| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | carbonic anhydrase VIII|The protein encoded by this gene was initially named CA-related protein because of sequence similarity to other known carbonic anhydrase genes. However, the gene product lacks carbonic anhydrase activity (i.e., the reversible hydration of carbon dioxide). The gene product continues to carry a carbonic anhydrase designation based on clear sequence identity to other members of the carbonic anhydrase gene family. The absence of CA8 gene transcription in the cerebellum of the lurcher mutant in mice with a neurologic defect suggests an important role for this acatalytic form. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 767) |
| External Link | https://ncbi.nlm.nih.gov/gene/767 |
| Similar Terms | |
| Downloads & Tools |
497 genes differentially expressed following the CA8 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CASP10 | caspase 10, apoptosis-related cysteine peptidase | 0.0278046 |
| GNAS | GNAS complex locus | 0.0193131 |
| IFI44 | interferon-induced protein 44 | 0.0174212 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.017275 |
| MX1 | MX dynamin-like GTPase 1 | 0.0157517 |
| MYRF | myelin regulatory factor | 0.0137365 |
| IFI44L | interferon-induced protein 44-like | 0.0134033 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | 0.0129643 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | 0.0125309 |
| KLK10 | kallikrein-related peptidase 10 | 0.0124194 |
| IFITM1 | interferon induced transmembrane protein 1 | 0.0122594 |
| IFITM3 | interferon induced transmembrane protein 3 | 0.0116575 |
| LCN2 | lipocalin 2 | 0.0114693 |
| LAPTM4B | lysosomal protein transmembrane 4 beta | 0.0113636 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0113607 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | 0.0113061 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | 0.0112761 |
| ITGA6 | integrin, alpha 6 | 0.0111332 |
| LAMP3 | lysosomal-associated membrane protein 3 | 0.0110494 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.0107481 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0107196 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0106451 |
| DAPK1 | death-associated protein kinase 1 | 0.0106198 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 0.0105902 |
| KLK11 | kallikrein-related peptidase 11 | 0.010571 |
| USP18 | ubiquitin specific peptidase 18 | 0.010557 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.0105164 |
| PRKCA | protein kinase C, alpha | 0.0105112 |
| ANXA3 | annexin A3 | 0.0104285 |
| CD93 | CD93 molecule | 0.0103327 |
| NXN | nucleoredoxin | 0.0102857 |
| MX2 | MX dynamin-like GTPase 2 | 0.0102743 |
| MMP10 | matrix metallopeptidase 10 | 0.0102741 |
| REG3A | regenerating islet-derived 3 alpha | 0.0100868 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | 0.0100372 |
| FAM171A1 | family with sequence similarity 171, member A1 | 0.0100297 |
| CCN2 | cellular communication network factor 2 | 0.00995976 |
| TSPAN8 | tetraspanin 8 | 0.00995931 |
| NEFH | neurofilament, heavy polypeptide | 0.00994847 |
| FOSL2 | FOS-like antigen 2 | 0.00979376 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 | 0.00975129 |
| ASRGL1 | asparaginase like 1 | 0.00968186 |
| MDK | midkine (neurite growth-promoting factor 2) | 0.00962332 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 | 0.00960401 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 0.00935888 |
| SLC39A4 | solute carrier family 39 (zinc transporter), member 4 | 0.00930845 |
| DUOX2 | dual oxidase 2 | 0.00927148 |
| MUC16 | mucin 16, cell surface associated | 0.00925396 |
| PCP4 | Purkinje cell protein 4 | 0.00916324 |
| ECM1 | extracellular matrix protein 1 | 0.00908618 |
| CLIC5 | chloride intracellular channel 5 | 0.00906928 |
