| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | calcium/calmodulin-dependent protein kinase II alpha|The product of this gene belongs to the serine/threonine protein kinases family, and to the Ca(2+)/calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM)-dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Nov 2008] (NCBI Entrez Gene Database, 815) |
| External Link | https://ncbi.nlm.nih.gov/gene/815 |
| Similar Terms | |
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498 genes differentially expressed following the CAMK2A gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | 0.0281187 |
| S100A8 | S100 calcium binding protein A8 | 0.0155428 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | 0.0151761 |
| MAP7 | microtubule-associated protein 7 | 0.01476 |
| HOPX | HOP homeobox | 0.0144368 |
| IPO13 | importin 13 | 0.0141246 |
| CYB5A | cytochrome b5 type A (microsomal) | 0.0134847 |
| SLPI | secretory leukocyte peptidase inhibitor | 0.0126884 |
| CRYAB | crystallin, alpha B | 0.0124771 |
| CTSD | cathepsin D | 0.012289 |
| MALL | mal, T-cell differentiation protein-like | 0.0122527 |
| FN1 | fibronectin 1 | 0.0120563 |
| PERP | PERP, TP53 apoptosis effector | 0.0119584 |
| CST6 | cystatin E/M | 0.0119442 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0112081 |
| GJA1 | gap junction protein, alpha 1, 43kDa | 0.0111517 |
| KLK5 | kallikrein-related peptidase 5 | 0.0111391 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.010986 |
| PPL | periplakin | 0.0108876 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C | 0.0104555 |
| PTK2B | protein tyrosine kinase 2 beta | 0.0104435 |
| CSTA | cystatin A (stefin A) | 0.0104008 |
| TPD52L1 | tumor protein D52-like 1 | 0.0103173 |
| QPCT | glutaminyl-peptide cyclotransferase | 0.0102896 |
| KRT14 | keratin 14, type I | 0.0102309 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | 0.0101968 |
| HSPA1A | heat shock 70kDa protein 1A | 0.0100805 |
| RNF128 | ring finger protein 128, E3 ubiquitin protein ligase | 0.00964721 |
| NVL | nuclear VCP-like | 0.0095817 |
| TARP | TCR gamma alternate reading frame protein | 0.00943722 |
| PLAAT3 | phospholipase A and acyltransferase 3 | 0.00928875 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | 0.00921865 |
| TPSAB1 | tryptase alpha/beta 1 | 0.00915344 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | 0.00901448 |
| SCEL | sciellin | 0.0089867 |
| SPINK2 | serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) | 0.00896551 |
| CA12 | carbonic anhydrase XII | 0.00883432 |
| AMDHD2 | amidohydrolase domain containing 2 | 0.00883038 |
| CRCT1 | cysteine-rich C-terminal 1 | 0.00867278 |
| VAMP8 | vesicle-associated membrane protein 8 | 0.00862505 |
| PRSS8 | protease, serine, 8 | 0.00860249 |
| S100A9 | S100 calcium binding protein A9 | 0.0085713 |
| KRT7 | keratin 7, type II | 0.00854771 |
| SULT1C2 | sulfotransferase family, cytosolic, 1C, member 2 | 0.00848726 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.00839618 |
| ECM1 | extracellular matrix protein 1 | 0.00837324 |
| RFTN1 | raftlin, lipid raft linker 1 | 0.00835338 |
| S100P | S100 calcium binding protein P | 0.0082914 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) | 0.00825769 |
| SLC1A1 | solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 | 0.00815215 |
| CALML5 | calmodulin-like 5 | 0.00799441 |
| CSTB | cystatin B (stefin B) | 0.00789842 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.00778423 |
| PLIN2 | perilipin 2 | 0.00775214 |
| KANK1 | KN motif and ankyrin repeat domains 1 | 0.00771693 |
| PLK2 | polo-like kinase 2 | 0.00771264 |
