| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | caspase recruitment domain family, member 11|The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). This protein has a domain structure similar to that of CARD14 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. When expressed in cells, this protein activated NF-kappaB and induced the phosphorylation of BCL10. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 84433) |
| External Link | https://ncbi.nlm.nih.gov/gene/84433 |
| Similar Terms | |
| Downloads & Tools |
497 genes differentially expressed following the CARD11 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PCNA | proliferating cell nuclear antigen | 0.0185817 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.0143754 |
| LTF | lactotransferrin | 0.0135019 |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 | 0.0120938 |
| CDC20 | cell division cycle 20 | 0.0119067 |
| AMACR | alpha-methylacyl-CoA racemase | 0.0112415 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) | 0.0105377 |
| SCGB2A1 | secretoglobin, family 2A, member 1 | 0.0105254 |
| GALNT6 | polypeptide N-acetylgalactosaminyltransferase 6 | 0.0101421 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.00986332 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | 0.00972073 |
| TUBA1A | tubulin, alpha 1a | 0.00965849 |
| FAM171A1 | family with sequence similarity 171, member A1 | 0.00949967 |
| SLC44A4 | solute carrier family 44, member 4 | 0.00948975 |
| DCXR | dicarbonyl/L-xylulose reductase | 0.00934144 |
| SLC22A4 | solute carrier family 22 (organic cation/zwitterion transporter), member 4 | 0.00924232 |
| HSD11B1 | hydroxysteroid (11-beta) dehydrogenase 1 | 0.00920855 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0091871 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.00911265 |
| ASRGL1 | asparaginase like 1 | 0.00901919 |
| HMGB3 | high mobility group box 3 | 0.00895441 |
| PDZK1 | PDZ domain containing 1 | 0.00877904 |
| PADI2 | peptidyl arginine deiminase, type II | 0.00875737 |
| MYRIP | myosin VIIA and Rab interacting protein | 0.00873605 |
| TPM2 | tropomyosin 2 (beta) | 0.00871352 |
| PBLD | phenazine biosynthesis-like protein domain containing | 0.00868167 |
| MCAM | melanoma cell adhesion molecule | 0.00856931 |
| RASSF2 | Ras association (RalGDS/AF-6) domain family member 2 | 0.00854243 |
| CCN2 | cellular communication network factor 2 | 0.00829706 |
| PCLAF | PCNA clamp associated factor | 0.00829691 |
| HS3ST1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 1 | 0.00828397 |
| NFIB | nuclear factor I/B | 0.0082755 |
| PUF60 | poly-U binding splicing factor 60KDa | 0.00825293 |
| GINS2 | GINS complex subunit 2 (Psf2 homolog) | 0.00823137 |
| ARL3 | ADP-ribosylation factor-like 3 | 0.00815735 |
| PER2 | period circadian clock 2 | 0.00812544 |
| DMD | dystrophin | 0.00804817 |
| PCYOX1 | prenylcysteine oxidase 1 | 0.0080399 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.00802938 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 0.00796623 |
| IMPDH2 | IMP (inosine 5'-monophosphate) dehydrogenase 2 | 0.00788363 |
| MSLN | mesothelin | 0.00784774 |
| TOX3 | TOX high mobility group box family member 3 | 0.00782234 |
| LEFTY1 | left-right determination factor 1 | 0.00776665 |
| RAB40B | RAB40B, member RAS oncogene family | 0.00772803 |
| DRAM1 | DNA-damage regulated autophagy modulator 1 | 0.00768763 |
| ODAM | odontogenic, ameloblast asssociated | 0.00764579 |
| SNRPB | small nuclear ribonucleoprotein polypeptides B and B1 | 0.00760862 |
| EFEMP1 | EGF containing fibulin-like extracellular matrix protein 1 | 0.00760017 |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit | 0.00757386 |
