CAL-62 Gene Set

Dataset COSMIC Cell Line Gene Mutation Profiles
Category genomics
Type cell line
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Genes

304 genes mutated in the CAL-62 cell line from the COSMIC Cell Line Gene Mutation Profiles dataset.

Symbol Name
ABCB5 ATP-binding cassette, sub-family B (MDR/TAP), member 5
ABLIM2 actin binding LIM protein family, member 2
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2
ACSL1 acyl-CoA synthetase long-chain family member 1
ADAMTS12 ADAM metallopeptidase with thrombospondin type 1 motif, 12
ADAMTS14 ADAM metallopeptidase with thrombospondin type 1 motif, 14
ADCY6 adenylate cyclase 6
ADD3 adducin 3 (gamma)
ADGB androglobin
ADGRA1 adhesion G protein-coupled receptor A1
ADGRG4 adhesion G protein-coupled receptor G4
AHNAK2 AHNAK nucleoprotein 2
AIFM3 apoptosis-inducing factor, mitochondrion-associated, 3
ALX4 ALX homeobox 4
AMICA1 adhesion molecule, interacts with CXADR antigen 1
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
ANKHD1 ankyrin repeat and KH domain containing 1
ANKHD1-EIF4EBP3 ANKHD1-EIF4EBP3 readthrough
ANKRD18A ankyrin repeat domain 18A
ANXA4 annexin A4
AOC2 amine oxidase, copper containing 2 (retina-specific)
APP amyloid beta (A4) precursor protein
AR androgen receptor
ARHGAP20 Rho GTPase activating protein 20
ARL11 ADP-ribosylation factor-like 11
ASF1B anti-silencing function 1B histone chaperone
ASPN asporin
ATP13A4 ATPase type 13A4
ATP2A1 ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
ATP6V1C1 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1
AVL9 AVL9 homolog (S. cerevisiase)
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
B4GALNT4 beta-1,4-N-acetyl-galactosaminyl transferase 4
BBS10 Bardet-Biedl syndrome 10
BTBD9 BTB (POZ) domain containing 9
C6 complement component 6
C8A complement component 8, alpha polypeptide
CABP5 calcium binding protein 5
CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
CALD1 caldesmon 1
CCDC74A coiled-coil domain containing 74A
CD38 CD38 molecule
CDC25C cell division cycle 25C
CDC42BPB CDC42 binding protein kinase beta (DMPK-like)
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDYL chromodomain protein, Y-like
CELA3B chymotrypsin-like elastase family, member 3B
CENPL centromere protein L
CEP295 centrosomal protein 295kDa
CFAP46 cilia and flagella associated protein 46
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
CIZ1 CDKN1A interacting zinc finger protein 1
CNTN4 contactin 4
COL11A1 collagen, type XI, alpha 1
COL24A1 collagen, type XXIV, alpha 1
COL4A2 collagen, type IV, alpha 2
COL6A6 collagen, type VI, alpha 6
COMT catechol-O-methyltransferase
CPNE7 copine VII
CREBBP CREB binding protein
CSMD3 CUB and Sushi multiple domains 3
CSPG4 chondroitin sulfate proteoglycan 4
CWC25 CWC25 spliceosome-associated protein homolog (S. cerevisiae)
CYP4F12 cytochrome P450, family 4, subfamily F, polypeptide 12
CYR61 cysteine-rich, angiogenic inducer, 61
DCAF15 DDB1 and CUL4 associated factor 15
DDX12P DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 12, pseudogene
DIP2C DIP2 disco-interacting protein 2 homolog C (Drosophila)
DLK2 delta-like 2 homolog (Drosophila)
DNAH11 dynein, axonemal, heavy chain 11
DROSHA drosha, ribonuclease type III
DST dystonin
DVL1 dishevelled segment polarity protein 1
EDC4 enhancer of mRNA decapping 4
EFCAB9 EF-hand calcium binding domain 9
ENAM enamelin
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
EP300 E1A binding protein p300
EPHA3 EPH receptor A3
EYS eyes shut homolog (Drosophila)
FAM135B family with sequence similarity 135, member B
FAM172A family with sequence similarity 172, member A
FAM196B family with sequence similarity 196, member B
FAM71C family with sequence similarity 71, member C
FAT4 FAT atypical cadherin 4
FBF1 Fas (TNFRSF6) binding factor 1
FIGN fidgetin
FLNC filamin C, gamma
FLT4 fms-related tyrosine kinase 4
FOLR2 folate receptor 2 (fetal)
FREM3 FRAS1 related extracellular matrix 3
G3BP2 GTPase activating protein (SH3 domain) binding protein 2
GABRG2 gamma-aminobutyric acid (GABA) A receptor, gamma 2
GAREML GRB2 associated, regulator of MAPK1-like
GBAP1 glucosidase, beta, acid pseudogene 1
GCC1 GRIP and coiled-coil domain containing 1
GLB1L galactosidase, beta 1-like
GLB1L3 galactosidase, beta 1-like 3
GPR3 G protein-coupled receptor 3
