CA14 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description carbonic anhydrase XIV|Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA XIV is predicted to be a type I membrane protein and shares highest sequence similarity with the other transmembrane CA isoform, CA XII; however, they have different patterns of tissue-specific expression and thus may play different physiologic roles. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 23632)
External Link https://ncbi.nlm.nih.gov/gene/23632
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Genes

500 genes differentially expressed following the CA14 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
BMP4 bone morphogenetic protein 4 0.0165119
ADO 2-aminoethanethiol (cysteamine) dioxygenase 0.0140284
IGFBP6 insulin-like growth factor binding protein 6 0.00969252
XPO7 exportin 7 0.00952647
GULP1 GULP, engulfment adaptor PTB domain containing 1 0.00904427
S100P S100 calcium binding protein P 0.00885476
ZNF185 zinc finger protein 185 (LIM domain) 0.00878434
LCN2 lipocalin 2 0.00864455
DPYSL2 dihydropyrimidinase-like 2 0.00863447
CALB1 calbindin 1, 28kDa 0.00815131
RHCG Rh family, C glycoprotein 0.0077607
SLC6A14 solute carrier family 6 (amino acid transporter), member 14 0.00775252
IPO13 importin 13 0.00772329
S100A9 S100 calcium binding protein A9 0.00734654
FXYD3 FXYD domain containing ion transport regulator 3 0.00703572
MMP12 matrix metallopeptidase 12 0.007027
TACSTD2 tumor-associated calcium signal transducer 2 0.00685656
SULF1 sulfatase 1 0.00675637
TSPO translocator protein (18kDa) 0.00672662
CAPG capping protein (actin filament), gelsolin-like 0.00670903
PLBD1 phospholipase B domain containing 1 0.00665271
DRAM1 DNA-damage regulated autophagy modulator 1 0.00663646
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 0.00659016
FKBP11 FK506 binding protein 11, 19 kDa 0.00652905
CD9 CD9 molecule 0.00651002
WASHC4 WASH complex subunit 4 0.00647081
ANXA6 annexin A6 0.00645439
COG7 component of oligomeric golgi complex 7 0.00638771
ACSM3 acyl-CoA synthetase medium-chain family member 3 0.00636104
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 0.00630006
SLPI secretory leukocyte peptidase inhibitor 0.00627122
COL9A2 collagen, type IX, alpha 2 0.00625438
TRAPPC3 trafficking protein particle complex 3 0.00612352
CSTA cystatin A (stefin A) 0.00611815
MAL mal, T-cell differentiation protein 0.0060875
S100A8 S100 calcium binding protein A8 0.00605644
TNNT1 troponin T type 1 (skeletal, slow) 0.0060303
PKM pyruvate kinase, muscle 0.00600041
DHCR24 24-dehydrocholesterol reductase 0.00594665
SIRPA signal-regulatory protein alpha 0.00593163
LEFTY1 left-right determination factor 1 0.00589995
GPRC5A G protein-coupled receptor, class C, group 5, member A 0.0058855
MYB v-myb avian myeloblastosis viral oncogene homolog 0.00585268
KDM5D lysine (K)-specific demethylase 5D 0.00583982
S100A14 S100 calcium binding protein A14 0.00583883
EAF2 ELL associated factor 2 0.00576675
DACH1 dachshund family transcription factor 1 0.00573815
PFKM phosphofructokinase, muscle 0.00569282
NUDT4 nudix (nucleoside diphosphate linked moiety X)-type motif 4 0.00569244
GSTP1 glutathione S-transferase pi 1 0.00568817
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6 0.00567932
BAMBI BMP and activin membrane-bound inhibitor 0.00564104