| DHTKD1 | dehydrogenase E1 and transketolase domain containing 1 | 0.00754429 |
| DIXDC1 | DIX domain containing 1 | 0.00749725 |
| SEC14L2 | SEC14-like 2 (S. cerevisiae) | 0.0074835 |
| TMEM47 | transmembrane protein 47 | 0.00747211 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | 0.00746325 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.00745988 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 | 0.00745769 |
| ADH1C | alcohol dehydrogenase 1C (class I), gamma polypeptide | 0.00744853 |
| ESR1 | estrogen receptor 1 | 0.00744664 |
| CCNA2 | cyclin A2 | 0.00736093 |
| GINS1 | GINS complex subunit 1 (Psf1 homolog) | 0.00731488 |
| LIG1 | ligase I, DNA, ATP-dependent | 0.00730275 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | 0.00726171 |
| CRYBG1 | crystallin beta-gamma domain containing 1 | 0.00725492 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | 0.00723066 |
| SEPHS1 | selenophosphate synthetase 1 | 0.00722685 |
| QDPR | quinoid dihydropteridine reductase | 0.00721961 |
| RFNG | RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase | 0.00718942 |
| NUDT21 | nudix (nucleoside diphosphate linked moiety X)-type motif 21 | 0.00718616 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | 0.00717264 |
| ZBED1 | zinc finger, BED-type containing 1 | 0.00716576 |
| TYMS | thymidylate synthetase | 0.0071642 |
| YTHDF1 | YTH N(6)-methyladenosine RNA binding protein 1 | 0.00713307 |
| HMGB2 | high mobility group box 2 | 0.0071163 |
| MT1F | metallothionein 1F | 0.00710744 |
| SERPINB6 | serpin peptidase inhibitor, clade B (ovalbumin), member 6 | 0.00709953 |
| ANOS1 | anosmin 1 | 0.00708902 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.00708394 |
| ADAMDEC1 | ADAM-like, decysin 1 | 0.00707441 |
| TFDP1 | transcription factor Dp-1 | 0.00705897 |
| MT1H | metallothionein 1H | 0.00702669 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.00702021 |
| PLCB4 | phospholipase C, beta 4 | 0.00700187 |
| GCAT | glycine C-acetyltransferase | 0.00697413 |
| NME4 | NME/NM23 nucleoside diphosphate kinase 4 | 0.00696601 |
| SMAD6 | SMAD family member 6 | 0.00695932 |
| ANPEP | alanyl (membrane) aminopeptidase | 0.00695903 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 | 0.00693858 |
| PBX1 | pre-B-cell leukemia homeobox 1 | 0.00691511 |
| GRB14 | growth factor receptor-bound protein 14 | 0.00691465 |
| CRISP3 | cysteine-rich secretory protein 3 | 0.00690523 |
| MSMB | microseminoprotein, beta- | 0.00690225 |
| TSPAN1 | tetraspanin 1 | 0.00689286 |
| MLF1 | myeloid leukemia factor 1 | 0.00689234 |
| RHOBTB1 | Rho-related BTB domain containing 1 | 0.00687948 |
| ADRA2A | adrenoceptor alpha 2A | 0.00684134 |
| S100P | S100 calcium binding protein P | 0.00683363 |
| BIRC5 | baculoviral IAP repeat containing 5 | 0.00683215 |
| FOXM1 | forkhead box M1 | 0.00680863 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.00679827 |
| ASF1B | anti-silencing function 1B histone chaperone | 0.00678109 |
| BAMBI | BMP and activin membrane-bound inhibitor | 0.00677981 |
| TRIP13 | thyroid hormone receptor interactor 13 | 0.00677923 |
| THBS1 | thrombospondin 1 | 0.00675079 |
| MMRN1 | multimerin 1 | 0.00674416 |
| HELLS | helicase, lymphoid-specific | 0.00672824 |
| SULT1E1 | sulfotransferase family 1E, estrogen-preferring, member 1 | 0.0067253 |
| LDLRAD4 | low density lipoprotein receptor class A domain containing 4 | 0.00670472 |
| CHKB | choline kinase beta | 0.00668595 |
| MCM6 | minichromosome maintenance complex component 6 | 0.00661539 |
| TM7SF3 | transmembrane 7 superfamily member 3 | 0.00660469 |
| MT1HL1 | metallothionein 1H-like 1 | 0.00660445 |
| SUMO3 | small ubiquitin-like modifier 3 | 0.00656369 |
| TADA2A | transcriptional adaptor 2A | 0.00656247 |
| LTA4H | leukotriene A4 hydrolase | 0.00655671 |
