| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | calcium channel, voltage-dependent, P/Q type, alpha 1A subunit|Voltage-dependent calcium channels mediate the entry of calcium ions into excitable cells, and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, and gene expression. Calcium channels are multisubunit complexes composed of alpha-1, beta, alpha-2/delta, and gamma subunits. The channel activity is directed by the pore-forming alpha-1 subunit, whereas, the others act as auxiliary subunits regulating this activity. The distinctive properties of the calcium channel types are related primarily to the expression of a variety of alpha-1 isoforms, alpha-1A, B, C, D, E, and S. This gene encodes the alpha-1A subunit, which is predominantly expressed in neuronal tissue. Mutations in this gene are associated with 2 neurologic disorders, familial hemiplegic migraine and episodic ataxia 2. This gene also exhibits polymorphic variation due to (CAG)n-repeats. Multiple transcript variants encoding different isoforms have been found for this gene. In one set of transcript variants, the (CAG)n-repeats occur in the 3' UTR, and are not associated with any disease. But in another set of variants, an insertion extends the coding region to include the (CAG)n-repeats which encode a polyglutamine tract. Expansion of the (CAG)n-repeats from the normal 4-16 to 21-28 in the coding region is associated with spinocerebellar ataxia 6. [provided by RefSeq, Mar 2010] (NCBI Entrez Gene Database, 773) |
| External Link | https://ncbi.nlm.nih.gov/gene/773 |
| Similar Terms | |
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498 genes differentially expressed following the CACNA1A gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HAL | histidine ammonia-lyase | 0.0135731 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.0135245 |
| GNAS | GNAS complex locus | 0.0131024 |
| XIC | X chromosome inactivation center | 0.0126556 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 0.0123269 |
| XPO7 | exportin 7 | 0.0122695 |
| GPM6B | glycoprotein M6B | 0.0118466 |
| AQP3 | aquaporin 3 (Gill blood group) | 0.0108422 |
| IRS2 | insulin receptor substrate 2 | 0.0105406 |
| TYRP1 | tyrosinase-related protein 1 | 0.0103581 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | 0.0102675 |
| KIAA0100 | KIAA0100 | 0.0100964 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.00993025 |
| TUBB2B | tubulin, beta 2B class IIb | 0.00976489 |
| NIBAN1 | niban apoptosis regulator 1 | 0.00976339 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.00970438 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.009668 |
| HSPA1A | heat shock 70kDa protein 1A | 0.00965302 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | 0.00953637 |
| SLPI | secretory leukocyte peptidase inhibitor | 0.00952404 |
| DDIT3 | DNA-damage-inducible transcript 3 | 0.00936026 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.00934861 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.00926856 |
| OXTR | oxytocin receptor | 0.00925387 |
| DDX21 | DEAD (Asp-Glu-Ala-Asp) box helicase 21 | 0.00917757 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | 0.00916276 |
| PKD1P1 | polycystic kidney disease 1 (autosomal dominant) pseudogene 1 | 0.00914566 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | 0.00911793 |
| FLRT3 | fibronectin leucine rich transmembrane protein 3 | 0.00905762 |
| MT1X | metallothionein 1X | 0.00899107 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.00882295 |
| SCG5 | secretogranin V | 0.00881547 |
| MT2A | metallothionein 2A | 0.00862237 |
| KRT1 | keratin 1, type II | 0.00855482 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.00846972 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.00841993 |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 | 0.00837879 |
| LAMP3 | lysosomal-associated membrane protein 3 | 0.00837643 |
