CARD8 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description caspase recruitment domain family, member 8|The protein encoded by this gene belongs to the caspase recruitment domain (CARD)-containing family of proteins, which are involved in pathways leading to activation of caspases or nuclear factor kappa-B (NFKB). This protein may be a component of the inflammasome, a protein complex that plays a role in the activation of proinflammatory caspases. It is thought that this protein acts as an adaptor molecule that negatively regulates NFKB activation, CASP1-dependent IL1B secretion, and apoptosis. Polymorphisms in this gene may be associated with a susceptibility to rheumatoid arthritis. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, May 2010] (NCBI Entrez Gene Database, 22900)
External Link https://ncbi.nlm.nih.gov/gene/22900
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Genes

498 genes differentially expressed following the CARD8 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
HSPB1 heat shock 27kDa protein 1 0.0245395
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 0.0238665
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 0.0213165
SPARCL1 SPARC-like 1 (hevin) 0.0188525
APOD apolipoprotein D 0.0180387
TNNT1 troponin T type 1 (skeletal, slow) 0.0172442
AKAP8 A kinase (PRKA) anchor protein 8 0.0171426
MAT2A methionine adenosyltransferase II, alpha 0.0160842
TSPAN13 tetraspanin 13 0.0151561
DES desmin 0.015039
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) 0.0146957
ADIRF adipogenesis regulatory factor 0.0143781
GPNMB glycoprotein (transmembrane) nmb 0.0143444
HSPB8 heat shock 22kDa protein 8 0.014256
ACTA1 actin, alpha 1, skeletal muscle 0.0142384
COL6A2 collagen, type VI, alpha 2 0.0136743
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 0.0134662
CADM1 cell adhesion molecule 1 0.0134415
EEF1A2 eukaryotic translation elongation factor 1 alpha 2 0.0133243
RTN2 reticulon 2 0.0132062
THY1 Thy-1 cell surface antigen 0.0130641
SPRED2 sprouty-related, EVH1 domain containing 2 0.0128855
MSMB microseminoprotein, beta- 0.0124857
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 0.0124475
VEGFA vascular endothelial growth factor A 0.012447
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D 0.0123883
THBS4 thrombospondin 4 0.0122996
COL15A1 collagen, type XV, alpha 1 0.0122257
MMP1 matrix metallopeptidase 1 0.0122204
MYBPC1 myosin binding protein C, slow type 0.0121959
MT1M metallothionein 1M 0.0121713
METRN meteorin, glial cell differentiation regulator 0.012021
CHN1 chimerin 1 0.011974
EZR ezrin 0.0118479
FGFR3 fibroblast growth factor receptor 3 0.0116241
SCUBE2 signal peptide, CUB domain, EGF-like 2 0.0115806
TNNI2 troponin I type 2 (skeletal, fast) 0.0115494
ISG15 ISG15 ubiquitin-like modifier 0.0113547
CRIP2 cysteine-rich protein 2 0.0113516
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8 0.0112957
MT1E metallothionein 1E 0.0112936
MT1X metallothionein 1X 0.0112251
LYZ lysozyme 0.0110476
CAV1 caveolin 1, caveolae protein, 22kDa 0.0109767
ASPN asporin 0.0107735
TPSAB1 tryptase alpha/beta 1 0.0106881
MIR22HG MIR22 host gene 0.0106542
RABEP2 rabaptin, RAB GTPase binding effector protein 2 0.0106472
MB myoglobin 0.0105635
HSPH1 heat shock 105kDa/110kDa protein 1 0.0105415
KLHL41 kelch-like family member 41 0.0104557
MT1F metallothionein 1F 0.0104055
UCP2 uncoupling protein 2 (mitochondrial, proton carrier) 0.0103968
LGALS1 lectin, galactoside-binding, soluble, 1 0.0103614
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1) 0.0103121
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2 0.0103073
DMBT1 deleted in malignant brain tumors 1 0.0102327
CD40 CD40 molecule, TNF receptor superfamily member 5 0.0102252
OFD1 oral-facial-digital syndrome 1 0.0101947
