| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | carbonic anhydrase IV|Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. This gene encodes a glycosylphosphatidyl-inositol-anchored membrane isozyme expressed on the luminal surfaces of pulmonary (and certain other) capillaries and proximal renal tubules. Its exact function is not known; however, it may have a role in inherited renal abnormalities of bicarbonate transport. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 762) |
| External Link | https://ncbi.nlm.nih.gov/gene/762 |
| Similar Terms | |
| Downloads & Tools |
496 genes differentially expressed following the CA4 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FGFR3 | fibroblast growth factor receptor 3 | 0.0181448 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | 0.0132927 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.0131952 |
| HBB | hemoglobin, beta | 0.0130546 |
| CRIP2 | cysteine-rich protein 2 | 0.0125991 |
| KDM5D | lysine (K)-specific demethylase 5D | 0.0125654 |
| SORD | sorbitol dehydrogenase | 0.0124005 |
| ADO | 2-aminoethanethiol (cysteamine) dioxygenase | 0.012007 |
| PRKCB | protein kinase C, beta | 0.0117324 |
| DCXR | dicarbonyl/L-xylulose reductase | 0.0116806 |
| ZBTB18 | zinc finger and BTB domain containing 18 | 0.0115017 |
| NUSAP1 | nucleolar and spindle associated protein 1 | 0.0113964 |
| CST3 | cystatin C | 0.0109708 |
| DEGS1 | delta(4)-desaturase, sphingolipid 1 | 0.0108489 |
| SLC37A4 | solute carrier family 37 (glucose-6-phosphate transporter), member 4 | 0.0107178 |
| HADHA | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit | 0.0106944 |
| CPVL | carboxypeptidase, vitellogenic-like | 0.0106323 |
| TSPAN8 | tetraspanin 8 | 0.0106303 |
| AKR7A2 | aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) | 0.0106087 |
| TMSB15A | thymosin beta 15a | 0.0105253 |
| ACP3 | acid phosphatase 3 | 0.0104414 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | 0.0103829 |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha | 0.0102872 |
| RAPSN | receptor-associated protein of the synapse | 0.010036 |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit | 0.00998699 |
| CCNF | cyclin F | 0.00985355 |
| GANAB | glucosidase, alpha; neutral AB | 0.00984378 |
| NMU | neuromedin U | 0.00969008 |
| PIN1 | peptidylprolyl cis/trans isomerase, NIMA-interacting 1 | 0.00958674 |
| CHKB | choline kinase beta | 0.00957828 |
| FKBP1B | FK506 binding protein 1B, 12.6 kDa | 0.00942556 |
| OLFM4 | olfactomedin 4 | 0.00942165 |
| C12ORF29 | chromosome 12 open reading frame 29 | 0.00941903 |
| AKAP7 | A kinase (PRKA) anchor protein 7 | 0.00938779 |
| FASN | fatty acid synthase | 0.00935262 |
| IMPA2 | inositol(myo)-1(or 4)-monophosphatase 2 | 0.00928944 |
| SLC44A4 | solute carrier family 44, member 4 | 0.00928578 |
| LEPR | leptin receptor | 0.00923125 |
| ADIRF | adipogenesis regulatory factor | 0.00922591 |
| PRDX2 | peroxiredoxin 2 | 0.00921728 |
| GPSM2 | G-protein signaling modulator 2 | 0.0091857 |
| MNDA | myeloid cell nuclear differentiation antigen | 0.00914998 |
| BEX1 | brain expressed, X-linked 1 | 0.00909454 |
| STEAP1 | six transmembrane epithelial antigen of the prostate 1 | 0.00903745 |
| DDHD2 | DDHD domain containing 2 | 0.00898987 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.00897333 |
| TPSAB1 | tryptase alpha/beta 1 | 0.00896422 |
| NRGN | neurogranin (protein kinase C substrate, RC3) | 0.0089335 |
| THYN1 | thymocyte nuclear protein 1 | 0.00892261 |
| DHCR24 | 24-dehydrocholesterol reductase | 0.0089031 |
| ZNF184 | zinc finger protein 184 | 0.0088085 |
| FBXO5 | F-box protein 5 | 0.00877227 |
