CAMP_UP.V1 Gene Set

Dataset MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations
Category transcriptomics
Type gene perturbation
Description gene perturbation identified as [gene symbol]_[perturbation or condition] (Molecular Signatures Database)
External Link http://www.broadinstitute.org/gsea/msigdb/cards/CAMP_UP.V1_UP
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Genes

396 genes differentially expressed following the CAMP_UP.V1 gene perturbation from the MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations dataset.

increased expression

Symbol Name
AAAS achalasia, adrenocortical insufficiency, alacrimia
AARS alanyl-tRNA synthetase
AATF apoptosis antagonizing transcription factor
ACO2 aconitase 2, mitochondrial
ACSL4 acyl-CoA synthetase long-chain family member 4
AHCYL1 adenosylhomocysteinase-like 1
AKAP6 A kinase (PRKA) anchor protein 6
ALAS1 5'-aminolevulinate synthase 1
ALDOA aldolase A, fructose-bisphosphate
ANKHD1-EIF4EBP3 ANKHD1-EIF4EBP3 readthrough
ANKRA2 ankyrin repeat, family A (RFXANK-like), 2
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C
ARF1 ADP-ribosylation factor 1
ATF4 activating transcription factor 4
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide
ATP5A1 ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle
ATP5B ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide
ATP5G2 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9)
ATXN7L3B ataxin 7-like 3B
AZIN1 antizyme inhibitor 1
BLCAP bladder cancer associated protein
BSCL2 Berardinelli-Seip congenital lipodystrophy 2 (seipin)
C11ORF71 chromosome 11 open reading frame 71
C14ORF159 chromosome 14 open reading frame 159
C1ORF123 chromosome 1 open reading frame 123
C21ORF33 chromosome 21 open reading frame 33
CCDC124 coiled-coil domain containing 124
CCL5 chemokine (C-C motif) ligand 5
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CEBPG CCAAT/enhancer binding protein (C/EBP), gamma
CEP250 centrosomal protein 250kDa
CEP41 centrosomal protein 41kDa
CHAF1A chromatin assembly factor 1, subunit A (p150)
CHST5 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5
CKMT1A creatine kinase, mitochondrial 1A
CLOCK clock circadian regulator
CLPTM1 cleft lip and palate associated transmembrane protein 1
CMTR1 cap methyltransferase 1
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family)
COG6 component of oligomeric golgi complex 6
COL6A3 collagen, type VI, alpha 3
COPE coatomer protein complex, subunit epsilon
COPZ1 coatomer protein complex, subunit zeta 1
COX8A cytochrome c oxidase subunit VIIIA (ubiquitous)
CPEB4 cytoplasmic polyadenylation element binding protein 4
CRABP1 cellular retinoic acid binding protein 1
CS citrate synthase
CXCL8 chemokine (C-X-C motif) ligand 8
CYBA cytochrome b-245, alpha polypeptide
DAP3 death associated protein 3
DDX23 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23
DIP2B DIP2 disco-interacting protein 2 homolog B (Drosophila)
DPAGT1 dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase)
DPM2 dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit
EARS2 glutamyl-tRNA synthetase 2, mitochondrial
ECSIT ECSIT signalling integrator
EIF2B3 eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa
ELMO1 engulfment and cell motility 1
ELN elastin
ETV5 ets variant 5
FAHD2A fumarylacetoacetate hydrolase domain containing 2A
FBXO42 F-box protein 42
FLOT1 flotillin 1
FOS FBJ murine osteosarcoma viral oncogene homolog
GAS5 growth arrest-specific 5 (non-protein coding)
GLRX glutaredoxin (thioltransferase)
GMPPA GDP-mannose pyrophosphorylase A
GPR160 G protein-coupled receptor 160
HAX1 HCLS1 associated protein X-1
HDLBP high density lipoprotein binding protein
HLA-DRB5 major histocompatibility complex, class II, DR beta 5
HMGB2 high mobility group box 2
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
HSPA9 heat shock 70kDa protein 9 (mortalin)
HSPBP1 HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IFITM1 interferon induced transmembrane protein 1
IFITM3 interferon induced transmembrane protein 3
IFRD1 interferon-related developmental regulator 1
ILF2 interleukin enhancer binding factor 2
IPO4 importin 4
IST1 increased sodium tolerance 1 homolog (yeast)
IVNS1ABP influenza virus NS1A binding protein
KANSL1 KAT8 regulatory NSL complex subunit 1