| SCUBE2 | signal peptide, CUB domain, EGF-like 2 | 0.00834683 |
| SYBU | syntabulin (syntaxin-interacting) | 0.00833646 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | 0.00830266 |
| EIF5A | eukaryotic translation initiation factor 5A | 0.00830028 |
| PSAT1 | phosphoserine aminotransferase 1 | 0.00828901 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 | 0.00825235 |
| MT1HL1 | metallothionein 1H-like 1 | 0.00824513 |
| VLDLR | very low density lipoprotein receptor | 0.00809764 |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) | 0.00807837 |
| GPC3 | glypican 3 | 0.00801959 |
| INHBE | inhibin, beta E | 0.00798782 |
| NAV2 | neuron navigator 2 | 0.00796532 |
| MYH10 | myosin, heavy chain 10, non-muscle | 0.00794283 |
| ABLIM1 | actin binding LIM protein 1 | 0.007902 |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) | 0.00785664 |
| CNTN1 | contactin 1 | 0.00779807 |
| ATIC | 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase | 0.00776055 |
| NPIPA1 | nuclear pore complex interacting protein family, member A1 | 0.00773593 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.00771753 |
| DEFB1 | defensin, beta 1 | 0.00768469 |
| FGG | fibrinogen gamma chain | 0.0076721 |
| MT1E | metallothionein 1E | 0.00765539 |
| PXDN | peroxidasin | 0.00765301 |
| LMO3 | LIM domain only 3 (rhombotin-like 2) | 0.00757276 |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | 0.00756474 |
| ZNF318 | zinc finger protein 318 | 0.0075092 |
| FN1 | fibronectin 1 | 0.00745314 |
| HOMER1 | homer scaffolding protein 1 | 0.00742372 |
| EIF5B | eukaryotic translation initiation factor 5B | 0.00741014 |
| CRABP1 | cellular retinoic acid binding protein 1 | 0.00735375 |
| ZFAND5 | zinc finger, AN1-type domain 5 | 0.0073427 |
| MT1H | metallothionein 1H | 0.00733997 |
| ZNF160 | zinc finger protein 160 | 0.00731959 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | 0.00731384 |
| SARS1 | seryl-tRNA synthetase 1 | 0.00726743 |
| S100A7 | S100 calcium binding protein A7 | 0.00726106 |
| DDR2 | discoidin domain receptor tyrosine kinase 2 | 0.00722866 |
| IER5 | immediate early response 5 | 0.00721109 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.00719546 |
| PIK3CD | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta | 0.00718486 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | 0.00718345 |
| C14ORF132 | chromosome 14 open reading frame 132 | 0.00710094 |
| ATF3 | activating transcription factor 3 | 0.00709249 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | 0.00708749 |
| ANXA1 | annexin A1 | 0.00706873 |
| FABP7 | fatty acid binding protein 7, brain | 0.00704727 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 0.007047 |
| RET | ret proto-oncogene | 0.006999 |
| SLC18A1 | solute carrier family 18 (vesicular monoamine transporter), member 1 | 0.00698923 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.00698365 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | 0.00696565 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | 0.00696558 |
| DTX4 | deltex 4, E3 ubiquitin ligase | 0.00695566 |
| ASS1 | argininosuccinate synthase 1 | 0.00695341 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 0.00695135 |
| EGR1 | early growth response 1 | 0.00694941 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | 0.00689516 |
| NEBL | nebulette | 0.00688475 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.00688034 |
| TMEFF1 | transmembrane protein with EGF-like and two follistatin-like domains 1 | 0.00684317 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.00680174 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.00679903 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.00679075 |
| ATP1A2 | ATPase, Na+/K+ transporting, alpha 2 polypeptide | 0.00675183 |
| CSRP2 | cysteine and glycine-rich protein 2 | 0.00670457 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | 0.00667403 |