MBOAT7 membrane bound O-acyltransferase domain containing 7 0.00561146
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 0.00557199
PDZK1IP1 PDZK1 interacting protein 1 0.00556688
EIF1AY eukaryotic translation initiation factor 1A, Y-linked 0.00555785
NPIPB3 nuclear pore complex interacting protein family, member B3 0.00555199
MAMLD1 mastermind-like domain containing 1 0.00554013
SYNE3 spectrin repeat containing, nuclear envelope family member 3 0.00552553
CDK14 cyclin-dependent kinase 14 0.00552515
LTA4H leukotriene A4 hydrolase 0.00550156
KDELR3 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 0.00549418
MUC5B mucin 5B, oligomeric mucus/gel-forming 0.00548038
SPINT1 serine peptidase inhibitor, Kunitz type 1 0.00545821
STXBP2 syntaxin binding protein 2 0.00545497
PRKCA protein kinase C, alpha 0.00541348
MZB1 marginal zone B and B1 cell-specific protein 0.00540705
ZFP36L2 ZFP36 ring finger protein-like 2 0.00540035
CDH16 cadherin 16, KSP-cadherin 0.00538603
CAPN1 calpain 1, (mu/I) large subunit 0.00538398
FLRT3 fibronectin leucine rich transmembrane protein 3 0.00538112
CRNN cornulin 0.00536569
KLK11 kallikrein-related peptidase 11 0.00531495
NEBL nebulette 0.00530172
MSMB microseminoprotein, beta- 0.00526169
STK38 serine/threonine kinase 38 0.00524222
PTK2B protein tyrosine kinase 2 beta 0.00523196
ENC1 ectodermal-neural cortex 1 (with BTB domain) 0.00521574
AZU1 azurocidin 1 0.00519829
SMYD3 SET and MYND domain containing 3 0.00519473
BAX BCL2-associated X protein 0.00517348
SCPEP1 serine carboxypeptidase 1 0.00516962
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.00515944
CEMIP cell migration inducing protein, hyaluronan binding 0.00514506
SUGCT succinyl-CoA:glutarate-CoA transferase 0.00513126
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 0.00512105
CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein) 0.00510542
TFF1 trefoil factor 1 0.00508671
CRYM crystallin, mu 0.00507189
FERMT1 fermitin family member 1 0.00506226
ALDH3B1 aldehyde dehydrogenase 3 family, member B1 0.0050522
RBPJ recombination signal binding protein for immunoglobulin kappa J region 0.00503966
GLUL glutamate-ammonia ligase 0.00503595
GUCY2C guanylate cyclase 2C 0.00503554
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14 0.00500644
PENK proenkephalin 0.0049719
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3 0.00496486
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2 0.00493262
TLE4 transducin-like enhancer of split 4 0.0049281
SPRR3 small proline-rich protein 3 0.00492055
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 0.0049153
PLK1 polo-like kinase 1 0.00490799
MMP1 matrix metallopeptidase 1 0.00489375
DPEP1 dipeptidase 1 (renal) 0.00488685
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1 0.00487938
KRT13 keratin 13, type I 0.00487723
PDAP1 PDGFA associated protein 1 0.00485612
KLK10 kallikrein-related peptidase 10 0.00484987
INHBA inhibin, beta A 0.0048436
ARPP19 cAMP-regulated phosphoprotein, 19kDa 0.00483704
GPX1 glutathione peroxidase 1 0.00483234
UMOD uromodulin 0.00481793
NCF2 neutrophil cytosolic factor 2 0.00481433
DDAH2 dimethylarginine dimethylaminohydrolase 2 0.00480265
BTF3P11 basic transcription factor 3 pseudogene 11 0.00480167
PNMA2 paraneoplastic Ma antigen 2 0.00480135
GATA6 GATA binding protein 6 0.00480101