| KCNS3 | potassium voltage-gated channel, modifier subfamily S, member 3 | 0.0075991 |
| CKM | creatine kinase, muscle | 0.00753271 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | 0.00741751 |
| TNFRSF12A | tumor necrosis factor receptor superfamily, member 12A | 0.00741607 |
| AQP3 | aquaporin 3 (Gill blood group) | 0.00741539 |
| PLEKHM1 | pleckstrin homology domain containing, family M (with RUN domain) member 1 | 0.00740575 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | 0.00737394 |
| TRAPPC6A | trafficking protein particle complex 6A | 0.00736516 |
| ELANE | elastase, neutrophil expressed | 0.00729856 |
| MSMB | microseminoprotein, beta- | 0.00729827 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 | 0.00728948 |
| PAM16 | presequence translocase-associated motor 16 homolog (S. cerevisiae) | 0.00728851 |
| TTN | titin | 0.00726141 |
| RHOD | ras homolog family member D | 0.00725277 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.00723651 |
| CKS2 | CDC28 protein kinase regulatory subunit 2 | 0.00722458 |
| CNPY3 | canopy FGF signaling regulator 3 | 0.00718922 |
| COG7 | component of oligomeric golgi complex 7 | 0.00714003 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0071055 |
| EPHB6 | EPH receptor B6 | 0.00709765 |
| KLK7 | kallikrein-related peptidase 7 | 0.00706815 |
| SPINT2 | serine peptidase inhibitor, Kunitz type, 2 | 0.00698105 |
| HSPB8 | heat shock 22kDa protein 8 | 0.00691138 |
| TGFA | transforming growth factor, alpha | 0.00690952 |
| HTRA1 | HtrA serine peptidase 1 | 0.00686192 |
| FABP4 | fatty acid binding protein 4, adipocyte | 0.00685414 |
| CXCL13 | chemokine (C-X-C motif) ligand 13 | 0.00684779 |
| GALNT14 | polypeptide N-acetylgalactosaminyltransferase 14 | 0.00681197 |
| CENPU | centromere protein U | 0.00681023 |
| KRT16 | keratin 16, type I | 0.00680511 |
| CLIC3 | chloride intracellular channel 3 | 0.00674687 |
| CST7 | cystatin F (leukocystatin) | 0.00671844 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.0066912 |
| HACD1 | 3-hydroxyacyl-CoA dehydratase 1 | 0.0066865 |
| YBX3 | Y box binding protein 3 | 0.00668218 |
| ANXA4 | annexin A4 | 0.00667745 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | 0.00666071 |
| CASP8 | caspase 8, apoptosis-related cysteine peptidase | 0.00665966 |
| PON3 | paraoxonase 3 | 0.00665625 |
| HBD | hemoglobin, delta | 0.00664507 |
| KRT5 | keratin 5, type II | 0.00661725 |
| GALNT3 | polypeptide N-acetylgalactosaminyltransferase 3 | 0.00660583 |
| PIEZO1 | piezo-type mechanosensitive ion channel component 1 | 0.00658474 |
| NNMT | nicotinamide N-methyltransferase | 0.00658282 |
| PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 | 0.00645294 |
| S100A14 | S100 calcium binding protein A14 | 0.0064518 |
| RAB5IF | RAB5 interacting factor | 0.00644569 |
| LDOC1 | leucine zipper, down-regulated in cancer 1 | 0.00643411 |
| PRTN3 | proteinase 3 | 0.00642579 |
| RND3 | Rho family GTPase 3 | 0.00641384 |
| KRT6B | keratin 6B, type II | 0.00638606 |
| DEFA4 | defensin, alpha 4, corticostatin | 0.00638115 |
| ARPP19 | cAMP-regulated phosphoprotein, 19kDa | 0.00633957 |
| ADM | adrenomedullin | 0.00633301 |
| MEST | mesoderm specific transcript | 0.00631861 |
| PPARG | peroxisome proliferator-activated receptor gamma | 0.00629317 |
| ATP6V0E1 | ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1 | 0.00626652 |
| CNIH4 | cornichon family AMPA receptor auxiliary protein 4 | 0.00626323 |
| KLK10 | kallikrein-related peptidase 10 | 0.00623835 |
| BAMBI | BMP and activin membrane-bound inhibitor | 0.00623283 |
| ALDH3A2 | aldehyde dehydrogenase 3 family, member A2 | 0.00620949 |