| LANCL1 | LanC lantibiotic synthetase component C-like 1 (bacterial) | 0.00874318 |
| AGR2 | anterior gradient 2 | 0.00873039 |
| TNFSF13B | tumor necrosis factor (ligand) superfamily, member 13b | 0.00869498 |
| B3GNT1 | 0.00860615 | |
| NRN1 | neuritin 1 | 0.00852829 |
| LBR | lamin B receptor | 0.00850663 |
| OIP5 | Opa interacting protein 5 | 0.00850097 |
| IDH2 | isocitrate dehydrogenase 2 (NADP+), mitochondrial | 0.00848556 |
| HSD11B1 | hydroxysteroid (11-beta) dehydrogenase 1 | 0.00845771 |
| TM7SF2 | transmembrane 7 superfamily member 2 | 0.00845463 |
| SLC2A4RG | SLC2A4 regulator | 0.00845381 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.00842718 |
| FADS1 | fatty acid desaturase 1 | 0.00840138 |
| THAP12 | THAP domain containing 12 | 0.00833623 |
| FCER1A | Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide | 0.00832424 |
| CD2 | CD2 molecule | 0.0082829 |
| ID4 | inhibitor of DNA binding 4, dominant negative helix-loop-helix protein | 0.00827286 |
| LSM2 | LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae) | 0.00824431 |
| DACH1 | dachshund family transcription factor 1 | 0.00822985 |
| KLHL23 | kelch-like family member 23 | 0.00819851 |
| GCA | grancalcin, EF-hand calcium binding protein | 0.00816715 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.00816509 |
| TMEM106B | transmembrane protein 106B | 0.00808423 |
| PRIM1 | primase, DNA, polypeptide 1 (49kDa) | 0.00805636 |
| HMGB3 | high mobility group box 3 | 0.00803991 |
| CBR3 | carbonyl reductase 3 | 0.00803261 |
| CDKN2C | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) | 0.00802788 |
| RAD51AP1 | RAD51 associated protein 1 | 0.00802341 |
| DBF4 | DBF4 zinc finger | 0.00801104 |
| CDC7 | cell division cycle 7 | 0.00799352 |
| PSRC1 | proline/serine-rich coiled-coil 1 | 0.00796862 |
| CCNB2 | cyclin B2 | 0.00796167 |
| SPC25 | SPC25, NDC80 kinetochore complex component | 0.00795698 |
| PRF1 | perforin 1 (pore forming protein) | 0.007926 |
| ASRGL1 | asparaginase like 1 | 0.00792216 |
| PPA2 | pyrophosphatase (inorganic) 2 | 0.00788576 |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit | 0.007869 |
| DMAC2L | distal membrane arm assembly component 2 like | 0.00785422 |
| RMI1 | RecQ mediated genome instability 1 | 0.00772321 |
| HMGB1 | high mobility group box 1 | 0.00769447 |
| ACAT2 | acetyl-CoA acetyltransferase 2 | 0.00768292 |
| ITGB3BP | integrin beta 3 binding protein (beta3-endonexin) | 0.00767986 |
| NUDT11 | nudix (nucleoside diphosphate linked moiety X)-type motif 11 | 0.00767843 |
| SDHAF3 | succinate dehydrogenase complex assembly factor 3 | 0.00766417 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | 0.00762853 |
| HMGN5 | high mobility group nucleosome binding domain 5 | 0.00760393 |
| MYCN | v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog | 0.0076035 |
| GRAMD1C | GRAM domain containing 1C | 0.00758215 |
| SIRT3 | sirtuin 3 | 0.00754985 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | 0.00753235 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | 0.00751797 |
| ELOVL6 | ELOVL fatty acid elongase 6 | 0.00751511 |
| MDM1 | Mdm1 nuclear protein homolog (mouse) | 0.0075101 |
| YEATS4 | YEATS domain containing 4 | 0.00740792 |
| CD9 | CD9 molecule | 0.00740214 |
| LYZ | lysozyme | 0.00739464 |
| RPA3 | replication protein A3, 14kDa | 0.00739263 |
| LTBP2 | latent transforming growth factor beta binding protein 2 | 0.0073906 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.00738646 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) | 0.00737167 |
| ST6GAL1 | ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 | 0.00736405 |
| CENPU | centromere protein U | 0.00736347 |
