| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | complement component 4A (Rodgers blood group)|This gene encodes the acidic form of complement factor 4, part of the classical activation pathway. The protein is expressed as a single chain precursor which is proteolytically cleaved into a trimer of alpha, beta, and gamma chains prior to secretion. The trimer provides a surface for interaction between the antigen-antibody complex and other complement components. The alpha chain is cleaved to release C4 anaphylatoxin, an antimicrobial peptide and a mediator of local inflammation. Deficiency of this protein is associated with systemic lupus erythematosus and type I diabetes mellitus. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. Varying haplotypes of this gene cluster exist, such that individuals may have 1, 2, or 3 copies of this gene. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2014] (NCBI Entrez Gene Database, 720) |
| External Link | https://ncbi.nlm.nih.gov/gene/720 |
| Similar Terms | |
| Downloads & Tools |
498 genes differentially expressed following the C4A gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MAGEA3 | melanoma antigen family A3 | 0.0203803 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0132733 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) | 0.0119754 |
| PI3 | peptidase inhibitor 3, skin-derived | 0.0117792 |
| MAGEA12 | melanoma antigen family A12 | 0.0114851 |
| ATF3 | activating transcription factor 3 | 0.0110511 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0108687 |
| SPRR2B | small proline-rich protein 2B | 0.0108384 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.0105417 |
| ISG20 | interferon stimulated exonuclease gene 20kDa | 0.0105169 |
| SFN | stratifin | 0.0105163 |
| KRT14 | keratin 14, type I | 0.0103083 |
| ASS1 | argininosuccinate synthase 1 | 0.0102609 |
| S100A7 | S100 calcium binding protein A7 | 0.0102561 |
| DEFB1 | defensin, beta 1 | 0.010244 |
| TMEM176B | transmembrane protein 176B | 0.00999866 |
| TSPAN8 | tetraspanin 8 | 0.00993843 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.00968969 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | 0.00963048 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | 0.00930361 |
| WASHC4 | WASH complex subunit 4 | 0.00923716 |
| F2RL1 | coagulation factor II (thrombin) receptor-like 1 | 0.00907249 |
| MAGEA1 | melanoma antigen family A1 | 0.00905859 |
| CALB1 | calbindin 1, 28kDa | 0.00905169 |
| CLTB | clathrin, light chain B | 0.00904264 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | 0.00903425 |
| TMEM176A | transmembrane protein 176A | 0.00886383 |
| KLK10 | kallikrein-related peptidase 10 | 0.00878684 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.00876497 |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) | 0.00871715 |
| ADM | adrenomedullin | 0.00869573 |
| TRIM29 | tripartite motif containing 29 | 0.00868092 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.00867964 |
| MTUS1 | microtubule associated tumor suppressor 1 | 0.00856167 |
| EFNA1 | ephrin-A1 | 0.00850074 |
| ABCG2 | ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) | 0.00849758 |
| GBP2 | guanylate binding protein 2, interferon-inducible | 0.00848369 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.00844649 |
| S100P | S100 calcium binding protein P | 0.00842806 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.00837363 |
| LY6D | lymphocyte antigen 6 complex, locus D | 0.00831275 |
| GPX2 | glutathione peroxidase 2 | 0.00829189 |
| KRT6A | keratin 6A, type II | 0.00812295 |
| SPRR3 | small proline-rich protein 3 | 0.00807027 |
| PRDX1 | peroxiredoxin 1 | 0.00800644 |
| KDM5D | lysine (K)-specific demethylase 5D | 0.00797739 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.00795666 |