| ABLIM1 | actin binding LIM protein 1 | 0.00620683 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) | 0.00620188 |
| TRIM16 | tripartite motif containing 16 | 0.00617757 |
| ATP2A1 | ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 | 0.00617691 |
| MLPH | melanophilin | 0.00614763 |
| SFTPA2 | surfactant protein A2 | 0.00614322 |
| ANXA3 | annexin A3 | 0.00612204 |
| SMPX | small muscle protein, X-linked | 0.00610742 |
| CXCL11 | chemokine (C-X-C motif) ligand 11 | 0.00609136 |
| LTF | lactotransferrin | 0.00608017 |
| CD46 | CD46 molecule, complement regulatory protein | 0.00606764 |
| MB | myoglobin | 0.00605491 |
| PTP4A1 | protein tyrosine phosphatase type IVA, member 1 | 0.00603188 |
| RHCG | Rh family, C glycoprotein | 0.00603049 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.00599233 |
| GPX3 | glutathione peroxidase 3 | 0.00597582 |
| FXYD3 | FXYD domain containing ion transport regulator 3 | 0.00597126 |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 | 0.00596855 |
| ZDHHC6 | zinc finger, DHHC-type containing 6 | 0.00595444 |
| JUP | junction plakoglobin | 0.00594987 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.00594454 |
| C1ORF116 | chromosome 1 open reading frame 116 | 0.00593966 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 | 0.00593304 |
| SWAP70 | SWAP switching B-cell complex 70kDa subunit | 0.00592862 |
| PSCA | prostate stem cell antigen | 0.00590863 |
| IL18 | interleukin 18 | 0.00590392 |
| MYLPF | myosin light chain, phosphorylatable, fast skeletal muscle | 0.00588493 |
| BAX | BCL2-associated X protein | 0.00588204 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.00586221 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 | 0.00584206 |
| MGRN1 | mahogunin ring finger 1, E3 ubiquitin protein ligase | 0.0058418 |
| SMPDL3A | sphingomyelin phosphodiesterase, acid-like 3A | 0.00582588 |
| NXN | nucleoredoxin | 0.00582555 |
| PDZK1IP1 | PDZK1 interacting protein 1 | 0.00582526 |
| ACOT13 | acyl-CoA thioesterase 13 | 0.00582259 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 | 0.00581207 |
| CALML3 | calmodulin-like 3 | 0.00579986 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.00578352 |
| OAZ3 | ornithine decarboxylase antizyme 3 | 0.00576615 |
| FGG | fibrinogen gamma chain | 0.00574992 |
| DSG1 | desmoglein 1 | 0.0057476 |
| SDC1 | syndecan 1 | 0.00573269 |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) | 0.00572473 |
| RAP1GAP2 | RAP1 GTPase activating protein 2 | 0.00568971 |
| MYO6 | myosin VI | 0.00568836 |
| IVL | involucrin | 0.00567484 |
| ACOT9 | acyl-CoA thioesterase 9 | 0.00567063 |
| IGLL1 | immunoglobulin lambda-like polypeptide 1 | 0.00564362 |
| NDUFA4L2 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2 | 0.00564233 |
| CST1 | cystatin SN | 0.00563311 |
| SFTPD | surfactant protein D | 0.00562715 |
| NKG7 | natural killer cell granule protein 7 | 0.00561502 |
| RBM47 | RNA binding motif protein 47 | 0.00558448 |
| WWC1 | WW and C2 domain containing 1 | 0.00556295 |
| PYCARD | PYD and CARD domain containing | 0.00556038 |
| KRT6A | keratin 6A, type II | 0.00555371 |
| GPNMB | glycoprotein (transmembrane) nmb | 0.00554488 |
| MET | MET proto-oncogene, receptor tyrosine kinase | 0.00552116 |
| RPS27L | ribosomal protein S27-like | 0.00549148 |
| HPGDS | hematopoietic prostaglandin D synthase | 0.00548501 |
| CD79B | CD79b molecule, immunoglobulin-associated beta | 0.00546698 |
| APOD | apolipoprotein D | 0.00545207 |
| EXT1 | exostosin glycosyltransferase 1 | 0.00544832 |
| SLC38A1 | solute carrier family 38, member 1 | 0.0054433 |