| KCND3 | potassium channel, voltage gated Shal related subfamily D, member 3 | 0.00735365 |
| RAB20 | RAB20, member RAS oncogene family | 0.00734861 |
| ENC1 | ectodermal-neural cortex 1 (with BTB domain) | 0.0073305 |
| PIMREG | PICALM interacting mitotic regulator | 0.00732908 |
| TARP | TCR gamma alternate reading frame protein | 0.00731242 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.00731039 |
| NEK2 | NIMA-related kinase 2 | 0.00730175 |
| ECI2 | enoyl-CoA delta isomerase 2 | 0.00727961 |
| HS3ST1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 1 | 0.0072459 |
| METRN | meteorin, glial cell differentiation regulator | 0.00721757 |
| RNASE2 | ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) | 0.00721504 |
| C7 | complement component 7 | 0.00721223 |
| KIF15 | kinesin family member 15 | 0.00719172 |
| NPAT | nuclear protein, ataxia-telangiectasia locus | 0.00717379 |
| KRAS | Kirsten rat sarcoma viral oncogene homolog | 0.00717187 |
| ARG1 | arginase 1 | 0.00715773 |
| CTSK | cathepsin K | 0.00712987 |
| TRMT5 | tRNA methyltransferase 5 | 0.00712275 |
| SPTSSA | serine palmitoyltransferase, small subunit A | 0.00711791 |
| NFIB | nuclear factor I/B | 0.00710976 |
| GLUL | glutamate-ammonia ligase | 0.00710707 |
| GINS1 | GINS complex subunit 1 (Psf1 homolog) | 0.00709466 |
| MCM6 | minichromosome maintenance complex component 6 | 0.00708354 |
| OLFM1 | olfactomedin 1 | 0.00708042 |
| ASF1A | anti-silencing function 1A histone chaperone | 0.00703489 |
| AKR7A3 | aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) | 0.00698265 |
| EIF4E | eukaryotic translation initiation factor 4E | 0.0069785 |
| DDOST | dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic) | 0.00697673 |
| PTCH1 | patched 1 | 0.00697535 |
| RNASEH2A | ribonuclease H2, subunit A | 0.00696114 |
| FBXO3 | F-box protein 3 | 0.00695669 |
| EFCAB11 | EF-hand calcium binding domain 11 | 0.00694288 |
| H1-10 | H1.10 linker histone | 0.00693456 |
| MFHAS1 | malignant fibrous histiocytoma amplified sequence 1 | 0.0069063 |
| CLGN | calmegin | 0.00689874 |
| CCND2 | cyclin D2 | 0.00688949 |
| NQO2 | NAD(P)H dehydrogenase, quinone 2 | 0.00687894 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | 0.00687669 |
| TSPAN6 | tetraspanin 6 | 0.00686688 |
| KIF20A | kinesin family member 20A | 0.00685995 |
| FANCL | Fanconi anemia, complementation group L | 0.00685839 |
| MSMB | microseminoprotein, beta- | 0.00683986 |
| GGH | gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) | 0.00683173 |
| HELLS | helicase, lymphoid-specific | 0.00681848 |
| GNAL | guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type | 0.00680017 |
| BIRC5 | baculoviral IAP repeat containing 5 | 0.00679269 |
| CKAP2 | cytoskeleton associated protein 2 | 0.00678497 |
| HOXC6 | homeobox C6 | 0.00676287 |
| GLO1 | glyoxalase I | 0.00671259 |
| GET1 | guided entry of tail-anchored proteins factor 1 | 0.00670962 |
| MYB | v-myb avian myeloblastosis viral oncogene homolog | 0.00670904 |
| ZNF443 | zinc finger protein 443 | 0.00669568 |
| RTN1 | reticulon 1 | 0.00668303 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.00666729 |
| AURKA | aurora kinase A | 0.00666156 |
| UBR7 | ubiquitin protein ligase E3 component n-recognin 7 (putative) | 0.00666032 |
| FLOT2 | flotillin 2 | 0.00664818 |
| ALDH3A2 | aldehyde dehydrogenase 3 family, member A2 | 0.0066257 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | 0.0066011 |
| CYP39A1 | cytochrome P450, family 39, subfamily A, polypeptide 1 | 0.00659675 |
| SLC27A2 | solute carrier family 27 (fatty acid transporter), member 2 | 0.00659195 |
| MSMO1 | methylsterol monooxygenase 1 | 0.00658875 |
| CRLF1 | cytokine receptor-like factor 1 | 0.00656615 |
