CAL-148 Gene Set

Dataset GDSC Cell Line Gene Expression Profiles
Category transcriptomics
Type cell line
Description disease: adenocarcinoma, breast (Cell Line Ontology, CLO_0002181)
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Genes

347 genes with high or low expression in CAL-148 relative to other cell lines from the GDSC Cell Line Gene Expression Profiles dataset.

high expression

Symbol Name Standardized Value
DEGS1 delta(4)-desaturase, sphingolipid 1 3.56971
OAZ3 ornithine decarboxylase antizyme 3 3.39752
PMS2P2 postmeiotic segregation increased 2 pseudogene 2 3.24707
ADAM15 ADAM metallopeptidase domain 15 3.09022
EFNA3 ephrin-A3 2.9813
CHST1 carbohydrate (keratan sulfate Gal-6) sulfotransferase 1 2.76928
ZNF117 zinc finger protein 117 2.72205
SRP9 signal recognition particle 9kDa 2.68402
FBXO28 F-box protein 28 2.64918
USP21 ubiquitin specific peptidase 21 2.53145
DTX2P1-UPK3BP1-PMS2P11 DTX2P1-UPK3BP1-PMS2P11 readthrough transcribed pseudogene 2.529
CYB5A cytochrome b5 type A (microsomal) 2.46464
KDM5B lysine (K)-specific demethylase 5B 2.37846
ZNF253 zinc finger protein 253 2.36408
AP4M1 adaptor-related protein complex 4, mu 1 subunit 2.36348
CNIH4 cornichon family AMPA receptor auxiliary protein 4 2.34125
SDCCAG8 serologically defined colon cancer antigen 8 2.33249
NVL nuclear VCP-like 2.32275
LCMT2 leucine carboxyl methyltransferase 2 2.30726
ZNF43 zinc finger protein 43 2.29365
TTC13 tetratricopeptide repeat domain 13 2.28821
SLBP stem-loop binding protein 2.21973
PIK3C2G phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma 2.19977
H3F3A H3 histone, family 3A 2.18757
DCTPP1 dCTP pyrophosphatase 1 2.14839
RBBP9 retinoblastoma binding protein 9 2.14494
PPP4C protein phosphatase 4, catalytic subunit 2.14037
CYP2A13 cytochrome P450, family 2, subfamily A, polypeptide 13 2.132
SELENBP1 selenium binding protein 1 2.10679
SETMAR SET domain and mariner transposase fusion gene 2.09834
FAM13A family with sequence similarity 13, member A 2.09143
MRPL24 mitochondrial ribosomal protein L24 2.09008
EFNA4 ephrin-A4 2.07809
SLC1A2 solute carrier family 1 (glial high affinity glutamate transporter), member 2 2.06549
NDUFAB1 NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8kDa 2.06436
CASD1 CAS1 domain containing 1 2.0574
ARID4B AT rich interactive domain 4B (RBP1-like) 2.04991
CSAD cysteine sulfinic acid decarboxylase 2.0499
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H) 2.04663
REEP1 receptor accessory protein 1 1.99792
CACNB3 calcium channel, voltage-dependent, beta 3 subunit 1.9873
FH fumarate hydratase 1.97908
DHX9 DEAH (Asp-Glu-Ala-His) box helicase 9 1.94485
TAF4 TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa 1.94202
NUPL2 nucleoporin like 2 1.91704
PPY pancreatic polypeptide 1.91323
SYNGR4 synaptogyrin 4 1.91311
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta) 1.9114
PCNA proliferating cell nuclear antigen 1.90186
HADH hydroxyacyl-CoA dehydrogenase 1.89674
ZNF93 zinc finger protein 93 1.89644
PPA2 pyrophosphatase (inorganic) 2 1.88652
ZNF143 zinc finger protein 143 1.88492
DNAJC17 DnaJ (Hsp40) homolog, subfamily C, member 17 1.88305
UBN1 ubinuclein 1 1.87019
CREBBP CREB binding protein 1.86627
AKAP1 A kinase (PRKA) anchor protein 1 1.84753
HNRNPF heterogeneous nuclear ribonucleoprotein F 1.84032
PHF20 PHD finger protein 20 1.83921
PEX7 peroxisomal biogenesis factor 7 1.83906
ADNP activity-dependent neuroprotector homeobox 1.83782
NUP133 nucleoporin 133kDa 1.83718
ADSS adenylosuccinate synthase 1.83341
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial 1.82596