| MYBPC2 | myosin binding protein C, fast type | 0.00544191 |
| C10ORF10 | chromosome 10 open reading frame 10 | 0.00542193 |
| SFTPB | surfactant protein B | 0.00541914 |
| EAF2 | ELL associated factor 2 | 0.00540008 |
| AHR | aryl hydrocarbon receptor | 0.00539366 |
| AMOTL2 | angiomotin like 2 | 0.00539253 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.00537185 |
| PIK3CA | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha | 0.00536196 |
| AMH | anti-Mullerian hormone | 0.00535722 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.00533889 |
| CD9 | CD9 molecule | 0.0053333 |
| SFTPC | surfactant protein C | 0.00532602 |
| CA2 | carbonic anhydrase II | 0.00531564 |
| TPM4 | tropomyosin 4 | 0.00530083 |
| BCL2A1 | BCL2-related protein A1 | 0.00529628 |
| GGT1 | gamma-glutamyltransferase 1 | 0.00529292 |
| RAB32 | RAB32, member RAS oncogene family | 0.00529045 |
| SLC18A1 | solute carrier family 18 (vesicular monoamine transporter), member 1 | 0.00528512 |
| KRT17 | keratin 17, type I | 0.00528115 |
| TNNI1 | troponin I type 1 (skeletal, slow) | 0.00527108 |
| RAB25 | RAB25, member RAS oncogene family | 0.00525042 |
| MMP7 | matrix metallopeptidase 7 | 0.00524984 |
| SOCS2 | suppressor of cytokine signaling 2 | 0.00522702 |
| HMOX2 | heme oxygenase 2 | 0.00522192 |
| PCLAF | PCNA clamp associated factor | 0.0052117 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0051969 |
| RRAGD | Ras-related GTP binding D | 0.00519316 |
| HIST1H2AC | histone cluster 1, H2ac | 0.00519243 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0051882 |
| ZNF750 | zinc finger protein 750 | 0.00518807 |
| CTSH | cathepsin H | 0.0051859 |
| CCNG2 | cyclin G2 | 0.00518017 |
| P3H2 | prolyl 3-hydroxylase 2 | 0.00516931 |
| TM7SF3 | transmembrane 7 superfamily member 3 | 0.00516922 |
| CHI3L2 | chitinase 3-like 2 | 0.00514923 |
| KRT15 | keratin 15, type I | 0.00514606 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | 0.00514248 |
| CR2 | complement component (3d/Epstein Barr virus) receptor 2 | 0.0051342 |
| FXYD2 | FXYD domain containing ion transport regulator 2 | 0.00513386 |
| DSP | desmoplakin | 0.00512518 |
| SGK1 | serum/glucocorticoid regulated kinase 1 | 0.00511715 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.0051134 |
| SCGB1D2 | secretoglobin, family 1D, member 2 | 0.00511332 |
| TGM1 | transglutaminase 1 | 0.00511022 |
| MYOT | myotilin | 0.00509998 |
| BCL2L13 | BCL2-like 13 (apoptosis facilitator) | 0.00509716 |
| TNNI2 | troponin I type 2 (skeletal, fast) | 0.0050847 |
| GLYR1 | glyoxylate reductase 1 homolog (Arabidopsis) | 0.00508442 |
| TSC22D1 | TSC22 domain family, member 1 | 0.00507007 |
| MPHOSPH8 | M-phase phosphoprotein 8 | 0.00506837 |
| HTATIP2 | HIV-1 Tat interactive protein 2, 30kDa | 0.00504139 |
| CLDN4 | claudin 4 | 0.00503747 |
| RIPK4 | receptor-interacting serine-threonine kinase 4 | 0.00503424 |
| LRRC1 | leucine rich repeat containing 1 | 0.00503034 |
| SLC17A5 | solute carrier family 17 (acidic sugar transporter), member 5 | 0.00499854 |
| ME1 | malic enzyme 1, NADP(+)-dependent, cytosolic | 0.00499647 |
| ACTA1 | actin, alpha 1, skeletal muscle | 0.00498798 |
| LAT2 | linker for activation of T cells family, member 2 | 0.00498583 |
| FUT1 | fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) | 0.00498088 |
| GLO1 | glyoxalase I | 0.00497454 |
| CEACAM8 | carcinoembryonic antigen-related cell adhesion molecule 8 | 0.00497168 |
| MREG | melanoregulin | 0.00496491 |
| CD19 | CD19 molecule | 0.00495818 |
| PHLDA2 | pleckstrin homology-like domain, family A, member 2 | 0.00495727 |