| PER3 | period circadian clock 3 | 0.00655693 |
| PCP4 | Purkinje cell protein 4 | 0.00654823 |
| YPEL1 | yippee-like 1 (Drosophila) | 0.00653765 |
| CSTF2T | cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant | 0.00651281 |
| ERI2 | ERI1 exoribonuclease family member 2 | 0.00650142 |
| FZD5 | frizzled class receptor 5 | 0.00650102 |
| MANSC1 | MANSC domain containing 1 | 0.00649843 |
| SERINC5 | serine incorporator 5 | 0.00649656 |
| OGFOD3 | 2-oxoglutarate and iron-dependent oxygenase domain containing 3 | 0.00647395 |
| DFFB | DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) | 0.00646592 |
| DUT | deoxyuridine triphosphatase | 0.00646166 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | 0.00644901 |
| AMACR | alpha-methylacyl-CoA racemase | 0.00644784 |
| CD320 | CD320 molecule | 0.00644534 |
| RXRA | retinoid X receptor, alpha | 0.00644519 |
| KYAT3 | kynurenine aminotransferase 3 | 0.00642923 |
| SYBU | syntabulin (syntaxin-interacting) | 0.0064291 |
| KIF18B | kinesin family member 18B | 0.00641031 |
| CSRP3 | cysteine and glycine-rich protein 3 (cardiac LIM protein) | 0.00640683 |
| SEPHS1 | selenophosphate synthetase 1 | 0.0064053 |
| LIG1 | ligase I, DNA, ATP-dependent | 0.00638788 |
| APIP | APAF1 interacting protein | 0.00638567 |
| RDH11 | retinol dehydrogenase 11 (all-trans/9-cis/11-cis) | 0.00637475 |
| PHB2 | prohibitin 2 | 0.00637439 |
| LIPT1 | lipoyltransferase 1 | 0.00635595 |
| ICMT | isoprenylcysteine carboxyl methyltransferase | 0.00632906 |
| PGAP1 | post-GPI attachment to proteins 1 | 0.00632824 |
| BCL11B | B-cell CLL/lymphoma 11B (zinc finger protein) | 0.00630713 |
| NEIL3 | nei endonuclease VIII-like 3 (E. coli) | 0.00630267 |
| SELENOW | selenoprotein W | 0.00629231 |
| ENPP4 | ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative) | 0.00628396 |
| SLC19A1 | solute carrier family 19 (folate transporter), member 1 | 0.00627787 |
| RXYLT1 | ribitol xylosyltransferase 1 | 0.00627332 |
| PLN | phospholamban | 0.0062663 |
| NPTX2 | neuronal pentraxin II | 0.00626343 |
| INSIG1 | insulin induced gene 1 | 0.00626158 |
| CBR4 | carbonyl reductase 4 | 0.00626068 |
| ASH2L | ash2 (absent, small, or homeotic)-like (Drosophila) | 0.00625815 |
| SFTPC | surfactant protein C | 0.00625281 |
| ARL3 | ADP-ribosylation factor-like 3 | 0.00624653 |
| TCFL5 | transcription factor-like 5 (basic helix-loop-helix) | 0.00624336 |
| RNFT2 | ring finger protein, transmembrane 2 | 0.00624314 |
| NCAPD3 | non-SMC condensin II complex, subunit D3 | 0.00623776 |
| LDAH | lipid droplet associated hydrolase | 0.00623169 |
| CCL5 | chemokine (C-C motif) ligand 5 | 0.00622969 |
| APMAP | adipocyte plasma membrane associated protein | 0.00622544 |
| GATM | glycine amidinotransferase (L-arginine:glycine amidinotransferase) | 0.00622544 |
| C3ORF14 | chromosome 3 open reading frame 14 | 0.00620111 |
| RAB25 | RAB25, member RAS oncogene family | 0.00619973 |
| SORBS1 | sorbin and SH3 domain containing 1 | 0.00619798 |
| ANGEL2 | angel homolog 2 (Drosophila) | 0.00618234 |
| DCAF11 | DDB1 and CUL4 associated factor 11 | 0.00617482 |
| NAAA | N-acylethanolamine acid amidase | 0.00617452 |
| PSPH | phosphoserine phosphatase | 0.00616737 |
| WNT5A | wingless-type MMTV integration site family, member 5A | 0.00616688 |
| PSIP1 | PC4 and SFRS1 interacting protein 1 | 0.00613904 |
| ALDH2 | aldehyde dehydrogenase 2 family (mitochondrial) | 0.0061385 |
| TOR3A | torsin family 3, member A | 0.00613779 |
| COCH | cochlin | 0.00613604 |
| ZCCHC10 | zinc finger, CCHC domain containing 10 | 0.00613481 |
| PCCB | propionyl CoA carboxylase, beta polypeptide | 0.00611799 |
| IL27RA | interleukin 27 receptor, alpha | 0.00611772 |
