CAL-62 Gene Set

Dataset GDSC Cell Line Gene Expression Profiles
Category transcriptomics
Type cell line
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Genes

347 genes with high or low expression in CAL-62 relative to other cell lines from the GDSC Cell Line Gene Expression Profiles dataset.

high expression

Symbol Name Standardized Value
SREK1 splicing regulatory glutamine/lysine-rich protein 1 3.60177
AP3S2 adaptor-related protein complex 3, sigma 2 subunit 3.52549
UPF1 UPF1 regulator of nonsense transcripts homolog (yeast) 3.0363
MAP3K9 mitogen-activated protein kinase kinase kinase 9 2.75147
PLCG1 phospholipase C, gamma 1 2.50933
UBOX5 U-box domain containing 5 2.41865
SLC16A8 solute carrier family 16 (monocarboxylate transporter), member 8 2.41863
TMED1 transmembrane emp24 protein transport domain containing 1 2.39388
LTBP3 latent transforming growth factor beta binding protein 3 2.38401
ATG13 autophagy related 13 2.36188
PMPCA peptidase (mitochondrial processing) alpha 2.36102
ARFGAP1 ADP-ribosylation factor GTPase activating protein 1 2.35577
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1 2.33883
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein 2.31224
TJAP1 tight junction associated protein 1 (peripheral) 2.30223
HMGA1 high mobility group AT-hook 1 2.29517
IRF7 interferon regulatory factor 7 2.25447
IFIT5 interferon-induced protein with tetratricopeptide repeats 5 2.22641
SNRPB small nuclear ribonucleoprotein polypeptides B and B1 2.22383
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17 2.20061
UNC45A unc-45 homolog A (C. elegans) 2.19786
PLAU plasminogen activator, urokinase 2.19708
CMTR1 cap methyltransferase 1 2.17651
CCR10 chemokine (C-C motif) receptor 10 2.17313
TRIM21 tripartite motif containing 21 2.16721
PNPLA2 patatin-like phospholipase domain containing 2 2.16075
PARP12 poly (ADP-ribose) polymerase family, member 12 2.13731
ZFR2 zinc finger RNA binding protein 2 2.11795
VPS16 vacuolar protein sorting 16 homolog (S. cerevisiae) 2.10382
CPNE1 copine I 2.09766
CRTC1 CREB regulated transcription coactivator 1 2.09394
PDPN podoplanin 2.06972
SLC20A1 solute carrier family 20 (phosphate transporter), member 1 2.06581
ZNF133 zinc finger protein 133 2.05994
PTPRA protein tyrosine phosphatase, receptor type, A 2.03943
MIER2 mesoderm induction early response 1, family member 2 2.03552
DEAF1 DEAF1 transcription factor 2.01017
TADA3 transcriptional adaptor 3 2.00414
MFGE8 milk fat globule-EGF factor 8 protein 1.97556
TAF7L TAF7-like RNA polymerase II, TATA box binding protein (TBP)-associated factor, 50kDa 1.96521
MORC2 MORC family CW-type zinc finger 2 1.95647
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3 1.95039
TK2 thymidine kinase 2, mitochondrial 1.94947
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3 1.94818
KRT84 keratin 84, type II 1.93406
PAPD4 PAP associated domain containing 4 1.93108
ZER1 zyg-11 related, cell cycle regulator 1.92648
RGN regucalcin 1.92595
POLG polymerase (DNA directed), gamma 1.92018
SCAMP4 secretory carrier membrane protein 4 1.91126
PRPF4B pre-mRNA processing factor 4B 1.90996
PEX16 peroxisomal biogenesis factor 16 1.90725
TGM2 transglutaminase 2 1.90041
ARPC4 actin related protein 2/3 complex, subunit 4, 20kDa 1.8997
DGCR14 DiGeorge syndrome critical region gene 14 1.88897
CDK5RAP1 CDK5 regulatory subunit associated protein 1 1.88835
SPON1 spondin 1, extracellular matrix protein 1.88758
HINFP histone H4 transcription factor 1.87906
MED27 mediator complex subunit 27 1.86468
PHF1 PHD finger protein 1 1.86298