| CTBP2 | C-terminal binding protein 2 | 0.0049466 |
| MYL2 | myosin, light chain 2, regulatory, cardiac, slow | 0.00494489 |
| CAV2 | caveolin 2 | 0.00494231 |
| LSR | lipolysis stimulated lipoprotein receptor | 0.00492471 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NLGN4X | neuroligin 4, X-linked | -0.0116044 |
| PLAT | plasminogen activator, tissue | -0.0114997 |
| SEPP1 | selenoprotein P, plasma, 1 | -0.0107774 |
| PRDX2 | peroxiredoxin 2 | -0.0100049 |
| DLK1 | delta-like 1 homolog (Drosophila) | -0.00970076 |
| MAP2K6 | mitogen-activated protein kinase kinase 6 | -0.00965711 |
| OLFM1 | olfactomedin 1 | -0.00959627 |
| ARHGEF40 | Rho guanine nucleotide exchange factor (GEF) 40 | -0.00955382 |
| TFF3 | trefoil factor 3 (intestinal) | -0.00946287 |
| KDM5D | lysine (K)-specific demethylase 5D | -0.00920524 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 | -0.00917874 |
| FCGBP | Fc fragment of IgG binding protein | -0.00897185 |
| F13A1 | coagulation factor XIII, A1 polypeptide | -0.00892196 |
| ARID4A | AT rich interactive domain 4A (RBP1-like) | -0.00890672 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.00878537 |
| TPBG | trophoblast glycoprotein | -0.00875336 |
| PDZD2 | PDZ domain containing 2 | -0.0087272 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.00871645 |
| PRKCA | protein kinase C, alpha | -0.00870883 |
| PEG3 | paternally expressed 3 | -0.00860317 |
| PLTP | phospholipid transfer protein | -0.00857917 |
| MPPED2 | metallophosphoesterase domain containing 2 | -0.0085722 |
| GOLGA8A | golgin A8 family, member A | -0.00855813 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.00854634 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.00844318 |
| PCOLCE | procollagen C-endopeptidase enhancer | -0.00839994 |
| LRRN3 | leucine rich repeat neuronal 3 | -0.00831367 |
| UCP2 | uncoupling protein 2 (mitochondrial, proton carrier) | -0.00831255 |
| NID1 | nidogen 1 | -0.00830531 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | -0.00829587 |
| TMEM176B | transmembrane protein 176B | -0.00819265 |
| MAGEA3 | melanoma antigen family A3 | -0.00813345 |
| METTL7A | methyltransferase like 7A | -0.0078745 |
| EPHB2 | EPH receptor B2 | -0.00782674 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | -0.00779105 |
| XPO7 | exportin 7 | -0.00772287 |
| GPC3 | glypican 3 | -0.00769628 |
| GPM6A | glycoprotein M6A | -0.00768302 |
| KCNJ2 | potassium channel, inwardly rectifying subfamily J, member 2 | -0.00766242 |
| MAN1C1 | mannosidase, alpha, class 1C, member 1 | -0.00765027 |
| PCDH9 | protocadherin 9 | -0.0076341 |
| NAP1L3 | nucleosome assembly protein 1-like 3 | -0.00754893 |
| SDC2 | syndecan 2 | -0.00746477 |
| NCAM1 | neural cell adhesion molecule 1 | -0.00740132 |
| CD302 | CD302 molecule | -0.00740086 |
| DACT1 | dishevelled-binding antagonist of beta-catenin 1 | -0.00736165 |
| DCXR | dicarbonyl/L-xylulose reductase | -0.00736007 |
| STC1 | stanniocalcin 1 | -0.00733979 |
| GATM | glycine amidinotransferase (L-arginine:glycine amidinotransferase) | -0.00729137 |
| MSX1 | msh homeobox 1 | -0.0072752 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.00725354 |
| ZIC1 | Zic family member 1 | -0.00721105 |
| NELL2 | NEL-like 2 (chicken) | -0.00719992 |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 | -0.0071929 |
| NES | nestin | -0.00716059 |
| ACKR3 | atypical chemokine receptor 3 | -0.00715786 |
| KANK2 | KN motif and ankyrin repeat domains 2 | -0.00711849 |
| MFHAS1 | malignant fibrous histiocytoma amplified sequence 1 | -0.00711462 |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta | -0.00707185 |
