CASP2 Gene Set

Dataset MSigDB Cancer Gene Co-expression Modules
Category transcriptomics
Type co-expressed gene
Description caspase 2, apoptosis-related cysteine peptidase|This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Caspases mediate cellular apoptosis through the proteolytic cleavage of specific protein substrates. The encoded protein may function in stress-induced cell death pathways, cell cycle maintenance, and the suppression of tumorigenesis. Increased expression of this gene may play a role in neurodegenerative disorders including Alzheimer's disease, Huntington's disease and temporal lobe epilepsy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011] (NCBI Entrez Gene Database, 835)
External Link http://www.broadinstitute.org/gsea/msigdb/cards/MORF_CASP2
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Genes

126 co-expressed genes for CASP2 from the MSigDB Cancer Gene Co-expression Modules dataset.

Symbol Name
ACR acrosin
ADAM15 ADAM metallopeptidase domain 15
ADAMTSL2 ADAMTS-like 2
ADD2 adducin 2 (beta)
AGER advanced glycosylation end product-specific receptor
AMELX amelogenin, X-linked
ANKRD12 ankyrin repeat domain 12
ARSE arylsulfatase E (chondrodysplasia punctata 1)
B4GALT3 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3
BAZ2A bromodomain adjacent to zinc finger domain, 2A
BOD1L1 biorientation of chromosomes in cell division 1-like 1
CAMK2B calcium/calmodulin-dependent protein kinase II beta
CARD10 caspase recruitment domain family, member 10
CASP2 caspase 2, apoptosis-related cysteine peptidase
CCAR1 cell division cycle and apoptosis regulator 1
CNOT4 CCR4-NOT transcription complex, subunit 4
CNP 2',3'-cyclic nucleotide 3' phosphodiesterase
CNTN1 contactin 1
COMMD9 COMM domain containing 9
COQ10A coenzyme Q10 homolog A (S. cerevisiae)
CRAMP1L Crm, cramped-like (Drosophila)
CRCP CGRP receptor component
CRYBA4 crystallin, beta A4
CS citrate synthase
CXCR2 chemokine (C-X-C motif) receptor 2
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
DDX11 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11
DDX47 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47
DENND4A DENN/MADD domain containing 4A
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DHX37 DEAH (Asp-Glu-Ala-His) box polypeptide 37
DRG2 developmentally regulated GTP binding protein 2
EFNA3 ephrin-A3
EML3 echinoderm microtubule associated protein like 3
FAM189A2 family with sequence similarity 189, member A2
FAM189B family with sequence similarity 189, member B
FBXL20 F-box and leucine-rich repeat protein 20
FDXR ferredoxin reductase
FKBP15 FK506 binding protein 15, 133kDa
GHITM growth hormone inducible transmembrane protein
GPA33 glycoprotein A33 (transmembrane)
GPR161 G protein-coupled receptor 161
GPR35 G protein-coupled receptor 35
GPRIN2 G protein regulated inducer of neurite outgrowth 2
GSK3A glycogen synthase kinase 3 alpha
GTF2F1 general transcription factor IIF, polypeptide 1, 74kDa
H6PD hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
HMGXB3 HMG box domain containing 3
HSF4 heat shock transcription factor 4
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
IFT140 intraflagellar transport 140
IGHMBP2 immunoglobulin mu binding protein 2
IGSF9B immunoglobulin superfamily, member 9B
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
IRF2BP1 interferon regulatory factor 2 binding protein 1
ITGA10 integrin, alpha 10
KHNYN KH and NYN domain containing
KIAA0195 KIAA0195
KIF1C kinesin family member 1C
KMT2A lysine (K)-specific methyltransferase 2A
LMTK2 lemur tyrosine kinase 2
LSM12 LSM12 homolog (S. cerevisiae)
LTK leukocyte receptor tyrosine kinase
M6PR mannose-6-phosphate receptor (cation dependent)
MED17 mediator complex subunit 17
MEPCE methylphosphate capping enzyme
METTL17 methyltransferase like 17
MGAT1 mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
MMP25 matrix metallopeptidase 25
MPP2 membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)
MVK mevalonate kinase
MYL2 myosin, light chain 2, regulatory, cardiac, slow
NDST1 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
NFRKB nuclear factor related to kappaB binding protein
NTSR2 neurotensin receptor 2
NUDT3 nudix (nucleoside diphosphate linked moiety X)-type motif 3
ODF1 outer dense fiber of sperm tails 1
ORC1 origin recognition complex, subunit 1
P2RY11 purinergic receptor P2Y, G-protein coupled, 11
PAIP2B poly(A) binding protein interacting protein 2B
PAX8 paired box 8
PCBP3 poly(rC) binding protein 3
PDPK1 3-phosphoinositide dependent protein kinase 1
PFDN1 prefoldin subunit 1
PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
PIGB phosphatidylinositol glycan anchor biosynthesis, class B
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PKMYT1 protein kinase, membrane associated tyrosine/threonine 1
PKN2 protein kinase N2
PML promyelocytic leukemia
PNMT phenylethanolamine N-methyltransferase
PPP1R10 protein phosphatase 1, regulatory subunit 10
PRKCSH protein kinase C substrate 80K-H
PRPH peripherin
PSD4 pleckstrin and Sec7 domain containing 4
PTGER3 prostaglandin E receptor 3 (subtype EP3)
PTPN9 protein tyrosine phosphatase, non-receptor type 9
RAP1GAP2 RAP1 GTPase activating protein 2
RBM8A RNA binding motif protein 8A
RPA2 replication protein A2, 32kDa
RRP9 ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast)
S100PBP S100P binding protein
SIK3 SIK family kinase 3
SIN3A SIN3 transcription regulator family member A
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4
SLC22A24 solute carrier family 22, member 24
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
SPPL2B signal peptide peptidase like 2B
STAT5B signal transducer and activator of transcription 5B
TBC1D22B TBC1 domain family, member 22B
TCF7 transcription factor 7 (T-cell specific, HMG-box)
TCOF1 Treacher Collins-Franceschetti syndrome 1
TEFM transcription elongation factor, mitochondrial
THRAP3 thyroid hormone receptor associated protein 3
TPMT thiopurine S-methyltransferase
TRA2A transformer 2 alpha homolog (Drosophila)
TSPO2 translocator protein 2
TUB tubby bipartite transcription factor
USP19 ubiquitin specific peptidase 19
USP39 ubiquitin specific peptidase 39
VRK3 vaccinia related kinase 3
WNT10B wingless-type MMTV integration site family, member 10B
ZBED1 zinc finger, BED-type containing 1
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZNF337 zinc finger protein 337