TST thiosulfate sulfurtransferase (rhodanese) 0.00479495
PHLDA1 pleckstrin homology-like domain, family A, member 1 0.00479115
COBL cordon-bleu WH2 repeat protein 0.00477746
PGM3 phosphoglucomutase 3 0.00477307
TCAF1 TRPM8 channel-associated factor 1 0.00475486
PYCARD PYD and CARD domain containing 0.00473668
EFHD1 EF-hand domain family, member D1 0.00472569
CETN2 centrin, EF-hand protein, 2 0.00472126
SHB Src homology 2 domain containing adaptor protein B 0.00471624
FOXC1 forkhead box C1 0.00471558
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B 0.00470896
ITFG1 integrin alpha FG-GAP repeat containing 1 0.00470734
MYL6B myosin, light chain 6B, alkali, smooth muscle and non-muscle 0.00469496
TP53I3 tumor protein p53 inducible protein 3 0.00468515
VAMP8 vesicle-associated membrane protein 8 0.00468511
SLC15A2 solute carrier family 15 (oligopeptide transporter), member 2 0.00465681
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10 0.00464097
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) 0.00461804
SCNN1A sodium channel, non voltage gated 1 alpha subunit 0.00459163
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein 0.004584
AKAP9 A kinase (PRKA) anchor protein 9 0.00456777
SH3YL1 SH3 and SYLF domain containing 1 0.004564
SOCS2 suppressor of cytokine signaling 2 0.00453706
KIAA0930 KIAA0930 0.00451585
EHD3 EH-domain containing 3 0.00448583
TNNC1 troponin C type 1 (slow) 0.00448167
MSLN mesothelin 0.00447897
S100A10 S100 calcium binding protein A10 0.00447449
BTK Bruton agammaglobulinemia tyrosine kinase 0.00447327
PAPSS1 3'-phosphoadenosine 5'-phosphosulfate synthase 1 0.00445904
CKAP4 cytoskeleton-associated protein 4 0.00445135
KCNJ15 potassium channel, inwardly rectifying subfamily J, member 15 0.00443412
MUC1 mucin 1, cell surface associated 0.004433
SNX7 sorting nexin 7 0.00442229
MME membrane metallo-endopeptidase 0.00440933
BPGM 2,3-bisphosphoglycerate mutase 0.00440452
PI3 peptidase inhibitor 3, skin-derived 0.00438918
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans) 0.00438398
CRELD2 cysteine-rich with EGF-like domains 2 0.00437414
EGF epidermal growth factor 0.0043659
HAS2 hyaluronan synthase 2 0.0043511
STK39 serine threonine kinase 39 0.00434744
ROGDI rogdi homolog (Drosophila) 0.00434279
LPCAT1 lysophosphatidylcholine acyltransferase 1 0.00433106
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase 0.00432705
RANBP9 RAN binding protein 9 0.00432587
ATP6V1F ATPase, H+ transporting, lysosomal 14kDa, V1 subunit F 0.00432128
EPB41L1 erythrocyte membrane protein band 4.1-like 1 0.00431728
ERBB4 erb-b2 receptor tyrosine kinase 4 0.00429805
KLK13 kallikrein-related peptidase 13 0.00428999
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme 0.00428514
LTBP1 latent transforming growth factor beta binding protein 1 0.0042779
RNASE3 ribonuclease, RNase A family, 3 0.00427582
CRABP2 cellular retinoic acid binding protein 2 0.00425815
FHOD3 formin homology 2 domain containing 3 0.00425761
VNN1 vanin 1 0.00424753
SMAD6 SMAD family member 6 0.00423456
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) 0.00422287
RPS4Y1 ribosomal protein S4, Y-linked 1 0.00419383
FGFR3 fibroblast growth factor receptor 3 0.00419128
CXCL3 chemokine (C-X-C motif) ligand 3 0.00417147
ACOT7 acyl-CoA thioesterase 7 0.00417102