| AHI1 | Abelson helper integration site 1 | 0.00655649 |
| TUBB4B | tubulin, beta 4B class IVb | 0.00653246 |
| MGP | matrix Gla protein | 0.00652943 |
| PXMP2 | peroxisomal membrane protein 2, 22kDa | 0.00650117 |
| MYO5C | myosin VC | 0.00649458 |
| EHHADH | enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase | 0.00649454 |
| SIVA1 | SIVA1, apoptosis-inducing factor | 0.00647557 |
| NMT2 | N-myristoyltransferase 2 | 0.00646787 |
| KDM5D | lysine (K)-specific demethylase 5D | 0.006426 |
| LY75 | lymphocyte antigen 75 | 0.00642197 |
| STK38L | serine/threonine kinase 38 like | 0.00641767 |
| CLEC11A | C-type lectin domain family 11, member A | 0.00640041 |
| STOM | stomatin | 0.00635808 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | 0.00634288 |
| PCGF2 | polycomb group ring finger 2 | 0.00632023 |
| VOPP1 | vesicular, overexpressed in cancer, prosurvival protein 1 | 0.00631768 |
| PRPF4 | pre-mRNA processing factor 4 | 0.00630113 |
| SALL1 | spalt-like transcription factor 1 | 0.00627538 |
| CDCA4 | cell division cycle associated 4 | 0.00626928 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | 0.00625237 |
| SUCLG2 | succinate-CoA ligase, GDP-forming, beta subunit | 0.00623516 |
| AQP9 | aquaporin 9 | 0.00621731 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | 0.00619838 |
| C8ORF4 | chromosome 8 open reading frame 4 | 0.00618557 |
| BMP6 | bone morphogenetic protein 6 | 0.00617184 |
| DCUN1D4 | DCN1, defective in cullin neddylation 1, domain containing 4 | 0.00616411 |
| CRYL1 | crystallin, lambda 1 | 0.00615651 |
| DHFR | dihydrofolate reductase | 0.00613979 |
| MTHFD1 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase | 0.00613716 |
| MT1E | metallothionein 1E | 0.00613187 |
| NEBL | nebulette | 0.00611803 |
| WWOX | WW domain containing oxidoreductase | 0.0061089 |
| ELAPOR1 | endosome-lysosome associated apoptosis and autophagy regulator 1 | 0.00610153 |
| SLC5A6 | solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 | 0.00607686 |
| MCM2 | minichromosome maintenance complex component 2 | 0.00607646 |
| LRIG1 | leucine-rich repeats and immunoglobulin-like domains 1 | 0.00606213 |
| CPS1 | carbamoyl-phosphate synthase 1, mitochondrial | 0.00605545 |
| IMPA2 | inositol(myo)-1(or 4)-monophosphatase 2 | 0.00605512 |
| ALDH2 | aldehyde dehydrogenase 2 family (mitochondrial) | 0.0060518 |
| ADI1 | acireductone dioxygenase 1 | 0.00604226 |
| NUDT6 | nudix (nucleoside diphosphate linked moiety X)-type motif 6 | 0.00603761 |
| PER3 | period circadian clock 3 | 0.00602204 |
| CALML4 | calmodulin-like 4 | 0.00602071 |
| UGT2A3 | UDP glucuronosyltransferase 2 family, polypeptide A3 | 0.00602042 |
| PIP5K1B | phosphatidylinositol-4-phosphate 5-kinase, type I, beta | 0.00599443 |
| NPY | neuropeptide Y | 0.00599177 |
| ZNF204P | zinc finger protein 204, pseudogene | 0.00599052 |
| GLYAT | glycine-N-acyltransferase | 0.00598482 |
| OLFM4 | olfactomedin 4 | 0.00598467 |
| TSPYL4 | TSPY-like 4 | 0.0059772 |
| ALDH18A1 | aldehyde dehydrogenase 18 family, member A1 | 0.00595861 |
| GPD1L | glycerol-3-phosphate dehydrogenase 1-like | 0.00595709 |
| SH3BP4 | SH3-domain binding protein 4 | 0.005956 |
| IL17RB | interleukin 17 receptor B | 0.00594642 |
| MEF2C | myocyte enhancer factor 2C | 0.005941 |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 | 0.00591952 |
| SHCBP1 | SHC SH2-domain binding protein 1 | 0.00591245 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.00589886 |
| TOR1A | torsin family 1, member A (torsin A) | 0.00589661 |
| CRIP1 | cysteine-rich protein 1 (intestinal) | 0.00589607 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | 0.00588862 |
| COX15 | cytochrome c oxidase assembly homolog 15 (yeast) | 0.00587481 |
