CAND1 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description cullin-associated and neddylation-dissociated 1| (NCBI Entrez Gene Database, 55832)
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Genes

360 genes differentially expressed following the CAND1 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
ABCC9 ATP-binding cassette, sub-family C (CFTR/MRP), member 9 2.89167
DDO D-aspartate oxidase 2.89167
RRAD Ras-related associated with diabetes 2.89167
OR10A6 olfactory receptor, family 10, subfamily A, member 6 (gene/pseudogene) 2.89167
PAX2 paired box 2 2.89167
MYOM2 myomesin 2 2.89167
RFPL2 ret finger protein-like 2 2.89167
UBE2U ubiquitin-conjugating enzyme E2U (putative) 2.89167
CXCL2 chemokine (C-X-C motif) ligand 2 2.89167
NLRP10 NLR family, pyrin domain containing 10 2.89167
UMODL1 uromodulin-like 1 2.89167
SOX18 SRY (sex determining region Y)-box 18 2.89167
TNNI1 troponin I type 1 (skeletal, slow) 2.89167
EPPIN epididymal peptidase inhibitor 2.89167
AGTR1 angiotensin II receptor, type 1 2.89167
ROBO4 roundabout, axon guidance receptor, homolog 4 (Drosophila) 2.89167
BSND barttin CLCNK-type chloride channel accessory beta subunit 2.89167
CD14 CD14 molecule 2.89167
CELF6 CUGBP, Elav-like family member 6 2.89167
SPINK7 serine peptidase inhibitor, Kazal type 7 (putative) 2.89167
CABP4 calcium binding protein 4 2.89167
TXNDC8 thioredoxin domain containing 8 (spermatozoa) 2.89167
MAGEA4 melanoma antigen family A4 2.89167
OR1A1 olfactory receptor, family 1, subfamily A, member 1 2.89167
KCNE2 potassium channel, voltage gated subfamily E regulatory beta subunit 2 2.89167
MROH6 maestro heat-like repeat family member 6 2.89167
SLC10A5 solute carrier family 10, member 5 2.89167
NR4A2 nuclear receptor subfamily 4, group A, member 2 2.89167
CENPE centromere protein E, 312kDa 2.89167
FOLH1 folate hydrolase (prostate-specific membrane antigen) 1 2.89167
SGCA sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein) 2.89167
RNASE6 ribonuclease, RNase A family, k6 2.89167
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) 2.89167
SMCO3 single-pass membrane protein with coiled-coil domains 3 2.89167
NR2F2 nuclear receptor subfamily 2, group F, member 2 2.89167
ANKRD30A ankyrin repeat domain 30A 2.89167
GPAT2 glycerol-3-phosphate acyltransferase 2, mitochondrial 2.89167
SLC22A7 solute carrier family 22 (organic anion transporter), member 7 2.89167
MYL7 myosin, light chain 7, regulatory 2.89167
S100A1 S100 calcium binding protein A1 2.89167
GNRHR gonadotropin-releasing hormone receptor 2.89167
LIMD2 LIM domain containing 2 2.89167
TAS2R19 taste receptor, type 2, member 19 2.89167
BMP5 bone morphogenetic protein 5 2.89167
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) 2.89167
MYO16 myosin XVI 2.89167
MRC1 mannose receptor, C type 1 2.89167
ETV7 ets variant 7 2.89167
GSTT2 glutathione S-transferase theta 2 (gene/pseudogene) 2.89167
ICAM5 intercellular adhesion molecule 5, telencephalin 2.89167
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 2.89167
COXFA4L2 cytochrome c oxidase hypoxia associated subunit FA4L2 2.89167
SPATA46 spermatogenesis associated 46 2.89167
CABCOCO1 ciliary associated calcium binding coiled-coil 1 2.89167
RTL9 retrotransposon Gag like 9 2.89167
H1-6 H1.6 linker histone, cluster member 2.89167
ZNF728 zinc finger protein 728 2.89167
ZNF726 zinc finger protein 726 2.89167
SCEL sciellin 2.89167
ADGRG7 adhesion G protein-coupled receptor G7 2.89167
RCVRN recoverin 2.89167
ELOVL3 ELOVL fatty acid elongase 3 2.89167
SLC49A3 solute carrier family 49 member 3 2.89167
ODAD2 outer dynein arm docking complex subunit 2 2.89167
H2AC1 H2A clustered histone 1 2.89167