GPR87 G protein-coupled receptor 87
GRIA1 glutamate receptor, ionotropic, AMPA 1
GRIN2D glutamate receptor, ionotropic, N-methyl D-aspartate 2D
GSTK1 glutathione S-transferase kappa 1
GTF2IRD1 GTF2I repeat domain containing 1
GTF3C1 general transcription factor IIIC, polypeptide 1, alpha 220kDa
GXYLT2 glucoside xylosyltransferase 2
HCAR1 hydroxycarboxylic acid receptor 1
HDAC4 histone deacetylase 4
HFE2 hemochromatosis type 2 (juvenile)
HIST1H1D histone cluster 1, H1d
HIST1H2BG histone cluster 1, H2bg
HLA-C major histocompatibility complex, class I, C
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HOXA5 homeobox A5
HOXC10 homeobox C10
HSD3B1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
IDH3G isocitrate dehydrogenase 3 (NAD+) gamma
IGSF1 immunoglobulin superfamily, member 1
INHBA inhibin, beta A
KAT2A K(lysine) acetyltransferase 2A
KAT6A K(lysine) acetyltransferase 6A
KAT6B K(lysine) acetyltransferase 6B
KIAA0895 KIAA0895
KIAA1671 KIAA1671
KIF13B kinesin family member 13B
KIR2DL1 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1
KL klotho
KLF6 Kruppel-like factor 6
KLHL28 kelch-like family member 28
KMT2C lysine (K)-specific methyltransferase 2C
KRAS Kirsten rat sarcoma viral oncogene homolog
KRBA1 KRAB-A domain containing 1
KRT40 keratin 40, type I
KRTAP4-1 keratin associated protein 4-1
KRTAP5-1 keratin associated protein 5-1
KRTAP9-4 keratin associated protein 9-4
KY kyphoscoliosis peptidase
LCNL1 lipocalin-like 1
LIG1 ligase I, DNA, ATP-dependent
LOXL2 lysyl oxidase-like 2
LPPR5 lipid phosphate phosphatase-related protein type 5
LRRK2 leucine-rich repeat kinase 2
LTA lymphotoxin alpha
MAGEA12 melanoma antigen family A12
MAP4 microtubule-associated protein 4
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1
MAPRE2 microtubule-associated protein, RP/EB family, member 2
MEF2A myocyte enhancer factor 2A
MERTK MER proto-oncogene, tyrosine kinase
MFN1 mitofusin 1
MGA MGA, MAX dimerization protein
MICU3 mitochondrial calcium uptake family, member 3
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
MORC2 MORC family CW-type zinc finger 2
MRPL28 mitochondrial ribosomal protein L28
MUC16 mucin 16, cell surface associated
MUC4 mucin 4, cell surface associated
MVP major vault protein
MYO5B myosin VB
NAAA N-acylethanolamine acid amidase
NAALADL1 N-acetylated alpha-linked acidic dipeptidase-like 1
NAALADL2 N-acetylated alpha-linked acidic dipeptidase-like 2
NANOS2 nanos homolog 2 (Drosophila)
NAPSA napsin A aspartic peptidase
NF2 neurofibromin 2 (merlin)
NIN ninein (GSK3B interacting protein)
NKX2-2 NK2 homeobox 2
NLRP2 NLR family, pyrin domain containing 2
NME7 NME/NM23 family member 7
NOD1 nucleotide-binding oligomerization domain containing 1
NPC1L1 NPC1-like 1
NPHP3 nephronophthisis 3 (adolescent)
NRIP1 nuclear receptor interacting protein 1
NUP107 nucleoporin 107kDa
NWD1 NACHT and WD repeat domain containing 1
OBSCN obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
OPCML opioid binding protein/cell adhesion molecule-like
OR12D2 olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene)
OR2AG1 olfactory receptor, family 2, subfamily AG, member 1 (gene/pseudogene)
OR4C3 olfactory receptor, family 4, subfamily C, member 3
OR4M2 olfactory receptor, family 4, subfamily M, member 2
OR52K2 olfactory receptor, family 52, subfamily K, member 2
OR5P3 olfactory receptor, family 5, subfamily P, member 3
OXA1L oxidase (cytochrome c) assembly 1-like
PACS2 phosphofurin acidic cluster sorting protein 2
PAPD5 PAP associated domain containing 5
PAPPA pregnancy-associated plasma protein A, pappalysin 1
PARP12 poly (ADP-ribose) polymerase family, member 12
PASK PAS domain containing serine/threonine kinase
PCBP4 poly(rC) binding protein 4
PCDHB10 protocadherin beta 10
PCDHGA6 protocadherin gamma subfamily A, 6
PDP2 pyruvate dehyrogenase phosphatase catalytic subunit 2
PGA4 pepsinogen 4, group I (pepsinogen A)
PGA5 pepsinogen 5, group I (pepsinogen A)
PIEZO1 piezo-type mechanosensitive ion channel component 1
PIWIL1 piwi-like RNA-mediated gene silencing 1
PKHD1L1 polycystic kidney and hepatic disease 1 (autosomal recessive)-like 1
PKP4 plakophilin 4
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLEKHA6 pleckstrin homology domain containing, family A member 6
PLIN3 perilipin 3
PLXNA1 plexin A1