| NPY | neuropeptide Y | 0.00609903 |
| NUP85 | nucleoporin 85kDa | 0.00608816 |
| FGL2 | fibrinogen-like 2 | 0.00608173 |
| FBP1 | fructose-1,6-bisphosphatase 1 | 0.00607705 |
| ACTL6A | actin-like 6A | 0.00607163 |
| CCNA2 | cyclin A2 | 0.00606312 |
| AMD1 | adenosylmethionine decarboxylase 1 | 0.00605284 |
| NTS | neurotensin | 0.00605151 |
| SPAG4 | sperm associated antigen 4 | 0.00604912 |
| HPF1 | histone PARylation factor 1 | 0.00604818 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA1A | heat shock 70kDa protein 1A | -0.0223651 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | -0.0199287 |
| HSPB1 | heat shock 27kDa protein 1 | -0.019888 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0196807 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.0190722 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0190384 |
| CRYAB | crystallin, alpha B | -0.0188016 |
| MX1 | MX dynamin-like GTPase 1 | -0.0175251 |
| KRT14 | keratin 14, type I | -0.0170388 |
| ATF3 | activating transcription factor 3 | -0.0161161 |
| XIC | X chromosome inactivation center | -0.0158044 |
| RFTN1 | raftlin, lipid raft linker 1 | -0.0157444 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | -0.015071 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0150035 |
| POSTN | periostin, osteoblast specific factor | -0.0145966 |
| GABRP | gamma-aminobutyric acid (GABA) A receptor, pi | -0.0144267 |
| IFI44L | interferon-induced protein 44-like | -0.0144189 |
| IER5 | immediate early response 5 | -0.0143926 |
| PLK2 | polo-like kinase 2 | -0.0138084 |
| C3 | complement component 3 | -0.0137137 |
| RND3 | Rho family GTPase 3 | -0.0136717 |
| KRT23 | keratin 23, type I | -0.0134046 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | -0.0133779 |
| ADM | adrenomedullin | -0.0133274 |
| ECM1 | extracellular matrix protein 1 | -0.0132753 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0132279 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | -0.0131338 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0131031 |
| IFI44 | interferon-induced protein 44 | -0.0130544 |
| TNNC1 | troponin C type 1 (slow) | -0.0130274 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0129681 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | -0.0126981 |
| ANXA1 | annexin A1 | -0.0124232 |
| SCGB2A1 | secretoglobin, family 2A, member 1 | -0.0123853 |
| OXTR | oxytocin receptor | -0.0123277 |
| KRT7 | keratin 7, type II | -0.0122637 |
| PEG10 | paternally expressed 10 | -0.0121065 |
| HSPB8 | heat shock 22kDa protein 8 | -0.0120809 |
| KLF6 | Kruppel-like factor 6 | -0.0119269 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | -0.0119242 |
| SWAP70 | SWAP switching B-cell complex 70kDa subunit | -0.0118729 |
| CCN2 | cellular communication network factor 2 | -0.0118581 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | -0.01168 |
| MIR22HG | MIR22 host gene | -0.0115676 |
| MVP | major vault protein | -0.0115573 |
| CA12 | carbonic anhydrase XII | -0.0114899 |
| MYOF | myoferlin | -0.0114579 |
| ISG20 | interferon stimulated exonuclease gene 20kDa | -0.0114524 |
| CLEC2B | C-type lectin domain family 2, member B | -0.0113882 |
| FABP4 | fatty acid binding protein 4, adipocyte | -0.0111021 |
| THBS2 | thrombospondin 2 | -0.0110394 |
| SP100 | SP100 nuclear antigen | -0.011016 |
| MMP1 | matrix metallopeptidase 1 | -0.0108515 |
| TCTA | T-cell leukemia translocation altered | -0.0108053 |
| AREG | amphiregulin | -0.0107735 |
| CEL | carboxyl ester lipase | -0.0107488 |