PIGZ phosphatidylinositol glycan anchor biosynthesis, class Z 1.86057
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) 1.85968
TBC1D13 TBC1 domain family, member 13 1.84887
GPX4 glutathione peroxidase 4 1.84538
MT1M metallothionein 1M 1.84239
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 1.83618
LPPR2 lipid phosphate phosphatase-related protein type 2 1.82783
RAPGEF3 Rap guanine nucleotide exchange factor (GEF) 3 1.82257
BTBD2 BTB (POZ) domain containing 2 1.81142
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5 1.8009
PAOX polyamine oxidase (exo-N4-amino) 1.79645
VGLL4 vestigial-like family member 4 1.79447
EFEMP2 EGF containing fibulin-like extracellular matrix protein 2 1.78622
NPEPPS aminopeptidase puromycin sensitive 1.78484
PANK2 pantothenate kinase 2 1.78455
AAMP angio-associated, migratory cell protein 1.78251
SIPA1L1 signal-induced proliferation-associated 1 like 1 1.76136
SCP2 sterol carrier protein 2 1.75754
ARAP3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 1.73699
CLIP2 CAP-GLY domain containing linker protein 2 1.73132
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase 1.71914
SLC30A1 solute carrier family 30 (zinc transporter), member 1 1.71881
ZNF148 zinc finger protein 148 1.71316
MEA1 male-enhanced antigen 1 1.70913
ALPK3 alpha-kinase 3 1.70677
APBA3 amyloid beta (A4) precursor protein-binding, family A, member 3 1.7044
LRCH3 leucine-rich repeats and calponin homology (CH) domain containing 3 1.70282
MMP24 matrix metallopeptidase 24 (membrane-inserted) 1.70072
RAB1B RAB1B, member RAS oncogene family 1.70049
PSKH1 protein serine kinase H1 1.69828
BRPF1 bromodomain and PHD finger containing, 1 1.69528
UBA7 ubiquitin-like modifier activating enzyme 7 1.69522
GCK glucokinase (hexokinase 4) 1.69381
LTBR lymphotoxin beta receptor (TNFR superfamily, member 3) 1.68984
APOC3 apolipoprotein C-III 1.68706
MINK1 misshapen-like kinase 1 1.68481
LDB1 LIM domain binding 1 1.68267
ZNF408 zinc finger protein 408 1.67448
SKIL SKI-like proto-oncogene 1.67145
OGFR opioid growth factor receptor 1.66823
SCO2 SCO2 cytochrome c oxidase assembly protein 1.6595
ACTL7A actin-like 7A 1.6591
CRBN cereblon 1.65802
INPPL1 inositol polyphosphate phosphatase-like 1 1.65238
DMWD dystrophia myotonica, WD repeat containing 1.64599
COLQ collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase 1.64374
MT1H metallothionein 1H 1.64218
COG7 component of oligomeric golgi complex 7 1.64186
NEFH neurofilament, heavy polypeptide 1.63834
PAX8 paired box 8 1.63469
CARS cysteinyl-tRNA synthetase 1.63436
MT1X metallothionein 1X 1.63432
RBM23 RNA binding motif protein 23 1.62251
MED16 mediator complex subunit 16 1.62135
GDI1 GDP dissociation inhibitor 1 1.62033
IFITM3 interferon induced transmembrane protein 3 1.62011
CSNK1G2 casein kinase 1, gamma 2 1.61372
DCAF10 DDB1 and CUL4 associated factor 10 1.60793
NSFL1C NSFL1 (p97) cofactor (p47) 1.60211
MAU2 MAU2 sister chromatid cohesion factor 1.59894
TM2D3 TM2 domain containing 3 1.59486
MT1E metallothionein 1E 1.59315
NUP98 nucleoporin 98kDa 1.58897
IQGAP1 IQ motif containing GTPase activating protein 1 1.58874
NELFB negative elongation factor complex member B 1.58691
RXRB retinoid X receptor, beta 1.58451
RUFY1 RUN and FYVE domain containing 1 1.58371
ARL2 ADP-ribosylation factor-like 2 1.58222
ZC3H3 zinc finger CCCH-type containing 3 1.58185
SIN3B SIN3 transcription regulator family member B 1.58134
IFITM1 interferon induced transmembrane protein 1 1.57324
NUBPL nucleotide binding protein-like 1.57078
GMEB2 glucocorticoid modulatory element binding protein 2 1.56678