MFAP2 microfibrillar-associated protein 2 0.0101916
AQP3 aquaporin 3 (Gill blood group) 0.010181
NDRG1 N-myc downstream regulated 1 0.0101625
BANK1 B-cell scaffold protein with ankyrin repeats 1 0.0101247
SGK1 serum/glucocorticoid regulated kinase 1 0.010088
BGN biglycan 0.0100304
CTBP2 C-terminal binding protein 2 0.00996598
COMP cartilage oligomeric matrix protein 0.00993825
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1 0.00989715
ISYNA1 inositol-3-phosphate synthase 1 0.00989392
TNNC2 troponin C type 2 (fast) 0.00987435
FZD5 frizzled class receptor 5 0.00984575
TMSB15A thymosin beta 15a 0.00984504
CCN2 cellular communication network factor 2 0.00978208
ORC1 origin recognition complex, subunit 1 0.00976776
MYL2 myosin, light chain 2, regulatory, cardiac, slow 0.0097438
TFF3 trefoil factor 3 (intestinal) 0.00970182
ALOX15B arachidonate 15-lipoxygenase, type B 0.00964475
TTN titin 0.00962253
SCAF4 SR-related CTD-associated factor 4 0.00961805
FBXO11 F-box protein 11 0.00954763
RRM2 ribonucleotide reductase M2 0.0094749
MT1G metallothionein 1G 0.00946297
MLPH melanophilin 0.00945373
SNX13 sorting nexin 13 0.00944277
ACSL1 acyl-CoA synthetase long-chain family member 1 0.00943752
MS4A1 membrane-spanning 4-domains, subfamily A, member 1 0.00939915
RUFY2 RUN and FYVE domain containing 2 0.00938496
GNMT glycine N-methyltransferase 0.00933167
RAD51AP1 RAD51 associated protein 1 0.00929186
RAP1GAP2 RAP1 GTPase activating protein 2 0.00925743
ESR1 estrogen receptor 1 0.00923967
MKNK2 MAP kinase interacting serine/threonine kinase 2 0.00922905
PLTP phospholipid transfer protein 0.00916073
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 0.0091597
PDLIM5 PDZ and LIM domain 5 0.00911671
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1 0.00911421
MMP2 matrix metallopeptidase 2 0.00908277
VWF von Willebrand factor 0.00907014
GSTA1 glutathione S-transferase alpha 1 0.00904903
GUSB glucuronidase, beta 0.00903957
FGFR2 fibroblast growth factor receptor 2 0.00902842
RGS13 regulator of G-protein signaling 13 0.00900635
PDGFRL platelet-derived growth factor receptor-like 0.00897488
RAMP1 receptor (G protein-coupled) activity modifying protein 1 0.00896988
STC1 stanniocalcin 1 0.00886317
CCL19 chemokine (C-C motif) ligand 19 0.00884193
DPT dermatopontin 0.00881774
SASH1 SAM and SH3 domain containing 1 0.00881687
NOTCH2NL notch 2 N-terminal like 0.00880246
SIK1 salt-inducible kinase 1 0.008793
LPCAT1 lysophosphatidylcholine acyltransferase 1 0.00879029
NDUFA4L2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2 0.00876726
PLXNB2 plexin B2 0.00873086
POU5F1P3 POU class 5 homeobox 1 pseudogene 3 0.00871704
ARHGEF10 Rho guanine nucleotide exchange factor (GEF) 10 0.00870538
TAGLN transgelin 0.00864286
ZNF589 zinc finger protein 589 0.00862281
ADGRG2 adhesion G protein-coupled receptor G2 0.00860615
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin) 0.00853787
ALPL alkaline phosphatase, liver/bone/kidney 0.00851096
PPP1R7 protein phosphatase 1, regulatory subunit 7 0.00845401
ZNF532 zinc finger protein 532 0.00843556
PAX5 paired box 5 0.00843435
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 0.00843058
AZGP1 alpha-2-glycoprotein 1, zinc-binding 0.00842379
CTSA cathepsin A 0.00841784
PYCARD PYD and CARD domain containing 0.00839021
PPP1R3C protein phosphatase 1, regulatory subunit 3C 0.00838065
IL1R1 interleukin 1 receptor, type I 0.0083551
PCSK5 proprotein convertase subtilisin/kexin type 5 0.00831314
REX1BD required for excision 1-B domain containing 0.00825249
SDC4 syndecan 4 0.00820748
RGCC regulator of cell cycle 0.00815486
MXRA7 matrix-remodelling associated 7 0.00814517
PLA1A phospholipase A1 member A 0.00813804
MX1 MX dynamin-like GTPase 1 0.00812858