KANSL3 KAT8 regulatory NSL complex subunit 3
KAT5 K(lysine) acetyltransferase 5
KIAA0040 KIAA0040
KIAA0141 KIAA0141
KRTAP4-7 keratin associated protein 4-7
LETMD1 LETM1 domain containing 1
LIMS1 LIM and senescent cell antigen-like domains 1
LONP1 lon peptidase 1, mitochondrial
LRR1 leucine rich repeat protein 1
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast)
MAEA macrophage erythroblast attacher
MAGED1 melanoma antigen family D1
MAGOH mago-nashi homolog, proliferation-associated (Drosophila)
MARS methionyl-tRNA synthetase
MDH2 malate dehydrogenase 2, NAD (mitochondrial)
METTL17 methyltransferase like 17
MIDN midnolin
MRPL15 mitochondrial ribosomal protein L15
MRPS18A mitochondrial ribosomal protein S18A
MRRF mitochondrial ribosome recycling factor
MT2A metallothionein 2A
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
MYC v-myc avian myelocytomatosis viral oncogene homolog
NDEL1 nudE neurodevelopment protein 1-like 1
NDRG2 NDRG family member 2
NDUFB5 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa
NDUFS2 NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase)
NDUFV1 NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa
NFX1 nuclear transcription factor, X-box binding 1
NLRP1 NLR family, pyrin domain containing 1
NME1 NME/NM23 nucleoside diphosphate kinase 1
NQO2 NAD(P)H dehydrogenase, quinone 2
NRSN2 neurensin 2
NSUN3 NOP2/Sun domain family, member 3
NT5DC1 5'-nucleotidase domain containing 1
NUAK2 NUAK family, SNF1-like kinase, 2
OCIAD1 OCIA domain containing 1
OXA1L oxidase (cytochrome c) assembly 1-like
P4HB prolyl 4-hydroxylase, beta polypeptide
PA2G4 proliferation-associated 2G4, 38kDa
PCMTD1 protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1
PDE4DIP phosphodiesterase 4D interacting protein
PDIA3 protein disulfide isomerase family A, member 3
PEX12 peroxisomal biogenesis factor 12
PIGS phosphatidylinositol glycan anchor biosynthesis, class S
PLCH1 phospholipase C, eta 1
PLSCR1 phospholipid scramblase 1
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
POLR3H polymerase (RNA) III (DNA directed) polypeptide H (22.9kD)
PPIB peptidylprolyl isomerase B (cyclophilin B)
PPP1R15A protein phosphatase 1, regulatory subunit 15A
PRIM1 primase, DNA, polypeptide 1 (49kDa)
PRMT1 protein arginine methyltransferase 1
PXK PX domain containing serine/threonine kinase
PYCR2 pyrroline-5-carboxylate reductase family, member 2
RABGGTA Rab geranylgeranyltransferase, alpha subunit
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2
RBCK1 RanBP-type and C3HC4-type zinc finger containing 1
RCHY1 ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase
RHOT2 ras homolog family member T2
RNF41 ring finger protein 41, E3 ubiquitin protein ligase
RPL18A ribosomal protein L18a
RPN1 ribophorin I
RUVBL1 RuvB-like AAA ATPase 1
SAT2 spermidine/spermine N1-acetyltransferase family member 2
SCARB1 scavenger receptor class B, member 1
SDAD1 SDA1 domain containing 1
SEC13 SEC13 homolog (S. cerevisiae)
SEC61A1 Sec61 alpha 1 subunit (S. cerevisiae)
SELENBP1 selenium binding protein 1
SESN2 sestrin 2
SIL1 SIL1 nucleotide exchange factor
SLC22A17 solute carrier family 22, member 17
SLC25A11 solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11
SLC25A5 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5
SLC35A4 solute carrier family 35, member A4
SMYD5 SMYD family member 5
SNW1 SNW domain containing 1
SPOP speckle-type POZ protein
SRPK1 SRSF protein kinase 1
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma)
STAT4 signal transducer and activator of transcription 4
STRADA STE20-related kinase adaptor alpha
TAF1D TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa
TBC1D15 TBC1 domain family, member 15
TFPI2 tissue factor pathway inhibitor 2
TGFBI transforming growth factor, beta-induced, 68kDa
TMED9 transmembrane emp24 protein transport domain containing 9
TMEM116 transmembrane protein 116
TMEM9 transmembrane protein 9
TNIK TRAF2 and NCK interacting kinase
TOMM40L translocase of outer mitochondrial membrane 40 homolog (yeast)-like
TRIM2 tripartite motif containing 2
TRIM38 tripartite motif containing 38
TRMT61A tRNA methyltransferase 61A
TYMP thymidine phosphorylase
UFM1 ubiquitin-fold modifier 1
UPP1 uridine phosphorylase 1
URM1 ubiquitin related modifier 1
VAMP4 vesicle-associated membrane protein 4