| SLPI | secretory leukocyte peptidase inhibitor | 0.0079242 |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 | 0.00787623 |
| POSTN | periostin, osteoblast specific factor | 0.00786151 |
| MAL | mal, T-cell differentiation protein | 0.00783363 |
| EMP1 | epithelial membrane protein 1 | 0.00781235 |
| ZNF395 | zinc finger protein 395 | 0.00778145 |
| LAMC2 | laminin, gamma 2 | 0.00776335 |
| MT1X | metallothionein 1X | 0.0077042 |
| CA12 | carbonic anhydrase XII | 0.00758914 |
| CDA | cytidine deaminase | 0.00757587 |
| LAMA2 | laminin, alpha 2 | 0.00754329 |
| JPT2 | Jupiter microtubule associated homolog 2 | 0.00754112 |
| COL3A1 | collagen, type III, alpha 1 | 0.00751823 |
| BPGM | 2,3-bisphosphoglycerate mutase | 0.00748772 |
| HMOX1 | heme oxygenase 1 | 0.00747736 |
| PALLD | palladin, cytoskeletal associated protein | 0.00746749 |
| IL32 | interleukin 32 | 0.00746092 |
| PSMD4 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 | 0.00735967 |
| COL1A2 | collagen, type I, alpha 2 | 0.00733793 |
| SLC7A7 | solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 | 0.00733471 |
| SPRR1B | small proline-rich protein 1B | 0.0073347 |
| SPRR1A | small proline-rich protein 1A | 0.0073208 |
| KRT17 | keratin 17, type I | 0.00727193 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.00725218 |
| MKNK1 | MAP kinase interacting serine/threonine kinase 1 | 0.00721514 |
| HEY1 | hes-related family bHLH transcription factor with YRPW motif 1 | 0.00718775 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | 0.00718479 |
| KRT16 | keratin 16, type I | 0.00714807 |
| FERMT1 | fermitin family member 1 | 0.00708258 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | 0.00702496 |
| LGALS4 | lectin, galactoside-binding, soluble, 4 | 0.00701637 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | 0.00700659 |
| S100A10 | S100 calcium binding protein A10 | 0.00698886 |
| PTHLH | parathyroid hormone-like hormone | 0.00697505 |
| RFTN1 | raftlin, lipid raft linker 1 | 0.00694718 |
| HSPA1A | heat shock 70kDa protein 1A | 0.00694085 |
| HSPA2 | heat shock 70kDa protein 2 | 0.0069403 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 0.0069243 |
| LY96 | lymphocyte antigen 96 | 0.00690152 |
| KRT6B | keratin 6B, type II | 0.00686356 |
| MYRF | myelin regulatory factor | 0.00683474 |
| IL1R2 | interleukin 1 receptor, type II | 0.00682407 |
| AOC1 | amine oxidase, copper containing 1 | 0.00681625 |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') | 0.00679676 |
| DSG3 | desmoglein 3 | 0.00679005 |
| ADAMTS5 | ADAM metallopeptidase with thrombospondin type 1 motif, 5 | 0.00678793 |
| KLK13 | kallikrein-related peptidase 13 | 0.00676042 |
| ABLIM1 | actin binding LIM protein 1 | 0.0067368 |
| FOXO1 | forkhead box O1 | 0.00671763 |
| IL15RA | interleukin 15 receptor, alpha | 0.00671691 |
| TP53I3 | tumor protein p53 inducible protein 3 | 0.00671444 |
| COL5A2 | collagen, type V, alpha 2 | 0.00669257 |
| CD53 | CD53 molecule | 0.00668624 |
| PIM1 | Pim-1 proto-oncogene, serine/threonine kinase | 0.00667161 |
| SSX1 | synovial sarcoma, X breakpoint 1 | 0.00665867 |
| CNTN1 | contactin 1 | 0.00665133 |
| ETHE1 | ethylmalonic encephalopathy 1 | 0.00664655 |
| CD163 | CD163 molecule | 0.0066363 |
| C1QB | complement component 1, q subcomponent, B chain | 0.0066199 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.00657889 |
| ATF4 | activating transcription factor 4 | 0.00656522 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | 0.00655267 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F | 0.00653393 |
| MVP | major vault protein | 0.00644635 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | 0.00643974 |
| ARL14 | ADP-ribosylation factor-like 14 | 0.00643114 |