ANGPTL4 angiopoietin-like 4 0.00812558
NIT1 nitrilase 1 0.00811086
FKBP4 FK506 binding protein 4, 59kDa 0.0080918
PTK2 protein tyrosine kinase 2 0.0080868
ATP2A3 ATPase, Ca++ transporting, ubiquitous 0.00805743
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 0.00803983
YBX3 Y box binding protein 3 0.00802421
QPRT quinolinate phosphoribosyltransferase 0.0080166
TNNC1 troponin C type 1 (slow) 0.00800696
NOTCH3 notch 3 0.00800428
SPON2 spondin 2, extracellular matrix protein 0.00799905
ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3 0.00798906
METTL7A methyltransferase like 7A 0.00795519
ENAH enabled homolog (Drosophila) 0.00792107
MYL1 myosin, light chain 1, alkali; skeletal, fast 0.00790225
FTH1 ferritin, heavy polypeptide 1 0.00787042
BAD BCL2-associated agonist of cell death 0.0078695
MGLL monoglyceride lipase 0.00784391
CCL21 chemokine (C-C motif) ligand 21 0.00783553
ECM1 extracellular matrix protein 1 0.00782891
COL4A2 collagen, type IV, alpha 2 0.00782426
BLNK B-cell linker 0.00781932
TSPO translocator protein (18kDa) 0.00779034
SEC62 SEC62 homolog (S. cerevisiae) 0.00778014
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase 0.00777841
MYH2 myosin, heavy chain 2, skeletal muscle, adult 0.00777752
DSG1 desmoglein 1 0.00774665
ARG2 arginase 2 0.00772727
FILIP1L filamin A interacting protein 1-like 0.00772395
XIC X chromosome inactivation center 0.00772353
HYOU1 hypoxia up-regulated 1 0.00771846
DMTF1 cyclin D binding myb-like transcription factor 1 0.00768133
SNAP23 synaptosomal-associated protein, 23kDa 0.00766721
SKAP2 src kinase associated phosphoprotein 2 0.0076606
HELLS helicase, lymphoid-specific 0.00764198
CDK5RAP3 CDK5 regulatory subunit associated protein 3 0.00763918
FGFR1 fibroblast growth factor receptor 1 0.0076251
KMO kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) 0.00761971
UGT2B4 UDP glucuronosyltransferase 2 family, polypeptide B4 0.00761051
LUC7L3 LUC7-like 3 (S. cerevisiae) 0.00754898
HAUS3 HAUS augmin-like complex, subunit 3 0.00754427
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.0075414
CRIP1 cysteine-rich protein 1 (intestinal) 0.00750961
FGG fibrinogen gamma chain 0.00750704
GRB14 growth factor receptor-bound protein 14 0.00750679
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 0.00750584
RGS5 regulator of G-protein signaling 5 0.00749279
EIF4E2 eukaryotic translation initiation factor 4E family member 2 0.00748331
EFR3A EFR3 homolog A (S. cerevisiae) 0.00748319
CHST1 carbohydrate (keratan sulfate Gal-6) sulfotransferase 1 0.0074823
UPK1B uroplakin 1B 0.00746725
TRIM8 tripartite motif containing 8 0.0074665
PNN pinin, desmosome associated protein 0.00742704
MMP13 matrix metallopeptidase 13 0.00741952
FHL1 four and a half LIM domains 1 0.00741213
DLX5 distal-less homeobox 5 0.00740513
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase 0.00740502
ARGLU1 arginine and glutamate rich 1 0.00740439
PRPF4B pre-mRNA processing factor 4B 0.00739056
SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A 0.00738833
PPAP2A phosphatidic acid phosphatase type 2A 0.00738408
FUBP1 far upstream element (FUSE) binding protein 1 0.00737327
ENO3 enolase 3 (beta, muscle) 0.0073728
PDE10A phosphodiesterase 10A 0.00737246
FXYD2 FXYD domain containing ion transport regulator 2 0.00735865
PELI1 pellino E3 ubiquitin protein ligase 1 0.00735858
PCGF3 polycomb group ring finger 3 0.00734178
SH3BGRL SH3 domain binding glutamate-rich protein like 0.00733285
GPR87 G protein-coupled receptor 87 0.00733271
PNISR PNN-interacting serine/arginine-rich protein 0.00732317
CAMSAP2 calmodulin regulated spectrin-associated protein family, member 2 0.00731546
TPM3 tropomyosin 3 0.00726431
NTAN1 N-terminal asparagine amidase 0.00723732
MAOA monoamine oxidase A 0.00722709