VIMP VCP-interacting membrane selenoprotein
WAPAL wings apart-like homolog (Drosophila)
WASH3P WAS protein family homolog 3 pseudogene
WBP1 WW domain binding protein 1
WDR24 WD repeat domain 24
WIPI1 WD repeat domain, phosphoinositide interacting 1
WWP1 WW domain containing E3 ubiquitin protein ligase 1
XIST X inactive specific transcript (non-protein coding)
ZBED5 zinc finger, BED-type containing 5
ZDHHC23 zinc finger, DHHC-type containing 23
ZNF367 zinc finger protein 367
ZNF385A zinc finger protein 385A

decreased expression

Symbol Name
ABLIM1 actin binding LIM protein 1
ACAT2 acetyl-CoA acetyltransferase 2
AK5 adenylate kinase 5
AKAP12 A kinase (PRKA) anchor protein 12
AKT3 v-akt murine thymoma viral oncogene homolog 3
ANKRD6 ankyrin repeat domain 6
ANXA1 annexin A1
ARHGAP5 Rho GTPase activating protein 5
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12
ASAP2 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
ATL1 atlastin GTPase 1
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4
ATP8A1 ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1
ATP9A ATPase, class II, type 9A
BACE1 beta-site APP-cleaving enzyme 1
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2
BAG6 BCL2-associated athanogene 6
BCL2L13 BCL2-like 13 (apoptosis facilitator)
BCR breakpoint cluster region
BIRC3 baculoviral IAP repeat containing 3
BSN bassoon presynaptic cytomatrix protein
BZW1 basic leucine zipper and W2 domains 1
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CAMK2D calcium/calmodulin-dependent protein kinase II delta
CAPN12 calpain 12
CASP7 caspase 7, apoptosis-related cysteine peptidase
CCND2 cyclin D2
CCR9 chemokine (C-C motif) receptor 9
CD160 CD160 molecule
CD83 CD83 molecule
CDCA7L cell division cycle associated 7-like
CELF2 CUGBP, Elav-like family member 2
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2
CLK1 CDC-like kinase 1
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1)
DCAF6 DDB1 and CUL4 associated factor 6
DDAH1 dimethylarginine dimethylaminohydrolase 1
DEDD2 death effector domain containing 2
DGCR5 DiGeorge syndrome critical region gene 5 (non-protein coding)
DLG5 discs, large homolog 5 (Drosophila)
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1
DPYSL3 dihydropyrimidinase-like 3
DST dystonin
DYNLL1 dynein, light chain, LC8-type 1
EIF4B eukaryotic translation initiation factor 4B
EIF4E eukaryotic translation initiation factor 4E
ENO2 enolase 2 (gamma, neuronal)
EPB41L3 erythrocyte membrane protein band 4.1-like 3
ERC2 ELKS/RAB6-interacting/CAST family member 2
ESYT1 extended synaptotagmin-like protein 1
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
EZR ezrin
FAM134C family with sequence similarity 134, member C
FAM189B family with sequence similarity 189, member B
FOSB FBJ murine osteosarcoma viral oncogene homolog B
FOXN3 forkhead box N3
FRY furry homolog (Drosophila)
FSTL1 follistatin-like 1
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase)
GAL3ST3 galactose-3-O-sulfotransferase 3
GEM GTP binding protein overexpressed in skeletal muscle
GLO1 glyoxalase I
GLS glutaminase
GNAQ guanine nucleotide binding protein (G protein), q polypeptide
GNG12 guanine nucleotide binding protein (G protein), gamma 12
HENMT1 HEN1 methyltransferase homolog 1 (Arabidopsis)
HINT1 histidine triad nucleotide binding protein 1
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSPA1A heat shock 70kDa protein 1A
HSPA8 heat shock 70kDa protein 8
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
IDS iduronate 2-sulfatase
IGFBP5 insulin-like growth factor binding protein 5
IL4R interleukin 4 receptor
IL7R interleukin 7 receptor
INSIG1 insulin induced gene 1
IQCK IQ motif containing K
ITPA inosine triphosphatase (nucleoside triphosphate pyrophosphatase)
ITSN1 intersectin 1 (SH3 domain protein)
JARID2 jumonji, AT rich interactive domain 2
KBTBD11 kelch repeat and BTB (POZ) domain containing 11
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KLHDC4 kelch domain containing 4
LMBR1 limb development membrane protein 1
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
LTA lymphotoxin alpha
MAL2 mal, T-cell differentiation protein 2 (gene/pseudogene)
MAP2 microtubule-associated protein 2
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4
