CAL-120 Gene Set

Dataset GDSC Cell Line Gene Expression Profiles
Category transcriptomics
Type cell line
Description disease: adenocarcinoma, breast (Cell Line Ontology, CLO_0002179)
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Genes

316 genes with high or low expression in CAL-120 relative to other cell lines from the GDSC Cell Line Gene Expression Profiles dataset.

high expression

Symbol Name Standardized Value
ARL1 ADP-ribosylation factor-like 1 3.60177
IRF3 interferon regulatory factor 3 3.60177
GINS4 GINS complex subunit 4 (Sld5 homolog) 3.60177
EIF6 eukaryotic translation initiation factor 6 3.13786
CNOT2 CCR4-NOT transcription complex, subunit 2 3.12489
SFRP1 secreted frizzled-related protein 1 3.04437
PSG2 pregnancy specific beta-1-glycoprotein 2 2.9948
PRMT1 protein arginine methyltransferase 1 2.98329
XPO6 exportin 6 2.92529
RRAS related RAS viral (r-ras) oncogene homolog 2.91088
TBC1D10B TBC1 domain family, member 10B 2.85178
PSG9 pregnancy specific beta-1-glycoprotein 9 2.8277
VDAC3 voltage-dependent anion channel 3 2.74304
NOSIP nitric oxide synthase interacting protein 2.69121
MAP2K2 mitogen-activated protein kinase kinase 2 2.67395
PIP4K2C phosphatidylinositol-5-phosphate 4-kinase, type II, gamma 2.56594
OXTR oxytocin receptor 2.55562
CCT2 chaperonin containing TCP1, subunit 2 (beta) 2.55513
FIBP fibroblast growth factor (acidic) intracellular binding protein 2.50953
ZNF580 zinc finger protein 580 2.49818
MAP4 microtubule-associated protein 4 2.45201
BRF2 BRF2, RNA polymerase III transcription initiation factor 50 kDa subunit 2.43679
TSPAN31 tetraspanin 31 2.37109
ERLIN2 ER lipid raft associated 2 2.37009
DCTN2 dynactin 2 (p50) 2.36641
BTN2A3P butyrophilin, subfamily 2, member A3, pseudogene 2.35705
LSM1 LSM1, U6 small nuclear RNA associated 2.35428
MMP24 matrix metallopeptidase 24 (membrane-inserted) 2.35298
SAC3D1 SAC3 domain containing 1 2.35009
TMF1 TATA element modulatory factor 1 2.3484
PFDN1 prefoldin subunit 1 2.32522
METTL1 methyltransferase like 1 2.31011
GFRA4 GDNF family receptor alpha 4 2.25557
PSG6 pregnancy specific beta-1-glycoprotein 6 2.25024
TCTA T-cell leukemia translocation altered 2.24917
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1 2.24465
DNAH7 dynein, axonemal, heavy chain 7 2.23027
DAP death-associated protein 2.20225
PSG1 pregnancy specific beta-1-glycoprotein 1 2.18723
OR11A1 olfactory receptor, family 11, subfamily A, member 1 2.18553
PSG5 pregnancy specific beta-1-glycoprotein 5 2.18483
DCTPP1 dCTP pyrophosphatase 1 2.1659
PIH1D1 PIH1 domain containing 1 2.15266
CTDSP2 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2 2.13759
FNTA farnesyltransferase, CAAX box, alpha 2.13655
OS9 osteosarcoma amplified 9, endoplasmic reticulum lectin 2.10609
LETM1 leucine zipper-EF-hand containing transmembrane protein 1 2.09082
IP6K1 inositol hexakisphosphate kinase 1 2.07898
EXOC7 exocyst complex component 7 2.06664
TDRD12 tudor domain containing 12 2.0656
YEATS4 YEATS domain containing 4 2.06334
CDK4 cyclin-dependent kinase 4 2.06214
DDHD2 DDHD domain containing 2 2.04552
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha 2.0429
ARL2 ADP-ribosylation factor-like 2 2.03658
PTPRR protein tyrosine phosphatase, receptor type, R 2.0306
ITGBL1 integrin, beta-like 1 (with EGF-like repeat domains) 2.02926