| ZNF706 | zinc finger protein 706 | 0.0064293 |
| FGFBP1 | fibroblast growth factor binding protein 1 | 0.00639409 |
| MMP19 | matrix metallopeptidase 19 | 0.00635407 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.00633815 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.00633594 |
| RHCG | Rh family, C glycoprotein | 0.00633012 |
| ANXA2P2 | annexin A2 pseudogene 2 | 0.0063124 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | 0.00630941 |
| MT2A | metallothionein 2A | 0.00630521 |
| CSRP2 | cysteine and glycine-rich protein 2 | 0.00622062 |
| DSP | desmoplakin | 0.00618655 |
| RHOF | ras homolog family member F (in filopodia) | 0.0061566 |
| KRT19 | keratin 19, type I | 0.00614926 |
| TUBB2A | tubulin, beta 2A class IIa | 0.00614521 |
| BIK | BCL2-interacting killer (apoptosis-inducing) | 0.00612809 |
| UPP1 | uridine phosphorylase 1 | 0.00612358 |
| GATA6 | GATA binding protein 6 | 0.00611506 |
| CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 | 0.0061148 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.00611057 |
| HIST1H2AC | histone cluster 1, H2ac | 0.00607796 |
| S100A2 | S100 calcium binding protein A2 | 0.0060563 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | 0.00604799 |
| XPO7 | exportin 7 | 0.00602548 |
| CLEC2B | C-type lectin domain family 2, member B | 0.00601682 |
| PLIN3 | perilipin 3 | 0.00600454 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | 0.00600267 |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 | 0.00597704 |
| PARP12 | poly (ADP-ribose) polymerase family, member 12 | 0.00597501 |
| ADH5 | alcohol dehydrogenase 5 (class III), chi polypeptide | 0.00593548 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.00593033 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.00592615 |
| CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 | 0.00590457 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa | 0.00589664 |
| EGR2 | early growth response 2 | 0.00587986 |
| IFI44 | interferon-induced protein 44 | 0.00587913 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.00587904 |
| LAMB3 | laminin, beta 3 | 0.00587741 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 0.00586151 |
| GCH1 | GTP cyclohydrolase 1 | 0.00584902 |
| HBEGF | heparin-binding EGF-like growth factor | 0.00579763 |
| SATB2 | SATB homeobox 2 | 0.00577836 |
| TRIM16 | tripartite motif containing 16 | 0.00577353 |
| S100A11 | S100 calcium binding protein A11 | 0.00577038 |
| FGB | fibrinogen beta chain | 0.00576703 |
| HOXB7 | homeobox B7 | 0.00574075 |
| MRPL18 | mitochondrial ribosomal protein L18 | 0.00573707 |
| VDAC2 | voltage-dependent anion channel 2 | 0.00573313 |
| C1QA | complement component 1, q subcomponent, A chain | 0.00573155 |
| PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 | 0.00572191 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.00571653 |
| IL15 | interleukin 15 | 0.00571317 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.00568071 |
| TYMP | thymidine phosphorylase | 0.00568 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 0.0056535 |
| CCL20 | chemokine (C-C motif) ligand 20 | 0.00558407 |
| SCRG1 | stimulator of chondrogenesis 1 | 0.00555864 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | 0.00554662 |
| MT1HL1 | metallothionein 1H-like 1 | 0.00554583 |
| C1S | complement component 1, s subcomponent | 0.00552076 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | 0.00551775 |
| MAPK6 | mitogen-activated protein kinase 6 | 0.00550158 |
| S100A9 | S100 calcium binding protein A9 | 0.00546054 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming | 0.00545977 |
| POPDC3 | popeye domain containing 3 | 0.00545601 |
| RTP4 | receptor (chemosensory) transporter protein 4 | 0.00544166 |