| EGR1 | early growth response 1 | -0.0107371 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0106782 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | -0.0106392 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0104973 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0104864 |
| SGK1 | serum/glucocorticoid regulated kinase 1 | -0.010347 |
| MFAP5 | microfibrillar associated protein 5 | -0.010303 |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') | -0.0103025 |
| HIST1H2BD | histone cluster 1, H2bd | -0.0102779 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0102384 |
| SNAI2 | snail family zinc finger 2 | -0.0102263 |
| KLK10 | kallikrein-related peptidase 10 | -0.0101991 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 | -0.0101968 |
| STC2 | stanniocalcin 2 | -0.0101933 |
| SPRR3 | small proline-rich protein 3 | -0.0101739 |
| MX2 | MX dynamin-like GTPase 2 | -0.0100732 |
| OLFML2A | olfactomedin-like 2A | -0.0100475 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.00990612 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.00986769 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | -0.00981263 |
| FNDC3B | fibronectin type III domain containing 3B | -0.00978334 |
| MGLL | monoglyceride lipase | -0.00976036 |
| GNAS | GNAS complex locus | -0.00975113 |
| DIPK1A | divergent protein kinase domain 1A | -0.00974564 |
| CKM | creatine kinase, muscle | -0.0096925 |
| NRCAM | neuronal cell adhesion molecule | -0.00968359 |
| TTN | titin | -0.00967561 |
| RRAGD | Ras-related GTP binding D | -0.00961973 |
| CRABP2 | cellular retinoic acid binding protein 2 | -0.00959664 |
| TRIM22 | tripartite motif containing 22 | -0.00959103 |
| STC1 | stanniocalcin 1 | -0.0095417 |
| SCGB2A2 | secretoglobin, family 2A, member 2 | -0.00951744 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 | -0.00951189 |
| CLTB | clathrin, light chain B | -0.00950323 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) | -0.00948041 |
| LXN | latexin | -0.00945484 |
| MITF | microphthalmia-associated transcription factor | -0.00936653 |
| FHL2 | four and a half LIM domains 2 | -0.00931676 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | -0.0093014 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.00926299 |
| MET | MET proto-oncogene, receptor tyrosine kinase | -0.00922503 |
| ASS1 | argininosuccinate synthase 1 | -0.00920055 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa | -0.00915222 |
| GPNMB | glycoprotein (transmembrane) nmb | -0.00914401 |
| VEGFA | vascular endothelial growth factor A | -0.00914269 |
| AMOTL2 | angiomotin like 2 | -0.00910335 |
| CHIC2 | cysteine-rich hydrophobic domain 2 | -0.00908669 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | -0.00908287 |
| MAGEA3 | melanoma antigen family A3 | -0.00907422 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | -0.00904543 |
| KLHL41 | kelch-like family member 41 | -0.00902709 |
| KRT17 | keratin 17, type I | -0.0090023 |
| SCD5 | stearoyl-CoA desaturase 5 | -0.00898338 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.00895113 |
| UBE2L6 | ubiquitin-conjugating enzyme E2L 6 | -0.00890348 |
| XAF1 | XIAP associated factor 1 | -0.00881139 |
| SGCE | sarcoglycan, epsilon | -0.00879104 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | -0.00878571 |
| THBS1 | thrombospondin 1 | -0.00873616 |
| MYBPC1 | myosin binding protein C, slow type | -0.00870916 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | -0.00862117 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.00853537 |
| DYNLL1 | dynein, light chain, LC8-type 1 | -0.00850467 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | -0.00848388 |
| MYL2 | myosin, light chain 2, regulatory, cardiac, slow | -0.00847353 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.00845314 |