POLI polymerase (DNA directed) iota 1.8191
HILPDA hypoxia inducible lipid droplet-associated 1.81099
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5 1.80243
PEX11A peroxisomal biogenesis factor 11 alpha 1.80037
FOXA1 forkhead box A1 1.79854
SOAT2 sterol O-acyltransferase 2 1.79148
ZSCAN16 zinc finger and SCAN domain containing 16 1.77435
CCL1 chemokine (C-C motif) ligand 1 1.76395
HEBP2 heme binding protein 2 1.76074
VAV3 vav 3 guanine nucleotide exchange factor 1.7593
HIST1H2AL histone cluster 1, H2al 1.75566
CCP110 centriolar coiled coil protein 110kDa 1.75197
PGK1 phosphoglycerate kinase 1 1.74702
LSM6 LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) 1.74496
ZNF747 zinc finger protein 747 1.74136
ZNF180 zinc finger protein 180 1.71656
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) 1.70851
GTF3C1 general transcription factor IIIC, polypeptide 1, alpha 220kDa 1.70597
SIGLEC15 sialic acid binding Ig-like lectin 15 1.70469
GGPS1 geranylgeranyl diphosphate synthase 1 1.70083
SLC25A16 solute carrier family 25 (mitochondrial carrier), member 16 1.70031
HOXB3 homeobox B3 1.69958
KCNA4 potassium channel, voltage gated shaker related subfamily A, member 4 1.69716
ERI2 ERI1 exoribonuclease family member 2 1.69556
SPATA7 spermatogenesis associated 7 1.68812
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) 1.68303
ZFYVE21 zinc finger, FYVE domain containing 21 1.68223
GNPAT glyceronephosphate O-acyltransferase 1.67945
SPIDR scaffolding protein involved in DNA repair 1.67763
PDE8B phosphodiesterase 8B 1.67383
DAP3 death associated protein 3 1.67169
SETBP1 SET binding protein 1 1.66947
OR10J1 olfactory receptor, family 10, subfamily J, member 1 1.66905
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae) 1.66429
TRPS1 trichorhinophalangeal syndrome I 1.66296
CDC73 cell division cycle 73 1.65831
ZNF552 zinc finger protein 552 1.65715
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 1.65626
PMVK phosphomevalonate kinase 1.65523
NEK4 NIMA-related kinase 4 1.65435
ENSA endosulfine alpha 1.65072
INTS12 integrator complex subunit 12 1.64484
SCD5 stearoyl-CoA desaturase 5 1.64428
LCE2B late cornified envelope 2B 1.64308
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 1.6425
GPR21 G protein-coupled receptor 21 1.63388
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1 1.62506
ANKZF1 ankyrin repeat and zinc finger domain containing 1 1.62203
ZNF14 zinc finger protein 14 1.62141
MKL2 MKL/myocardin-like 2 1.6206
ZNF682 zinc finger protein 682 1.61661
CALML5 calmodulin-like 5 1.61532
ZNF280D zinc finger protein 280D 1.6121
TRIM45 tripartite motif containing 45 1.60983
GDAP2 ganglioside induced differentiation associated protein 2 1.60297
IQCE IQ motif containing E 1.60193
RAB4A RAB4A, member RAS oncogene family 1.59517
TOMM20 translocase of outer mitochondrial membrane 20 homolog (yeast) 1.59317
CRABP2 cellular retinoic acid binding protein 2 1.57913
LOC650293 seven transmembrane helix receptor 1.57249
HMGN1 high mobility group nucleosome binding domain 1 1.57088
FPR3 formyl peptide receptor 3 1.5683
THUMPD1 THUMP domain containing 1 1.56233
PLA2G2F phospholipase A2, group IIF 1.55584
MCHR1 melanin-concentrating hormone receptor 1 1.54787
TNFSF8 tumor necrosis factor (ligand) superfamily, member 8 1.54183
SNRPE small nuclear ribonucleoprotein polypeptide E 1.53502
CNOT6 CCR4-NOT transcription complex, subunit 6 1.53434
TMEM123 transmembrane protein 123 1.5337
APITD1 apoptosis-inducing, TAF9-like domain 1 1.53261
THTPA thiamine triphosphatase 1.52419
KRT36 keratin 36, type I 1.52234