| IPW | imprinted in Prader-Willi syndrome (non-protein coding) | 0.00543967 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.00543092 |
| KLF6 | Kruppel-like factor 6 | 0.00542686 |
| CST1 | cystatin SN | 0.00541204 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.00540696 |
| TDRD7 | tudor domain containing 7 | 0.00539512 |
| S100A14 | S100 calcium binding protein A14 | 0.00539016 |
| VNN1 | vanin 1 | 0.0053854 |
| KRT13 | keratin 13, type I | 0.00537748 |
| CRNN | cornulin | 0.0053499 |
| CD14 | CD14 molecule | 0.00534195 |
| CHPT1 | choline phosphotransferase 1 | 0.00531568 |
| OPTN | optineurin | 0.00530608 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 | 0.00529984 |
| EMC2 | ER membrane protein complex subunit 2 | 0.00528746 |
| TMEM100 | transmembrane protein 100 | 0.00528 |
| VSIG4 | V-set and immunoglobulin domain containing 4 | 0.00527068 |
| SELE | selectin E | 0.00525928 |
| KYNU | kynureninase | 0.00523467 |
| RGCC | regulator of cell cycle | 0.00523151 |
| IFI44L | interferon-induced protein 44-like | 0.00522704 |
| MYO1C | myosin IC | 0.00519845 |
| MT1H | metallothionein 1H | 0.00517991 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.00516168 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | 0.00516154 |
| PPIC | peptidylprolyl isomerase C (cyclophilin C) | 0.00514438 |
| DDIT3 | DNA-damage-inducible transcript 3 | 0.00514152 |
| C10ORF10 | chromosome 10 open reading frame 10 | 0.00513822 |
| ERP44 | endoplasmic reticulum protein 44 | 0.00512144 |
| UBE2L6 | ubiquitin-conjugating enzyme E2L 6 | 0.00512099 |
| TXN | thioredoxin | 0.00511553 |
| IFI35 | interferon-induced protein 35 | 0.00510181 |
| SLC35G2 | solute carrier family 35, member G2 | 0.00509256 |
| MUC13 | mucin 13, cell surface associated | 0.00508437 |
| FXYD3 | FXYD domain containing ion transport regulator 3 | 0.0050656 |
| MT1G | metallothionein 1G | 0.00505966 |
| GRK5 | G protein-coupled receptor kinase 5 | 0.00505505 |
| ELP3 | elongator acetyltransferase complex subunit 3 | 0.00504803 |
| NRCAM | neuronal cell adhesion molecule | 0.00504552 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.00504424 |
| CLDN10 | claudin 10 | 0.00504164 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 | 0.00503052 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | 0.00502984 |
| SLC31A2 | solute carrier family 31 (copper transporter), member 2 | 0.00502806 |
| TM4SF4 | transmembrane 4 L six family member 4 | 0.00502567 |
| SLC12A7 | solute carrier family 12 (potassium/chloride transporter), member 7 | 0.00501448 |
| HOMER1 | homer scaffolding protein 1 | 0.00501229 |
| FAR2 | fatty acyl CoA reductase 2 | 0.00499399 |
| SLC2A5 | solute carrier family 2 (facilitated glucose/fructose transporter), member 5 | 0.00499051 |
| TICAM1 | toll-like receptor adaptor molecule 1 | 0.00498713 |
| PODXL | podocalyxin-like | 0.00497759 |
| ANXA1 | annexin A1 | 0.00495471 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.00492648 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.00492291 |
| SNCAIP | synuclein, alpha interacting protein | 0.00490659 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.00490646 |
| ADA | adenosine deaminase | 0.00489743 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | 0.0048949 |
| TMPRSS4 | transmembrane protease, serine 4 | 0.00489085 |
| IGFBP6 | insulin-like growth factor binding protein 6 | 0.00489063 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 0.00488745 |
| SH3GLB1 | SH3-domain GRB2-like endophilin B1 | 0.00488245 |
| CFH | complement factor H | 0.0048691 |
| APOL2 | apolipoprotein L, 2 | 0.00485843 |
| OSR2 | odd-skipped related transciption factor 2 | 0.00485829 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.00484306 |
| BAG2 | BCL2-associated athanogene 2 | 0.00483776 |