| GBA3 | glucosidase, beta, acid 3 (gene/pseudogene) | 0.00586643 |
| EPAS1 | endothelial PAS domain protein 1 | 0.00586633 |
| CDK2AP1 | cyclin-dependent kinase 2 associated protein 1 | 0.00584338 |
| DNAJC9 | DnaJ (Hsp40) homolog, subfamily C, member 9 | 0.00583163 |
| ARID4A | AT rich interactive domain 4A (RBP1-like) | 0.00582983 |
| HSDL2 | hydroxysteroid dehydrogenase like 2 | 0.00582651 |
| ADH6 | alcohol dehydrogenase 6 (class V) | 0.00582509 |
| IQCG | IQ motif containing G | 0.00579004 |
| LSM2 | LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae) | 0.00577084 |
| DACH1 | dachshund family transcription factor 1 | 0.0057681 |
| SAP30 | Sin3A-associated protein, 30kDa | 0.00575629 |
| PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 | 0.00574983 |
| PRR5L | proline rich 5 like | 0.00574492 |
| CADPS2 | Ca++-dependent secretion activator 2 | 0.00574003 |
| UNG | uracil-DNA glycosylase | 0.00573947 |
| THYN1 | thymocyte nuclear protein 1 | 0.00573822 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | 0.00572725 |
| UBR7 | ubiquitin protein ligase E3 component n-recognin 7 (putative) | 0.00572205 |
| CUX2 | cut-like homeobox 2 | 0.00571825 |
| FHL1 | four and a half LIM domains 1 | 0.00571476 |
| AKAP7 | A kinase (PRKA) anchor protein 7 | 0.00571347 |
| TSEN2 | TSEN2 tRNA splicing endonuclease subunit | 0.00570986 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | 0.00570243 |
| NOVA1 | neuro-oncological ventral antigen 1 | 0.00569314 |
| NAAA | N-acylethanolamine acid amidase | 0.00568483 |
| VANGL1 | VANGL planar cell polarity protein 1 | 0.00567407 |
| GPSM2 | G-protein signaling modulator 2 | 0.00566819 |
| GCK | glucokinase (hexokinase 4) | 0.00566568 |
| CHEK1 | checkpoint kinase 1 | 0.00565584 |
| ADAM28 | ADAM metallopeptidase domain 28 | 0.00564966 |
| FAM149A | family with sequence similarity 149, member A | 0.00563378 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | 0.0056287 |
| CBR3 | carbonyl reductase 3 | 0.00562481 |
| EMX2 | empty spiracles homeobox 2 | 0.00561967 |
| IL10RB | interleukin 10 receptor, beta | 0.00560405 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | 0.00557876 |
| ANG | angiogenin, ribonuclease, RNase A family, 5 | 0.0055774 |
| ALDH8A1 | aldehyde dehydrogenase 8 family, member A1 | 0.00557699 |
| TTC19 | tetratricopeptide repeat domain 19 | 0.00557258 |
| RPGRIP1L | RPGRIP1-like | 0.00554684 |
| NASP | nuclear autoantigenic sperm protein (histone-binding) | 0.00554424 |
| CSF2RB | colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) | 0.00553836 |
| SLC27A5 | solute carrier family 27 (fatty acid transporter), member 5 | 0.00553593 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.00552406 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | 0.00551876 |
| IVNS1ABP | influenza virus NS1A binding protein | 0.00551568 |
| IRX5 | iroquois homeobox 5 | 0.00551483 |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 | 0.00551206 |
| CRYM | crystallin, mu | 0.00551176 |
| CCDC85B | coiled-coil domain containing 85B | 0.00550974 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | 0.00547711 |
| GALNT11 | polypeptide N-acetylgalactosaminyltransferase 11 | 0.00546998 |
| BBS7 | Bardet-Biedl syndrome 7 | 0.00546655 |
| MCM5 | minichromosome maintenance complex component 5 | 0.0054647 |
| EOGT | EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0054604 |
| ERG | v-ets avian erythroblastosis virus E26 oncogene homolog | 0.00545548 |
| ALDH5A1 | aldehyde dehydrogenase 5 family, member A1 | 0.00545241 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.00544809 |
| JADE2 | jade family PHD finger 2 | 0.00543402 |
| DUSP3 | dual specificity phosphatase 3 | 0.00539768 |