| MUC16 | mucin 16, cell surface associated | -0.00705931 |
| MAB21L2 | mab-21-like 2 (C. elegans) | -0.00703386 |
| FGL2 | fibrinogen-like 2 | -0.00698349 |
| REG3A | regenerating islet-derived 3 alpha | -0.00696861 |
| SELENBP1 | selenium binding protein 1 | -0.00696627 |
| CLCA1 | chloride channel accessory 1 | -0.0069364 |
| PSRC1 | proline/serine-rich coiled-coil 1 | -0.00692387 |
| DACH1 | dachshund family transcription factor 1 | -0.00691792 |
| CPQ | carboxypeptidase Q | -0.00689736 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.00686556 |
| COL4A5 | collagen, type IV, alpha 5 | -0.00686442 |
| CDC20 | cell division cycle 20 | -0.00684201 |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 | -0.00683852 |
| MEIS1 | Meis homeobox 1 | -0.0068037 |
| RELN | reelin | -0.00676595 |
| POGLUT2 | protein O-glucosyltransferase 2 | -0.00676249 |
| CNTN1 | contactin 1 | -0.0067575 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.00675102 |
| SYNGR3 | synaptogyrin 3 | -0.00673115 |
| OLFM4 | olfactomedin 4 | -0.00671449 |
| CD14 | CD14 molecule | -0.00665785 |
| COL15A1 | collagen, type XV, alpha 1 | -0.00662824 |
| MS4A6A | membrane-spanning 4-domains, subfamily A, member 6A | -0.00662081 |
| C14ORF132 | chromosome 14 open reading frame 132 | -0.00660952 |
| PBX1 | pre-B-cell leukemia homeobox 1 | -0.00659864 |
| WLS | wntless Wnt ligand secretion mediator | -0.0065892 |
| CST3 | cystatin C | -0.00658 |
| FABP1 | fatty acid binding protein 1, liver | -0.00657843 |
| NEFH | neurofilament, heavy polypeptide | -0.00657506 |
| COL6A1 | collagen, type VI, alpha 1 | -0.00654625 |
| HOXC6 | homeobox C6 | -0.00653842 |
| CDO1 | cysteine dioxygenase type 1 | -0.00648115 |
| PTPN2 | protein tyrosine phosphatase, non-receptor type 2 | -0.00646911 |
| COL14A1 | collagen, type XIV, alpha 1 | -0.00646408 |
| DDX11 | DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 | -0.00645192 |
| TMEM176A | transmembrane protein 176A | -0.00645165 |
| ASRGL1 | asparaginase like 1 | -0.00643355 |
| MECOM | MDS1 and EVI1 complex locus | -0.00642678 |
| GLG1 | golgi glycoprotein 1 | -0.00640049 |
| RESF1 | retroelement silencing factor 1 | -0.00639361 |
| B3GNT1 | -0.00638627 | |
| CTSZ | cathepsin Z | -0.00638529 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -0.00637572 |
| CD4 | CD4 molecule | -0.00637548 |
| PENK | proenkephalin | -0.00634058 |
| DDHD2 | DDHD domain containing 2 | -0.00633329 |
| ZNF423 | zinc finger protein 423 | -0.00632531 |
| HNMT | histamine N-methyltransferase | -0.00631164 |
| GPM6B | glycoprotein M6B | -0.00630656 |
| FGFR3 | fibroblast growth factor receptor 3 | -0.00625682 |
| RTN1 | reticulon 1 | -0.00625675 |
| CCR1 | chemokine (C-C motif) receptor 1 | -0.00625063 |
| SCD5 | stearoyl-CoA desaturase 5 | -0.00622692 |
| PTCH1 | patched 1 | -0.00621414 |
| DEFA5 | defensin, alpha 5, Paneth cell-specific | -0.00620767 |
| CLU | clusterin | -0.00620321 |
| PER2 | period circadian clock 2 | -0.00619935 |
| GLT8D2 | glycosyltransferase 8 domain containing 2 | -0.00619002 |
| SYBU | syntabulin (syntaxin-interacting) | -0.00617788 |
| MAGEA12 | melanoma antigen family A12 | -0.00617471 |
| CD209 | CD209 molecule | -0.00616913 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.00616497 |
| C1R | complement component 1, r subcomponent | -0.00615578 |
| SLC35G2 | solute carrier family 35, member G2 | -0.00614881 |
| PDGFRL | platelet-derived growth factor receptor-like | -0.00614403 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.00613742 |
| PIPOX | pipecolic acid oxidase | -0.00612765 |
| STMN2 | stathmin 2 | -0.00608341 |