| KCNJ16 | potassium channel, inwardly rectifying subfamily J, member 16 | 0.00664545 |
| MYO1B | myosin IB | 0.00663915 |
| L1CAM | L1 cell adhesion molecule | 0.00663784 |
| CX3CR1 | chemokine (C-X3-C motif) receptor 1 | 0.00663734 |
| PLLP | plasmolipin | 0.00661765 |
| LRP4 | low density lipoprotein receptor-related protein 4 | 0.00661007 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | 0.0066064 |
| COL2A1 | collagen, type II, alpha 1 | 0.00660637 |
| GREB1 | growth regulation by estrogen in breast cancer 1 | 0.00660306 |
| CHEK1 | checkpoint kinase 1 | 0.00660203 |
| PEG10 | paternally expressed 10 | 0.00659898 |
| CX3CL1 | chemokine (C-X3-C motif) ligand 1 | 0.00659235 |
| SMARCA1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 | 0.00658353 |
| MFSD10 | major facilitator superfamily domain containing 10 | 0.00657952 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.00657264 |
| ZNF721 | zinc finger protein 721 | 0.00655937 |
| VDAC2 | voltage-dependent anion channel 2 | 0.00654526 |
| SH3BP5 | SH3-domain binding protein 5 (BTK-associated) | 0.00654391 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.00652059 |
| MARF1 | meiosis regulator and mRNA stability factor 1 | 0.00651333 |
| CADM1 | cell adhesion molecule 1 | 0.00650599 |
| NOLC1 | nucleolar and coiled-body phosphoprotein 1 | 0.00650366 |
| NSG1 | neuron specific gene family member 1 | 0.0064425 |
| SH3GL2 | SH3-domain GRB2-like 2 | 0.00641521 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | 0.00638526 |
| OSBPL9 | oxysterol binding protein-like 9 | 0.00634815 |
| HELLS | helicase, lymphoid-specific | 0.00634119 |
| KARS1 | lysyl-tRNA synthetase 1 | 0.00633824 |
| DNTT | DNA nucleotidylexotransferase | 0.00632491 |
| GANAB | glucosidase, alpha; neutral AB | 0.00631589 |
| PPARGC1A | peroxisome proliferator-activated receptor gamma, coactivator 1 alpha | 0.00629066 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.00628638 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.00625991 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.00625761 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.00625291 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.00622757 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.00622619 |
| ARID4A | AT rich interactive domain 4A (RBP1-like) | 0.00622332 |
| MSLN | mesothelin | 0.00622097 |
| FGB | fibrinogen beta chain | 0.00622087 |
| MSX1 | msh homeobox 1 | 0.00621824 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.00620061 |
| MYO1C | myosin IC | 0.00619648 |
| PHIP | pleckstrin homology domain interacting protein | 0.00619111 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | 0.00617535 |
| OPHN1 | oligophrenin 1 | 0.00616625 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.00615526 |
| KRT5 | keratin 5, type II | 0.00615297 |
| ATP1A1 | ATPase, Na+/K+ transporting, alpha 1 polypeptide | 0.00614235 |
| RASSF2 | Ras association (RalGDS/AF-6) domain family member 2 | 0.00612475 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | 0.00608984 |
| PCDH9 | protocadherin 9 | 0.00608802 |
| CALCA | calcitonin-related polypeptide alpha | 0.00606737 |
| DSG1 | desmoglein 1 | 0.00606651 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.00604986 |
| EMP2 | epithelial membrane protein 2 | 0.00604724 |
| ATF4 | activating transcription factor 4 | 0.0060437 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 | 0.0060149 |
| MT1G | metallothionein 1G | 0.00601479 |
| NOTCH2NL | notch 2 N-terminal like | 0.00601157 |
| MBD1 | methyl-CpG binding domain protein 1 | 0.0059988 |
| MFAP3L | microfibrillar-associated protein 3-like | 0.00599833 |
| BMP2 | bone morphogenetic protein 2 | 0.00598754 |
| OLFML3 | olfactomedin-like 3 | 0.00598698 |
| EIF6 | eukaryotic translation initiation factor 6 | 0.00598468 |
| MFSD12 | major facilitator superfamily domain containing 12 | 0.00596642 |