SPMIP9 sperm microtubule inner protein 9 2.89167
SPATA31H1 SPATA31 subfamily H member 1 2.89167
LY6S lymphocyte antigen 6 family member S 2.89167
PRR20G proline rich 20G 2.89167
KIF1C-AS1 KIF1C antisense RNA 1 2.89167
TMDD1 transmembrane and death domain 1 2.89167
SPMIP3 sperm microtubule inner protein 3 2.89167
MDFIC2 MyoD family inhibitor domain containing 2 2.89167
RHEX regulator of hemoglobinization and erythroid cell expansion 2.89167
MINDY4B MINDY family member 4B 2.89167
LMNTD2 lamin tail domain containing 2 2.89167
TMPRSS7 transmembrane protease, serine 7 2.89167
GOLGA7B golgin A7 family, member B 2.89167
MSX1 msh homeobox 1 2.89167
CATSPERD catsper channel auxiliary subunit delta 2.89167
PCDHB12 protocadherin beta 12 2.89167
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform 2.89167
FPR3 formyl peptide receptor 3 2.89167
KLHL35 kelch-like family member 35 2.89167
TSSK4 testis-specific serine kinase 4 2.89167
GPR75 G protein-coupled receptor 75 2.89167
SIX2 SIX homeobox 2 2.89167
C1ORF162 chromosome 1 open reading frame 162 2.89167
KLRF1 killer cell lectin-like receptor subfamily F, member 1 2.89167
KCNT1 potassium channel, sodium activated subfamily T, member 1 2.89167
XKR3 XK, Kell blood group complex subunit-related family, member 3 2.89167
CINP cyclin-dependent kinase 2 interacting protein 2.89167
SPATA22 spermatogenesis associated 22 2.89167
LY6H lymphocyte antigen 6 complex, locus H 2.89167
KL klotho 2.89167
SYT15 synaptotagmin XV 2.89167
SAMD11 sterile alpha motif domain containing 11 2.89167
SAA1 serum amyloid A1 2.89167
GJD2 gap junction protein, delta 2, 36kDa 2.89167
RASAL3 RAS protein activator like 3 2.89167
COX4I2 cytochrome c oxidase subunit IV isoform 2 (lung) 2.89167
LOXL4 lysyl oxidase-like 4 2.89167
OR56A3 olfactory receptor, family 56, subfamily A, member 3 2.89167
TRADD TNFRSF1A-associated via death domain 2.89167
SERINC4 serine incorporator 4 2.89167
SPINK9 serine peptidase inhibitor, Kazal type 9 2.89167
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2 2.89167
C2CD4B C2 calcium-dependent domain containing 4B 2.89167
LMOD3 leiomodin 3 (fetal) 2.89167
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1 2.89167
TEX19 testis expressed 19 2.89167
KIAA1210 KIAA1210 2.89167
KLK7 kallikrein-related peptidase 7 2.89167
FAM177B family with sequence similarity 177, member B 2.89167
SLC6A17 solute carrier family 6 (neutral amino acid transporter), member 17 2.89167
RAD51AP2 RAD51 associated protein 2 2.89167
UBQLNL ubiquilin-like 2.89167
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1 2.89167
CLRN1 clarin 1 2.89167
HSPA1L heat shock 70kDa protein 1-like 2.89167
GLOD5 glyoxalase domain containing 5 2.89167
NOX1 NADPH oxidase 1 2.89167
CAMK2A calcium/calmodulin-dependent protein kinase II alpha 2.89167
ERICH6B glutamate-rich 6B 2.89167
CALHM1 calcium homeostasis modulator 1 2.89167
ITGA10 integrin, alpha 10 2.89167
ANKRD53 ankyrin repeat domain 53 2.89167
ARHGAP40 Rho GTPase activating protein 40 2.89167
LAMB4 laminin, beta 4 2.89167
CNR2 cannabinoid receptor 2 (macrophage) 2.89167
FBXO15 F-box protein 15 2.89167
SYT8 synaptotagmin VIII 2.89167
GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type 2.89167
OR52N2 olfactory receptor, family 52, subfamily N, member 2 2.89167
OR52N4 olfactory receptor, family 52, subfamily N, member 4 (gene/pseudogene) 2.89167
NR1D1 nuclear receptor subfamily 1, group D, member 1 2.89167
NLRP14 NLR family, pyrin domain containing 14 2.89167
KCNA5 potassium channel, voltage gated shaker related subfamily A, member 5 2.89167
TRHR thyrotropin-releasing hormone receptor 2.89167