CPA4 carboxypeptidase A4 2.00312
PSG3 pregnancy specific beta-1-glycoprotein 3 1.9914
FAM127A family with sequence similarity 127, member A 1.98974
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta 1.98083
TSFM Ts translation elongation factor, mitochondrial 1.97199
CHMP6 charged multivesicular body protein 6 1.95079
CCDC85B coiled-coil domain containing 85B 1.94773
PSG7 pregnancy specific beta-1-glycoprotein 7 (gene/pseudogene) 1.93746
TBCD tubulin folding cofactor D 1.93653
FGFR1 fibroblast growth factor receptor 1 1.92633
PTH parathyroid hormone 1.9209
SLC18A3 solute carrier family 18 (vesicular acetylcholine transporter), member 3 1.90054
ABI3BP ABI family, member 3 (NESH) binding protein 1.87826
BIRC5 baculoviral IAP repeat containing 5 1.87139
POLR2L polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa 1.86856
ADD1 adducin 1 (alpha) 1.85849
PROSC proline synthetase co-transcribed homolog (bacterial) 1.85813
NRSN2 neurensin 2 1.85477
TAF10 TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa 1.85049
NPLOC4 nuclear protein localization 4 homolog (S. cerevisiae) 1.8377
PCYT2 phosphate cytidylyltransferase 2, ethanolamine 1.8213
CDH18 cadherin 18, type 2 1.82059
RASSF1 Ras association (RalGDS/AF-6) domain family member 1 1.81909
TARBP2 TAR (HIV-1) RNA binding protein 2 1.80341
NCLN nicalin 1.7927
KCTD2 potassium channel tetramerization domain containing 2 1.79142
PLIN3 perilipin 3 1.78681
ANK1 ankyrin 1, erythrocytic 1.78273
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 1.78078
PSG4 pregnancy specific beta-1-glycoprotein 4 1.77566
U2AF2 U2 small nuclear RNA auxiliary factor 2 1.77472
MBOAT7 membrane bound O-acyltransferase domain containing 7 1.772
EDDM3A epididymal protein 3A 1.76789
CAPNS1 calpain, small subunit 1 1.76339
GPS1 G protein pathway suppressor 1 1.75504
HGS hepatocyte growth factor-regulated tyrosine kinase substrate 1.74863
CDH10 cadherin 10, type 2 (T2-cadherin) 1.74789
WNT5B wingless-type MMTV integration site family, member 5B 1.74587
ZNF304 zinc finger protein 304 1.73854
USP14 ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) 1.73139
METTL21B methyltransferase like 21B 1.73008
NME6 NME/NM23 nucleoside diphosphate kinase 6 1.72142
CD2BP2 CD2 (cytoplasmic tail) binding protein 2 1.7186
AQP5 aquaporin 5 1.71735
ZNF835 zinc finger protein 835 1.71501
ZNF428 zinc finger protein 428 1.7108
FAM64A family with sequence similarity 64, member A 1.70987
UBE2M ubiquitin-conjugating enzyme E2M 1.69807
AP3M2 adaptor-related protein complex 3, mu 2 subunit 1.69753
ASAP1-IT1 ASAP1 intronic transcript 1 1.69503
ZNF365 zinc finger protein 365 1.69068
NPTX1 neuronal pentraxin I 1.68756
CCDC86 coiled-coil domain containing 86 1.68088
RNF40 ring finger protein 40, E3 ubiquitin protein ligase 1.68049
CDC20 cell division cycle 20 1.68026
APEH acylaminoacyl-peptide hydrolase 1.6652
ARL15 ADP-ribosylation factor-like 15 1.66472
CYB5R2 cytochrome b5 reductase 2 1.66278
ANGPTL7 angiopoietin-like 7 1.65992
CEP250 centrosomal protein 250kDa 1.65753
ACTC1 actin, alpha, cardiac muscle 1 1.65336
AIPL1 aryl hydrocarbon receptor interacting protein-like 1 1.65331
MS4A12 membrane-spanning 4-domains, subfamily A, member 12 1.64662
GATB glutamyl-tRNA(Gln) amidotransferase, subunit B 1.64576
TUSC2 tumor suppressor candidate 2 1.64194
NF2 neurofibromin 2 (merlin) 1.63342