BST1 bone marrow stromal cell antigen 1 0.00415222
ARHGEF18 Rho/Rac guanine nucleotide exchange factor (GEF) 18 0.00413169
AOC1 amine oxidase, copper containing 1 0.00413037
VCAN versican 0.00412446
KLK12 kallikrein-related peptidase 12 0.00412123
EPHB4 EPH receptor B4 0.00411706
AMOTL2 angiomotin like 2 0.00411012
LAMTOR5 late endosomal/lysosomal adaptor, MAPK and MTOR activator 5 0.0041084
DNAJC7 DnaJ (Hsp40) homolog, subfamily C, member 7 0.00410245
RBM34 RNA binding motif protein 34 0.00410016
OPTN optineurin 0.00409075
MYO5C myosin VC 0.00407605
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated) 0.00407293
CLIC3 chloride intracellular channel 3 0.00406743
FXYD2 FXYD domain containing ion transport regulator 2 0.00405574
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9 0.00405232
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5 0.00405137
SMAGP small cell adhesion glycoprotein 0.00402376
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1 0.00401531
PCTP phosphatidylcholine transfer protein 0.0040064
COL11A1 collagen, type XI, alpha 1 0.00399139
CTBS chitobiase, di-N-acetyl- 0.00398451
EHF ets homologous factor 0.00396927
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8 0.00394999
RHBDF1 rhomboid 5 homolog 1 (Drosophila) 0.00394591
COPS7A COP9 signalosome subunit 7A 0.00394478
S100A7 S100 calcium binding protein A7 0.00392611
CRYBG1 crystallin beta-gamma domain containing 1 0.00392162
PRKCZ protein kinase C, zeta 0.00392148
EPS8L2 EPS8-like 2 0.00391942
ARHGEF10 Rho guanine nucleotide exchange factor (GEF) 10 0.00391685
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12 0.00391319
SLC14A1 solute carrier family 14 (urea transporter), member 1 (Kidd blood group) 0.00391223
LRRC8D leucine rich repeat containing 8 family, member D 0.00391126
CREB3L2 cAMP responsive element binding protein 3-like 2 0.00390863
ZFYVE9 zinc finger, FYVE domain containing 9 0.00390268
SOSTDC1 sclerostin domain containing 1 0.00389828
CA2 carbonic anhydrase II 0.00388899
SLC12A1 solute carrier family 12 (sodium/potassium/chloride transporter), member 1 0.00388483
LPIN1 lipin 1 0.00388114
ALDH3A2 aldehyde dehydrogenase 3 family, member A2 0.00387689
LRBA LPS-responsive vesicle trafficking, beach and anchor containing 0.00387587
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1 0.00387384
FOLR1 folate receptor 1 (adult) 0.00387135
PPP1R3C protein phosphatase 1, regulatory subunit 3C 0.00386605
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5 0.00386503
DACT1 dishevelled-binding antagonist of beta-catenin 1 0.00386388
ANXA11 annexin A11 0.00386124
PDE4DIP phosphodiesterase 4D interacting protein 0.00386078
OSBPL1A oxysterol binding protein-like 1A 0.00385279
NBEAL2 neurobeachin-like 2 0.00384937
LTF lactotransferrin 0.0038437
ZBED2 zinc finger, BED-type containing 2 0.00384142
STX3 syntaxin 3 0.00383949
CAPN3 calpain 3, (p94) 0.00383698
TMPRSS11D transmembrane protease, serine 11D 0.00383231
RNF167 ring finger protein 167 0.00381967
AP1S1 adaptor-related protein complex 1, sigma 1 subunit 0.00381788
COBLL1 cordon-bleu WH2 repeat protein-like 1 0.00381351
FLNA filamin A, alpha 0.00381335
CRISP3 cysteine-rich secretory protein 3 0.00381282
IL1RN interleukin 1 receptor antagonist 0.00381156
HK3 hexokinase 3 (white cell) 0.00380708
ITGB7 integrin, beta 7 0.00380694