| ERLIN1 | ER lipid raft associated 1 | 0.00538822 |
| RPS6KA1 | ribosomal protein S6 kinase, 90kDa, polypeptide 1 | 0.00537106 |
| CDS2 | CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2 | 0.00536707 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | 0.00536577 |
| PLK1 | polo-like kinase 1 | 0.00536027 |
| ST6GAL1 | ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 | 0.00534529 |
| GK3P | glycerol kinase 3 pseudogene | 0.00533987 |
| UBE2J1 | ubiquitin-conjugating enzyme E2, J1 | 0.0053391 |
| GPX4 | glutathione peroxidase 4 | 0.00533565 |
| COX16 | COX16 cytochrome c oxidase assembly homolog (S. cerevisiae) | 0.00532498 |
| IMPACT | impact RWD domain protein | 0.00531866 |
| SPATA7 | spermatogenesis associated 7 | 0.00531427 |
| NQO2 | NAD(P)H dehydrogenase, quinone 2 | 0.00531176 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.015792 |
| ASS1 | argininosuccinate synthase 1 | -0.0141912 |
| MAGEA3 | melanoma antigen family A3 | -0.0139387 |
| ATF3 | activating transcription factor 3 | -0.0136674 |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 | -0.0131193 |
| PEG10 | paternally expressed 10 | -0.0126795 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.0120718 |
| XIC | X chromosome inactivation center | -0.0120341 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.0119503 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | -0.0118053 |
| SNAI2 | snail family zinc finger 2 | -0.0112109 |
| RGS16 | regulator of G-protein signaling 16 | -0.010892 |
| EGR1 | early growth response 1 | -0.010794 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0105617 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0105409 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0104934 |
| SUPV3L1 | suppressor of var1, 3-like 1 (S. cerevisiae) | -0.0104547 |
| CLEC2B | C-type lectin domain family 2, member B | -0.0102624 |
| DCN | decorin | -0.0102243 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) | -0.0101881 |
| JUNB | jun B proto-oncogene | -0.0100763 |
| SSX1 | synovial sarcoma, X breakpoint 1 | -0.00990466 |
| HSPA1A | heat shock 70kDa protein 1A | -0.00975621 |
| STK10 | serine/threonine kinase 10 | -0.00972921 |
| LEF1 | lymphoid enhancer-binding factor 1 | -0.00967434 |
| HMOX1 | heme oxygenase 1 | -0.00958971 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -0.00945303 |
| MMP2 | matrix metallopeptidase 2 | -0.00937556 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | -0.00929941 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) | -0.00926562 |
| PGGHG | protein-glucosylgalactosylhydroxylysine glucosidase | -0.0092243 |
| AEBP1 | AE binding protein 1 | -0.0091455 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | -0.00898381 |
| ADM | adrenomedullin | -0.00898341 |
| EIF5A | eukaryotic translation initiation factor 5A | -0.00891406 |
| LRRC15 | leucine rich repeat containing 15 | -0.00884674 |
| GPC3 | glypican 3 | -0.00883653 |
| SFRP4 | secreted frizzled-related protein 4 | -0.00880743 |
| COL15A1 | collagen, type XV, alpha 1 | -0.00877629 |
| RTN2 | reticulon 2 | -0.00877611 |
| COL11A1 | collagen, type XI, alpha 1 | -0.00876484 |
| HIST1H2BK | histone cluster 1, H2bk | -0.0086843 |
| PIEZO2 | piezo-type mechanosensitive ion channel component 2 | -0.00862598 |
| THBS2 | thrombospondin 2 | -0.00862167 |
| DDR2 | discoidin domain receptor tyrosine kinase 2 | -0.00859512 |
| HIST1H2AC | histone cluster 1, H2ac | -0.00838399 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | -0.00834393 |
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide | -0.00829198 |
| LPIN1 | lipin 1 | -0.00822779 |
| SPON2 | spondin 2, extracellular matrix protein | -0.00821208 |