CDCA3 cell division cycle associated 3 1.6332
POLB polymerase (DNA directed), beta 1.63183
TEX261 testis expressed 261 1.62888
NAPA N-ethylmaleimide-sensitive factor attachment protein, alpha 1.62778
AGTR1 angiotensin II receptor, type 1 1.62575
BCKDK branched chain ketoacid dehydrogenase kinase 1.62406
MOSPD1 motile sperm domain containing 1 1.62196
RGS7 regulator of G-protein signaling 7 1.61994
HIST1H4L histone cluster 1, H4l 1.61939
ZNF629 zinc finger protein 629 1.61164
HDLBP high density lipoprotein binding protein 1.61106
MICU1 mitochondrial calcium uptake 1 1.60985
FOXM1 forkhead box M1 1.60968
CYB561D2 cytochrome b561 family, member D2 1.60833
FZD2 frizzled class receptor 2 1.60648
MLF2 myeloid leukemia factor 2 1.60273
ACOT8 acyl-CoA thioesterase 8 1.59793
DIO2 deiodinase, iodothyronine, type II 1.59741
CHPT1 choline phosphotransferase 1 1.59614
CUTA cutA divalent cation tolerance homolog (E. coli) 1.59294
GPX1 glutathione peroxidase 1 1.58398
TIMM8B translocase of inner mitochondrial membrane 8 homolog B (yeast) 1.57726
SERPINB7 serpin peptidase inhibitor, clade B (ovalbumin), member 7 1.57501
HUNK hormonally up-regulated Neu-associated kinase 1.57385
NAT6 N-acetyltransferase 6 (GCN5-related) 1.57196
KLF8 Kruppel-like factor 8 1.56467
USP5 ubiquitin specific peptidase 5 (isopeptidase T) 1.56459
GATAD2A GATA zinc finger domain containing 2A 1.56318
RNF123 ring finger protein 123 1.55714
MRPL12 mitochondrial ribosomal protein L12 1.54997
MFSD10 major facilitator superfamily domain containing 10 1.54829
PDZD3 PDZ domain containing 3 1.5427
PPME1 protein phosphatase methylesterase 1 1.54142
VKORC1 vitamin K epoxide reductase complex, subunit 1 1.5398
PYCR1 pyrroline-5-carboxylate reductase 1 1.53542
FGF8 fibroblast growth factor 8 (androgen-induced) 1.53006
FEZ2 fasciculation and elongation protein zeta 2 (zygin II) 1.52942
TLE4 transducin-like enhancer of split 4 1.52917
ZNF688 zinc finger protein 688 1.52733
SLC16A7 solute carrier family 16 (monocarboxylate transporter), member 7 1.52541
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) 1.52178
SRM spermidine synthase 1.51935
PPP2R5B protein phosphatase 2, regulatory subunit B', beta 1.51271
LILRA5 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5 1.51001
PRPF31 pre-mRNA processing factor 31 1.50907
WDR62 WD repeat domain 62 1.50787
NIN ninein (GSK3B interacting protein) 1.50556
MGP matrix Gla protein 1.503
WISP2 WNT1 inducible signaling pathway protein 2 1.50202
BANF1 barrier to autointegration factor 1 1.50086
EBNA1BP2 EBNA1 binding protein 2 1.49934
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 1.497
TK1 thymidine kinase 1, soluble 1.49026
NUP85 nucleoporin 85kDa 1.48603
H2AFX H2A histone family, member X 1.4857
GMPPB GDP-mannose pyrophosphorylase B 1.48322
PKMYT1 protein kinase, membrane associated tyrosine/threonine 1 1.48181
TRIM58 tripartite motif containing 58 1.47871
SEC14L1 SEC14-like 1 (S. cerevisiae) 1.47558
CRYBB2 crystallin, beta B2 1.47414
PRR13 proline rich 13 1.47286
SLC27A5 solute carrier family 27 (fatty acid transporter), member 5 1.47172
TYRP1 tyrosinase-related protein 1 1.46433
DST dystonin 1.46131
SLC17A6 solute carrier family 17 (vesicular glutamate transporter), member 6 1.46082
DNAH2 dynein, axonemal, heavy chain 2 1.45546