| CLEC2B | C-type lectin domain family 2, member B | 0.00905263 |
| TLCD3A | TLC domain containing 3A | 0.00904151 |
| CRIP1 | cysteine-rich protein 1 (intestinal) | 0.00896895 |
| OLFM4 | olfactomedin 4 | 0.00892466 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.00884876 |
| FRMD4B | FERM domain containing 4B | 0.00884506 |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 | 0.00884271 |
| RNF144A | ring finger protein 144A | 0.00877922 |
| CFI | complement factor I | 0.00866997 |
| IL1RN | interleukin 1 receptor antagonist | 0.00861684 |
| EHF | ets homologous factor | 0.00858856 |
| GAB2 | GRB2-associated binding protein 2 | 0.00858166 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.00857301 |
| ATF3 | activating transcription factor 3 | 0.00853781 |
| SCG5 | secretogranin V | 0.00848706 |
| COLEC12 | collectin sub-family member 12 | 0.00846836 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | 0.00838957 |
| IRS2 | insulin receptor substrate 2 | 0.00835962 |
| MTUS1 | microtubule associated tumor suppressor 1 | 0.00832661 |
| KIAA0100 | KIAA0100 | 0.00831278 |
| REG1A | regenerating islet-derived 1 alpha | 0.00825543 |
| SST | somatostatin | 0.00825119 |
| SOX17 | SRY (sex determining region Y)-box 17 | 0.00823238 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 0.00817988 |
| TRIP6 | thyroid hormone receptor interactor 6 | 0.00814749 |
| PELI2 | pellino E3 ubiquitin protein ligase family member 2 | 0.00805866 |
| HOXB2 | homeobox B2 | 0.00804348 |
| KLK7 | kallikrein-related peptidase 7 | 0.00802998 |
| PAK1 | p21 protein (Cdc42/Rac)-activated kinase 1 | 0.00801227 |
| HOXB6 | homeobox B6 | 0.00799883 |
| XAF1 | XIAP associated factor 1 | 0.00798958 |
| MEN1 | multiple endocrine neoplasia I | 0.0079884 |
| SIK1 | salt-inducible kinase 1 | 0.00792679 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | 0.00791931 |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit | 0.00791162 |
| DDX58 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 | 0.00789117 |
| THBS1 | thrombospondin 1 | 0.00788227 |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 | 0.00785328 |
| PLAU | plasminogen activator, urokinase | 0.00783573 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | 0.00780281 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | 0.00778743 |
| AOC1 | amine oxidase, copper containing 1 | 0.00778702 |
| C6ORF48 | chromosome 6 open reading frame 48 | 0.00777856 |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | 0.00770984 |
| CFB | complement factor B | 0.00770937 |
| APLP1 | amyloid beta (A4) precursor-like protein 1 | 0.00766481 |
| ZDHHC11 | zinc finger, DHHC-type containing 11 | 0.0076211 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.00755372 |
| CHGB | chromogranin B | 0.00755068 |
| LAMB1 | laminin, beta 1 | 0.00752322 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.00750176 |
| GJA1 | gap junction protein, alpha 1, 43kDa | 0.00750087 |
| COL18A1 | collagen, type XVIII, alpha 1 | 0.00749094 |
| EDNRA | endothelin receptor type A | 0.0074841 |
| GREB1 | growth regulation by estrogen in breast cancer 1 | 0.00746821 |
| PGGHG | protein-glucosylgalactosylhydroxylysine glucosidase | 0.00744132 |
| ACTB | actin, beta | 0.00740132 |
| TMPRSS2 | transmembrane protease, serine 2 | 0.00736857 |
| SORD | sorbitol dehydrogenase | 0.00735657 |
| CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 | 0.00732566 |
| DNAJC12 | DnaJ (Hsp40) homolog, subfamily C, member 12 | 0.00728695 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.00728669 |
| NCF2 | neutrophil cytosolic factor 2 | 0.00724865 |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 | 0.00720757 |
| AQP3 | aquaporin 3 (Gill blood group) | 0.00719756 |
| INAVA | innate immunity activator | 0.00718236 |