SMIM17 small integral membrane protein 17 2.89167
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled 2.89167
GSTA1 glutathione S-transferase alpha 1 2.89167
OTOP2 otopetrin 2 2.89167
CYTH4 cytohesin 4 2.89167
CLEC1A C-type lectin domain family 1, member A 2.89167
EFCC1 EF-hand and coiled-coil domain containing 1 2.89167
DEFB135 defensin, beta 135 2.89167
FOXF2 forkhead box F2 2.89167
ERVV-1 endogenous retrovirus group V, member 1 2.89167
BCL2A1 BCL2-related protein A1 2.89167
DES desmin 2.89167
DDX4 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 2.89167
PSORS1C1 psoriasis susceptibility 1 candidate 1 2.89167
NUTM2A NUT family member 2A 2.89167
MAEL maelstrom spermatogenic transposon silencer 2.89167
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor) 2.89167
ANKRD62 ankyrin repeat domain 62 2.89167
MAGEB17 melanoma antigen family B17 2.89167
COL11A2 collagen, type XI, alpha 2 2.89167
GH2 growth hormone 2 2.89167
MMP3 matrix metallopeptidase 3 2.89167
HHIPL2 HHIP-like 2 2.89167
CLNK cytokine-dependent hematopoietic cell linker 2.89167
ADAM20 ADAM metallopeptidase domain 20 2.89167
TGM5 transglutaminase 5 2.89167
ATP6V0D2 ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2 2.89167
CLCNKA chloride channel, voltage-sensitive Ka 2.89167
CYP3A43 cytochrome P450, family 3, subfamily A, polypeptide 43 2.89167
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle) 2.89167
CLCA1 chloride channel accessory 1 2.89167
GABRD gamma-aminobutyric acid (GABA) A receptor, delta 2.89167
PCDHGB5 protocadherin gamma subfamily B, 5 2.89167
FBXO39 F-box protein 39 2.89167
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1 2.89167
KRTAP5-11 keratin associated protein 5-11 2.89167
ABCG8 ATP-binding cassette, sub-family G (WHITE), member 8 2.89167
GAL3ST2 galactose-3-O-sulfotransferase 2 2.89167
KCNK4 potassium channel, two pore domain subfamily K, member 4 2.89167
EBF2 early B-cell factor 2 2.89167
RAB31 RAB31, member RAS oncogene family 2.85947
BSDC1 BSD domain containing 1 2.8504
TESMIN testis expressed metallothionein like protein 2.78894
MOB4 MOB family member 4, phocein 2.65918
FILIP1L filamin A interacting protein 1-like 2.58811
CYP27C1 cytochrome P450, family 27, subfamily C, polypeptide 1 2.58247
TIA1 TIA1 cytotoxic granule-associated RNA binding protein 2.57642
HINFP histone H4 transcription factor 2.57399
FTH1 ferritin, heavy polypeptide 1 2.55609
ACE angiotensin I converting enzyme 2.53148
TMTC3 transmembrane and tetratricopeptide repeat containing 3 2.52789
RAB5A RAB5A, member RAS oncogene family 2.49787
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2 2.4754
VPS13D vacuolar protein sorting 13 homolog D (S. cerevisiae) 2.47138
RTN2 reticulon 2 2.45924
ASGR2 asialoglycoprotein receptor 2 2.43347
SYCP1 synaptonemal complex protein 1 2.43347
H1-1 H1.1 linker histone, cluster member 2.39396
COX19 COX19 cytochrome c oxidase assembly factor 2.38187
ZNF358 zinc finger protein 358 2.37167
TP53INP2 tumor protein p53 inducible nuclear protein 2 2.36143
ANGPTL4 angiopoietin-like 4 2.35238
SRL sarcalumenin 2.34322
XCL1 chemokine (C motif) ligand 1 2.34322
KCNH8 potassium channel, voltage gated eag related subfamily H, member 8 2.3177
ZNF30 zinc finger protein 30 2.30256
CHN2 chimerin 2 2.29754
PCMTD1 protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1 2.2964
SERF2 small EDRK-rich factor 2 2.29208
RPL3 ribosomal protein L3 2.27965
LAMA5 laminin, alpha 5 2.27665
CCDC172 coiled-coil domain containing 172 2.27665
PTPRR protein tyrosine phosphatase, receptor type, R 2.27665
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1 2.27665
PPIA peptidylprolyl isomerase A (cyclophilin A) 2.27665