COQ8A coenzyme Q8A 0.00380194
DDN dendrin 0.00379941
AHCYL2 adenosylhomocysteinase-like 2 0.00379594
PGD phosphogluconate dehydrogenase 0.00379498
IVNS1ABP influenza virus NS1A binding protein 0.00377831
ANXA3 annexin A3 0.00377268
COL9A3 collagen, type IX, alpha 3 0.00377199

decreased expression

Symbol Name Standardized Value
SPARCL1 SPARC-like 1 (hevin) -0.0127463
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -0.0110241
LYZ lysozyme -0.0100511
RGS5 regulator of G-protein signaling 5 -0.00971441
ITM2A integral membrane protein 2A -0.00964921
LGALS13 lectin, galactoside-binding, soluble, 13 -0.00925503
HSPB1 heat shock 27kDa protein 1 -0.00914612
A2M alpha-2-macroglobulin -0.0090262
SSBP2 single-stranded DNA binding protein 2 -0.00899767
TGFBI transforming growth factor, beta-induced, 68kDa -0.00897419
APOLD1 apolipoprotein L domain containing 1 -0.0089145
CLEC2B C-type lectin domain family 2, member B -0.00876577
FCGBP Fc fragment of IgG binding protein -0.00864503
UCP2 uncoupling protein 2 (mitochondrial, proton carrier) -0.00854138
VWF von Willebrand factor -0.00853076
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase) -0.00830047
COL15A1 collagen, type XV, alpha 1 -0.00796603
PLIN2 perilipin 2 -0.00777953
CD36 CD36 molecule (thrombospondin receptor) -0.00774518
GIMAP6 GTPase, IMAP family member 6 -0.00767697
GPR183 G protein-coupled receptor 183 -0.00763423
FABP4 fatty acid binding protein 4, adipocyte -0.00754574
CXCL14 chemokine (C-X-C motif) ligand 14 -0.00753163
C1QA complement component 1, q subcomponent, A chain -0.00740633
RBM3 RNA binding motif (RNP1, RRM) protein 3 -0.00740518
COL6A2 collagen, type VI, alpha 2 -0.00736183
CCL19 chemokine (C-C motif) ligand 19 -0.00732406
CD163 CD163 molecule -0.00726717
RNASE1 ribonuclease, RNase A family, 1 (pancreatic) -0.00726634
PDLIM3 PDZ and LIM domain 3 -0.00726427
GIMAP5 GTPase, IMAP family member 5 -0.00719117
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1 -0.00717114
ACKR1 atypical chemokine receptor 1 (Duffy blood group) -0.00714017
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha -0.00711689
RGS1 regulator of G-protein signaling 1 -0.00711603
CHN2 chimerin 2 -0.00701443
PLXDC1 plexin domain containing 1 -0.00699592
SEPP1 selenoprotein P, plasma, 1 -0.00695383
CCNB1 cyclin B1 -0.00694212
RTN1 reticulon 1 -0.00692803
ADIPOQ adiponectin, C1Q and collagen domain containing -0.00686448
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon -0.00684111
PLVAP plasmalemma vesicle associated protein -0.00673068
NRN1 neuritin 1 -0.00671414
SCD5 stearoyl-CoA desaturase 5 -0.00669526
CD93 CD93 molecule -0.0066932
CDH5 cadherin 5, type 2 (vascular endothelium) -0.00665945
ADAT1 adenosine deaminase, tRNA-specific 1 -0.00664068
MCAM melanoma cell adhesion molecule -0.00663238
MAN2A1 mannosidase, alpha, class 2A, member 1 -0.00661634
REEP1 receptor accessory protein 1 -0.00657959
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila) -0.00654311
ASPH aspartate beta-hydroxylase -0.00651766
CLDN5 claudin 5 -0.00643422
GNG11 guanine nucleotide binding protein (G protein), gamma 11 -0.00639193
HEY1 hes-related family bHLH transcription factor with YRPW motif 1 -0.00636422
PLIN1 perilipin 1 -0.00635235
SCGB1D2 secretoglobin, family 1D, member 2 -0.00628046
FOXF1 forkhead box F1 -0.00623779