| TMC5 | transmembrane channel-like 5 | 0.00716395 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.00712295 |
| LRRN3 | leucine rich repeat neuronal 3 | 0.00711257 |
| KLK5 | kallikrein-related peptidase 5 | 0.00710092 |
| ATP10B | ATPase, class V, type 10B | 0.00709307 |
| CLDN1 | claudin 1 | 0.00706727 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.00706146 |
| MMP11 | matrix metallopeptidase 11 | 0.00703061 |
| H1-0 | H1.0 linker histone | 0.00695768 |
| KLK8 | kallikrein-related peptidase 8 | 0.00693153 |
| MECOM | MDS1 and EVI1 complex locus | 0.00691317 |
| OLFML2A | olfactomedin-like 2A | 0.0069089 |
| PRAME | preferentially expressed antigen in melanoma | 0.00688065 |
| IFITM2 | interferon induced transmembrane protein 2 | 0.00687593 |
| TMEFF1 | transmembrane protein with EGF-like and two follistatin-like domains 1 | 0.00684013 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.00680918 |
| LRIG1 | leucine-rich repeats and immunoglobulin-like domains 1 | 0.00678754 |
| GMPR | guanosine monophosphate reductase | 0.00677286 |
| MSLN | mesothelin | 0.00676646 |
| LGALS13 | lectin, galactoside-binding, soluble, 13 | 0.00674834 |
| BAZ2B | bromodomain adjacent to zinc finger domain, 2B | 0.00672859 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | 0.00669389 |
| LAMP5 | lysosomal-associated membrane protein family, member 5 | 0.00668239 |
| EMP1 | epithelial membrane protein 1 | 0.00668239 |
| EVI2A | ecotropic viral integration site 2A | 0.00667519 |
| NPY | neuropeptide Y | 0.00667214 |
| NID1 | nidogen 1 | 0.00666091 |
| C5AR1 | complement component 5a receptor 1 | 0.00665458 |
| IRF7 | interferon regulatory factor 7 | 0.00661518 |
| EGFL6 | EGF-like-domain, multiple 6 | 0.0066138 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | 0.00660481 |
| GBP1 | guanylate binding protein 1, interferon-inducible | 0.0065378 |
| GRK5 | G protein-coupled receptor kinase 5 | 0.00651941 |
| CCNB1IP1 | cyclin B1 interacting protein 1, E3 ubiquitin protein ligase | 0.00650689 |
| CNTN1 | contactin 1 | 0.00649514 |
| ESRP1 | epithelial splicing regulatory protein 1 | 0.00647459 |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D | 0.00645795 |
| IRF9 | interferon regulatory factor 9 | 0.00642088 |
| FAM198B | family with sequence similarity 198, member B | 0.00640414 |
| ABLIM1 | actin binding LIM protein 1 | 0.00638579 |
| ACKR3 | atypical chemokine receptor 3 | 0.00638475 |
| PIEZO2 | piezo-type mechanosensitive ion channel component 2 | 0.00638013 |
| SPON1 | spondin 1, extracellular matrix protein | 0.00637397 |
| MMP12 | matrix metallopeptidase 12 | 0.00635961 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | 0.00635574 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 | 0.00635343 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.00634793 |
| SMAD3 | SMAD family member 3 | 0.0063433 |
| PTP4A1 | protein tyrosine phosphatase type IVA, member 1 | 0.00634131 |
| HNMT | histamine N-methyltransferase | 0.00633828 |
| STMN2 | stathmin 2 | 0.00630652 |
| EPYC | epiphycan | 0.00629855 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.0062946 |
| ST18 | suppression of tumorigenicity 18, zinc finger | 0.00628251 |
| FRS2 | fibroblast growth factor receptor substrate 2 | 0.00626141 |
| MAL | mal, T-cell differentiation protein | 0.0062404 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | 0.00622947 |
| SUPT6H | suppressor of Ty 6 homolog (S. cerevisiae) | 0.00622817 |
| LPAR6 | lysophosphatidic acid receptor 6 | 0.00621372 |
| SAMHD1 | SAM domain and HD domain 1 | 0.00617754 |
| CASP1 | caspase 1, apoptosis-related cysteine peptidase | 0.00617525 |
| CDR2L | cerebellar degeneration-related protein 2-like | 0.00617065 |
| DEFB1 | defensin, beta 1 | 0.00614104 |
| SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) | 0.00610941 |
| TFF1 | trefoil factor 1 | 0.00610628 |
| AHCYL1 | adenosylhomocysteinase-like 1 | 0.00608969 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.00608965 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.00608922 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0060764 |
| F2RL1 | coagulation factor II (thrombin) receptor-like 1 | 0.00605053 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 0.00601601 |
| CDH17 | cadherin 17, LI cadherin (liver-intestine) | 0.00600526 |
| DEFA6 | defensin, alpha 6, Paneth cell-specific | 0.0059941 |
| CHKB | choline kinase beta | 0.00599159 |
| ARRB2 | arrestin, beta 2 | 0.00598423 |
| TWIST1 | twist family bHLH transcription factor 1 | 0.00598073 |
| STON1 | stonin 1 | 0.00597829 |
| PDZK1IP1 | PDZK1 interacting protein 1 | 0.00597338 |
| FA2H | fatty acid 2-hydroxylase | 0.00596212 |
| THEMIS2 | thymocyte selection associated family member 2 | 0.00594853 |
| DACH1 | dachshund family transcription factor 1 | 0.00594221 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.00593308 |
| FZD5 | frizzled class receptor 5 | 0.00591677 |
| CCL14 | chemokine (C-C motif) ligand 14 | 0.00591539 |
| DENND5A | DENN/MADD domain containing 5A | 0.00590711 |
| PLLP | plasmolipin | 0.00589097 |
| MFNG | MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase | 0.00588369 |
| RAB23 | RAB23, member RAS oncogene family | 0.00588308 |
| PUF60 | poly-U binding splicing factor 60KDa | 0.00588077 |
| IVNS1ABP | influenza virus NS1A binding protein | 0.0058677 |
| NMU | neuromedin U | 0.00585006 |
| MAN1C1 | mannosidase, alpha, class 1C, member 1 | 0.0058397 |
| DLST | dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) | 0.00581003 |
| APOL6 | apolipoprotein L, 6 | 0.00580317 |
| NPR1 | natriuretic peptide receptor 1 | 0.00578199 |
| OASL | 2'-5'-oligoadenylate synthetase-like | 0.00576927 |
| MSX1 | msh homeobox 1 | 0.00576754 |
| MARCKSL1 | MARCKS-like 1 | 0.00576366 |
| TMPRSS4 | transmembrane protease, serine 4 | 0.00575786 |
| CTSS | cathepsin S | 0.00574771 |
| WT1 | Wilms tumor 1 | 0.00573734 |
| C21ORF91 | chromosome 21 open reading frame 91 | 0.00573504 |
| SCEL | sciellin | 0.00573268 |
| TMEM35 | transmembrane protein 35 | 0.00572839 |
| MUC4 | mucin 4, cell surface associated | 0.00570185 |
| RNF167 | ring finger protein 167 | 0.00568859 |
| TADA2A | transcriptional adaptor 2A | 0.00568077 |
| EPS8L1 | EPS8-like 1 | 0.00566789 |
| CIAPIN1 | cytokine induced apoptosis inhibitor 1 | 0.00564964 |
| ANTXR1 | anthrax toxin receptor 1 | 0.00564766 |
| HOXD1 | homeobox D1 | 0.00563794 |
| COL4A6 | collagen, type IV, alpha 6 | 0.00561793 |
| SLC47A1 | solute carrier family 47 (multidrug and toxin extrusion), member 1 | 0.00561035 |
| TBC1D31 | TBC1 domain family, member 31 | 0.00560949 |
| CTSV | cathepsin V | 0.00559849 |
| PDZRN3 | PDZ domain containing ring finger 3 | 0.00559616 |
| ACP3 | acid phosphatase 3 | 0.00559037 |
| GALNT12 | polypeptide N-acetylgalactosaminyltransferase 12 | 0.00558011 |
| TRIM16 | tripartite motif containing 16 | 0.00557203 |
| CX3CL1 | chemokine (C-X3-C motif) ligand 1 | 0.00556891 |
| DAXX | death-domain associated protein | 0.00556677 |
| HPSE | heparanase | 0.00556069 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 0.00555623 |
| ARG2 | arginase 2 | 0.00554013 |
| PTGER2 | prostaglandin E receptor 2 (subtype EP2), 53kDa | 0.00553943 |
| WLS | wntless Wnt ligand secretion mediator | 0.00553543 |
| NDST1 | N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 | 0.00553307 |
| ESR1 | estrogen receptor 1 | 0.00553077 |
| HOXB7 | homeobox B7 | 0.00552798 |
| ATF4 | activating transcription factor 4 | 0.00551608 |
| PHACTR4 | phosphatase and actin regulator 4 | 0.00549153 |
| MEIS2 | Meis homeobox 2 | 0.00548726 |
