CASP10 Gene Set

Dataset MSigDB Cancer Gene Co-expression Modules
Category transcriptomics
Type co-expressed gene
Description caspase 10, apoptosis-related cysteine peptidase|This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 3 and 7, and the protein itself is processed by caspase 8. Mutations in this gene are associated with type IIA autoimmune lymphoproliferative syndrome, non-Hodgkin lymphoma and gastric cancer. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Apr 2011] (NCBI Entrez Gene Database, 843)
External Link http://www.broadinstitute.org/gsea/msigdb/cards/MORF_CASP10
Similar Terms
Downloads & Tools

Genes

117 co-expressed genes for CASP10 from the MSigDB Cancer Gene Co-expression Modules dataset.

Symbol Name
ABCB10 ATP-binding cassette, sub-family B (MDR/TAP), member 10
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9
ABCC8 ATP-binding cassette, sub-family C (CFTR/MRP), member 8
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase)
ADCY3 adenylate cyclase 3
AOC4P amine oxidase, copper containing 4, pseudogene
AQP7 aquaporin 7
ARL3 ADP-ribosylation factor-like 3
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
BMP10 bone morphogenetic protein 10
BNIP1 BCL2/adenovirus E1B 19kDa interacting protein 1
C1ORF216 chromosome 1 open reading frame 216
CASP10 caspase 10, apoptosis-related cysteine peptidase
CELA2B chymotrypsin-like elastase family, member 2B
CFH complement factor H
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CRHR1 corticotropin releasing hormone receptor 1
CYP11A1 cytochrome P450, family 11, subfamily A, polypeptide 1
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
DNAJC16 DnaJ (Hsp40) homolog, subfamily C, member 16
DPT dermatopontin
DTX4 deltex 4, E3 ubiquitin ligase
ELAVL2 ELAV like neuron-specific RNA binding protein 2
EPHB2 EPH receptor B2
ERCC4 excision repair cross-complementation group 4
ESR1 estrogen receptor 1
FIG4 FIG4 phosphoinositide 5-phosphatase
FLT1 fms-related tyrosine kinase 1
FNTB farnesyltransferase, CAAX box, beta
GJB5 gap junction protein, beta 5, 31.1kDa
GLE1 GLE1 RNA export mediator
GNPAT glyceronephosphate O-acyltransferase
GPLD1 glycosylphosphatidylinositol specific phospholipase D1
GPR18 G protein-coupled receptor 18
GPR3 G protein-coupled receptor 3
GRIK5 glutamate receptor, ionotropic, kainate 5
HOXD4 homeobox D4
HSD17B3 hydroxysteroid (17-beta) dehydrogenase 3
HTR7 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled
IFT27 intraflagellar transport 27
IGKV7-3 immunoglobulin kappa variable 7-3 (pseudogene)
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
IL13 interleukin 13
IL16 interleukin 16
IVL involucrin
KCNA5 potassium channel, voltage gated shaker related subfamily A, member 5
KCNJ6 potassium channel, inwardly rectifying subfamily J, member 6
KLHL18 kelch-like family member 18
KRR1 KRR1, small subunit (SSU) processome component, homolog (yeast)
KRT33A keratin 33A, type I
KRT86 keratin 86, type II
LRRC48 leucine rich repeat containing 48
LY9 lymphocyte antigen 9
MAGEA9 melanoma antigen family A9
MC5R melanocortin 5 receptor
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MFN1 mitofusin 1
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
MSH3 mutS homolog 3
MSL3 male-specific lethal 3 homolog (Drosophila)
MSX1 msh homeobox 1
NEUROD2 neuronal differentiation 2
NF1 neurofibromin 1
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive
NOS2 nitric oxide synthase 2, inducible
NPFF neuropeptide FF-amide peptide precursor
NR1I2 nuclear receptor subfamily 1, group I, member 2
NTNG2 netrin G2
NXPE3 neurexophilin and PC-esterase domain family, member 3
OPLAH 5-oxoprolinase (ATP-hydrolysing)
OPRL1 opiate receptor-like 1
OSBP oxysterol binding protein
P2RY10 purinergic receptor P2Y, G-protein coupled, 10
PAX9 paired box 9
PAXIP1 PAX interacting (with transcription-activation domain) protein 1
PGM3 phosphoglucomutase 3
PIGB phosphatidylinositol glycan anchor biosynthesis, class B
PIGR polymeric immunoglobulin receptor
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
POU6F1 POU class 6 homeobox 1
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PVR poliovirus receptor
RAD51D RAD51 paralog D
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5
RREB1 ras responsive element binding protein 1
RXRG retinoid X receptor, gamma
SGPL1 sphingosine-1-phosphate lyase 1
SIM2 single-minded family bHLH transcription factor 2
SLC16A5 solute carrier family 16 (monocarboxylate transporter), member 5
SLC18A1 solute carrier family 18 (vesicular monoamine transporter), member 1
SLC22A6 solute carrier family 22 (organic anion transporter), member 6
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC33A1 solute carrier family 33 (acetyl-CoA transporter), member 1
SLC46A3 solute carrier family 46, member 3
SLC4A3 solute carrier family 4 (anion exchanger), member 3
SLC6A11 solute carrier family 6 (neurotransmitter transporter), member 11
SP140 SP140 nuclear body protein
STK17A serine/threonine kinase 17a
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
SULT4A1 sulfotransferase family 4A, member 1
TBC1D22A TBC1 domain family, member 22A
TBX19 T-box 19
TBX5 T-box 5
TFDP2 transcription factor Dp-2 (E2F dimerization partner 2)
TMEM11 transmembrane protein 11
TMPRSS6 transmembrane protease, serine 6
TRIM24 tripartite motif containing 24
TSSK2 testis-specific serine kinase 2
WBP4 WW domain binding protein 4
WT1 Wilms tumor 1
ZBTB22 zinc finger and BTB domain containing 22
ZBTB40 zinc finger and BTB domain containing 40
ZNF266 zinc finger protein 266
ZNF500 zinc finger protein 500
ZNF592 zinc finger protein 592