| SLC3A2 | solute carrier family 3 (amino acid transporter heavy chain), member 2 | -0.00815283 |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) | -0.00812181 |
| NPTX2 | neuronal pentraxin II | -0.00810413 |
| SC5D | sterol-C5-desaturase | -0.00807999 |
| ABHD3 | abhydrolase domain containing 3 | -0.00807114 |
| DCT | dopachrome tautomerase | -0.00806591 |
| PCOLCE | procollagen C-endopeptidase enhancer | -0.00805851 |
| CCL2 | chemokine (C-C motif) ligand 2 | -0.00794928 |
| GBP2 | guanylate binding protein 2, interferon-inducible | -0.00793227 |
| CTSK | cathepsin K | -0.00789288 |
| FGA | fibrinogen alpha chain | -0.00785738 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | -0.00785281 |
| GPX2 | glutathione peroxidase 2 | -0.00782278 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.00781211 |
| ANKRD10 | ankyrin repeat domain 10 | -0.00774556 |
| HOXC6 | homeobox C6 | -0.00774048 |
| ELN | elastin | -0.00773885 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.00773826 |
| STC2 | stanniocalcin 2 | -0.00771948 |
| FBLN1 | fibulin 1 | -0.0076967 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.00767716 |
| FCMR | Fc fragment of IgM receptor | -0.00766728 |
| TWIST1 | twist family bHLH transcription factor 1 | -0.00766358 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | -0.00765476 |
| MFAP4 | microfibrillar-associated protein 4 | -0.00763908 |
| NAV3 | neuron navigator 3 | -0.00763203 |
| LGALS8 | lectin, galactoside-binding, soluble, 8 | -0.00759981 |
| HIST1H2BD | histone cluster 1, H2bd | -0.00757921 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.00757189 |
| P3H2 | prolyl 3-hydroxylase 2 | -0.0075581 |
| NEFM | neurofilament, medium polypeptide | -0.00751946 |
| MAGEA12 | melanoma antigen family A12 | -0.00741431 |
| KRT14 | keratin 14, type I | -0.00740584 |
| ACKR1 | atypical chemokine receptor 1 (Duffy blood group) | -0.00730982 |
| IRS2 | insulin receptor substrate 2 | -0.00727351 |
| IL32 | interleukin 32 | -0.00724157 |
| RAP1GAP | RAP1 GTPase activating protein | -0.00722674 |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') | -0.0072156 |
| G0S2 | G0/G1 switch 2 | -0.00719628 |
| CHIC2 | cysteine-rich hydrophobic domain 2 | -0.00717471 |
| CTSL | cathepsin L | -0.00716522 |
| COL14A1 | collagen, type XIV, alpha 1 | -0.00715474 |
| SLC7A8 | solute carrier family 7 (amino acid transporter light chain, L system), member 8 | -0.00712097 |
| TPSAB1 | tryptase alpha/beta 1 | -0.00711259 |
| F13A1 | coagulation factor XIII, A1 polypeptide | -0.00708889 |
| GAS7 | growth arrest-specific 7 | -0.00708454 |
| GOLGA8A | golgin A8 family, member A | -0.00706487 |
| CD69 | CD69 molecule | -0.00706356 |
| FADS3 | fatty acid desaturase 3 | -0.00705306 |
| EVI2A | ecotropic viral integration site 2A | -0.00705162 |
| CITED1 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1 | -0.0070494 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.00702892 |
| GJA1 | gap junction protein, alpha 1, 43kDa | -0.00701532 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | -0.00701527 |
| ALB | albumin | -0.00698374 |
| TM4SF4 | transmembrane 4 L six family member 4 | -0.00697662 |
| CX3CR1 | chemokine (C-X3-C motif) receptor 1 | -0.00696291 |
| HSPB8 | heat shock 22kDa protein 8 | -0.00696265 |
| NIT1 | nitrilase 1 | -0.00692629 |
| TPP2 | tripeptidyl peptidase II | -0.00692293 |
| MEST | mesoderm specific transcript | -0.00691964 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.00690805 |
| DUSP5 | dual specificity phosphatase 5 | -0.00689199 |
| TES | testin LIM domain protein | -0.00687576 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | -0.00685952 |
| ATP6V1C1 | ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 | -0.00682348 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | -0.00680966 |