| PCSK1 | proprotein convertase subtilisin/kexin type 1 | 0.00547555 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CLU | clusterin | -0.0157914 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0157249 |
| METTL7A | methyltransferase like 7A | -0.013105 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | -0.0129376 |
| CXCL13 | chemokine (C-X-C motif) ligand 13 | -0.0121134 |
| CXCL12 | chemokine (C-X-C motif) ligand 12 | -0.0109217 |
| CCL19 | chemokine (C-C motif) ligand 19 | -0.0106552 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 | -0.0103997 |
| CD59 | CD59 molecule, complement regulatory protein | -0.0102357 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | -0.00982401 |
| KRT23 | keratin 23, type I | -0.00980606 |
| RB1 | retinoblastoma 1 | -0.00969077 |
| HMGCS2 | 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) | -0.00947245 |
| POSTN | periostin, osteoblast specific factor | -0.00930945 |
| CST3 | cystatin C | -0.00921116 |
| NOTCH2NL | notch 2 N-terminal like | -0.0092047 |
| NPY1R | neuropeptide Y receptor Y1 | -0.00920112 |
| DENND2D | DENN/MADD domain containing 2D | -0.00916864 |
| CGA | glycoprotein hormones, alpha polypeptide | -0.0089347 |
| CST7 | cystatin F (leukocystatin) | -0.00889376 |
| JCHAIN | joining chain of multimeric IgA and IgM | -0.00882707 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.00880028 |
| RAP2A | RAP2A, member of RAS oncogene family | -0.0087582 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 | -0.00871068 |
| STEAP3 | STEAP family member 3, metalloreductase | -0.00869504 |
| CCL5 | chemokine (C-C motif) ligand 5 | -0.00856518 |
| SLC38A1 | solute carrier family 38, member 1 | -0.00854609 |
| ITM2A | integral membrane protein 2A | -0.0085366 |
| ELF5 | E74-like factor 5 (ets domain transcription factor) | -0.00844969 |
| UGT2B28 | UDP glucuronosyltransferase 2 family, polypeptide B28 | -0.00838147 |
| VCAM1 | vascular cell adhesion molecule 1 | -0.00834923 |
| MAGEA3 | melanoma antigen family A3 | -0.0081603 |
| PROM1 | prominin 1 | -0.00812536 |
| PAX5 | paired box 5 | -0.00810533 |
| SERPING1 | serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 | -0.00806338 |
| ADIRF | adipogenesis regulatory factor | -0.00792037 |
| MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 | -0.00791148 |
| GZMA | granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) | -0.00790213 |
| DHDDS | dehydrodolichyl diphosphate synthase | -0.00790155 |
| KRAS | Kirsten rat sarcoma viral oncogene homolog | -0.0078839 |
| LYZ | lysozyme | -0.00780827 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 | -0.00764455 |
| CA12 | carbonic anhydrase XII | -0.00763727 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) | -0.00763532 |
| NOTCH2 | notch 2 | -0.00758401 |
| MMP9 | matrix metallopeptidase 9 | -0.00757536 |
| KRT14 | keratin 14, type I | -0.00754467 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 | -0.00754315 |
| GZMK | granzyme K (granzyme 3; tryptase II) | -0.00753909 |
| BTF3P11 | basic transcription factor 3 pseudogene 11 | -0.0075289 |
| HMGB3 | high mobility group box 3 | -0.00752723 |
| CYB5A | cytochrome b5 type A (microsomal) | -0.00752207 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.00750265 |
| GOLGA8A | golgin A8 family, member A | -0.00746174 |
| PCOLCE2 | procollagen C-endopeptidase enhancer 2 | -0.00738747 |
| CTSW | cathepsin W | -0.00736745 |
| CKS2 | CDC28 protein kinase regulatory subunit 2 | -0.00727448 |
| FKBP11 | FK506 binding protein 11, 19 kDa | -0.00725707 |
| NNMT | nicotinamide N-methyltransferase | -0.00714627 |
| E2F2 | E2F transcription factor 2 | -0.00713357 |
| RNF128 | ring finger protein 128, E3 ubiquitin protein ligase | -0.00711086 |
| NKG7 | natural killer cell granule protein 7 | -0.00708168 |