SLC6A1 solute carrier family 6 (neurotransmitter transporter), member 1 1.55906
RHBDF1 rhomboid 5 homolog 1 (Drosophila) 1.55882
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma 1.55717
PFDN1 prefoldin subunit 1 1.5533
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 1.54964
RAMP2 receptor (G protein-coupled) activity modifying protein 2 1.54848
GAS6 growth arrest-specific 6 1.54644
NPEPL1 aminopeptidase-like 1 1.54208
SIRPB1 signal-regulatory protein beta 1 1.54183
CAMTA2 calmodulin binding transcription activator 2 1.54169
KIF3B kinesin family member 3B 1.54073
GRINA glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding) 1.53794
TRPV1 transient receptor potential cation channel, subfamily V, member 1 1.53241
CALM3 calmodulin 3 (phosphorylase kinase, delta) 1.52983
TEX10 testis expressed 10 1.52938
PLXNA1 plexin A1 1.52921
YIPF3 Yip1 domain family, member 3 1.52782
HIST1H2BG histone cluster 1, H2bg 1.52394
AREL1 apoptosis resistant E3 ubiquitin protein ligase 1 1.52349
VPS11 vacuolar protein sorting 11 homolog (S. cerevisiae) 1.51719
KCNA10 potassium channel, voltage gated shaker related subfamily A, member 10 1.51599
ARL8B ADP-ribosylation factor-like 8B 1.51072
RABGAP1 RAB GTPase activating protein 1 1.5091
CRAT carnitine O-acetyltransferase 1.50821
MTCH1 mitochondrial carrier 1 1.50766
MT1G metallothionein 1G 1.50699
ZSWIM1 zinc finger, SWIM-type containing 1 1.50621
SH2B1 SH2B adaptor protein 1 1.4995
EFCC1 EF-hand and coiled-coil domain containing 1 1.49719
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37 1.49515
PMEPA1 prostate transmembrane protein, androgen induced 1 1.49501
CENPB centromere protein B, 80kDa 1.49439
RBM39 RNA binding motif protein 39 1.49391
RAB36 RAB36, member RAS oncogene family 1.49326
ASTE1 asteroid homolog 1 (Drosophila) 1.49231
NPC2 Niemann-Pick disease, type C2 1.49008
L3MBTL1 l(3)mbt-like 1 (Drosophila) 1.48469
ORAI3 ORAI calcium release-activated calcium modulator 3 1.48403
UBE2L6 ubiquitin-conjugating enzyme E2L 6 1.48089
GPRC5C G protein-coupled receptor, class C, group 5, member C 1.47863
IFI6 interferon, alpha-inducible protein 6 1.47473
EML3 echinoderm microtubule associated protein like 3 1.47324
SLC8A2 solute carrier family 8 (sodium/calcium exchanger), member 2 1.47283
GTPBP3 GTP binding protein 3 (mitochondrial) 1.46951
NPFF neuropeptide FF-amide peptide precursor 1.46762
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2) 1.46755
MED22 mediator complex subunit 22 1.46599
TLL2 tolloid-like 2 1.46458
ASNA1 arsA arsenite transporter, ATP-binding, homolog 1 (bacterial) 1.46429
SIRPG signal-regulatory protein gamma 1.4583
LSP1 lymphocyte-specific protein 1 1.45614
DMTN dematin actin binding protein 1.45417
TBL3 transducin (beta)-like 3 1.44874
DHX34 DEAH (Asp-Glu-Ala-His) box polypeptide 34 1.44649
PTOV1 prostate tumor overexpressed 1 1.44208
OTUB1 OTU deubiquitinase, ubiquitin aldehyde binding 1 1.44103
PLEKHA4 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 1.43931
AMH anti-Mullerian hormone 1.43917
ABR active BCR-related 1.43498
ZNF202 zinc finger protein 202 1.43176
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta 1.43
BNC2 basonuclin 2 1.42957
TH tyrosine hydroxylase 1.42884
CLCF1 cardiotrophin-like cytokine factor 1 1.42662
DAPK2 death-associated protein kinase 2 1.42642
ZNF446 zinc finger protein 446 1.42443
RHOF ras homolog family member F (in filopodia) 1.42198
TGFB1I1 transforming growth factor beta 1 induced transcript 1 1.42198
ZC3HAV1 zinc finger CCCH-type, antiviral 1 1.42065
ZNF224 zinc finger protein 224 1.4206
PLSCR1 phospholipid scramblase 1 1.42056