| GPC4 | glypican 4 | 0.00596351 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.00594629 |
| ABCA12 | ATP-binding cassette, sub-family A (ABC1), member 12 | 0.00594431 |
| COL6A1 | collagen, type VI, alpha 1 | 0.00592959 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.00592535 |
| HMBOX1 | homeobox containing 1 | 0.00591258 |
| LMO2 | LIM domain only 2 (rhombotin-like 1) | 0.00590057 |
| NCALD | neurocalcin delta | 0.0058947 |
| FAM222B | family with sequence similarity 222, member B | 0.00585433 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.00582745 |
| NUP93 | nucleoporin 93kDa | 0.0058114 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.00580546 |
| MAOB | monoamine oxidase B | 0.0057956 |
| TPBG | trophoblast glycoprotein | 0.00577643 |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 | 0.0057682 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.00576013 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.00575938 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) | 0.00574688 |
| ANK2 | ankyrin 2, neuronal | 0.00574479 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.00573856 |
| DDX42 | DEAD (Asp-Glu-Ala-Asp) box helicase 42 | 0.00573668 |
| SCGB1A1 | secretoglobin, family 1A, member 1 (uteroglobin) | 0.00573528 |
| LOR | loricrin | 0.00572513 |
| ANXA3 | annexin A3 | 0.00572327 |
| TMEM45A | transmembrane protein 45A | 0.00572308 |
| SEC14L1 | SEC14-like 1 (S. cerevisiae) | 0.00570761 |
| VCL | vinculin | 0.00570728 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | 0.00569512 |
| FEZ1 | fasciculation and elongation protein zeta 1 (zygin I) | 0.00568244 |
| ALB | albumin | 0.00567308 |
| SPRR2B | small proline-rich protein 2B | 0.00567163 |
| RRAS2 | related RAS viral (r-ras) oncogene homolog 2 | 0.00566266 |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') | 0.00563982 |
| STXBP2 | syntaxin binding protein 2 | 0.00560911 |
| SERPINB4 | serpin peptidase inhibitor, clade B (ovalbumin), member 4 | 0.00557919 |
| KCNK12 | potassium channel, two pore domain subfamily K, member 12 | 0.00557595 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.00555616 |
| GAS7 | growth arrest-specific 7 | 0.0055505 |
| SERINC3 | serine incorporator 3 | 0.0055492 |
| GLDC | glycine dehydrogenase (decarboxylating) | 0.00554175 |
| LRIG1 | leucine-rich repeats and immunoglobulin-like domains 1 | 0.00553352 |
| DDB2 | damage-specific DNA binding protein 2, 48kDa | 0.0055157 |
| CPS1 | carbamoyl-phosphate synthase 1, mitochondrial | 0.00550011 |
| SCEL | sciellin | 0.00548864 |
| FAIM | Fas apoptotic inhibitory molecule | 0.00548487 |
| C9 | complement component 9 | 0.00548107 |
| PABPC3 | poly(A) binding protein, cytoplasmic 3 | 0.00547608 |
| TUBB6 | tubulin, beta 6 class V | 0.00546841 |
| SLC35E3 | solute carrier family 35, member E3 | 0.00546505 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | 0.00543704 |
| RPN2 | ribophorin II | 0.00543487 |
| PER1 | period circadian clock 1 | 0.00542937 |
| HOMER2 | homer scaffolding protein 2 | 0.0054287 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 | 0.00542572 |
| BEX1 | brain expressed, X-linked 1 | 0.00541415 |
| CDV3 | CDV3 homolog (mouse) | 0.00540519 |
| ANXA5 | annexin A5 | 0.00540244 |
| PRRC2C | proline-rich coiled-coil 2C | 0.00538951 |
| PLIN2 | perilipin 2 | 0.00537802 |
| ANKRD11 | ankyrin repeat domain 11 | 0.00537532 |
| MOXD1 | monooxygenase, DBH-like 1 | 0.00536918 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.00536304 |
| UGT2B28 | UDP glucuronosyltransferase 2 family, polypeptide B28 | 0.00535993 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.00534478 |
| USP6NL | USP6 N-terminal like | 0.00533887 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | 0.00533092 |
| CRCT1 | cysteine-rich C-terminal 1 | 0.00533012 |
| MALT1 | MALT1 paracaspase | 0.00531802 |
| CYB5R2 | cytochrome b5 reductase 2 | 0.00531141 |
| ZNF638 | zinc finger protein 638 | 0.00530445 |