| DBF4 | DBF4 zinc finger | -0.00707925 |
| IRAG2 | inositol 1,4,5-triphosphate receptor associated 2 | -0.00702442 |
| PTHLH | parathyroid hormone-like hormone | -0.00701727 |
| CDK14 | cyclin-dependent kinase 14 | -0.00687368 |
| SMYD2 | SET and MYND domain containing 2 | -0.00681726 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C | -0.00679419 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 | -0.00678987 |
| NETO2 | neuropilin (NRP) and tolloid (TLL)-like 2 | -0.00677543 |
| CCL21 | chemokine (C-C motif) ligand 21 | -0.00675852 |
| SRPX | sushi-repeat containing protein, X-linked | -0.00674111 |
| MGP | matrix Gla protein | -0.00673373 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.00673335 |
| TSPAN5 | tetraspanin 5 | -0.00670584 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | -0.00668495 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.00665153 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | -0.00663073 |
| PFN2 | profilin 2 | -0.00662504 |
| CDK13 | cyclin-dependent kinase 13 | -0.00662493 |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha | -0.00659901 |
| PRF1 | perforin 1 (pore forming protein) | -0.00658217 |
| TWF1 | twinfilin actin binding protein 1 | -0.00654308 |
| ZNF91 | zinc finger protein 91 | -0.00651747 |
| TFF3 | trefoil factor 3 (intestinal) | -0.00646147 |
| SLC26A2 | solute carrier family 26 (anion exchanger), member 2 | -0.00643678 |
| TPSAB1 | tryptase alpha/beta 1 | -0.00643227 |
| MS4A1 | membrane-spanning 4-domains, subfamily A, member 1 | -0.00629099 |
| SKAP2 | src kinase associated phosphoprotein 2 | -0.00629019 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | -0.00628148 |
| TSPO | translocator protein (18kDa) | -0.00626854 |
| STC2 | stanniocalcin 2 | -0.00626172 |
| FAM172A | family with sequence similarity 172, member A | -0.00625439 |
| CSTA | cystatin A (stefin A) | -0.00625331 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | -0.00623134 |
| RADX | RPA1 related single stranded DNA binding protein, X-linked | -0.00622456 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.00622448 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | -0.00620446 |
| TMX4 | thioredoxin-related transmembrane protein 4 | -0.0062017 |
| DACT1 | dishevelled-binding antagonist of beta-catenin 1 | -0.00616653 |
| ZNF160 | zinc finger protein 160 | -0.00614978 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 | -0.00612773 |
| SYNE1 | spectrin repeat containing, nuclear envelope 1 | -0.00610418 |
| APMAP | adipocyte plasma membrane associated protein | -0.00607431 |
| LCK | LCK proto-oncogene, Src family tyrosine kinase | -0.00606856 |
| COMT | catechol-O-methyltransferase | -0.00605955 |
| CSF2RB | colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) | -0.00605711 |
| TMEM134 | transmembrane protein 134 | -0.00605124 |
| EVA1B | eva-1 homolog B (C. elegans) | -0.006051 |
| PHTF2 | putative homeodomain transcription factor 2 | -0.00604043 |
| ACKR1 | atypical chemokine receptor 1 (Duffy blood group) | -0.0060349 |
| CD9 | CD9 molecule | -0.00602331 |
| PERP | PERP, TP53 apoptosis effector | -0.00600716 |
| POU2AF1 | POU class 2 associating factor 1 | -0.00596709 |
| CD320 | CD320 molecule | -0.0059624 |
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | -0.00595738 |
| HSPB8 | heat shock 22kDa protein 8 | -0.00595588 |
| SPINK2 | serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) | -0.00592088 |
| MREG | melanoregulin | -0.00591549 |
| CXORF40B | chromosome X open reading frame 40B | -0.00591137 |
| PDGFRL | platelet-derived growth factor receptor-like | -0.00590693 |
| FAM46C | family with sequence similarity 46, member C | -0.00590484 |
| TMEM87A | transmembrane protein 87A | -0.00589806 |
| TRAPPC3 | trafficking protein particle complex 3 | -0.00587971 |