MT1M metallothionein 1M -0.00621042
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -0.00620868
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) -0.00619054
LAMA4 laminin, alpha 4 -0.00617236
EDNRB endothelin receptor type B -0.00606646
PPARG peroxisome proliferator-activated receptor gamma -0.0060185
ENPEP glutamyl aminopeptidase (aminopeptidase A) -0.00599309
PCDH17 protocadherin 17 -0.00598526
EGLN3 egl-9 family hypoxia-inducible factor 3 -0.00598318
HSPB8 heat shock 22kDa protein 8 -0.00597329
ADGRF5 adhesion G protein-coupled receptor F5 -0.0059727
MEN1 multiple endocrine neoplasia I -0.00586822
STXBP6 syntaxin binding protein 6 (amisyn) -0.00578809
RNASE6 ribonuclease, RNase A family, k6 -0.00577531
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) -0.0057482
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit -0.00570701
STAB1 stabilin 1 -0.00568731
CPVL carboxypeptidase, vitellogenic-like -0.00568442
COL6A3 collagen, type VI, alpha 3 -0.00568048
IFI44 interferon-induced protein 44 -0.00567107
INSR insulin receptor -0.00566263
MPPED2 metallophosphoesterase domain containing 2 -0.00561145
DUSP5 dual specificity phosphatase 5 -0.00559021
PTP4A3 protein tyrosine phosphatase type IVA, member 3 -0.00556563
C1QB complement component 1, q subcomponent, B chain -0.00552451
LIMS1 LIM and senescent cell antigen-like domains 1 -0.00549565
LYVE1 lymphatic vessel endothelial hyaluronan receptor 1 -0.00549186
C3 complement component 3 -0.0054689
PPAP2A phosphatidic acid phosphatase type 2A -0.00543905
HLA-B major histocompatibility complex, class I, B -0.00543855
OLFM1 olfactomedin 1 -0.0053755
THBS4 thrombospondin 4 -0.00534818
MTUS1 microtubule associated tumor suppressor 1 -0.00533751
CPM carboxypeptidase M -0.0053278
PXDC1 PX domain containing 1 -0.0053248
ACTG2 actin, gamma 2, smooth muscle, enteric -0.0052772
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1 -0.00525801
C1S complement component 1, s subcomponent -0.00525263
SLCO2B1 solute carrier organic anion transporter family, member 2B1 -0.00522091
CPE carboxypeptidase E -0.00522064
FZD6 frizzled class receptor 6 -0.00519316
F2R coagulation factor II (thrombin) receptor -0.00519315
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 -0.00519223
COL18A1 collagen, type XVIII, alpha 1 -0.00518677
TSC22D1 TSC22 domain family, member 1 -0.00516348
ABHD3 abhydrolase domain containing 3 -0.00516248
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta -0.00515969
ADM adrenomedullin -0.00515605
PIP prolactin-induced protein -0.00508252
GPX3 glutathione peroxidase 3 -0.00505678
NES nestin -0.00502531
EDN3 endothelin 3 -0.00501912
GNG12 guanine nucleotide binding protein (G protein), gamma 12 -0.00499505
FABP5 fatty acid binding protein 5 (psoriasis-associated) -0.00497944
SHOX2 short stature homeobox 2 -0.00496849
GRAMD2B GRAM domain containing 2B -0.00494898
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -0.00490976
PPP1R2 protein phosphatase 1, regulatory (inhibitor) subunit 2 -0.00490703
F2RL1 coagulation factor II (thrombin) receptor-like 1 -0.00490626
SYNM synemin, intermediate filament protein -0.00490579
SCGB2A2 secretoglobin, family 2A, member 2 -0.00489842
SKAP2 src kinase associated phosphoprotein 2 -0.00489505
MAP3K7CL MAP3K7 C-terminal like -0.00489108