| CNBP | CCHC-type zinc finger, nucleic acid binding protein | 0.00528305 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | 0.00527036 |
| STK10 | serine/threonine kinase 10 | 0.00526739 |
| TUBB2A | tubulin, beta 2A class IIa | 0.00526506 |
| DKK4 | dickkopf WNT signaling pathway inhibitor 4 | 0.00524691 |
| MPDZ | multiple PDZ domain protein | 0.00524199 |
| PEBP1 | phosphatidylethanolamine binding protein 1 | 0.00523365 |
| RBM34 | RNA binding motif protein 34 | 0.00523102 |
| FGL1 | fibrinogen-like 1 | 0.00522488 |
| FGA | fibrinogen alpha chain | 0.00521587 |
| Symbol | Name | Standardized Value |
|---|---|---|
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -0.0162039 |
| MAP7 | microtubule-associated protein 7 | -0.0146876 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0140799 |
| LTF | lactotransferrin | -0.0139958 |
| TFF1 | trefoil factor 1 | -0.0138044 |
| SEPP1 | selenoprotein P, plasma, 1 | -0.0125911 |
| TPSAB1 | tryptase alpha/beta 1 | -0.0125871 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | -0.0124039 |
| TFF3 | trefoil factor 3 (intestinal) | -0.0122694 |
| MMP9 | matrix metallopeptidase 9 | -0.0121034 |
| TNNT1 | troponin T type 1 (skeletal, slow) | -0.011369 |
| MMP12 | matrix metallopeptidase 12 | -0.0111718 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | -0.0108156 |
| ADAMDEC1 | ADAM-like, decysin 1 | -0.0106876 |
| KRT20 | keratin 20, type I | -0.0103844 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | -0.0103784 |
| PMP22 | peripheral myelin protein 22 | -0.0103597 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) | -0.0102211 |
| DCK | deoxycytidine kinase | -0.010197 |
| MMP1 | matrix metallopeptidase 1 | -0.0101723 |
| KRT19 | keratin 19, type I | -0.0101331 |
| GNA11 | guanine nucleotide binding protein (G protein), alpha 11 (Gq class) | -0.0100582 |
| C1QA | complement component 1, q subcomponent, A chain | -0.00980845 |
| H1-2 | H1.2 linker histone, cluster member | -0.00979587 |
| HEPH | hephaestin | -0.00976154 |
| LXN | latexin | -0.00968096 |
| OLFM4 | olfactomedin 4 | -0.00956897 |
| VCAM1 | vascular cell adhesion molecule 1 | -0.00951462 |
| KDM5D | lysine (K)-specific demethylase 5D | -0.00951107 |
| MAD2L1 | MAD2 mitotic arrest deficient-like 1 (yeast) | -0.00921884 |
| NDUFA4L2 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2 | -0.00917301 |
| GPX2 | glutathione peroxidase 2 | -0.00911906 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.00911682 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 | -0.00911098 |
| CLCA1 | chloride channel accessory 1 | -0.00909085 |
| DPM3 | dolichyl-phosphate mannosyltransferase polypeptide 3 | -0.0090812 |
| DIPK1A | divergent protein kinase domain 1A | -0.00896448 |
| EVI2A | ecotropic viral integration site 2A | -0.00885492 |
| C1QB | complement component 1, q subcomponent, B chain | -0.0088487 |
| THAP12 | THAP domain containing 12 | -0.00884084 |
| UGT2B17 | UDP glucuronosyltransferase 2 family, polypeptide B17 | -0.00866096 |
| NID2 | nidogen 2 (osteonidogen) | -0.00861068 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming | -0.00856652 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | -0.00854093 |
| LYZ | lysozyme | -0.00854004 |
| SLC44A4 | solute carrier family 44, member 4 | -0.00853716 |
| LGALS2 | lectin, galactoside-binding, soluble, 2 | -0.00851957 |
| AKR7A2 | aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) | -0.0084978 |
| RTN2 | reticulon 2 | -0.00848261 |
| AKR1C3 | aldo-keto reductase family 1, member C3 | -0.00843968 |
| GNG10 | guanine nucleotide binding protein (G protein), gamma 10 | -0.00839549 |
| GALNT1 | polypeptide N-acetylgalactosaminyltransferase 1 | -0.00838937 |
| MPC2 | mitochondrial pyruvate carrier 2 | -0.00837335 |
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide | -0.00831202 |