LRTOMT leucine rich transmembrane and O-methyltransferase domain containing 1.45437
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase 1.45374
SEC24C SEC24 family member C 1.45298
GJA3 gap junction protein, alpha 3, 46kDa 1.45101
ISOC2 isochorismatase domain containing 2 1.4484
ADAMTS6 ADAM metallopeptidase with thrombospondin type 1 motif, 6 1.447
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 1.44321
GOLGA7 golgin A7 1.44129
FLT3LG fms-related tyrosine kinase 3 ligand 1.44003
MMP20 matrix metallopeptidase 20 1.43561
GNG5 guanine nucleotide binding protein (G protein), gamma 5 1.43287
ZSWIM8 zinc finger, SWIM-type containing 8 1.42703
KRT76 keratin 76, type II 1.42646
CELA3B chymotrypsin-like elastase family, member 3B 1.42609
COQ2 coenzyme Q2 4-hydroxybenzoate polyprenyltransferase 1.42195
PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha 1.4199
PSRC1 proline/serine-rich coiled-coil 1 1.41916

low expression

Symbol Name Standardized Value
SUPT7L suppressor of Ty 7 (S. cerevisiae)-like -3.51208
GSR glutathione reductase -3.44493
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2 -3.20481
HIP1 huntingtin interacting protein 1 -2.61888
ICE2 interactor of little elongation complex ELL subunit 2 -2.52035
CCDC28A coiled-coil domain containing 28A -2.49917
CREBBP CREB binding protein -2.49013
PALB2 partner and localizer of BRCA2 -2.48732
RTF1 Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) -2.4525
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila) -2.40638
THUMPD1 THUMP domain containing 1 -2.37357
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4 -2.33495
NR2C2 nuclear receptor subfamily 2, group C, member 2 -2.22039
MGC12488 -2.1502
NMD3 NMD3 ribosome export adaptor -2.13334
FRAT2 frequently rearranged in advanced T-cell lymphomas 2 -2.10471
ZC3H11A zinc finger CCCH-type containing 11A -2.10325
MAP3K7 mitogen-activated protein kinase kinase kinase 7 -2.09435
VPS41 vacuolar protein sorting 41 homolog (S. cerevisiae) -2.09078
BTG3 BTG family, member 3 -2.04812
KCTD12 potassium channel tetramerization domain containing 12 -2.04064
GSE1 Gse1 coiled-coil protein -2.03868
LARGE like-glycosyltransferase -2.03342
LMBRD1 LMBR1 domain containing 1 -2.02405
RHOT1 ras homolog family member T1 -2.01291
LIAS lipoic acid synthetase -1.98262
SDF2 stromal cell-derived factor 2 -1.9681
DCLRE1A DNA cross-link repair 1A -1.96702
MAP3K2 mitogen-activated protein kinase kinase kinase 2 -1.95692
GSPT2 G1 to S phase transition 2 -1.95009
B4GALT3 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3 -1.93228
SNRK SNF related kinase -1.90968
NHLRC2 NHL repeat containing 2 -1.87597
SF3B1 splicing factor 3b, subunit 1, 155kDa -1.87378
ZBED4 zinc finger, BED-type containing 4 -1.86196
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal) -1.85192
PUM1 pumilio RNA-binding family member 1 -1.84714
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1 -1.8362
CORO2B coronin, actin binding protein, 2B -1.81706
ARID4A AT rich interactive domain 4A (RBP1-like) -1.81667
ZSCAN32 zinc finger and SCAN domain containing 32 -1.8067
MRPS18C mitochondrial ribosomal protein S18C -1.7904
ZNF318 zinc finger protein 318 -1.78504
SIRAL2 SIR2 antiphage like 2 -1.78051
AUTS2 autism susceptibility candidate 2 -1.78041
ST13 suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) -1.77836