HSPA6 heat shock 70kDa protein 6 (HSP70B') 0.00722092
DGCR8 DGCR8 microprocessor complex subunit 0.00720802
CCNA2 cyclin A2 0.00719629
TM7SF2 transmembrane 7 superfamily member 2 0.00719421
HGD homogentisate 1,2-dioxygenase 0.00717774
CHRDL1 chordin-like 1 0.00717641
PIP prolactin-induced protein 0.00716057
DLX2 distal-less homeobox 2 0.00715499
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.00715329
TCAP titin-cap 0.0071374
ABHD3 abhydrolase domain containing 3 0.00711552
HCRT hypocretin (orexin) neuropeptide precursor 0.00710975
GOLGA8A golgin A8 family, member A 0.00710319
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme 0.00709756
KLC2 kinesin light chain 2 0.0070925
USP13 ubiquitin specific peptidase 13 (isopeptidase T-3) 0.00707609
IRF7 interferon regulatory factor 7 0.00706635
ELN elastin 0.00704752
POU5F1B POU class 5 homeobox 1B 0.00699167
PKP1 plakophilin 1 0.00698642
SCNM1 sodium channel modifier 1 0.00698205
TGFBI transforming growth factor, beta-induced, 68kDa 0.00697472
CASP2 caspase 2, apoptosis-related cysteine peptidase 0.00696974
CD9 CD9 molecule 0.00695707
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 0.0069561
MGP matrix Gla protein 0.00694803
REV1 REV1, polymerase (DNA directed) 0.00693857
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 0.00692568
EFHC1 EF-hand domain (C-terminal) containing 1 0.00690666
NANOG Nanog homeobox 0.00689553
HSPA4 heat shock 70kDa protein 4 0.00687325
ZHX2 zinc fingers and homeoboxes 2 0.00686807
FASN fatty acid synthase 0.00684671
H1-2 H1.2 linker histone, cluster member 0.0068369
HIC2 hypermethylated in cancer 2 0.00683085
MYOT myotilin 0.00681514
FXR1 fragile X mental retardation, autosomal homolog 1 0.00681331
CGA glycoprotein hormones, alpha polypeptide 0.00680526
GBAP1 glucosidase, beta, acid pseudogene 1 0.00678187

decreased expression

Symbol Name Standardized Value
SSBP2 single-stranded DNA binding protein 2 -0.0219923
GNAS GNAS complex locus -0.0210171
TLR4 toll-like receptor 4 -0.0188288
LGALS13 lectin, galactoside-binding, soluble, 13 -0.0180982
ADO 2-aminoethanethiol (cysteamine) dioxygenase -0.0180939
BMP4 bone morphogenetic protein 4 -0.0178303
EGR2 early growth response 2 -0.017669
RAD23B RAD23 homolog B (S. cerevisiae) -0.0164838
PITX3 paired-like homeodomain 3 -0.0162527
MNDA myeloid cell nuclear differentiation antigen -0.0155517
TXLNA taxilin alpha -0.0154269
TM4SF1 transmembrane 4 L six family member 1 -0.0152791
LAPTM4B lysosomal protein transmembrane 4 beta -0.0152541
SOX9 SRY (sex determining region Y)-box 9 -0.0152069
SELL selectin L -0.0144577
BHLHE41 basic helix-loop-helix family, member e41 -0.0142958
TSPAN8 tetraspanin 8 -0.0139519
SOX11 SRY (sex determining region Y)-box 11 -0.013934
CLC Charcot-Leyden crystal galectin -0.0138402
RRAGA Ras-related GTP binding A -0.0138374
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D -0.0138296
KLK6 kallikrein-related peptidase 6 -0.0138105
DIPK1A divergent protein kinase domain 1A -0.013785
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 -0.0134501
AUTS2 autism susceptibility candidate 2 -0.0134161
NID2 nidogen 2 (osteonidogen) -0.0133113
GIMAP4 GTPase, IMAP family member 4 -0.0127728
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein -0.0126096
OXTR oxytocin receptor -0.0125391
RCAN1 regulator of calcineurin 1 -0.0125376
KRT19 keratin 19, type I -0.0123304
PLBD1 phospholipase B domain containing 1 -0.0122017
SORT1 sortilin 1 -0.0121636
PELI2 pellino E3 ubiquitin protein ligase family member 2 -0.0121615
DEFB1 defensin, beta 1 -0.0120081
HACD1 3-hydroxyacyl-CoA dehydratase 1 -0.0116662
HNMT histamine N-methyltransferase -0.0115857
GABRP gamma-aminobutyric acid (GABA) A receptor, pi -0.0115573
BEX4 brain expressed, X-linked 4 -0.0114695