PRKRIP1 PRKR interacting protein 1 (IL11 inducible) 1.41859
UBXN7 UBX domain protein 7 1.41738

low expression

Symbol Name Standardized Value
PAFAH2 platelet-activating factor acetylhydrolase 2, 40kDa -3.48668
ZNF552 zinc finger protein 552 -3.41948
EFR3B EFR3 homolog B (S. cerevisiae) -2.99257
POP5 processing of precursor 5, ribonuclease P/MRP subunit (S. cerevisiae) -2.63218
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase -2.6003
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit -2.53336
TIAM2 T-cell lymphoma invasion and metastasis 2 -2.49602
ABCD3 ATP-binding cassette, sub-family D (ALD), member 3 -2.49077
KLHL7 kelch-like family member 7 -2.43196
DIP2C DIP2 disco-interacting protein 2 homolog C (Drosophila) -2.4142
EXO1 exonuclease 1 -2.40471
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8 -2.39024
TFB1M transcription factor B1, mitochondrial -2.38132
CHN2 chimerin 2 -2.20927
MAPK8 mitogen-activated protein kinase 8 -2.19695
AZIN1 antizyme inhibitor 1 -2.18608
QRSL1 glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1 -2.18495
ATP5F1 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1 -2.14957
SEL1L sel-1 suppressor of lin-12-like (C. elegans) -2.14837
NIT1 nitrilase 1 -2.14062
PAPPA2 pappalysin 2 -2.12927
MED4 mediator complex subunit 4 -2.11073
DNAJC10 DnaJ (Hsp40) homolog, subfamily C, member 10 -2.10956
JAM3 junctional adhesion molecule 3 -2.08261
NUP88 nucleoporin 88kDa -2.05547
AP4S1 adaptor-related protein complex 4, sigma 1 subunit -2.03728
RCAN3 RCAN family member 3 -2.019
CSTF2 cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa -1.99969
FAM76A family with sequence similarity 76, member A -1.99694
CRYAB crystallin, alpha B -1.99648
RGS16 regulator of G-protein signaling 16 -1.9854
POU2F2 POU class 2 homeobox 2 -1.9703
GLE1 GLE1 RNA export mediator -1.96656
TUBD1 tubulin, delta 1 -1.9321
PLA2G12A phospholipase A2, group XIIA -1.92865
SLC2A9 solute carrier family 2 (facilitated glucose transporter), member 9 -1.90625
ATXN3 ataxin 3 -1.87622
PGD phosphogluconate dehydrogenase -1.86803
MRPS15 mitochondrial ribosomal protein S15 -1.86645
ASTN2 astrotactin 2 -1.86554
MTMR2 myotubularin related protein 2 -1.8624
GLMN glomulin, FKBP associated protein -1.85677
FKBP3 FK506 binding protein 3, 25kDa -1.85342
SLC25A15 solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15 -1.84033
NRN1 neuritin 1 -1.83955
ENSA endosulfine alpha -1.81834
SH3GLB1 SH3-domain GRB2-like endophilin B1 -1.81142
PSMG1 proteasome (prosome, macropain) assembly chaperone 1 -1.79967
COMMD8 COMM domain containing 8 -1.78903
SORBS1 sorbin and SH3 domain containing 1 -1.78268
SMEK1 SMEK homolog 1, suppressor of mek1 (Dictyostelium) -1.77927
HAT1 histone acetyltransferase 1 -1.77108
YY1 YY1 transcription factor -1.76316
CPSF6 cleavage and polyadenylation specific factor 6, 68kDa -1.76126
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -1.75558
ZCCHC4 zinc finger, CCHC domain containing 4 -1.74315
APC adenomatous polyposis coli -1.74202
LONRF3 LON peptidase N-terminal domain and ring finger 3 -1.74101
NUP155 nucleoporin 155kDa -1.74087
CYCS cytochrome c, somatic -1.7368
LY96 lymphocyte antigen 96 -1.73266
DAP3 death associated protein 3 -1.72711
EAF2 ELL associated factor 2 -1.72195
METTL3 methyltransferase like 3 -1.72183
SERBP1 SERPINE1 mRNA binding protein 1 -1.71441
CUL3 cullin 3 -1.71323
GART phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase -1.71047
PAPOLA poly(A) polymerase alpha -1.70871
CENPJ centromere protein J -1.70202
CYTH4 cytohesin 4 -1.70099
STK17B serine/threonine kinase 17b -1.69848