CD209 CD209 molecule -0.00487624
PCSK1 proprotein convertase subtilisin/kexin type 1 -0.00483469
ADA adenosine deaminase -0.00482735
ERBIN erbb2 interacting protein -0.00482683
DSC1 desmocollin 1 -0.0047763
FBXO11 F-box protein 11 -0.00477131
CD53 CD53 molecule -0.00476523
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9 -0.00475214
ELOVL5 ELOVL fatty acid elongase 5 -0.0047424
ITPRID2 ITPR interacting domain containing 2 -0.00473926
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) -0.00473442
INPP5A inositol polyphosphate-5-phosphatase, 40kDa -0.00471335
MRPS30 mitochondrial ribosomal protein S30 -0.00470822
BCHE butyrylcholinesterase -0.00470699
CHIC2 cysteine-rich hydrophobic domain 2 -0.00468794
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) -0.00468255
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble) -0.00466453
NNMT nicotinamide N-methyltransferase -0.00464775
TMEM204 transmembrane protein 204 -0.00463211
MCF2L MCF.2 cell line derived transforming sequence-like -0.00462496
CHP2 calcineurin-like EF-hand protein 2 -0.00460826
CXADR coxsackie virus and adenovirus receptor -0.00460509
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 -0.00460294
FABP1 fatty acid binding protein 1, liver -0.00460172
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28 -0.00458572
MSX1 msh homeobox 1 -0.00457612
S1PR1 sphingosine-1-phosphate receptor 1 -0.00457314
NUP85 nucleoporin 85kDa -0.00456647
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide -0.00455715
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) -0.00454922
SLC43A3 solute carrier family 43, member 3 -0.00454572
MYLK myosin light chain kinase -0.00452308
CYTL1 cytokine-like 1 -0.00452182
CPS1 carbamoyl-phosphate synthase 1, mitochondrial -0.00452159
EGR1 early growth response 1 -0.00451449
PLA1A phospholipase A1 member A -0.00451423
SDC3 syndecan 3 -0.00451105
METTL7A methyltransferase like 7A -0.00450721
MYH11 myosin, heavy chain 11, smooth muscle -0.00450155
ADAP2 ArfGAP with dual PH domains 2 -0.00449678
PIP4K2A phosphatidylinositol-5-phosphate 4-kinase, type II, alpha -0.00448549
IGFBP1 insulin-like growth factor binding protein 1 -0.00447167
RUFY3 RUN and FYVE domain containing 3 -0.00445693
PDE3B phosphodiesterase 3B, cGMP-inhibited -0.00444649
DST dystonin -0.00441773
PRELID3B PRELI domain containing 3B -0.00441347
AQP1 aquaporin 1 (Colton blood group) -0.00440024
SCGN secretagogin, EF-hand calcium binding protein -0.0043927
TYROBP TYRO protein tyrosine kinase binding protein -0.00438028
LPAR6 lysophosphatidic acid receptor 6 -0.00437811
SPON1 spondin 1, extracellular matrix protein -0.0043704
MGP matrix Gla protein -0.00436895
RASIP1 Ras interacting protein 1 -0.00434417
GABRE gamma-aminobutyric acid (GABA) A receptor, epsilon -0.00433373
IER2 immediate early response 2 -0.00433008
CRY1 cryptochrome circadian clock 1 -0.00432601
PCSK5 proprotein convertase subtilisin/kexin type 5 -0.00432506
GCLC glutamate-cysteine ligase, catalytic subunit -0.00431771
TAC1 tachykinin, precursor 1 -0.00431654
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) -0.00431389
ADGRG2 adhesion G protein-coupled receptor G2 -0.00430279
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8 -0.00429438
TRAT1 T cell receptor associated transmembrane adaptor 1 -0.00428038
