C1S Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description complement component 1, s subcomponent|This gene encodes a serine protease, which is a major constituent of the human complement subcomponent C1. C1s associates with two other complement components C1r and C1q in order to yield the first component of the serum complement system. Defects in this gene are the cause of selective C1s deficiency. [provided by RefSeq, Mar 2009] (NCBI Entrez Gene Database, 716)
External Link http://www.ncbi.nlm.nih.gov/gene/716
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Genes

91 interacting proteins for C1S from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
A1BG alpha-1-B glycoprotein
A2M alpha-2-macroglobulin
AHSG alpha-2-HS-glycoprotein
ALB albumin
AMBP alpha-1-microglobulin/bikunin precursor
APCS amyloid P component, serum
APOA1 apolipoprotein A-I
APOA2 apolipoprotein A-II
APOA4 apolipoprotein A-IV
APOC1 apolipoprotein C-I
APOC2 apolipoprotein C-II
APOC3 apolipoprotein C-III
APOE apolipoprotein E
APOM apolipoprotein M
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
C1QA complement component 1, q subcomponent, A chain
C1QB complement component 1, q subcomponent, B chain
C1QC complement component 1, q subcomponent, C chain
C1R complement component 1, r subcomponent
C2 complement component 2
C3 complement component 3
C4A complement component 4A (Rodgers blood group)
C4B complement component 4B (Chido blood group)
C4BPA complement component 4 binding protein, alpha
C4BPB complement component 4 binding protein, beta
C6 complement component 6
C9 complement component 9
CD5L CD5 molecule-like
CFB complement factor B
CFH complement factor H
CLU clusterin
COL6A6 collagen, type VI, alpha 6
CP ceruloplasmin (ferroxidase)
CRP C-reactive protein, pentraxin-related
DNA2 DNA replication helicase/nuclease 2
DUOX1 dual oxidase 1
EPYC epiphycan
F2 coagulation factor II (thrombin)
FGA fibrinogen alpha chain
FGB fibrinogen beta chain
FGG fibrinogen gamma chain
FN1 fibronectin 1
GC group-specific component (vitamin D binding protein)
GCC2 GRIP and coiled-coil domain containing 2
HNF1A HNF1 homeobox A
HNF4A hepatocyte nuclear factor 4, alpha
HP haptoglobin
HPR haptoglobin-related protein
HRG histidine-rich glycoprotein
IGFALS insulin-like growth factor binding protein, acid labile subunit
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
IGHG2 immunoglobulin heavy constant gamma 2 (G2m marker)
IGHG3 immunoglobulin heavy constant gamma 3 (G3m marker)
IGHG4 immunoglobulin heavy constant gamma 4 (G4m marker)
IGKC immunoglobulin kappa constant
IGKV1-5 immunoglobulin kappa variable 1-5
IGKV4-1 immunoglobulin kappa variable 4-1
IGLC1 immunoglobulin lambda constant 1 (Mcg marker)
IGLC2 immunoglobulin lambda constant 2 (Kern-Oz- marker)
IGLC3 immunoglobulin lambda constant 3 (Kern-Oz+ marker)
IGLC6 immunoglobulin lambda constant 6 (Kern+Oz- marker, gene/pseudogene)
IGLL5 immunoglobulin lambda-like polypeptide 5
ITIH1 inter-alpha-trypsin inhibitor heavy chain 1
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2
ITIH4 inter-alpha-trypsin inhibitor heavy chain family, member 4
KIAA0753 KIAA0753
KIRREL kin of IRRE like (Drosophila)
KLC1 kinesin light chain 1
KNG1 kininogen 1
LBP lipopolysaccharide binding protein
LUM lumican
ONECUT1 one cut homeobox 1
OPTN optineurin
ORM2 orosomucoid 2
PLG plasminogen
PON1 paraoxonase 1
PON3 paraoxonase 3
PROS1 protein S (alpha)
PTX3 pentraxin 3, long
SAA2 serum amyloid A2
SAA4 serum amyloid A4, constitutive
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPIND1 serpin peptidase inhibitor, clade D (heparin cofactor), member 1
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
SHBG sex hormone-binding globulin
SPTLC2 serine palmitoyltransferase, long chain base subunit 2
TRIM33 tripartite motif containing 33
TTR transthyretin
UBE2L3 ubiquitin-conjugating enzyme E2L 3
VKORC1 vitamin K epoxide reductase complex, subunit 1
VTN vitronectin