OPN1SW opsin 1 (cone pigments), short-wave-sensitive 1.52054
ZNF480 zinc finger protein 480 1.52012
TPRKB TP53RK binding protein 1.51891
SNED1 sushi, nidogen and EGF-like domains 1 1.51839
PPAP2C phosphatidic acid phosphatase type 2C 1.51497
TDRKH tudor and KH domain containing 1.51275
HOXB9 homeobox B9 1.5123
PEG10 paternally expressed 10 1.50818
PDCD10 programmed cell death 10 1.50375
MED9 mediator complex subunit 9 1.50122
CFAP45 cilia and flagella associated protein 45 1.50085
ZNF665 zinc finger protein 665 1.49886
CLCNKB chloride channel, voltage-sensitive Kb 1.49838
LOC145678 uncharacterized LOC145678 1.49607
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase 1.49588
FAM20B family with sequence similarity 20, member B 1.49529
METTL13 methyltransferase like 13 1.49499
POU3F4 POU class 3 homeobox 4 1.49213
CDH10 cadherin 10, type 2 (T2-cadherin) 1.48982
ONECUT1 one cut homeobox 1 1.48947
CBX1 chromobox homolog 1 1.48835
NFYB nuclear transcription factor Y, beta 1.4869
PAQR5 progestin and adipoQ receptor family member V 1.48655
PASK PAS domain containing serine/threonine kinase 1.4849
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B 1.48489
PRLR prolactin receptor 1.48287
IFT22 intraflagellar transport 22 1.48263
CEP97 centrosomal protein 97kDa 1.47737
PAQR4 progestin and adipoQ receptor family member IV 1.47471
FANCC Fanconi anemia, complementation group C 1.4742
NET1 neuroepithelial cell transforming 1 1.47303
NFIX nuclear factor I/X (CCAAT-binding transcription factor) 1.47301
MARC1 mitochondrial amidoxime reducing component 1 1.46499
TCFL5 transcription factor-like 5 (basic helix-loop-helix) 1.46306
H2AFV H2A histone family, member V 1.4606
PPOX protoporphyrinogen oxidase 1.45992
ENTPD2 ectonucleoside triphosphate diphosphohydrolase 2 1.45983
LRRC31 leucine rich repeat containing 31 1.45804
FUS FUS RNA binding protein 1.45671
APOL5 apolipoprotein L, 5 1.45497
MPC2 mitochondrial pyruvate carrier 2 1.45495
HOXB5 homeobox B5 1.45463
ZNF20 zinc finger protein 20 1.45459
PRRC2C proline-rich coiled-coil 2C 1.4545
ZNF124 zinc finger protein 124 1.45183
FRAT2 frequently rearranged in advanced T-cell lymphomas 2 1.45103
CSNK1G1 casein kinase 1, gamma 1 1.44977
ABCB11 ATP-binding cassette, sub-family B (MDR/TAP), member 11 1.449
ULK2 unc-51 like autophagy activating kinase 2 1.44684
TOB1 transducer of ERBB2, 1 1.4463
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1 1.44377
MGC40069 uncharacterized protein MGC40069 1.44342
PEX11B peroxisomal biogenesis factor 11 beta 1.44272
STX6 syntaxin 6 1.44125
PDAP1 PDGFA associated protein 1 1.44079
CKMT2 creatine kinase, mitochondrial 2 (sarcomeric) 1.44039
DYNLT1 dynein, light chain, Tctex-type 1 1.4375
CREB1 cAMP responsive element binding protein 1 1.43699
NR2C2 nuclear receptor subfamily 2, group C, member 2 1.43677
SMG7-AS1 SMG7 antisense RNA 1 1.43373
SLC44A4 solute carrier family 44, member 4 1.43339
AHSP alpha hemoglobin stabilizing protein 1.43254
CRYM crystallin, mu 1.43177
DKFZP586I1420 uncharacterized protein DKFZp586I1420 1.4314
ADCK3 aarF domain containing kinase 3 1.43096
TIMM17A translocase of inner mitochondrial membrane 17 homolog A (yeast) 1.43054
MGST3 microsomal glutathione S-transferase 3 1.42986
RORC RAR-related orphan receptor C 1.42917
UGT8 UDP glycosyltransferase 8 1.42505
PUM1 pumilio RNA-binding family member 1 1.42366
SOX4 SRY (sex determining region Y)-box 4 1.42361
PTMA prothymosin, alpha 1.42356
IRX5 iroquois homeobox 5 1.42211
CPT2 carnitine palmitoyltransferase 2 1.4204
PHYH phytanoyl-CoA 2-hydroxylase 1.41911
IPO9 importin 9 1.4182