| SMAD3 | SMAD family member 3 | -0.00841951 |
| SLC2A5 | solute carrier family 2 (facilitated glucose/fructose transporter), member 5 | -0.00841652 |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 | -0.00839938 |
| MYL1 | myosin, light chain 1, alkali; skeletal, fast | -0.00838338 |
| DDX21 | DEAD (Asp-Glu-Ala-Asp) box helicase 21 | -0.008357 |
| SQSTM1 | sequestosome 1 | -0.00835617 |
| RGS4 | regulator of G-protein signaling 4 | -0.00827688 |
| H1-2 | H1.2 linker histone, cluster member | -0.00822765 |
| FBN2 | fibrillin 2 | -0.0082234 |
| IL32 | interleukin 32 | -0.00818883 |
| EMP1 | epithelial membrane protein 1 | -0.00817778 |
| CRABP1 | cellular retinoic acid binding protein 1 | -0.00817388 |
| VNN1 | vanin 1 | -0.00815023 |
| SLN | sarcolipin | -0.00813005 |
| PERP | PERP, TP53 apoptosis effector | -0.0081261 |
| C1S | complement component 1, s subcomponent | -0.00811516 |
| ADAMTS5 | ADAM metallopeptidase with thrombospondin type 1 motif, 5 | -0.0080972 |
| IRAG2 | inositol 1,4,5-triphosphate receptor associated 2 | -0.00808625 |
| FGF9 | fibroblast growth factor 9 | -0.00807229 |
| CYTH1 | cytohesin 1 | -0.00806957 |
| HMOX1 | heme oxygenase 1 | -0.008069 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.00806837 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.00805126 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 | -0.00804529 |
| PRSS23 | protease, serine, 23 | -0.00803955 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 | -0.00803678 |
| EGFL6 | EGF-like-domain, multiple 6 | -0.00803535 |
| TFRC | transferrin receptor | -0.00801192 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | -0.00800239 |
| TRAF3IP2 | TRAF3 interacting protein 2 | -0.0079405 |
| ARMCX3 | armadillo repeat containing, X-linked 3 | -0.0079218 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0079108 |
| PODXL | podocalyxin-like | -0.00790785 |
| ZFP36 | ZFP36 ring finger protein | -0.00787049 |
| ATP6V0E1 | ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1 | -0.00786287 |
| SCGB1D2 | secretoglobin, family 1D, member 2 | -0.00783802 |
| MBD2 | methyl-CpG binding domain protein 2 | -0.00781288 |
| DSP | desmoplakin | -0.00780959 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.007808 |
| SLPI | secretory leukocyte peptidase inhibitor | -0.00780124 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.00779916 |
| BTF3P11 | basic transcription factor 3 pseudogene 11 | -0.00777398 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.00777347 |
| SP110 | SP110 nuclear body protein | -0.00775036 |
| EEF1A2 | eukaryotic translation elongation factor 1 alpha 2 | -0.00774114 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.00772734 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F | -0.00770698 |
| GRAMD2B | GRAM domain containing 2B | -0.00768089 |
| FGB | fibrinogen beta chain | -0.0076758 |
| GBP2 | guanylate binding protein 2, interferon-inducible | -0.00762649 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | -0.00760042 |
| POLDIP2 | polymerase (DNA-directed), delta interacting protein 2 | -0.00759088 |
| PARP12 | poly (ADP-ribose) polymerase family, member 12 | -0.0075855 |
| UXT | ubiquitously-expressed, prefoldin-like chaperone | -0.00754921 |
| SIK1 | salt-inducible kinase 1 | -0.00754536 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.00751684 |
| ABHD4 | abhydrolase domain containing 4 | -0.00751054 |
| TNIP1 | TNFAIP3 interacting protein 1 | -0.00749611 |
| TMEM140 | transmembrane protein 140 | -0.0074868 |
| RGCC | regulator of cell cycle | -0.00747174 |
| FN1 | fibronectin 1 | -0.00745541 |
| AIM2 | absent in melanoma 2 | -0.0074552 |
| CDV3 | CDV3 homolog (mouse) | -0.00744647 |