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 -0.0114636
CEMIP cell migration inducing protein, hyaluronan binding -0.0113915
BEX1 brain expressed, X-linked 1 -0.0113291
BAMBI BMP and activin membrane-bound inhibitor -0.0112563
DPYD dihydropyrimidine dehydrogenase -0.0111192
PADI2 peptidyl arginine deiminase, type II -0.0110265
MS4A3 membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) -0.0109935
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 -0.0109795
FCGBP Fc fragment of IgG binding protein -0.0109184
CD53 CD53 molecule -0.0108923
GIMAP6 GTPase, IMAP family member 6 -0.010865
FAM171A1 family with sequence similarity 171, member A1 -0.0108237
CHPT1 choline phosphotransferase 1 -0.0107897
PDGFRA platelet-derived growth factor receptor, alpha polypeptide -0.0105757
GBP1 guanylate binding protein 1, interferon-inducible -0.0105729
NRN1 neuritin 1 -0.010567
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4 -0.0105251
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) -0.0104671
PITX1 paired-like homeodomain 1 -0.0104547
LAPTM5 lysosomal protein transmembrane 5 -0.0104237
HBD hemoglobin, delta -0.0104228
CX3CR1 chemokine (C-X3-C motif) receptor 1 -0.0103944
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) -0.0103894
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1 -0.0103779
KLK10 kallikrein-related peptidase 10 -0.0101599
BPI bactericidal/permeability-increasing protein -0.0100955
ASNS asparagine synthetase (glutamine-hydrolyzing) -0.010087
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 -0.0100091
NAV3 neuron navigator 3 -0.00999977
ARL6IP5 ADP-ribosylation factor-like 6 interacting protein 5 -0.0099743
C5ORF30 chromosome 5 open reading frame 30 -0.00997176
ZNF189 zinc finger protein 189 -0.0099511
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) -0.00994232
TADA2A transcriptional adaptor 2A -0.00991025
PRKCA protein kinase C, alpha -0.00987742
TMOD1 tropomodulin 1 -0.00984094
S100A8 S100 calcium binding protein A8 -0.00980371
LTA4H leukotriene A4 hydrolase -0.00979956
PIP5K1B phosphatidylinositol-4-phosphate 5-kinase, type I, beta -0.00979421
MAGEA3 melanoma antigen family A3 -0.0097518
SLPI secretory leukocyte peptidase inhibitor -0.00971928
LTF lactotransferrin -0.0097125
NDN necdin, melanoma antigen (MAGE) family member -0.00970999
TCTA T-cell leukemia translocation altered -0.00969914
CD69 CD69 molecule -0.00967457
IRF4 interferon regulatory factor 4 -0.00963686
EHF ets homologous factor -0.00960199
KANK1 KN motif and ankyrin repeat domains 1 -0.00952674
TARBP1 TAR (HIV-1) RNA binding protein 1 -0.00948671
HGF hepatocyte growth factor (hepapoietin A; scatter factor) -0.00947903
NR2F1 nuclear receptor subfamily 2, group F, member 1 -0.00946772
RHOBTB3 Rho-related BTB domain containing 3 -0.00938368
ANXA3 annexin A3 -0.00937705
FAM198B family with sequence similarity 198, member B -0.00925995
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase) -0.00923755
PDIA3 protein disulfide isomerase family A, member 3 -0.00922898
ZEB2 zinc finger E-box binding homeobox 2 -0.0091911
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) -0.00915264
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1 -0.00913851
P2RY13 purinergic receptor P2Y, G-protein coupled, 13 -0.00913046
CAPRIN1 cell cycle associated protein 1 -0.00910958
GATA6 GATA binding protein 6 -0.00910313
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1 -0.0090874
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) -0.00904998
S100A9 S100 calcium binding protein A9 -0.00904831
AK2 adenylate kinase 2 -0.00904474
CTSG cathepsin G -0.00904325
ITM2A integral membrane protein 2A -0.00903492
IL6ST interleukin 6 signal transducer -0.00900739
ATP10B ATPase, class V, type 10B -0.00897176