EIF1B eukaryotic translation initiation factor 1B -1.776
USP21 ubiquitin specific peptidase 21 -1.77565
CGGBP1 CGG triplet repeat binding protein 1 -1.76558
ZNF200 zinc finger protein 200 -1.76061
CDC73 cell division cycle 73 -1.76037
PDCD6IP programmed cell death 6 interacting protein -1.75934
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5 -1.75188
RASSF3 Ras association (RalGDS/AF-6) domain family member 3 -1.74888
STAT5B signal transducer and activator of transcription 5B -1.73553
REPS1 RALBP1 associated Eps domain containing 1 -1.7338
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17 -1.70025
COPS2 COP9 signalosome subunit 2 -1.67345
DKFZP586I1420 uncharacterized protein DKFZp586I1420 -1.65703
WBP4 WW domain binding protein 4 -1.65465
CLASP2 cytoplasmic linker associated protein 2 -1.65295
SEL1L sel-1 suppressor of lin-12-like (C. elegans) -1.64929
PARP16 poly (ADP-ribose) polymerase family, member 16 -1.64552
PELI1 pellino E3 ubiquitin protein ligase 1 -1.64281
BMP8B bone morphogenetic protein 8b -1.63804
CBLL1 Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase -1.63465
NPTN neuroplastin -1.63084
TUBGCP3 tubulin, gamma complex associated protein 3 -1.62978
KRIT1 KRIT1, ankyrin repeat containing -1.62941
KBTBD2 kelch repeat and BTB (POZ) domain containing 2 -1.6252
ZBTB11 zinc finger and BTB domain containing 11 -1.61916
TANK TRAF family member-associated NFKB activator -1.61295
KIAA0430 KIAA0430 -1.60601
TOP2B topoisomerase (DNA) II beta 180kDa -1.59739
UBE2E1 ubiquitin-conjugating enzyme E2E 1 -1.59495
AVL9 AVL9 homolog (S. cerevisiase) -1.59451
RNF115 ring finger protein 115 -1.58842
INVS inversin -1.58715
SPG11 spastic paraplegia 11 (autosomal recessive) -1.5785
UFL1 UFM1-specific ligase 1 -1.57815
EIF3A eukaryotic translation initiation factor 3, subunit A -1.56203
SS18L2 synovial sarcoma translocation gene on chromosome 18-like 2 -1.55506
CEP97 centrosomal protein 97kDa -1.55114
IPCEF1 interaction protein for cytohesin exchange factors 1 -1.54462
RPUSD2 RNA pseudouridylate synthase domain containing 2 -1.53765
SDCCAG8 serologically defined colon cancer antigen 8 -1.52899
TRMT13 tRNA methyltransferase 13 homolog (S. cerevisiae) -1.51845
ATXN7 ataxin 7 -1.51513
TM2D3 TM2 domain containing 3 -1.51187
DPY19L1P1 DPY19L1 pseudogene 1 -1.49833
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b -1.49562
RABGAP1L RAB GTPase activating protein 1-like -1.49047
C3AR1 complement component 3a receptor 1 -1.49041
GGTLC1 gamma-glutamyltransferase light chain 1 -1.49012
METAP2 methionyl aminopeptidase 2 -1.48685
TMEM168 transmembrane protein 168 -1.47387
DUSP12 dual specificity phosphatase 12 -1.47237
SSBP3 single stranded DNA binding protein 3 -1.47157
ZNF250 zinc finger protein 250 -1.47101
DMTF1 cyclin D binding myb-like transcription factor 1 -1.46739
EXOC4 exocyst complex component 4 -1.46333
JAK2 Janus kinase 2 -1.45908
SACM1L SAC1 suppressor of actin mutations 1-like (yeast) -1.45745
ATP11A ATPase, class VI, type 11A -1.43653
CCDC59 coiled-coil domain containing 59 -1.42945
ARNT aryl hydrocarbon receptor nuclear translocator -1.42735
RNF111 ring finger protein 111 -1.42094
YIPF4 Yip1 domain family, member 4 -1.42024
DAZAP2 DAZ associated protein 2 -1.42012
GGA2 golgi-associated, gamma adaptin ear containing, ARF binding protein 2 -1.41956