| OPN3 | opsin 3 | -0.00680254 |
| ANK2 | ankyrin 2, neuronal | -0.00680107 |
| IL6 | interleukin 6 | -0.00678309 |
| SLC2A6 | solute carrier family 2 (facilitated glucose transporter), member 6 | -0.00676581 |
| CD36 | CD36 molecule (thrombospondin receptor) | -0.00676216 |
| SEPP1 | selenoprotein P, plasma, 1 | -0.00676 |
| HIST1H2BH | histone cluster 1, H2bh | -0.00675365 |
| C11ORF21 | chromosome 11 open reading frame 21 | -0.00675186 |
| NGFRAP1 | nerve growth factor receptor (TNFRSF16) associated protein 1 | -0.00674621 |
| COL16A1 | collagen, type XVI, alpha 1 | -0.00674238 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | -0.00671317 |
| REXO2 | RNA exonuclease 2 | -0.00671201 |
| LY96 | lymphocyte antigen 96 | -0.00670807 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.00669746 |
| CTSA | cathepsin A | -0.00669114 |
| INHBB | inhibin, beta B | -0.00668287 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.00660342 |
| MAPK8IP3 | mitogen-activated protein kinase 8 interacting protein 3 | -0.00660108 |
| MAGEA1 | melanoma antigen family A1 | -0.00659701 |
| CEL | carboxyl ester lipase | -0.00658865 |
| FABP4 | fatty acid binding protein 4, adipocyte | -0.00655 |
| WDR45 | WD repeat domain 45 | -0.00654883 |
| KDM6A | lysine (K)-specific demethylase 6A | -0.0065482 |
| SPRY2 | sprouty homolog 2 (Drosophila) | -0.0065441 |
| CREG1 | cellular repressor of E1A-stimulated genes 1 | -0.00650962 |
| MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B | -0.0064848 |
| HIRA | histone cell cycle regulator | -0.00647181 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -0.00641888 |
| BEX1 | brain expressed, X-linked 1 | -0.00636255 |
| FMOD | fibromodulin | -0.00636197 |
| TRIB3 | tribbles pseudokinase 3 | -0.00635599 |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) | -0.00634093 |
| DLK1 | delta-like 1 homolog (Drosophila) | -0.00633794 |
| CLTB | clathrin, light chain B | -0.00633537 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.00632446 |
| BLVRB | biliverdin reductase B | -0.00632301 |
| S100A9 | S100 calcium binding protein A9 | -0.00631338 |
| CALML3 | calmodulin-like 3 | -0.00631151 |
| GLA | galactosidase, alpha | -0.00630472 |
| TBL2 | transducin (beta)-like 2 | -0.00630382 |
| EGFL6 | EGF-like-domain, multiple 6 | -0.00626785 |
| CCN3 | cellular communication network factor 3 | -0.00626083 |
| GAL | galanin/GMAP prepropeptide | -0.00623684 |
| SCD5 | stearoyl-CoA desaturase 5 | -0.00623339 |
| TFRC | transferrin receptor | -0.00622857 |
| CDC42 | cell division cycle 42 | -0.00622514 |
| HK2 | hexokinase 2 | -0.0062137 |
| DRAP1 | DR1-associated protein 1 (negative cofactor 2 alpha) | -0.00617796 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.00615788 |
| SARS1 | seryl-tRNA synthetase 1 | -0.00613196 |
| KRT17 | keratin 17, type I | -0.00612277 |
| IL24 | interleukin 24 | -0.00612242 |
| ADAM12 | ADAM metallopeptidase domain 12 | -0.00612173 |
| PERP | PERP, TP53 apoptosis effector | -0.00611378 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.00610069 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | -0.00608409 |
| L1CAM | L1 cell adhesion molecule | -0.00606614 |
| COL9A3 | collagen, type IX, alpha 3 | -0.00605448 |
| CLDN1 | claudin 1 | -0.00605396 |
| ABCC10 | ATP-binding cassette, sub-family C (CFTR/MRP), member 10 | -0.00604389 |
| TARS1 | threonyl-tRNA synthetase 1 | -0.00604236 |
| EPHB6 | EPH receptor B6 | -0.00599451 |
| MRPS30 | mitochondrial ribosomal protein S30 | -0.00599214 |
| STX4 | syntaxin 4 | -0.00598888 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.00594726 |
| GABRE | gamma-aminobutyric acid (GABA) A receptor, epsilon | -0.00593655 |
| OSER1 | oxidative stress responsive serine-rich 1 | -0.00593334 |