KIF1C kinesin family member 1C 2.25978
DYM dymeclin 2.24335
RACK1 receptor for activated C kinase 1 2.22649
DLGAP1 discs, large (Drosophila) homolog-associated protein 1 2.20193
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1) 2.18228
PCDH11X protocadherin 11 X-linked 2.17597
RALYL RALY RNA binding protein-like 2.17129
LYPLA2 lysophospholipase II 2.17076
DMRTA1 DMRT-like family A1 2.16577
FTL ferritin, light polypeptide 2.16577
NDUFB3 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa 2.13485
DAGLA diacylglycerol lipase, alpha 2.12338
DYSF dysferlin 2.12323
CCNB2 cyclin B2 2.12323
FDFT1 farnesyl-diphosphate farnesyltransferase 1 2.11094
CISD3 CDGSH iron sulfur domain 3 2.11094
DENND3 DENN/MADD domain containing 3 2.11094
ATG4C autophagy related 4C, cysteine peptidase 2.09787
DOCK7 dedicator of cytokinesis 7 2.09583
COPB2 coatomer protein complex, subunit beta 2 (beta prime) 2.09523
MPST mercaptopyruvate sulfurtransferase 2.08926
PNPT1 polyribonucleotide nucleotidyltransferase 1 2.08926
DEPTOR DEP domain containing MTOR-interacting protein 2.07519
DOK4 docking protein 4 2.07512
NELL2 NEL-like 2 (chicken) 2.0706
TNRC6C trinucleotide repeat containing 6C 2.06952
LRRC4B leucine rich repeat containing 4B 2.06766
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2 2.06391
RPS25 ribosomal protein S25 2.05595
WDR25 WD repeat domain 25 2.03992
SPCS2 signal peptidase complex subunit 2 homolog (S. cerevisiae) 2.00722

decreased expression

Symbol Name Standardized Value
BCAN brevican -2.89167
MICALL2 MICAL-like 2 -2.89167
CRTC2 CREB regulated transcription coactivator 2 -2.89167
WDSUB1 WD repeat, sterile alpha motif and U-box domain containing 1 -2.89167
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2 -2.89167
FAS Fas cell surface death receptor -2.89167
TFAP2E transcription factor AP-2 epsilon (activating enhancer binding protein 2 epsilon) -2.89167
ZNF365 zinc finger protein 365 -2.89167
ZNF25 zinc finger protein 25 -2.89167
SS18L2 synovial sarcoma translocation gene on chromosome 18-like 2 -2.89167
SLC26A5 solute carrier family 26 (anion exchanger), member 5 -2.89167
RASGRF2 Ras protein-specific guanine nucleotide-releasing factor 2 -2.89167
A4GALT alpha 1,4-galactosyltransferase -2.89167
CNDP1 carnosine dipeptidase 1 (metallopeptidase M20 family) -2.89167
FXYD2 FXYD domain containing ion transport regulator 2 -2.85947
MSANTD1 Myb/SANT-like DNA-binding domain containing 1 -2.85947
SOWAHB sosondowah ankyrin repeat domain family member B -2.85947
TNS4 tensin 4 -2.85947
ADRA1B adrenoceptor alpha 1B -2.85947
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32) -2.85947
A1CF APOBEC1 complementation factor -2.85947
COL8A2 collagen, type VIII, alpha 2 -2.85947
CCDC68 coiled-coil domain containing 68 -2.85947
SLC46A2 solute carrier family 46, member 2 -2.85947
ALOX15 arachidonate 15-lipoxygenase -2.85947
CES3 carboxylesterase 3 -2.85947
TMPRSS11F transmembrane protease, serine 11F -2.85947
HPCAL4 hippocalcin like 4 -2.85947
RDH16 retinol dehydrogenase 16 (all-trans) -2.85947
NHLRC1 NHL repeat containing E3 ubiquitin protein ligase 1 -2.85947
REEP1 receptor accessory protein 1 -2.85947
STYXL2 serine/threonine/tyrosine interacting like 2 -2.85947
FGF18 fibroblast growth factor 18 -2.85947
CNGB3 cyclic nucleotide gated channel beta 3 -2.85947
LYPD5 LY6/PLAUR domain containing 5 -2.85947
PSKH2 protein serine kinase H2 -2.85947
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled -2.85947
CD226 CD226 molecule -2.85947
SLC52A1 solute carrier family 52 (riboflavin transporter), member 1 -2.85947
GNMT glycine N-methyltransferase -2.85947
TSPAN16 tetraspanin 16 -2.85947
ATMIN ATM interactor -2.83002