MAPK1 mitogen-activated protein kinase 1
MBD2 methyl-CpG binding domain protein 2
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MED4 mediator complex subunit 4
MFN1 mitofusin 1
MIR155HG MIR155 host gene
MPZL3 myelin protein zero-like 3
MS4A6A membrane-spanning 4-domains, subfamily A, member 6A
MTMR9 myotubularin related protein 9
MYH10 myosin, heavy chain 10, non-muscle
MYO15B myosin XVB
MYO5B myosin VB
NAP1L1 nucleosome assembly protein 1-like 1
NAP1L2 nucleosome assembly protein 1-like 2
NCF2 neutrophil cytosolic factor 2
NDRG1 N-myc downstream regulated 1
NDRG4 NDRG family member 4
NFATC2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NPEPPS aminopeptidase puromycin sensitive
NTM neurotrimin
NUDT11 nudix (nucleoside diphosphate linked moiety X)-type motif 11
NYNRIN NYN domain and retroviral integrase containing
OAT ornithine aminotransferase
P2RY10 purinergic receptor P2Y, G-protein coupled, 10
PAEP progestagen-associated endometrial protein
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3
PALLD palladin, cytoskeletal associated protein
PAM peptidylglycine alpha-amidating monooxygenase
PCLO piccolo presynaptic cytomatrix protein
PCYOX1L prenylcysteine oxidase 1 like
PELI1 pellino E3 ubiquitin protein ligase 1
PES1 pescadillo ribosomal biogenesis factor 1
PFKFB4 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
PGBD3 piggyBac transposable element derived 3
PHLDB1 pleckstrin homology-like domain, family B, member 1
PINK1 PTEN induced putative kinase 1
PKIA protein kinase (cAMP-dependent, catalytic) inhibitor alpha
PLEK pleckstrin
PLS3 plastin 3
PRDM1 PR domain containing 1, with ZNF domain
PRDM8 PR domain containing 8
PTBP3 polypyrimidine tract binding protein 3
PTPRC protein tyrosine phosphatase, receptor type, C
PTPRD protein tyrosine phosphatase, receptor type, D
RAB31 RAB31, member RAS oncogene family
RALGAPA1 Ral GTPase activating protein, alpha subunit 1 (catalytic)
RAP2A RAP2A, member of RAS oncogene family
RASD2 RASD family, member 2
RERE arginine-glutamic acid dipeptide (RE) repeats
RGS1 regulator of G-protein signaling 1
RGS18 regulator of G-protein signaling 18
RNF138 ring finger protein 138, E3 ubiquitin protein ligase
RPL7 ribosomal protein L7
RRAD Ras-related associated with diabetes
RWDD2B RWD domain containing 2B
SCG5 secretogranin V
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SEPT11 septin 11
SEPT7 septin 7
SERINC1 serine incorporator 1
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SH3PXD2A SH3 and PX domains 2A
SLC13A4 solute carrier family 13 (sodium/sulfate symporter), member 4
SLC15A2 solute carrier family 15 (oligopeptide transporter), member 2
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SLC35E2 solute carrier family 35, member E2
SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1
SNN stannin
SNRPA small nuclear ribonucleoprotein polypeptide A
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
SRRM1 serine/arginine repetitive matrix 1
SRSF2 serine/arginine-rich splicing factor 2
ST13 suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein)
STXBP1 syntaxin binding protein 1
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
SYPL1 synaptophysin-like 1
SYT11 synaptotagmin XI
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
TARBP1 TAR (HIV-1) RNA binding protein 1
THSD7A thrombospondin, type I, domain containing 7A
TIMP2 TIMP metallopeptidase inhibitor 2
TJP1 tight junction protein 1
TLN2 talin 2
TMBIM1 transmembrane BAX inhibitor motif containing 1
TMEM97 transmembrane protein 97
TMEM98 transmembrane protein 98
TMSB4X thymosin beta 4, X-linked
TRPC1 transient receptor potential cation channel, subfamily C, member 1
TSC22D1 TSC22 domain family, member 1
TSPAN5 tetraspanin 5
TTYH3 tweety family member 3
TUBA4A tubulin, alpha 4a
TUBB2B tubulin, beta 2B class IIb
TUBB3 tubulin, beta 3 class III
TUBB4B tubulin, beta 4B class IVb
UBE2E2 ubiquitin-conjugating enzyme E2E 2
UBE2QL1 ubiquitin-conjugating enzyme E2Q family-like 1
UBTD2 ubiquitin domain containing 2
UBTF upstream binding transcription factor, RNA polymerase I
UNC79 unc-79 homolog (C. elegans)
USP36 ubiquitin specific peptidase 36
USP38 ubiquitin specific peptidase 38
ZCCHC14 zinc finger, CCHC domain containing 14
ZFP36 ZFP36 ring finger protein
ZMIZ1 zinc finger, MIZ-type containing 1