| FUCA1 | fucosidase, alpha-L- 1, tissue | -0.00830656 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) | -0.00830267 |
| CTSH | cathepsin H | -0.00825141 |
| SPINK4 | serine peptidase inhibitor, Kazal type 4 | -0.00823734 |
| ENC1 | ectodermal-neural cortex 1 (with BTB domain) | -0.00822827 |
| TOX3 | TOX high mobility group box family member 3 | -0.00821323 |
| CEL | carboxyl ester lipase | -0.00805155 |
| CPA3 | carboxypeptidase A3 (mast cell) | -0.0079918 |
| TXLNA | taxilin alpha | -0.00799141 |
| APOBEC3G | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G | -0.00799053 |
| GRAMD4 | GRAM domain containing 4 | -0.0079592 |
| GALNT3 | polypeptide N-acetylgalactosaminyltransferase 3 | -0.00792567 |
| ALDH3A2 | aldehyde dehydrogenase 3 family, member A2 | -0.00790111 |
| PHACTR2 | phosphatase and actin regulator 2 | -0.00789613 |
| CA12 | carbonic anhydrase XII | -0.00788133 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.00786009 |
| NPM3 | nucleophosmin/nucleoplasmin 3 | -0.00783635 |
| DUSP5 | dual specificity phosphatase 5 | -0.00779033 |
| SUB1 | SUB1 homolog (S. cerevisiae) | -0.00775397 |
| RPA3 | replication protein A3, 14kDa | -0.00775161 |
| TRIB2 | tribbles pseudokinase 2 | -0.00769608 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | -0.00767243 |
| AREG | amphiregulin | -0.00766334 |
| MS4A6A | membrane-spanning 4-domains, subfamily A, member 6A | -0.0076501 |
| TMEM14A | transmembrane protein 14A | -0.00763453 |
| RNF19B | ring finger protein 19B | -0.00759855 |
| CHST2 | carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 | -0.00757064 |
| RAMP1 | receptor (G protein-coupled) activity modifying protein 1 | -0.00757034 |
| JCHAIN | joining chain of multimeric IgA and IgM | -0.00755338 |
| S100A8 | S100 calcium binding protein A8 | -0.00753455 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | -0.00751608 |
| AOC1 | amine oxidase, copper containing 1 | -0.00747804 |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 | -0.00742507 |
| PLAU | plasminogen activator, urokinase | -0.00741152 |
| SFRP4 | secreted frizzled-related protein 4 | -0.00736135 |
| MS4A4A | membrane-spanning 4-domains, subfamily A, member 4A | -0.00732085 |
| HBB | hemoglobin, beta | -0.00728182 |
| ADORA2B | adenosine A2b receptor | -0.0072809 |
| HNMT | histamine N-methyltransferase | -0.00715185 |
| CD14 | CD14 molecule | -0.00714845 |
| GSAP | gamma-secretase activating protein | -0.00713065 |
| PLN | phospholamban | -0.00708684 |
| APOBEC3B | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B | -0.00706737 |
| DCXR | dicarbonyl/L-xylulose reductase | -0.00706735 |
| HCLS1 | hematopoietic cell-specific Lyn substrate 1 | -0.00706237 |
| HOXC6 | homeobox C6 | -0.00703375 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.00703365 |
| ZBTB18 | zinc finger and BTB domain containing 18 | -0.00702436 |
| TMEM126B | transmembrane protein 126B | -0.00701927 |
| PTGER4 | prostaglandin E receptor 4 (subtype EP4) | -0.00699919 |
| SMPDL3A | sphingomyelin phosphodiesterase, acid-like 3A | -0.00699739 |
| HPGDS | hematopoietic prostaglandin D synthase | -0.00697838 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | -0.00696816 |
| JAG1 | jagged 1 | -0.00696592 |
| RAB40B | RAB40B, member RAS oncogene family | -0.00695903 |
| MUC2 | mucin 2, oligomeric mucus/gel-forming | -0.006942 |
| MARCKSL1 | MARCKS-like 1 | -0.00692656 |
| REG1A | regenerating islet-derived 1 alpha | -0.00690836 |
| PLEKHF2 | pleckstrin homology domain containing, family F (with FYVE domain) member 2 | -0.00689319 |
| RFK | riboflavin kinase | -0.00688087 |
| COL10A1 | collagen, type X, alpha 1 | -0.00687261 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | -0.00685735 |
| ASPN | asporin | -0.00684795 |
| CSF2RB | colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) | -0.0067925 |
| PFDN4 | prefoldin subunit 4 | -0.00677607 |
| CD320 | CD320 molecule | -0.00675041 |
| PCP4 | Purkinje cell protein 4 | -0.00675014 |