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) -0.00896091
RNASE3 ribonuclease, RNase A family, 3 -0.0089572
TLE4 transducin-like enhancer of split 4 -0.00895385
EGR1 early growth response 1 -0.00892258
CD200 CD200 molecule -0.00891262
ADORA2B adenosine A2b receptor -0.00890771
LRRN3 leucine rich repeat neuronal 3 -0.0088637
ARPC5 actin related protein 2/3 complex, subunit 5, 16kDa -0.00886083
AP2B1 adaptor-related protein complex 2, beta 1 subunit -0.00884041
OLFM4 olfactomedin 4 -0.00883316
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 -0.00882386
VLDLR very low density lipoprotein receptor -0.00881481
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) -0.00876963
RBBP4 retinoblastoma binding protein 4 -0.00876302
DDX11 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 -0.00876154
ALOX5AP arachidonate 5-lipoxygenase-activating protein -0.00875549
EHBP1 EH domain binding protein 1 -0.00865184
LRRC8D leucine rich repeat containing 8 family, member D -0.00864721
PNMA8A PNMA family member 8A -0.00862959
PJA2 praja ring finger 2, E3 ubiquitin protein ligase -0.00861034
CPVL carboxypeptidase, vitellogenic-like -0.00857352
BTBD3 BTB (POZ) domain containing 3 -0.00854507
NCKAP1L NCK-associated protein 1-like -0.00853081
AK4 adenylate kinase 4 -0.00852332
NR1D2 nuclear receptor subfamily 1, group D, member 2 -0.00848925
PTBP3 polypyrimidine tract binding protein 3 -0.00845843
KIF1B kinesin family member 1B -0.0084435
TSPAN5 tetraspanin 5 -0.00843423
PRMT1 protein arginine methyltransferase 1 -0.0083915
KRCC1 lysine-rich coiled-coil 1 -0.00837142
CNTNAP2 contactin associated protein-like 2 -0.0083584
TNFRSF17 tumor necrosis factor receptor superfamily, member 17 -0.00834347
ME2 malic enzyme 2, NAD(+)-dependent, mitochondrial -0.00830071
GPR37 G protein-coupled receptor 37 (endothelin receptor type B-like) -0.00827671
TUBB2A tubulin, beta 2A class IIa -0.00826996
SET SET nuclear proto-oncogene -0.00819775
CCNG1 cyclin G1 -0.00818841
SLAMF7 SLAM family member 7 -0.00818772
ACTB actin, beta -0.00816705
STMN2 stathmin 2 -0.00815994
PBX1 pre-B-cell leukemia homeobox 1 -0.00811469
CDC42 cell division cycle 42 -0.00811047
CCR7 chemokine (C-C motif) receptor 7 -0.00809582
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 -0.00807577
TDRD7 tudor domain containing 7 -0.00806028
PNMA2 paraneoplastic Ma antigen 2 -0.00805796
GANAB glucosidase, alpha; neutral AB -0.00804771
PIGK phosphatidylinositol glycan anchor biosynthesis, class K -0.00804618
DLST dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) -0.00804468
ZSCAN18 zinc finger and SCAN domain containing 18 -0.00798157
SLA Src-like-adaptor -0.00796075
PRKCQ protein kinase C, theta -0.00794754
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 -0.0079366
CORO1A coronin, actin binding protein, 1A -0.00792966
CSF1 colony stimulating factor 1 (macrophage) -0.00792836
HAS2 hyaluronan synthase 2 -0.00792706
MAGED1 melanoma antigen family D1 -0.00790596
CD14 CD14 molecule -0.00790154
TPST1 tyrosylprotein sulfotransferase 1 -0.00788054
PLAGL1 pleiomorphic adenoma gene-like 1 -0.00787339
EIF3I eukaryotic translation initiation factor 3, subunit I -0.0078714
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) -0.00786175
TOX3 TOX high mobility group box family member 3 -0.00786169
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide -0.00784482
AKT3 v-akt murine thymoma viral oncogene homolog 3 -0.00784477
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9 -0.00784228
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) -0.00782314
TREM1 triggering receptor expressed on myeloid cells 1 -0.00780894
GPR183 G protein-coupled receptor 183 -0.00779706
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12 -0.00778828