PNISR PNN-interacting serine/arginine-rich protein
POLE polymerase (DNA directed), epsilon, catalytic subunit
POLQ polymerase (DNA directed), theta
POM121L2 POM121 transmembrane nucleoporin-like 2
POTEH POTE ankyrin domain family, member H
POTEI POTE ankyrin domain family, member I
POU2F2 POU class 2 homeobox 2
PRDX2 peroxiredoxin 2
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PRSS16 protease, serine, 16 (thymus)
PSME4 proteasome (prosome, macropain) activator subunit 4
PTPRN protein tyrosine phosphatase, receptor type, N
QARS glutaminyl-tRNA synthetase
RAB11FIP3 RAB11 family interacting protein 3 (class II)
RAD9B RAD9 homolog B (S. pombe)
RALGAPB Ral GTPase activating protein, beta subunit (non-catalytic)
RAPGEF1 Rap guanine nucleotide exchange factor (GEF) 1
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated)
RASGRP4 RAS guanyl releasing protein 4
RASIP1 Ras interacting protein 1
RASSF2 Ras association (RalGDS/AF-6) domain family member 2
RHPN2 rhophilin, Rho GTPase binding protein 2
RIF1 replication timing regulatory factor 1
RSPH3 radial spoke 3 homolog (Chlamydomonas)
RTTN rotatin
SDK1 sidekick cell adhesion molecule 1
SEC23B Sec23 homolog B (S. cerevisiae)
SEMA3D sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D
SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
SENP7 SUMO1/sentrin specific peptidase 7
SERF2 small EDRK-rich factor 2
SETD5 SET domain containing 5
SFTPB surfactant protein B
SIX4 SIX homeobox 4
SLC17A2 solute carrier family 17, member 2
SLC38A1 solute carrier family 38, member 1
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SLC52A1 solute carrier family 52 (riboflavin transporter), member 1
SLC9A5 solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5
SLCO4A1 solute carrier organic anion transporter family, member 4A1
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B
SORCS1 sortilin-related VPS10 domain containing receptor 1
SOX10 SRY (sex determining region Y)-box 10
SOX3 SRY (sex determining region Y)-box 3
SPECC1 sperm antigen with calponin homology and coiled-coil domains 1
SPIDR scaffolding protein involved in DNA repair
SPNS1 spinster homolog 1 (Drosophila)
SPRED1 sprouty-related, EVH1 domain containing 1
SRCAP Snf2-related CREBBP activator protein
SSTR4 somatostatin receptor 4
STAG3 stromal antigen 3
STARD9 StAR-related lipid transfer (START) domain containing 9
STX7 syntaxin 7
SUN2 Sad1 and UNC84 domain containing 2
SYNE1 spectrin repeat containing, nuclear envelope 1
SYNE3 spectrin repeat containing, nuclear envelope family member 3
SYT16 synaptotagmin XVI
TAF1C TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa
TAOK2 TAO kinase 2
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TF transferrin
THAP4 THAP domain containing 4
THNSL2 threonine synthase-like 2 (S. cerevisiae)
THRAP3 thyroid hormone receptor associated protein 3
TIE1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1
TMPRSS6 transmembrane protease, serine 6
TP53 tumor protein p53
TRERF1 transcriptional regulating factor 1
TRIM39 tripartite motif containing 39
TRIM49B tripartite motif containing 49B
TRIP6 thyroid hormone receptor interactor 6
TRPM8 transient receptor potential cation channel, subfamily M, member 8
TSC2 tuberous sclerosis 2
TUBB8 tubulin, beta 8 class VIII
UBE2NL ubiquitin-conjugating enzyme E2N-like (gene/pseudogene)
UBR4 ubiquitin protein ligase E3 component n-recognin 4
UBXN8 UBX domain protein 8
UHRF1BP1L UHRF1 binding protein 1-like
USH2A Usher syndrome 2A (autosomal recessive, mild)
USP13 ubiquitin specific peptidase 13 (isopeptidase T-3)
USP29 ubiquitin specific peptidase 29
USP44 ubiquitin specific peptidase 44
VIL1 villin 1
VPS13D vacuolar protein sorting 13 homolog D (S. cerevisiae)
WDR73 WD repeat domain 73
WDR81 WD repeat domain 81
WDR90 WD repeat domain 90
WDSUB1 WD repeat, sterile alpha motif and U-box domain containing 1
WFIKKN2 WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2
ZBTB44 zinc finger and BTB domain containing 44
ZEB1 zinc finger E-box binding homeobox 1
ZFHX4 zinc finger homeobox 4
ZFYVE28 zinc finger, FYVE domain containing 28
ZNF276 zinc finger protein 276
ZNF311 zinc finger protein 311
ZNF616 zinc finger protein 616
ZNF639 zinc finger protein 639
ZNF646 zinc finger protein 646
ZNF687 zinc finger protein 687
ZSCAN30 zinc finger and SCAN domain containing 30