| TSPAN6 | tetraspanin 6 | -0.00674969 |
| HMGN4 | high mobility group nucleosomal binding domain 4 | -0.00673588 |
| TNFRSF14 | tumor necrosis factor receptor superfamily, member 14 | -0.00672713 |
| HBD | hemoglobin, delta | -0.00671554 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 | -0.00668878 |
| AK1 | adenylate kinase 1 | -0.00668021 |
| RBX1 | ring-box 1, E3 ubiquitin protein ligase | -0.00667436 |
| TMEM14B | transmembrane protein 14B | -0.00666954 |
| AP5M1 | adaptor-related protein complex 5, mu 1 subunit | -0.00666852 |
| SRGN | serglycin | -0.00666791 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.00666557 |
| AKAP7 | A kinase (PRKA) anchor protein 7 | -0.00664488 |
| LGALS4 | lectin, galactoside-binding, soluble, 4 | -0.00664428 |
| FCER1G | Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide | -0.0066408 |
| DBF4 | DBF4 zinc finger | -0.00663726 |
| IL18 | interleukin 18 | -0.00663124 |
| BAMBI | BMP and activin membrane-bound inhibitor | -0.00661565 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) | -0.00661382 |
| COMP | cartilage oligomeric matrix protein | -0.00661054 |
| TSPAN1 | tetraspanin 1 | -0.00660194 |
| PRKACB | protein kinase, cAMP-dependent, catalytic, beta | -0.00657746 |
| FAM3C | family with sequence similarity 3, member C | -0.00656664 |
| CD48 | CD48 molecule | -0.00655676 |
| PLA2G7 | phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) | -0.00653767 |
| DAB2 | Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) | -0.00652896 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.00652838 |
| ITGB3BP | integrin beta 3 binding protein (beta3-endonexin) | -0.00649522 |
| CHKB | choline kinase beta | -0.00649064 |
| ITGAE | integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) | -0.00648698 |
| CCND1 | cyclin D1 | -0.00647975 |
| CCL19 | chemokine (C-C motif) ligand 19 | -0.00647655 |
| ECI2 | enoyl-CoA delta isomerase 2 | -0.00647456 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | -0.00646705 |
| ANPEP | alanyl (membrane) aminopeptidase | -0.00643501 |
| SLC37A4 | solute carrier family 37 (glucose-6-phosphate transporter), member 4 | -0.00640681 |
| QPCT | glutaminyl-peptide cyclotransferase | -0.00639414 |
| TMEM106B | transmembrane protein 106B | -0.00638171 |
| COMMD8 | COMM domain containing 8 | -0.00637099 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.00636988 |
| GJA1 | gap junction protein, alpha 1, 43kDa | -0.00636836 |
| BTK | Bruton agammaglobulinemia tyrosine kinase | -0.00636764 |
| TFEC | transcription factor EC | -0.00636566 |
| SDC2 | syndecan 2 | -0.00636492 |
| DUOX2 | dual oxidase 2 | -0.00636173 |
| GALC | galactosylceramidase | -0.00632734 |
| SOCS1 | suppressor of cytokine signaling 1 | -0.00632132 |
| ACTN1 | actinin, alpha 1 | -0.00632042 |
| EMP3 | epithelial membrane protein 3 | -0.00630007 |
| PHYH | phytanoyl-CoA 2-hydroxylase | -0.00629201 |
| PDLIM3 | PDZ and LIM domain 3 | -0.00629157 |
| GRIA2 | glutamate receptor, ionotropic, AMPA 2 | -0.00628954 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | -0.00628596 |
| HDDC2 | HD domain containing 2 | -0.00627952 |
| CST7 | cystatin F (leukocystatin) | -0.0062738 |
| CD163 | CD163 molecule | -0.00626421 |
| CILP | cartilage intermediate layer protein, nucleotide pyrophosphohydrolase | -0.00625074 |
| PSMB3 | proteasome (prosome, macropain) subunit, beta type, 3 | -0.00623701 |
| GPX3 | glutathione peroxidase 3 | -0.00623425 |
| FCGR2B | Fc fragment of IgG, low affinity IIb, receptor (CD32) | -0.00623276 |
| SAMSN1 | SAM domain, SH3 domain and nuclear localization signals 1 | -0.00621366 |
| PTGES2 | prostaglandin E synthase 2 | -0.0062096 |
| CYFIP2 | cytoplasmic FMR1 interacting protein 2 | -0.0062059 |
| GET1 | guided entry of tail-anchored proteins factor 1 | -0.00618891 |
| LY96 | lymphocyte antigen 96 | -0.00618652 |
| MRPL12 | mitochondrial ribosomal protein L12 | -0.00616033 |