N4BP2L1 NEDD4 binding protein 2-like 1 -2.76396
AGAP4 ArfGAP with GTPase domain, ankyrin repeat and PH domain 4 -2.70586
RAMP1 receptor (G protein-coupled) activity modifying protein 1 -2.7039
WBP2NL WBP2 N-terminal like -2.7039
NUTM2E NUT family member 2E -2.69978
SEMA4F sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F -2.69978
COG7 component of oligomeric golgi complex 7 -2.69824
ATOSB atos homolog B -2.69318
LAG3 lymphocyte-activation gene 3 -2.69318
TTYH2 tweety family member 2 -2.69318
OLFM3 olfactomedin 3 -2.68118
CAND1 cullin-associated and neddylation-dissociated 1 -2.68118
OR1F1 olfactory receptor, family 1, subfamily F, member 1 -2.68118
GRAMD1B GRAM domain containing 1B -2.5618
SFXN5 sideroflexin 5 -2.52669
CYGB cytoglobin -2.5185
MCOLN1 mucolipin 1 -2.50565
TRPV1 transient receptor potential cation channel, subfamily V, member 1 -2.47225
CYP11A1 cytochrome P450, family 11, subfamily A, polypeptide 1 -2.45452
PCDH7 protocadherin 7 -2.43738
PCTP phosphatidylcholine transfer protein -2.43278
TEX14 testis expressed 14 -2.4241
SLC44A2 solute carrier family 44 (choline transporter), member 2 -2.42142
IPO9 importin 9 -2.41751
LIN52 lin-52 DREAM MuvB core complex component -2.39689
XAB2 XPA binding protein 2 -2.39349
CACTIN cactin, spliceosome C complex subunit -2.3789
BRI3BP BRI3 binding protein -2.29963
BOLA1 bolA family member 1 -2.29614
GAS2L1 growth arrest-specific 2 like 1 -2.29331
ZNF121 zinc finger protein 121 -2.27665
CDKL4 cyclin-dependent kinase-like 4 -2.27665
TMEM229B transmembrane protein 229B -2.27665
OR56A1 olfactory receptor, family 56, subfamily A, member 1 -2.27665
UBXN2A UBX domain protein 2A -2.27665
TBL1X transducin (beta)-like 1X-linked -2.27665
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1 -2.27665
RNF38 ring finger protein 38 -2.27665
CFAP100 cilia and flagella associated protein 100 -2.27665
RABGAP1 RAB GTPase activating protein 1 -2.26642
SPARCL1 SPARC-like 1 (hevin) -2.24821
ZNF268 zinc finger protein 268 -2.24335
VTA1 vesicle (multivesicular body) trafficking 1 -2.23008
ZNF507 zinc finger protein 507 -2.23008
FAF1 Fas (TNFRSF6) associated factor 1 -2.22929
BCKDHA branched chain keto acid dehydrogenase E1, alpha polypeptide -2.22919
FAM117A family with sequence similarity 117, member A -2.22777
SDC3 syndecan 3 -2.20118
ADAM33 ADAM metallopeptidase domain 33 -2.17801
HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1 -2.17801
SYMPK symplekin -2.17597
GPER1 G protein-coupled estrogen receptor 1 -2.16577
PRDX2 peroxiredoxin 2 -2.144
PKD1L3 polycystic kidney disease 1-like 3 -2.13485
PXMP2 peroxisomal membrane protein 2, 22kDa -2.1306
MRPS12 mitochondrial ribosomal protein S12 -2.11286
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific) -2.11094
ZNF607 zinc finger protein 607 -2.09273
AP5B1 adaptor-related protein complex 5, beta 1 subunit -2.09273
GRWD1 glutamate-rich WD repeat containing 1 -2.07926
IFNAR2 interferon (alpha, beta and omega) receptor 2 -2.07518
SYP synaptophysin -2.0706
EEFSEC eukaryotic elongation factor, selenocysteine-tRNA-specific -2.0706
WSCD1 WSC domain containing 1 -2.06913
RMND5A required for meiotic nuclear division 5 homolog A (S. cerevisiae) -2.06833
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) -2.06799
MIER2 mesoderm induction early response 1, family member 2 -2.05754
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 -2.05419
NEURL1 neuralized E3 ubiquitin protein ligase 1 -2.03992
GLMN glomulin, FKBP associated protein -2.03631
PPP2R3B protein phosphatase 2, regulatory subunit B'', beta -2.03631
ZNF649 zinc finger protein 649 -2.03398
DGKI diacylglycerol kinase, iota -2.01989