low expression

Symbol Name Standardized Value
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog -3.53725
SREK1IP1 SREK1-interacting protein 1 -3.51205
UBE4B ubiquitination factor E4B -3.22155
ATP10D ATPase, class V, type 10D -3.20899
LMO4 LIM domain only 4 -3.12078
BICD1 bicaudal D homolog 1 (Drosophila) -2.9789
SLC9A6 solute carrier family 9, subfamily A (NHE6, cation proton antiporter 6), member 6 -2.92409
CSNK2A2 casein kinase 2, alpha prime polypeptide -2.78979
FBXO7 F-box protein 7 -2.77026
SNX6 sorting nexin 6 -2.73444
NUDT15 nudix (nucleoside diphosphate linked moiety X)-type motif 15 -2.72467
GDF11 growth differentiation factor 11 -2.52929
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3 -2.51022
GPATCH3 G patch domain containing 3 -2.44362
PDE4A phosphodiesterase 4A, cAMP-specific -2.40472
CEBPB CCAAT/enhancer binding protein (C/EBP), beta -2.35492
ERCC3 excision repair cross-complementation group 3 -2.3458
PI4K2A phosphatidylinositol 4-kinase type 2 alpha -2.34566
GLG1 golgi glycoprotein 1 -2.25072
DNAJB14 DnaJ (Hsp40) homolog, subfamily B, member 14 -2.17123
PITPNB phosphatidylinositol transfer protein, beta -2.16585
BTN3A3 butyrophilin, subfamily 3, member A3 -2.15774
HLA-DMA major histocompatibility complex, class II, DM alpha -2.13197
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1 -2.12187
CHD9 chromodomain helicase DNA binding protein 9 -2.11624
KCNH6 potassium channel, voltage gated eag related subfamily H, member 6 -2.11232
MANBA mannosidase, beta A, lysosomal -2.10162
E2F4 E2F transcription factor 4, p107/p130-binding -2.0752
ATHL1 ATH1, acid trehalase-like 1 (yeast) -2.07111
CCDC88A coiled-coil domain containing 88A -2.04752
NPR1 natriuretic peptide receptor 1 -2.03867
APBA3 amyloid beta (A4) precursor protein-binding, family A, member 3 -2.03114
SARM1 sterile alpha and TIR motif containing 1 -2.02049
MRC2 mannose receptor, C type 2 -2.02006
TERF2IP telomeric repeat binding factor 2, interacting protein -1.95072
TMCC2 transmembrane and coiled-coil domain family 2 -1.94841
CLCA1 chloride channel accessory 1 -1.94785
SRPX2 sushi-repeat containing protein, X-linked 2 -1.92211
KRT6B keratin 6B, type II -1.9132
MBTD1 mbt domain containing 1 -1.90943
JRKL JRK-like -1.9045
FCHSD2 FCH and double SH3 domains 2 -1.9015
PPP1R15A protein phosphatase 1, regulatory subunit 15A -1.88844
IFI6 interferon, alpha-inducible protein 6 -1.88171
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide -1.86268
FAM65A family with sequence similarity 65, member A -1.86239
KIAA0319L KIAA0319-like -1.85928
TFIP11 tuftelin interacting protein 11 -1.84867
MAPK12 mitogen-activated protein kinase 12 -1.8378
ATP6V1E1 ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1 -1.82658
BAG2 BCL2-associated athanogene 2 -1.82172
SYNPO synaptopodin -1.81611
SGK3 serum/glucocorticoid regulated kinase family, member 3 -1.80862
MOSPD2 motile sperm domain containing 2 -1.80726
AP5Z1 adaptor-related protein complex 5, zeta 1 subunit -1.79764
POLR2C polymerase (RNA) II (DNA directed) polypeptide C, 33kDa -1.78639
ADD3 adducin 3 (gamma) -1.77864
FRS3 fibroblast growth factor receptor substrate 3 -1.77728
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 -1.77149
DHRS2 dehydrogenase/reductase (SDR family) member 2 -1.7677
PPP2R2A protein phosphatase 2, regulatory subunit B, alpha -1.76092
TNC tenascin C -1.74267
GTPBP8 GTP-binding protein 8 (putative) -1.73966
SIRT6 sirtuin 6 -1.73702
PSMD14 proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 -1.73642
MAP6D1 MAP6 domain containing 1 -1.73103