| PRR5 | proline rich 5 (renal) | -0.0061514 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.00614045 |
| NOTCH1 | notch 1 | -0.00612398 |
| BAD | BCL2-associated agonist of cell death | -0.00611237 |
| IGSF6 | immunoglobulin superfamily, member 6 | -0.00611041 |
| TWF1 | twinfilin actin binding protein 1 | -0.00608919 |
| CCL8 | chemokine (C-C motif) ligand 8 | -0.00608008 |
| LSM7 | LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -0.00607471 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | -0.00606801 |
| FOLR2 | folate receptor 2 (fetal) | -0.00605425 |
| MEST | mesoderm specific transcript | -0.00604111 |
| NIPSNAP2 | nipsnap homolog 2 | -0.00602955 |
| DEPTOR | DEP domain containing MTOR-interacting protein | -0.00599607 |
| METRN | meteorin, glial cell differentiation regulator | -0.00597636 |
| HIST3H2A | histone cluster 3, H2a | -0.00596514 |
| CENPM | centromere protein M | -0.00595865 |
| CDK1 | cyclin-dependent kinase 1 | -0.00593663 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | -0.00593005 |
| MYB | v-myb avian myeloblastosis viral oncogene homolog | -0.00591271 |
| MLF1 | myeloid leukemia factor 1 | -0.00589673 |
| EGFL7 | EGF-like-domain, multiple 7 | -0.00589508 |
| PSMD3 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 | -0.00588229 |
| SLC46A3 | solute carrier family 46, member 3 | -0.00586769 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.00586407 |
| FABP6 | fatty acid binding protein 6, ileal | -0.0058625 |
| TGFB1I1 | transforming growth factor beta 1 induced transcript 1 | -0.00586216 |
| MCOLN1 | mucolipin 1 | -0.0058573 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 | -0.00585674 |
| ACSL5 | acyl-CoA synthetase long-chain family member 5 | -0.00584728 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | -0.00584398 |
| CCR2 | chemokine (C-C motif) receptor 2 | -0.00584344 |
| SLC27A2 | solute carrier family 27 (fatty acid transporter), member 2 | -0.00583537 |
| PPP2R3C | protein phosphatase 2, regulatory subunit B'', gamma | -0.00582898 |
| PHLDA2 | pleckstrin homology-like domain, family A, member 2 | -0.00579677 |
| CENPX | centromere protein X | -0.00579667 |
| PSTPIP2 | proline-serine-threonine phosphatase interacting protein 2 | -0.00578521 |
| HOPX | HOP homeobox | -0.00577705 |
| CLEC10A | C-type lectin domain family 10, member A | -0.00576487 |
| ANKRD10 | ankyrin repeat domain 10 | -0.00576337 |
| CREG1 | cellular repressor of E1A-stimulated genes 1 | -0.00575927 |
| TMEM38B | transmembrane protein 38B | -0.00575675 |
| EVA1B | eva-1 homolog B (C. elegans) | -0.00574476 |
| TMEM176B | transmembrane protein 176B | -0.00573785 |
| MYCL | v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog | -0.00572417 |
| HES1 | hes family bHLH transcription factor 1 | -0.00570157 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | -0.00569898 |
| SLC9A3R1 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 | -0.00569723 |
| IL7 | interleukin 7 | -0.00569374 |
| MFAP5 | microfibrillar associated protein 5 | -0.00568747 |
| DACH1 | dachshund family transcription factor 1 | -0.00567712 |
| MTA1 | metastasis associated 1 | -0.00565142 |
| GSTO1 | glutathione S-transferase omega 1 | -0.00564789 |
| GZMA | granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) | -0.00563398 |
| ZSCAN18 | zinc finger and SCAN domain containing 18 | -0.00562628 |
| SLC25A11 | solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11 | -0.00562504 |
| EML3 | echinoderm microtubule associated protein like 3 | -0.0056215 |
| NDUFB7 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa | -0.00561915 |
| CLDN4 | claudin 4 | -0.0056179 |
| TAGLN | transgelin | -0.00560328 |
| SH3BGRL | SH3 domain binding glutamate-rich protein like | -0.00559488 |
| UTP18 | UTP18 small subunit (SSU) processome component homolog (yeast) | -0.00559421 |
| EFNB2 | ephrin-B2 | -0.00558615 |