| WDR13 | WD repeat domain 13 | -0.00592956 |
| SDC3 | syndecan 3 | -0.00592388 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | -0.00591664 |
| NPC1 | Niemann-Pick disease, type C1 | -0.005901 |
| PPL | periplakin | -0.0058898 |
| TRIM29 | tripartite motif containing 29 | -0.00587005 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.00585949 |
| CCDC86 | coiled-coil domain containing 86 | -0.00585679 |
| LAMB1 | laminin, beta 1 | -0.00585302 |
| NNAT | neuronatin | -0.00584881 |
| EXT1 | exostosin glycosyltransferase 1 | -0.00584131 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.00583995 |
| RNF128 | ring finger protein 128, E3 ubiquitin protein ligase | -0.00582359 |
| TTN | titin | -0.00582007 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.00580976 |
| GTPBP2 | GTP binding protein 2 | -0.0057904 |
| S100A8 | S100 calcium binding protein A8 | -0.00578961 |
| MMP11 | matrix metallopeptidase 11 | -0.00578624 |
| APOA1 | apolipoprotein A-I | -0.00577136 |
| LGALS4 | lectin, galactoside-binding, soluble, 4 | -0.00575426 |
| H1-2 | H1.2 linker histone, cluster member | -0.0057517 |
| HIST2H2BE | histone cluster 2, H2be | -0.0057416 |
| TIMM17B | translocase of inner mitochondrial membrane 17 homolog B (yeast) | -0.0057314 |
| ATP6V0C | ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c | -0.0057201 |
| TENM3 | teneurin transmembrane protein 3 | -0.00571974 |
| HLA-DRB1 | major histocompatibility complex, class II, DR beta 1 | -0.00571326 |
| MIR22HG | MIR22 host gene | -0.0057029 |
| NIBAN1 | niban apoptosis regulator 1 | -0.00569638 |
| MXI1 | MAX interactor 1, dimerization protein | -0.00569264 |
| PRSS3 | protease, serine, 3 | -0.00569066 |
| PLXNC1 | plexin C1 | -0.00568814 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | -0.00568675 |
| CIDEC | cell death-inducing DFFA-like effector c | -0.00568281 |
| PTN | pleiotrophin | -0.00567483 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | -0.00567421 |
| HADHB | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit | -0.00565676 |
| TFAP2C | transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) | -0.0056353 |
| CLCN7 | chloride channel, voltage-sensitive 7 | -0.00563221 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa | -0.00562893 |
| RTCA | RNA 3'-terminal phosphate cyclase | -0.00561816 |
| ORMDL2 | ORMDL sphingolipid biosynthesis regulator 2 | -0.00557726 |
| SVEP1 | sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 | -0.00556388 |
| HLA-DRA | major histocompatibility complex, class II, DR alpha | -0.00556142 |
| TSPAN32 | tetraspanin 32 | -0.00555844 |
| ITGA6 | integrin, alpha 6 | -0.00555639 |
| PTS | 6-pyruvoyltetrahydropterin synthase | -0.00554448 |
| SPRR2B | small proline-rich protein 2B | -0.00553259 |
| DUSP2 | dual specificity phosphatase 2 | -0.00552758 |
| SIN3B | SIN3 transcription regulator family member B | -0.00552082 |
| C1R | complement component 1, r subcomponent | -0.00551762 |
| ESYT1 | extended synaptotagmin-like protein 1 | -0.00551726 |
| ARMCX3 | armadillo repeat containing, X-linked 3 | -0.00550626 |
| HOXD1 | homeobox D1 | -0.00550162 |
| NELL2 | NEL-like 2 (chicken) | -0.00549803 |
| SPANXD | SPANX family, member D | -0.00549643 |
| ISLR | immunoglobulin superfamily containing leucine-rich repeat | -0.00549392 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 | -0.00548335 |
| PRAME | preferentially expressed antigen in melanoma | -0.00548022 |
| GSTA1 | glutathione S-transferase alpha 1 | -0.00547584 |
| BTG3 | BTG family, member 3 | -0.00547488 |
| C3 | complement component 3 | -0.0054731 |
| TMEM70 | transmembrane protein 70 | -0.00546194 |
| USP15 | ubiquitin specific peptidase 15 | -0.00544287 |