GNL3 guanine nucleotide binding protein-like 3 (nucleolar) -1.69725
INTS7 integrator complex subunit 7 -1.6953
ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase -1.69438
ELP3 elongator acetyltransferase complex subunit 3 -1.6942
IL2RG interleukin 2 receptor, gamma -1.69248
SEC63 SEC63 homolog (S. cerevisiae) -1.68517
GOLGA5 golgin A5 -1.68363
AMD1 adenosylmethionine decarboxylase 1 -1.67298
IQGAP2 IQ motif containing GTPase activating protein 2 -1.67257
UBXN8 UBX domain protein 8 -1.67137
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5 -1.66412
CEP76 centrosomal protein 76kDa -1.66348
YBX1 Y box binding protein 1 -1.65909
DLEU1 deleted in lymphocytic leukemia 1 (non-protein coding) -1.65647
ZNF250 zinc finger protein 250 -1.65159
LAX1 lymphocyte transmembrane adaptor 1 -1.64864
ATP5O ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit -1.64383
FTSJ3 FtsJ homolog 3 (E. coli) -1.64062
PRKCE protein kinase C, epsilon -1.63899
SFTPC surfactant protein C -1.6363
RPAIN RPA interacting protein -1.63277
MPC2 mitochondrial pyruvate carrier 2 -1.62624
SUCLA2 succinate-CoA ligase, ADP-forming, beta subunit -1.60379
ARL6IP5 ADP-ribosylation factor-like 6 interacting protein 5 -1.60285
FMO6P flavin containing monooxygenase 6 pseudogene -1.59486
IPO5 importin 5 -1.58814
REV3L REV3-like, polymerase (DNA directed), zeta, catalytic subunit -1.57723
TCP1 t-complex 1 -1.57074
UCHL5 ubiquitin carboxyl-terminal hydrolase L5 -1.56831
PIGP phosphatidylinositol glycan anchor biosynthesis, class P -1.55681
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -1.55608
NDC1 NDC1 transmembrane nucleoporin -1.54764
ACTR2 ARP2 actin-related protein 2 homolog (yeast) -1.5465
MYT1 myelin transcription factor 1 -1.54503
TLR6 toll-like receptor 6 -1.54268
NTRK3 neurotrophic tyrosine kinase, receptor, type 3 -1.53598
DCLRE1A DNA cross-link repair 1A -1.52898
ABHD5 abhydrolase domain containing 5 -1.52447
TMCO3 transmembrane and coiled-coil domains 3 -1.51377
UFC1 ubiquitin-fold modifier conjugating enzyme 1 -1.50617
FAM86C1 family with sequence similarity 86, member C1 -1.50184
NARS2 asparaginyl-tRNA synthetase 2, mitochondrial (putative) -1.49626
GNL2 guanine nucleotide binding protein-like 2 (nucleolar) -1.49174
KLHL12 kelch-like family member 12 -1.48761
RMDN1 regulator of microtubule dynamics 1 -1.48159
RINT1 RAD50 interactor 1 -1.47886
IRS4 insulin receptor substrate 4 -1.4766
SLC12A6 solute carrier family 12 (potassium/chloride transporter), member 6 -1.47396
UCK2 uridine-cytidine kinase 2 -1.4715
NDUFB1 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 1, 7kDa -1.46049
MRPS7 mitochondrial ribosomal protein S7 -1.45958
NRBF2 nuclear receptor binding factor 2 -1.45845
CHEK2 checkpoint kinase 2 -1.45614
HIST3H2A histone cluster 3, H2a -1.45558
DCP1A decapping mRNA 1A -1.45148
GTF3C3 general transcription factor IIIC, polypeptide 3, 102kDa -1.45076
UBL3 ubiquitin-like 3 -1.44982
CLASP2 cytoplasmic linker associated protein 2 -1.44939
HDDC2 HD domain containing 2 -1.44775
RBM12 RNA binding motif protein 12 -1.44538
ATP5J ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6 -1.44158
PWP2 PWP2 periodic tryptophan protein homolog (yeast) -1.44015
FCN2 ficolin (collagen/fibrinogen domain containing lectin) 2 -1.43733
SYNJ1 synaptojanin 1 -1.43434
UBE2V2 ubiquitin-conjugating enzyme E2 variant 2 -1.43353
CYB5R4 cytochrome b5 reductase 4 -1.4332
CDK8 cyclin-dependent kinase 8 -1.42454
PMS1 PMS1 postmeiotic segregation increased 1 (S. cerevisiae) -1.42333
RAD50 RAD50 homolog (S. cerevisiae) -1.42081
ZNF124 zinc finger protein 124 -1.41755