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) -0.00778397
NFIL3 nuclear factor, interleukin 3 regulated -0.00778299
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1 -0.00776653
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) -0.00775553
ODAM odontogenic, ameloblast asssociated -0.00775215
SYNE3 spectrin repeat containing, nuclear envelope family member 3 -0.00774506
CD2 CD2 molecule -0.00773493
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) -0.00772561
CARMIL1 capping protein regulator and myosin 1 linker 1 -0.00770669
PTGER4 prostaglandin E receptor 4 (subtype EP4) -0.00770326
BTG2 BTG family, member 2 -0.00769044
FPR1 formyl peptide receptor 1 -0.00767962
SELPLG selectin P ligand -0.00767076
LMNB1 lamin B1 -0.00765957
FCN1 ficolin (collagen/fibrinogen domain containing) 1 -0.00765585
MMP8 matrix metallopeptidase 8 -0.00765334
DET1 de-etiolated homolog 1 (Arabidopsis) -0.00764027
FMO2 flavin containing monooxygenase 2 (non-functional) -0.00763935
GPI glucose-6-phosphate isomerase -0.00763577
ATP6V0E2 ATPase, H+ transporting V0 subunit e2 -0.00761257
AZU1 azurocidin 1 -0.0075982
PTPRD protein tyrosine phosphatase, receptor type, D -0.00758479
ARID4A AT rich interactive domain 4A (RBP1-like) -0.0075825
PRRG1 proline rich Gla (G-carboxyglutamic acid) 1 -0.00756818
KIAA0125 KIAA0125 -0.00756113
IL2RG interleukin 2 receptor, gamma -0.00755996
RTN1 reticulon 1 -0.00755844
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3 -0.00755753
MGAT2 mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase -0.00754989
RHOH ras homolog family member H -0.00753803
CDC20 cell division cycle 20 -0.00752755
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 -0.00752313
GLDC glycine dehydrogenase (decarboxylating) -0.00752158
RGS1 regulator of G-protein signaling 1 -0.00750552
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 -0.00748592
C3AR1 complement component 3a receptor 1 -0.00748016
SGCB sarcoglycan, beta (43kDa dystrophin-associated glycoprotein) -0.0074588
TRIP6 thyroid hormone receptor interactor 6 -0.00745453
ATP5F1C ATP synthase F1 subunit gamma -0.0074451
RECK reversion-inducing-cysteine-rich protein with kazal motifs -0.00744476
VCAN versican -0.00743302
ELF5 E74-like factor 5 (ets domain transcription factor) -0.00743124
GCA grancalcin, EF-hand calcium binding protein -0.00742034
MYH10 myosin, heavy chain 10, non-muscle -0.0074099
TLR7 toll-like receptor 7 -0.00740492
UQCRFS1 ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 -0.00738229
GPM6A glycoprotein M6A -0.00738101
SPP1 secreted phosphoprotein 1 -0.00737264
RIPOR2 RHO family interacting cell polarization regulator 2 -0.00737257
NPR3 natriuretic peptide receptor 3 -0.00732961
HCRTR1 hypocretin (orexin) receptor 1 -0.0073202
RGS4 regulator of G-protein signaling 4 -0.00730597
BAX BCL2-associated X protein -0.00729585
TEX10 testis expressed 10 -0.00729579
MAX MYC associated factor X -0.0072926
DUSP2 dual specificity phosphatase 2 -0.00728458
SATB2 SATB homeobox 2 -0.00726852
EIF5 eukaryotic translation initiation factor 5 -0.00725808
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) -0.00725694
GSPT2 G1 to S phase transition 2 -0.00724383
DNAJC7 DnaJ (Hsp40) homolog, subfamily C, member 7 -0.0072374
TNFAIP8 tumor necrosis factor, alpha-induced protein 8 -0.00723284
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -0.00722532
COL9A2 collagen, type IX, alpha 2 -0.00721854
RTP4 receptor (chemosensory) transporter protein 4 -0.00721639
MARCHF1 membrane associated ring-CH-type finger 1 -0.00718706
AGPS alkylglycerone phosphate synthase -0.00718648
ANP32B acidic (leucine-rich) nuclear phosphoprotein 32 family, member B -0.0071861
PLCB4 phospholipase C, beta 4 -0.00713481
CORO2B coronin, actin binding protein, 2B -0.00710771