| SMAD3 | SMAD family member 3 | 0.00483664 |
| BECN1 | beclin 1, autophagy related | 0.00483601 |
| CRCT1 | cysteine-rich C-terminal 1 | 0.00483594 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.00483173 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -0.0120625 |
| SMC1A | structural maintenance of chromosomes 1A | -0.0106833 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0105137 |
| GET1 | guided entry of tail-anchored proteins factor 1 | -0.0102579 |
| PCP4 | Purkinje cell protein 4 | -0.0100733 |
| TBC1D9 | TBC1 domain family, member 9 (with GRAM domain) | -0.00974567 |
| TM7SF2 | transmembrane 7 superfamily member 2 | -0.00920337 |
| XIC | X chromosome inactivation center | -0.00907191 |
| DEGS1 | delta(4)-desaturase, sphingolipid 1 | -0.00884729 |
| ESR1 | estrogen receptor 1 | -0.00870474 |
| RAPSN | receptor-associated protein of the synapse | -0.00866344 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | -0.00845959 |
| CPB1 | carboxypeptidase B1 (tissue) | -0.00836476 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) | -0.00819053 |
| TSPAN13 | tetraspanin 13 | -0.00813821 |
| TNC | tenascin C | -0.00808024 |
| LDOC1 | leucine zipper, down-regulated in cancer 1 | -0.00798208 |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta | -0.00796759 |
| AGTR1 | angiotensin II receptor, type 1 | -0.00790074 |
| FCER1A | Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide | -0.00785244 |
| DHCR24 | 24-dehydrocholesterol reductase | -0.00772038 |
| PRDX2 | peroxiredoxin 2 | -0.00765134 |
| DHCR7 | 7-dehydrocholesterol reductase | -0.00764452 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.00758795 |
| ADCY1 | adenylate cyclase 1 (brain) | -0.00756517 |
| CIT | citron rho-interacting serine/threonine kinase | -0.00743453 |
| IRX5 | iroquois homeobox 5 | -0.00737983 |
| QPCT | glutaminyl-peptide cyclotransferase | -0.00730731 |
| FASN | fatty acid synthase | -0.00724016 |
| CD36 | CD36 molecule (thrombospondin receptor) | -0.00720449 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.00710314 |
| HBD | hemoglobin, delta | -0.0070616 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.00704361 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.00703754 |
| MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 | -0.00696589 |
| APMAP | adipocyte plasma membrane associated protein | -0.00693659 |
| BEX1 | brain expressed, X-linked 1 | -0.00693175 |
| OLFM1 | olfactomedin 1 | -0.00690544 |
| CST3 | cystatin C | -0.00681093 |
| CD320 | CD320 molecule | -0.00676784 |
| LEF1 | lymphoid enhancer-binding factor 1 | -0.00673579 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.00673304 |
| TXLNA | taxilin alpha | -0.00672887 |
| RTN1 | reticulon 1 | -0.00665227 |
| DCLK1 | doublecortin-like kinase 1 | -0.00664984 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | -0.0066395 |
| MAP7 | microtubule-associated protein 7 | -0.00662783 |
| KCNS3 | potassium voltage-gated channel, modifier subfamily S, member 3 | -0.00661112 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.00658777 |
| CCL19 | chemokine (C-C motif) ligand 19 | -0.00650174 |
| TRIB2 | tribbles pseudokinase 2 | -0.00649424 |
| MLPH | melanophilin | -0.00647614 |
| MMP9 | matrix metallopeptidase 9 | -0.00642932 |
| HBB | hemoglobin, beta | -0.0063909 |
| EPHX1 | epoxide hydrolase 1, microsomal (xenobiotic) | -0.00636437 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | -0.0063512 |
| BANK1 | B-cell scaffold protein with ankyrin repeats 1 | -0.00632718 |
| DGKZ | diacylglycerol kinase, zeta | -0.00632704 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -0.00629968 |
| CPE | carboxypeptidase E | -0.00628688 |
| SNX10 | sorting nexin 10 | -0.0062604 |
| NOTCH2 | notch 2 | -0.00625959 |