| SPON1 | spondin 1, extracellular matrix protein | -0.00605968 |
| ZC2HC1A | zinc finger, C2HC-type containing 1A | -0.00603408 |
| BRD2 | bromodomain containing 2 | -0.00600947 |
| PCGF2 | polycomb group ring finger 2 | -0.00599989 |
| CNR1 | cannabinoid receptor 1 (brain) | -0.00598386 |
| UBE2E3 | ubiquitin-conjugating enzyme E2E 3 | -0.00597196 |
| TNFRSF1B | tumor necrosis factor receptor superfamily, member 1B | -0.00596683 |
| IQGAP2 | IQ motif containing GTPase activating protein 2 | -0.00595811 |
| TMEM47 | transmembrane protein 47 | -0.00595426 |
| DMD | dystrophin | -0.00594268 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.00592711 |
| CRYBG3 | beta-gamma crystallin domain containing 3 | -0.00592691 |
| NTS | neurotensin | -0.00590991 |
| HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 | -0.0058846 |
| CERK | ceramide kinase | -0.00588279 |
| LRIG1 | leucine-rich repeats and immunoglobulin-like domains 1 | -0.00587924 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.00585384 |
| DIXDC1 | DIX domain containing 1 | -0.00583649 |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 | -0.00582268 |
| CFH | complement factor H | -0.00580423 |
| CFI | complement factor I | -0.0057914 |
| PID1 | phosphotyrosine interaction domain containing 1 | -0.00577942 |
| SYT11 | synaptotagmin XI | -0.00575646 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | -0.00575161 |
| INSR | insulin receptor | -0.00574859 |
| DHRS11 | dehydrogenase/reductase (SDR family) member 11 | -0.00574498 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) | -0.00573508 |
| TMEM35 | transmembrane protein 35 | -0.00573274 |
| AKR7A2 | aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) | -0.00573011 |
| HOXA5 | homeobox A5 | -0.00571056 |
| CES1 | carboxylesterase 1 | -0.00570097 |
| CPNE1 | copine I | -0.00568535 |
| TAB2 | TGF-beta activated kinase 1/MAP3K7 binding protein 2 | -0.00567518 |
| DPYD | dihydropyrimidine dehydrogenase | -0.00567404 |
| TBC1D1 | TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1 | -0.00566656 |
| CSF1R | colony stimulating factor 1 receptor | -0.00566364 |
| KCND3 | potassium channel, voltage gated Shal related subfamily D, member 3 | -0.00566093 |
| HCLS1 | hematopoietic cell-specific Lyn substrate 1 | -0.00565563 |
| FEZ1 | fasciculation and elongation protein zeta 1 (zygin I) | -0.00565399 |
| TADA2A | transcriptional adaptor 2A | -0.00563725 |
| MCF2L | MCF.2 cell line derived transforming sequence-like | -0.00563577 |
| GRIA2 | glutamate receptor, ionotropic, AMPA 2 | -0.00562786 |
| FZD3 | frizzled class receptor 3 | -0.00562507 |
| ELOVL2 | ELOVL fatty acid elongase 2 | -0.00561248 |
| CCL4 | chemokine (C-C motif) ligand 4 | -0.00560494 |
| LEPR | leptin receptor | -0.00559696 |
| COL18A1 | collagen, type XVIII, alpha 1 | -0.00559487 |
| NDP | Norrie disease (pseudoglioma) | -0.00559352 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.00558652 |
| ITIH2 | inter-alpha-trypsin inhibitor heavy chain 2 | -0.00557673 |
| LAMA2 | laminin, alpha 2 | -0.00557408 |
| ZFHX4 | zinc finger homeobox 4 | -0.00554936 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.00554675 |
| STON1 | stonin 1 | -0.00554585 |
| IMPDH2 | IMP (inosine 5'-monophosphate) dehydrogenase 2 | -0.00554273 |
| CH25H | cholesterol 25-hydroxylase | -0.00552658 |
| CPVL | carboxypeptidase, vitellogenic-like | -0.00551748 |
| ANO1 | anoctamin 1, calcium activated chloride channel | -0.00551573 |
| IL17RB | interleukin 17 receptor B | -0.00551121 |
| TWIST1 | twist family bHLH transcription factor 1 | -0.00550734 |