| PLXNA1 | plexin A1 | -0.00587969 |
| DIPK1A | divergent protein kinase domain 1A | -0.00587001 |
| S100P | S100 calcium binding protein P | -0.00586819 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 | -0.00586379 |
| TAGLN | transgelin | -0.0058636 |
| CEP170 | centrosomal protein 170kDa | -0.00585876 |
| PTPRCAP | protein tyrosine phosphatase, receptor type, C-associated protein | -0.00585716 |
| JAG1 | jagged 1 | -0.00584574 |
| XCL1 | chemokine (C motif) ligand 1 | -0.00582913 |
| CIB1 | calcium and integrin binding 1 (calmyrin) | -0.00580342 |
| IL7 | interleukin 7 | -0.00578871 |
| MAGEA12 | melanoma antigen family A12 | -0.00578498 |
| GALNT1 | polypeptide N-acetylgalactosaminyltransferase 1 | -0.00577445 |
| KRR1 | KRR1, small subunit (SSU) processome component, homolog (yeast) | -0.00576321 |
| DGKZ | diacylglycerol kinase, zeta | -0.00575977 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.00575522 |
| WWC3 | WWC family member 3 | -0.00574315 |
| SMS | spermine synthase | -0.00571831 |
| TSPAN13 | tetraspanin 13 | -0.00569591 |
| C1S | complement component 1, s subcomponent | -0.0056956 |
| FAM3C | family with sequence similarity 3, member C | -0.00567348 |
| MTCL1 | microtubule crosslinking factor 1 | -0.0056581 |
| ZNF721 | zinc finger protein 721 | -0.00564841 |
| NT5DC2 | 5'-nucleotidase domain containing 2 | -0.00564255 |
| ATP10D | ATPase, class V, type 10D | -0.00561203 |
| LETM1 | leucine zipper-EF-hand containing transmembrane protein 1 | -0.00560127 |
| DSE | dermatan sulfate epimerase | -0.00560015 |
| GRAMD1B | GRAM domain containing 1B | -0.00557594 |
| SLC37A4 | solute carrier family 37 (glucose-6-phosphate transporter), member 4 | -0.00557133 |
| TCF4 | transcription factor 4 | -0.00556985 |
| SCGB2A2 | secretoglobin, family 2A, member 2 | -0.005562 |
| AHSP | alpha hemoglobin stabilizing protein | -0.00556101 |
| BPGM | 2,3-bisphosphoglycerate mutase | -0.00552651 |
| IDS | iduronate 2-sulfatase | -0.00551978 |
| BSG | basigin (Ok blood group) | -0.00551071 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.00550581 |
| APOBEC3B | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B | -0.00549843 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.00549102 |
| RGS13 | regulator of G-protein signaling 13 | -0.00548761 |
| SLC39A6 | solute carrier family 39 (zinc transporter), member 6 | -0.00546658 |
| PRR11 | proline rich 11 | -0.00545785 |
| VPS13A | vacuolar protein sorting 13 homolog A (S. cerevisiae) | -0.0054567 |
| C4BPA | complement component 4 binding protein, alpha | -0.00545541 |
| LDOC1 | leucine zipper, down-regulated in cancer 1 | -0.00543485 |
| COX17 | COX17 cytochrome c oxidase copper chaperone | -0.00540669 |
| ROPN1B | rhophilin associated tail protein 1B | -0.00540266 |
| MAPT | microtubule-associated protein tau | -0.00539787 |
| CXORF40A | chromosome X open reading frame 40A | -0.00539257 |
| ITIH3 | inter-alpha-trypsin inhibitor heavy chain 3 | -0.00538087 |
| HAPLN1 | hyaluronan and proteoglycan link protein 1 | -0.00537574 |
| FABP4 | fatty acid binding protein 4, adipocyte | -0.00537434 |
| MYH11 | myosin, heavy chain 11, smooth muscle | -0.00537188 |
| SPIB | Spi-B transcription factor (Spi-1/PU.1 related) | -0.00535787 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.00535339 |
| KANK1 | KN motif and ankyrin repeat domains 1 | -0.00535225 |
| FAM234B | family with sequence similarity 234 member B | -0.00534757 |
| C2CD5 | C2 calcium-dependent domain containing 5 | -0.00532164 |
| TIMM17B | translocase of inner mitochondrial membrane 17 homolog B (yeast) | -0.00530522 |
| CALML3 | calmodulin-like 3 | -0.00530201 |
| FCMR | Fc fragment of IgM receptor | -0.00528432 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.00526437 |