| SLC39A6 | solute carrier family 39 (zinc transporter), member 6 | -0.00624451 |
| KAZN | kazrin, periplakin interacting protein | -0.0062331 |
| KCNK3 | potassium channel, two pore domain subfamily K, member 3 | -0.0062274 |
| SCUBE2 | signal peptide, CUB domain, EGF-like 2 | -0.00622452 |
| NEK2 | NIMA-related kinase 2 | -0.00621441 |
| FOXM1 | forkhead box M1 | -0.00619068 |
| H1-10 | H1.10 linker histone | -0.00617995 |
| PRRC2A | proline-rich coiled-coil 2A | -0.00617987 |
| SLC37A4 | solute carrier family 37 (glucose-6-phosphate transporter), member 4 | -0.00613549 |
| DEFA4 | defensin, alpha 4, corticostatin | -0.0061234 |
| NRGN | neurogranin (protein kinase C substrate, RC3) | -0.00609945 |
| CTBP1 | C-terminal binding protein 1 | -0.00608351 |
| ADGRF5 | adhesion G protein-coupled receptor F5 | -0.00605527 |
| WDR7 | WD repeat domain 7 | -0.00604038 |
| DNAJC12 | DnaJ (Hsp40) homolog, subfamily C, member 12 | -0.0060076 |
| CHRDL1 | chordin-like 1 | -0.00600299 |
| CXCL12 | chemokine (C-X-C motif) ligand 12 | -0.00597506 |
| SLC44A4 | solute carrier family 44, member 4 | -0.00595923 |
| OBSL1 | obscurin-like 1 | -0.00591773 |
| LEPR | leptin receptor | -0.00591724 |
| ZNF512B | zinc finger protein 512B | -0.00590137 |
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) | -0.00585534 |
| ITGA4 | integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) | -0.00581082 |
| CADPS2 | Ca++-dependent secretion activator 2 | -0.00580166 |
| C3ORF14 | chromosome 3 open reading frame 14 | -0.00576194 |
| GNAS | GNAS complex locus | -0.00574751 |
| RAB38 | RAB38, member RAS oncogene family | -0.00574532 |
| ELAPOR1 | endosome-lysosome associated apoptosis and autophagy regulator 1 | -0.00573049 |
| LYZ | lysozyme | -0.00572904 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | -0.00572079 |
| EIF5A | eukaryotic translation initiation factor 5A | -0.00570336 |
| CNN3 | calponin 3, acidic | -0.00566453 |
| PLEK | pleckstrin | -0.00562768 |
| HAUS3 | HAUS augmin-like complex, subunit 3 | -0.0056063 |
| CELSR2 | cadherin, EGF LAG seven-pass G-type receptor 2 | -0.00560274 |
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | -0.00557726 |
| ZBTB18 | zinc finger and BTB domain containing 18 | -0.00557603 |
| SRP9 | signal recognition particle 9kDa | -0.00557577 |
| RNPS1 | RNA binding protein S1, serine-rich domain | -0.00554925 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | -0.00552276 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.00551658 |
| PHACTR2 | phosphatase and actin regulator 2 | -0.00550052 |
| JCHAIN | joining chain of multimeric IgA and IgM | -0.00548075 |
| IDO1 | indoleamine 2,3-dioxygenase 1 | -0.00547927 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.00544402 |
| PLAT | plasminogen activator, tissue | -0.00543574 |
| TGFB1 | transforming growth factor, beta 1 | -0.00542651 |
| VARS | valyl-tRNA synthetase | -0.00537923 |
| CRYM | crystallin, mu | -0.00537063 |
| CNNM3 | cyclin and CBS domain divalent metal cation transport mediator 3 | -0.00533014 |
| SH3BGRL | SH3 domain binding glutamate-rich protein like | -0.00532537 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | -0.00532349 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.00531964 |
| FADS1 | fatty acid desaturase 1 | -0.00530962 |
| ALPL | alkaline phosphatase, liver/bone/kidney | -0.00529067 |
| NEFH | neurofilament, heavy polypeptide | -0.00528205 |
| LSM2 | LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -0.00528113 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | -0.00523887 |
| PDGFC | platelet derived growth factor C | -0.00521488 |
| GFRA1 | GDNF family receptor alpha 1 | -0.00520978 |
| TMSB15A | thymosin beta 15a | -0.00519149 |
| CEACAM8 | carcinoembryonic antigen-related cell adhesion molecule 8 | -0.00518913 |