DDX18 DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 -1.72217
FAM96B family with sequence similarity 96, member B -1.72027
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b -1.71666
PPP3CC protein phosphatase 3, catalytic subunit, gamma isozyme -1.69948
MRPL52 mitochondrial ribosomal protein L52 -1.69675
IFI35 interferon-induced protein 35 -1.69178
ATP8A2 ATPase, aminophospholipid transporter, class I, type 8A, member 2 -1.68979
ANP32E acidic (leucine-rich) nuclear phosphoprotein 32 family, member E -1.68232
UBA5 ubiquitin-like modifier activating enzyme 5 -1.67759
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 -1.6749
THAP7 THAP domain containing 7 -1.67354
JADE2 jade family PHD finger 2 -1.66863
NPY2R neuropeptide Y receptor Y2 -1.6606
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 -1.65786
LONRF1 LON peptidase N-terminal domain and ring finger 1 -1.64792
USP11 ubiquitin specific peptidase 11 -1.64539
MGAT1 mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase -1.64051
DERL1 derlin 1 -1.63355
NMT1 N-myristoyltransferase 1 -1.63135
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) -1.62434
PEG3 paternally expressed 3 -1.62192
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8 -1.62174
MRPL40 mitochondrial ribosomal protein L40 -1.60531
ADSL adenylosuccinate lyase -1.59242
HRK harakiri, BCL2 interacting protein -1.59018
ACTR3 ARP3 actin-related protein 3 homolog (yeast) -1.58312
CENPT centromere protein T -1.57306
SYT1 synaptotagmin I -1.57298
YARS tyrosyl-tRNA synthetase -1.57201
CXCL8 chemokine (C-X-C motif) ligand 8 -1.57055
DDX19A DEAD (Asp-Glu-Ala-Asp) box polypeptide 19A -1.5667
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1 -1.55474
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1) -1.5512
PXMP4 peroxisomal membrane protein 4, 24kDa -1.55058
MKL1 megakaryoblastic leukemia (translocation) 1 -1.54733
SMAD3 SMAD family member 3 -1.54632
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive -1.54454
POLDIP3 polymerase (DNA-directed), delta interacting protein 3 -1.54374
COPG1 coatomer protein complex, subunit gamma 1 -1.53812
CRTC1 CREB regulated transcription coactivator 1 -1.53521
SQLE squalene epoxidase -1.53367
PODNL1 podocan-like 1 -1.53271
MPI mannose phosphate isomerase -1.53047
AARS alanyl-tRNA synthetase -1.52462
EIF3D eukaryotic translation initiation factor 3, subunit D -1.52199
COMT catechol-O-methyltransferase -1.51742
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) -1.51686
ATF4 activating transcription factor 4 -1.51618
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 -1.51181
AGXT alanine-glyoxylate aminotransferase -1.50679
NPL N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase) -1.48947
UBA1 ubiquitin-like modifier activating enzyme 1 -1.48266
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) -1.47222
APOL1 apolipoprotein L, 1 -1.47175
TERF2 telomeric repeat binding factor 2 -1.46834
ARL5A ADP-ribosylation factor-like 5A -1.46729
FDFT1 farnesyl-diphosphate farnesyltransferase 1 -1.46605
SIK1 salt-inducible kinase 1 -1.4616
CYB5B cytochrome b5 type B (outer mitochondrial membrane) -1.4549
COPS7A COP9 signalosome subunit 7A -1.45217
DST dystonin -1.43708
UXS1 UDP-glucuronate decarboxylase 1 -1.4349
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2 -1.43453
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae) -1.43368
TARBP2 TAR (HIV-1) RNA binding protein 2 -1.43152
TBKBP1 TBK1 binding protein 1 -1.42763
PES1 pescadillo ribosomal biogenesis factor 1 -1.42545
ACO1 aconitase 1, soluble -1.42282
S100A4 S100 calcium binding protein A4 -1.41878