MTTP microsomal triglyceride transfer protein -0.00427034
APOB apolipoprotein B -0.00427028
SASH1 SAM and SH3 domain containing 1 -0.00426927
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 -0.00426713
DCLK1 doublecortin-like kinase 1 -0.00426554
FYB1 FYN binding protein 1 -0.00425744
CHST1 carbohydrate (keratan sulfate Gal-6) sulfotransferase 1 -0.00425578
C3AR1 complement component 3a receptor 1 -0.00425185
FOSB FBJ murine osteosarcoma viral oncogene homolog B -0.00424889
LMO3 LIM domain only 3 (rhombotin-like 2) -0.00423655
STK10 serine/threonine kinase 10 -0.00423594
PAQR3 progestin and adipoQ receptor family member III -0.00422747
ARHGAP29 Rho GTPase activating protein 29 -0.00422656
SLC20A1 solute carrier family 20 (phosphate transporter), member 1 -0.00422034
CHN1 chimerin 1 -0.00421455
RAMP3 receptor (G protein-coupled) activity modifying protein 3 -0.00421363
HOMER1 homer scaffolding protein 1 -0.00420786
S100B S100 calcium binding protein B -0.00420214
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase -0.00419866
RRAGA Ras-related GTP binding A -0.00419847
ANXA1 annexin A1 -0.00419011
COL3A1 collagen, type III, alpha 1 -0.00417787
CSF1R colony stimulating factor 1 receptor -0.0041674
SELENOW selenoprotein W -0.00415863
PMP22 peripheral myelin protein 22 -0.00415709
OPHN1 oligophrenin 1 -0.00415534
TRIM9 tripartite motif containing 9 -0.00415042
TXNDC9 thioredoxin domain containing 9 -0.00414436
CLIC2 chloride intracellular channel 2 -0.00414426
CLDN4 claudin 4 -0.00412408
ERAP1 endoplasmic reticulum aminopeptidase 1 -0.00410449
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 -0.00410411
OSTM1 osteopetrosis associated transmembrane protein 1 -0.0041033
SYNGR2 synaptogyrin 2 -0.00410181
ITK IL2-inducible T-cell kinase -0.00409926
KCNK3 potassium channel, two pore domain subfamily K, member 3 -0.0040881
LY96 lymphocyte antigen 96 -0.00408284
LHFP lipoma HMGIC fusion partner -0.00407778
TCF7 transcription factor 7 (T-cell specific, HMG-box) -0.00407709
CIDEC cell death-inducing DFFA-like effector c -0.00406938
ARAP2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 -0.00405144
CNN1 calponin 1, basic, smooth muscle -0.00404903
SPAG16 sperm associated antigen 16 -0.00402549
KRT20 keratin 20, type I -0.00402536
LDLRAD4 low density lipoprotein receptor class A domain containing 4 -0.00401804
PAX6 paired box 6 -0.00400234
APLNR apelin receptor -0.00400232
LIPG lipase, endothelial -0.00399848
MCCC2 methylcrotonoyl-CoA carboxylase 2 (beta) -0.00399224
BTBD3 BTB (POZ) domain containing 3 -0.00398853
CREM cAMP responsive element modulator -0.00398724
CAV1 caveolin 1, caveolae protein, 22kDa -0.00398709
P2RY14 purinergic receptor P2Y, G-protein coupled, 14 -0.00398473
CP ceruloplasmin (ferroxidase) -0.00398436
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta -0.00398116
SIGLEC1 sialic acid binding Ig-like lectin 1, sialoadhesin -0.00397134
GIMAP4 GTPase, IMAP family member 4 -0.00396606
RGCC regulator of cell cycle -0.00396381
SPRY4 sprouty homolog 4 (Drosophila) -0.00396205
BUD23 BUD23 rRNA methyltransferase and ribosome maturation factor -0.00396063
MMP19 matrix metallopeptidase 19 -0.00395837
CLCA1 chloride channel accessory 1 -0.00394955
RGS16 regulator of G-protein signaling 16 -0.00394525
SRGN serglycin -0.00394396
NPM3 nucleophosmin/nucleoplasmin 3 -0.00394304