| YKT6 | YKT6 v-SNARE homolog (S. cerevisiae) | -0.00517249 |
| ACAD8 | acyl-CoA dehydrogenase family, member 8 | -0.00516884 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.00516598 |
| NUMA1 | nuclear mitotic apparatus protein 1 | -0.00516539 |
| ADH1B | alcohol dehydrogenase 1B (class I), beta polypeptide | -0.00515636 |
| PF4 | platelet factor 4 | -0.00514687 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | -0.00513779 |
| STEAP3 | STEAP family member 3, metalloreductase | -0.00512982 |
| CCNB2 | cyclin B2 | -0.0051286 |
| CROCCP2 | ciliary rootlet coiled-coil, rootletin pseudogene 2 | -0.00511966 |
| IPO9 | importin 9 | -0.00510974 |
| KCND3 | potassium channel, voltage gated Shal related subfamily D, member 3 | -0.00510516 |
| CDS1 | CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1 | -0.00509547 |
| PCLO | piccolo presynaptic cytomatrix protein | -0.00509287 |
| DYNLL1 | dynein, light chain, LC8-type 1 | -0.00509144 |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha | -0.0050826 |
| NETO2 | neuropilin (NRP) and tolloid (TLL)-like 2 | -0.00506861 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | -0.00506644 |
| TPSAB1 | tryptase alpha/beta 1 | -0.00505543 |
| ORC1 | origin recognition complex, subunit 1 | -0.00505166 |
| NVL | nuclear VCP-like | -0.00504691 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | -0.00502719 |
| RRAGA | Ras-related GTP binding A | -0.00502509 |
| PGC | progastricsin (pepsinogen C) | -0.00502191 |
| TRMT5 | tRNA methyltransferase 5 | -0.00501759 |
| FABP4 | fatty acid binding protein 4, adipocyte | -0.00501505 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | -0.00500339 |
| INSIG1 | insulin induced gene 1 | -0.00499948 |
| GRIA2 | glutamate receptor, ionotropic, AMPA 2 | -0.00499736 |
| EHMT2 | euchromatic histone-lysine N-methyltransferase 2 | -0.00499566 |
| HIPK1 | homeodomain interacting protein kinase 1 | -0.00499367 |
| TSPYL1 | TSPY-like 1 | -0.00498859 |
| HELLS | helicase, lymphoid-specific | -0.00498348 |
| BSCL2 | Berardinelli-Seip congenital lipodystrophy 2 (seipin) | -0.00496724 |
| FGFR3 | fibroblast growth factor receptor 3 | -0.00496677 |
| DACH1 | dachshund family transcription factor 1 | -0.00495277 |
| NPY1R | neuropeptide Y receptor Y1 | -0.00495042 |
| NAV2 | neuron navigator 2 | -0.00493108 |
| CELSR1 | cadherin, EGF LAG seven-pass G-type receptor 1 | -0.00490686 |
| CRIP2 | cysteine-rich protein 2 | -0.00489181 |
| TSPYL5 | TSPY-like 5 | -0.00488597 |
| SELL | selectin L | -0.00488222 |
| DEAF1 | DEAF1 transcription factor | -0.00488183 |
| KIAA0513 | KIAA0513 | -0.00487751 |
| HCRT | hypocretin (orexin) neuropeptide precursor | -0.00486831 |
| SFTPD | surfactant protein D | -0.00486661 |
| TTC39A | tetratricopeptide repeat domain 39A | -0.00486044 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.00483647 |
| CCNF | cyclin F | -0.00483597 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.00483176 |
| RNASE2 | ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) | -0.00481049 |
| AHSP | alpha hemoglobin stabilizing protein | -0.0048053 |
| CAMP | cathelicidin antimicrobial peptide | -0.00479926 |
| PCSK1N | proprotein convertase subtilisin/kexin type 1 inhibitor | -0.00479728 |
| PPP1R1A | protein phosphatase 1, regulatory (inhibitor) subunit 1A | -0.00478247 |
| ABCA2 | ATP-binding cassette, sub-family A (ABC1), member 2 | -0.00478088 |
| PID1 | phosphotyrosine interaction domain containing 1 | -0.0047771 |
| TMEM14B | transmembrane protein 14B | -0.00476465 |
| LXN | latexin | -0.00475062 |
| NSD2 | nuclear receptor binding SET domain protein 2 | -0.0047368 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -0.00473427 |
| GPD1L | glycerol-3-phosphate dehydrogenase 1-like | -0.0047309 |