| MME | membrane metallo-endopeptidase | -0.00744454 |
| UPK1B | uroplakin 1B | -0.00742473 |
| GEM | GTP binding protein overexpressed in skeletal muscle | -0.00741845 |
| CD79B | CD79b molecule, immunoglobulin-associated beta | -0.0074056 |
| NPC1 | Niemann-Pick disease, type C1 | -0.00740483 |
| PSG5 | pregnancy specific beta-1-glycoprotein 5 | -0.00737737 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.00737471 |
| MYO1B | myosin IB | -0.00737451 |
| DST | dystonin | -0.00736471 |
| FAM189A2 | family with sequence similarity 189, member A2 | -0.00736187 |
| ZNF395 | zinc finger protein 395 | -0.00733682 |
| SASH1 | SAM and SH3 domain containing 1 | -0.0073364 |
| HIST1H2AC | histone cluster 1, H2ac | -0.00732275 |
| PXDN | peroxidasin | -0.00731907 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0073097 |
| RGS2 | regulator of G-protein signaling 2 | -0.00727961 |
| IL6 | interleukin 6 | -0.00726513 |
| KLF4 | Kruppel-like factor 4 (gut) | -0.0072634 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0072472 |
| LAMB3 | laminin, beta 3 | -0.00724479 |
| PTHLH | parathyroid hormone-like hormone | -0.00723609 |
| HBEGF | heparin-binding EGF-like growth factor | -0.00723561 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.00723305 |
| CLCA4 | chloride channel accessory 4 | -0.00722855 |
| ATP6V1H | ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H | -0.00721325 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | -0.00720443 |
| MALL | mal, T-cell differentiation protein-like | -0.00718084 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | -0.00717082 |
| CAPN3 | calpain 3, (p94) | -0.00716752 |
| MBL2 | mannose-binding lectin (protein C) 2, soluble | -0.00715906 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | -0.00714601 |
| LY96 | lymphocyte antigen 96 | -0.00712863 |
| PALLD | palladin, cytoskeletal associated protein | -0.00712545 |
| CTSL | cathepsin L | -0.00712541 |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D | -0.00711608 |
| TAX1BP3 | Tax1 (human T-cell leukemia virus type I) binding protein 3 | -0.00711386 |
| RHCG | Rh family, C glycoprotein | -0.00710971 |
| ETFB | electron-transfer-flavoprotein, beta polypeptide | -0.0070983 |
| PLXNC1 | plexin C1 | -0.00704578 |
| COL15A1 | collagen, type XV, alpha 1 | -0.00703657 |
| ZFAND5 | zinc finger, AN1-type domain 5 | -0.00701572 |
| EPS8L2 | EPS8-like 2 | -0.00698789 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -0.00698027 |
| CIAO2B | cytosolic iron-sulfur assembly component 2B | -0.0069577 |
| HEG1 | heart development protein with EGF-like domains 1 | -0.00691653 |
| JMJD6 | jumonji domain containing 6 | -0.00690944 |
| BAMBI | BMP and activin membrane-bound inhibitor | -0.00690509 |
| HSPA2 | heat shock 70kDa protein 2 | -0.00690099 |
| ABLIM1 | actin binding LIM protein 1 | -0.00689158 |
| TRANK1 | tetratricopeptide repeat and ankyrin repeat containing 1 | -0.00687546 |
| KRT5 | keratin 5, type II | -0.00685423 |
| DDX58 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 | -0.00682258 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.00681073 |
| TNFRSF12A | tumor necrosis factor receptor superfamily, member 12A | -0.00680828 |
| KRT81 | keratin 81, type II | -0.00680818 |
| RGS13 | regulator of G-protein signaling 13 | -0.00680272 |
| VEGFC | vascular endothelial growth factor C | -0.00677072 |
| MCM2 | minichromosome maintenance complex component 2 | -0.00675869 |
| MXRA5 | matrix-remodelling associated 5 | -0.00675574 |
| CD163 | CD163 molecule | -0.0067431 |
| MTUS1 | microtubule associated tumor suppressor 1 | -0.00673678 |
| ACTA1 | actin, alpha 1, skeletal muscle | -0.00673451 |
