-linked | -0.00627782 |
| MTTP | microsomal triglyceride transfer protein | -0.00627115 |
| NR0B2 | nuclear receptor subfamily 0, group B, member 2 | -0.00626979 |
| FGG | fibrinogen gamma chain | -0.00624654 |
| ETV5 | ets variant 5 | -0.00624637 |
| SFTPD | surfactant protein D | -0.00624123 |
| APOD | apolipoprotein D | -0.0062408 |
| COL3A1 | collagen, type III, alpha 1 | -0.0062366 |
| SLC25A6 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 | -0.00622583 |
| PCGF3 | polycomb group ring finger 3 | -0.00621844 |
| DMBT1 | deleted in malignant brain tumors 1 | -0.00621822 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | -0.00621121 |
| ADH1B | alcohol dehydrogenase 1B (class I), beta polypeptide | -0.00620118 |
| EIF5A | eukaryotic translation initiation factor 5A | -0.00618608 |
| MYH11 | myosin, heavy chain 11, smooth muscle | -0.00617118 |
| PPAP2A | phosphatidic acid phosphatase type 2A | -0.00615593 |
| PTP4A3 | protein tyrosine phosphatase type IVA, member 3 | -0.00615535 |
| TIA1 | TIA1 cytotoxic granule-associated RNA binding protein | -0.00614582 |
| CDCA4 | cell division cycle associated 4 | -0.00614248 |
| COL6A2 | collagen, type VI, alpha 2 | -0.00614023 |
| HMGB3 | high mobility group box 3 | -0.00610689 |
| COX6C | cytochrome c oxidase subunit VIc | -0.00608555 |
| RAD21 | RAD21 homolog (S. pombe) | -0.00608362 |
| AGPAT5 | 1-acylglycerol-3-phosphate O-acyltransferase 5 | -0.00604853 |
| PLK1 | polo-like kinase 1 | -0.0060345 |
| RPA3 | replication protein A3, 14kDa | -0.00603441 |
| DAPK1 | death-associated protein kinase 1 | -0.00602596 |
| CDS1 | CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1 | -0.00602367 |
| TLE5 | TLE family member 5, transcriptional modulator | -0.00601907 |
| NETO2 | neuropilin (NRP) and tolloid (TLL)-like 2 | -0.00601444 |
| RNH1 | ribonuclease/angiogenin inhibitor 1 | -0.00595823 |
| PLN | phospholamban | -0.00595178 |
| WWP1 | WW domain containing E3 ubiquitin protein ligase 1 | -0.0059479 |
| NOTCH2NL | notch 2 N-terminal like | -0.00594749 |
| E2F8 | E2F transcription factor 8 | -0.00590905 |
| H2AX | H2A.X variant histone | -0.00589338 |
| TSPAN13 | tetraspanin 13 | -0.00589337 |
| MAOA | monoamine oxidase A | -0.00589021 |
