CAMK2A Gene Set

Dataset PhosphoSitePlus Substrates of Kinases
Category physical interactions
Type kinase
Description calcium/calmodulin-dependent protein kinase II alpha|The product of this gene belongs to the serine/threonine protein kinases family, and to the Ca(2+)/calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM)-dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Nov 2008] (NCBI Entrez Gene Database, 815)
External Link http://www.ncbi.nlm.nih.gov/gene/815
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Genes

70 substrates of the kinase CAMK2A from the curated PhosphoSitePlus Substrates of Kinases dataset.

Symbol Name
ABI1 abl-interactor 1
ADCY3 adenylate cyclase 3
ALOX5 arachidonate 5-lipoxygenase
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit
CAMK2A calcium/calmodulin-dependent protein kinase II alpha
CARD11 caspase recruitment domain family, member 11
CD44 CD44 molecule (Indian blood group)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CHAT choline O-acetyltransferase
CLCN3 chloride channel, voltage-sensitive 3
CREM cAMP responsive element modulator
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
DLGAP1 discs, large (Drosophila) homolog-associated protein 1
DPYSL2 dihydropyrimidinase-like 2
ESPL1 extra spindle pole bodies homolog 1 (S. cerevisiae)
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
FBXO43 F-box protein 43
FLNA filamin A, alpha
FOSB FBJ murine osteosarcoma viral oncogene homolog B
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1
GFPT1 glutamine--fructose-6-phosphate transaminase 1
GJC1 gap junction protein, gamma 1, 45kDa
GLO1 glyoxalase I
GRIA1 glutamate receptor, ionotropic, AMPA 1
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B
HDAC5 histone deacetylase 5
HRH1 histamine receptor H1
HSF1 heat shock transcription factor 1
IL6ST interleukin 6 signal transducer
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITGB1BP1 integrin beta 1 binding protein 1
ITPKA inositol-trisphosphate 3-kinase A
KCNJ11 potassium channel, inwardly rectifying subfamily J, member 11
KIF17 kinesin family member 17
KIF3A kinesin family member 3A
MAPT microtubule-associated protein tau
MCU mitochondrial calcium uniporter
MYBPC3 myosin binding protein C, cardiac
NCOR2 nuclear receptor corepressor 2
NEFL neurofilament, light polypeptide
NLGN1 neuroligin 1
NOX5 NADPH oxidase, EF-hand calcium binding domain 5
NR1H2 nuclear receptor subfamily 1, group H, member 2
OPRM1 opioid receptor, mu 1
PDC phosducin
PEA15 phosphoprotein enriched in astrocytes 15
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLN phospholamban
PPP1R14A protein phosphatase 1, regulatory (inhibitor) subunit 14A
PTK2 protein tyrosine kinase 2
PTPRA protein tyrosine phosphatase, receptor type, A
RCHY1 ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase
RRAD Ras-related associated with diabetes
RYR2 ryanodine receptor 2 (cardiac)
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SLN sarcolipin
SMAD2 SMAD family member 2
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SPR sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)
SRF serum response factor (c-fos serum response element-binding transcription factor)
STMN1 stathmin 1
SYN1 synapsin I
TCAP titin-cap
TH tyrosine hydroxylase
TPH2 tryptophan hydroxylase 2
TRPC6 transient receptor potential cation channel, subfamily C, member 6
VIM vimentin
WEE2 WEE1 homolog 2 (S. pombe)