| C1QB | complement component 1, q subcomponent, B chain | -0.00524567 |
| EHHADH | enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase | -0.0052439 |
| FIG4 | FIG4 phosphoinositide 5-phosphatase | -0.00523851 |
| KAT2B | K(lysine) acetyltransferase 2B | -0.00523162 |
| CD8A | CD8a molecule | -0.00523053 |
| UGT2A3 | UDP glucuronosyltransferase 2 family, polypeptide A3 | -0.00522924 |
| PFDN4 | prefoldin subunit 4 | -0.00522053 |
| GZMB | granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) | -0.00521625 |
| CFH | complement factor H | -0.00521426 |
| NDUFA7 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa | -0.00521238 |
| SCAND1 | SCAN domain containing 1 | -0.00521053 |
| QSOX1 | quiescin Q6 sulfhydryl oxidase 1 | -0.00520749 |
| ABCD3 | ATP-binding cassette, sub-family D (ALD), member 3 | -0.00518913 |
| STX7 | syntaxin 7 | -0.00518606 |
| MAPK13 | mitogen-activated protein kinase 13 | -0.00516809 |
| P2RX5 | purinergic receptor P2X, ligand gated ion channel, 5 | -0.00514758 |
| DKFZP586I1420 | uncharacterized protein DKFZp586I1420 | -0.00514543 |
| S100A11 | S100 calcium binding protein A11 | -0.00513995 |
| LPCAT1 | lysophosphatidylcholine acyltransferase 1 | -0.0051304 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 | -0.00512639 |
| HAUS2 | HAUS augmin-like complex, subunit 2 | -0.00512028 |
| HOXC10 | homeobox C10 | -0.00511487 |
| TMEM14A | transmembrane protein 14A | -0.00510567 |
| NDUFA4L2 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2 | -0.00509141 |
| ZNF148 | zinc finger protein 148 | -0.00508737 |
| SCAF4 | SR-related CTD-associated factor 4 | -0.00508172 |
| TTN | titin | -0.00508057 |
| ING3 | inhibitor of growth family, member 3 | -0.00508009 |
| CPA3 | carboxypeptidase A3 (mast cell) | -0.00507792 |
| NME3 | NME/NM23 nucleoside diphosphate kinase 3 | -0.00506418 |
| EIF2D | eukaryotic translation initiation factor 2D | -0.00506036 |
| KRT15 | keratin 15, type I | -0.00505932 |
| BAMBI | BMP and activin membrane-bound inhibitor | -0.00505574 |
| CD36 | CD36 molecule (thrombospondin receptor) | -0.00505079 |
| BCL11A | B-cell CLL/lymphoma 11A (zinc finger protein) | -0.00505012 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.00504735 |
| CRABP1 | cellular retinoic acid binding protein 1 | -0.00503226 |
| PTN | pleiotrophin | -0.00503185 |
| TAF5 | TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 100kDa | -0.00501107 |
| HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 | -0.00500096 |
| SLC25A14 | solute carrier family 25 (mitochondrial carrier, brain), member 14 | -0.00498082 |
| TP63 | tumor protein p63 | -0.00496424 |
| FAM174B | family with sequence similarity 174, member B | -0.00494422 |
| BMP2K | BMP2 inducible kinase | -0.00492906 |
| GPR137B | G protein-coupled receptor 137B | -0.00490799 |
| OCRL | oculocerebrorenal syndrome of Lowe | -0.00489586 |
| WDR61 | WD repeat domain 61 | -0.00488422 |
| FMO2 | flavin containing monooxygenase 2 (non-functional) | -0.00488074 |
| TMEM45A | transmembrane protein 45A | -0.00487991 |
| GZMH | granzyme H (cathepsin G-like 2, protein h-CCPX) | -0.00487641 |
| TCTA | T-cell leukemia translocation altered | -0.00486139 |
| CD19 | CD19 molecule | -0.00485236 |
| BCL7B | B-cell CLL/lymphoma 7B | -0.00484668 |
| ITGA7 | integrin, alpha 7 | -0.00484031 |
| COMMD8 | COMM domain containing 8 | -0.00483527 |
| RPA3 | replication protein A3, 14kDa | -0.00481786 |
| COG2 | component of oligomeric golgi complex 2 | -0.00481068 |
| COBL | cordon-bleu WH2 repeat protein | -0.00480765 |
| ADAMDEC1 | ADAM-like, decysin 1 | -0.00480029 |
| RASGRP1 | RAS guanyl releasing protein 1 (calcium and DAG-regulated) | -0.00479871 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | -0.00478855 |
| ALAS2 | 5'-aminolevulinate synthase 2 | -0.00478643 |