| HRASLS | HRAS-like suppressor | -0.00473029 |
| MANSC1 | MANSC domain containing 1 | -0.00472948 |
| CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 | -0.00472743 |
| CADM1 | cell adhesion molecule 1 | -0.00472318 |
| NAA40 | N(alpha)-acetyltransferase 40, NatD catalytic subunit | -0.00472105 |
| ADAT1 | adenosine deaminase, tRNA-specific 1 | -0.00470967 |
| FEN1 | flap structure-specific endonuclease 1 | -0.0047037 |
| SIDT1 | SID1 transmembrane family, member 1 | -0.00469988 |
| CACNA2D2 | calcium channel, voltage-dependent, alpha 2/delta subunit 2 | -0.00469708 |
| NPY | neuropeptide Y | -0.00468979 |
| NRXN3 | neurexin 3 | -0.00468289 |
| SEZ6L2 | seizure related 6 homolog (mouse)-like 2 | -0.00468044 |
| LTF | lactotransferrin | -0.0046631 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) | -0.00466201 |
| TROAP | trophinin associated protein | -0.00465958 |
| CYP51A1 | cytochrome P450, family 51, subfamily A, polypeptide 1 | -0.00465733 |
| FLNA | filamin A, alpha | -0.00464893 |
| RAB21 | RAB21, member RAS oncogene family | -0.00464659 |
| BCAT2 | branched chain amino-acid transaminase 2, mitochondrial | -0.00464344 |
| PCSK1 | proprotein convertase subtilisin/kexin type 1 | -0.00464067 |
| TMEM254 | transmembrane protein 254 | -0.00463662 |
| SLC2A4RG | SLC2A4 regulator | -0.00463295 |
| ISYNA1 | inositol-3-phosphate synthase 1 | -0.00463096 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.00462825 |
| CYP2B6 | cytochrome P450, family 2, subfamily B, polypeptide 6 | -0.00460262 |
| TNFSF13B | tumor necrosis factor (ligand) superfamily, member 13b | -0.00460013 |
| ABCB6 | ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) | -0.00459684 |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 | -0.00459644 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.00459571 |
| RNF43 | ring finger protein 43 | -0.00459544 |
| SLCO4C1 | solute carrier organic anion transporter family, member 4C1 | -0.00459123 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.00457997 |
| GTSE1 | G-2 and S-phase expressed 1 | -0.00457589 |
| KIF18B | kinesin family member 18B | -0.0045709 |
| THBS1 | thrombospondin 1 | -0.00456383 |
| NOTCH2NL | notch 2 N-terminal like | -0.00455356 |
| ESYT1 | extended synaptotagmin-like protein 1 | -0.00454589 |
| SRRM1 | serine/arginine repetitive matrix 1 | -0.00453389 |
| TMBIM4 | transmembrane BAX inhibitor motif containing 4 | -0.00453222 |
| NMU | neuromedin U | -0.00452034 |
| SV2A | synaptic vesicle glycoprotein 2A | -0.00451637 |
| OGDH | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) | -0.00451561 |
| PRC1 | protein regulator of cytokinesis 1 | -0.00450755 |
| CALD1 | caldesmon 1 | -0.00449886 |
| EXPH5 | exophilin 5 | -0.00449579 |
| TSPAN12 | tetraspanin 12 | -0.00449308 |
| ARG2 | arginase 2 | -0.00447589 |
| NUP210 | nucleoporin 210kDa | -0.00446745 |
| HMGB2 | high mobility group box 2 | -0.00446744 |
| MAGEF1 | melanoma antigen family F1 | -0.00446052 |
| AGPAT1 | 1-acylglycerol-3-phosphate O-acyltransferase 1 | -0.00445841 |
| TACC3 | transforming, acidic coiled-coil containing protein 3 | -0.00445412 |
| BTBD2 | BTB (POZ) domain containing 2 | -0.00444719 |
| NUSAP1 | nucleolar and spindle associated protein 1 | -0.0044342 |
| TSPAN7 | tetraspanin 7 | -0.00442762 |
| RASA4 | RAS p21 protein activator 4 | -0.00442141 |
| MINPP1 | multiple inositol-polyphosphate phosphatase 1 | -0.00442038 |
| CLGN | calmegin | -0.00441585 |
| NDRG2 | NDRG family member 2 | -0.00441236 |
| GREB1 | growth regulation by estrogen in breast cancer 1 | -0.00441014 |
| RAI2 | retinoic acid induced 2 | -0.00440052 |
| ATP13A2 | ATPase type 13A2 | -0.00438892 |
| SPCS3 | signal peptidase complex subunit 3 homolog (S. cerevisiae) | -0.00438193 |