| APOC2 | apolipoprotein C-II | -0.00550631 |
| PPP2R1B | protein phosphatase 2, regulatory subunit A, beta | -0.00549639 |
| FLOT2 | flotillin 2 | -0.00547752 |
| GAS1 | growth arrest-specific 1 | -0.00547293 |
| LRP1 | low density lipoprotein receptor-related protein 1 | -0.00546641 |
| TXLNA | taxilin alpha | -0.00546267 |
| ADCY7 | adenylate cyclase 7 | -0.00545473 |
| PLAGL2 | pleiomorphic adenoma gene-like 2 | -0.00542397 |
| BEX1 | brain expressed, X-linked 1 | -0.0054204 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.00540784 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.00540597 |
| QPRT | quinolinate phosphoribosyltransferase | -0.00538656 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.00537657 |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha | -0.00536931 |
| SNAP25 | synaptosomal-associated protein, 25kDa | -0.00536816 |
| IQCG | IQ motif containing G | -0.00535739 |
| SLA | Src-like-adaptor | -0.00535234 |
| TRMT5 | tRNA methyltransferase 5 | -0.00534865 |
| HIC2 | hypermethylated in cancer 2 | -0.00532522 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | -0.00532032 |
| LEFTY1 | left-right determination factor 1 | -0.00531724 |
| CHCHD7 | coiled-coil-helix-coiled-coil-helix domain containing 7 | -0.00531615 |
| REG1B | regenerating islet-derived 1 beta | -0.00531438 |
| C8ORF4 | chromosome 8 open reading frame 4 | -0.00530528 |
| MAP1B | microtubule-associated protein 1B | -0.00530161 |
| CCNF | cyclin F | -0.00529446 |
| NBPF10 | neuroblastoma breakpoint family, member 10 | -0.0052851 |
| CEP170 | centrosomal protein 170kDa | -0.00527845 |
| CCDC176 | coiled-coil domain containing 176 | -0.00527346 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.00526682 |
| C1QTNF3 | C1q and tumor necrosis factor related protein 3 | -0.00526101 |
| DEFA6 | defensin, alpha 6, Paneth cell-specific | -0.00526095 |
| SHOX2 | short stature homeobox 2 | -0.00525964 |
| FOXF1 | forkhead box F1 | -0.00525761 |
| DNAJC6 | DnaJ (Hsp40) homolog, subfamily C, member 6 | -0.00524449 |
| NCOA3 | nuclear receptor coactivator 3 | -0.00524342 |
| CHN2 | chimerin 2 | -0.00522827 |
| ITM2A | integral membrane protein 2A | -0.0052188 |
| FAXDC2 | fatty acid hydroxylase domain containing 2 | -0.00521792 |
| GYG2 | glycogenin 2 | -0.00521077 |
| ZDHHC17 | zinc finger, DHHC-type containing 17 | -0.00520999 |
| FBLN1 | fibulin 1 | -0.0052095 |
| OGN | osteoglycin | -0.00519264 |
| TMEM231 | transmembrane protein 231 | -0.00518803 |
| BTBD3 | BTB (POZ) domain containing 3 | -0.00518431 |
| C4ORF19 | chromosome 4 open reading frame 19 | -0.00517489 |
| NASP | nuclear autoantigenic sperm protein (histone-binding) | -0.00516664 |
| GPR183 | G protein-coupled receptor 183 | -0.00516229 |
| GRAMD2B | GRAM domain containing 2B | -0.0051576 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | -0.00515755 |
| SOBP | sine oculis binding protein homolog (Drosophila) | -0.00515484 |
| CPD | carboxypeptidase D | -0.00514983 |
| SNRPD1 | small nuclear ribonucleoprotein D1 polypeptide 16kDa | -0.00514963 |
| ANKRD11 | ankyrin repeat domain 11 | -0.00514931 |
| NR3C2 | nuclear receptor subfamily 3, group C, member 2 | -0.00514546 |
| MYH11 | myosin, heavy chain 11, smooth muscle | -0.00513607 |
| SFRP1 | secreted frizzled-related protein 1 | -0.00513238 |
| TUBB3 | tubulin, beta 3 class III | -0.00512306 |
| WNT5A | wingless-type MMTV integration site family, member 5A | -0.00511188 |
| SMARCA1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 | -0.00511134 |
| CD163 | CD163 molecule | -0.00510954 |
| DEDD | death effector domain containing | -0.0051083 |
