CAST Gene Set

Dataset NURSA Protein-Protein Interactions
Category proteomics
Type interacting protein
Description calpastatin|The protein encoded by this gene is an endogenous calpain (calcium-dependent cysteine protease) inhibitor. It consists of an N-terminal domain L and four repetitive calpain-inhibition domains (domains 1-4), and it is involved in the proteolysis of amyloid precursor protein. The calpain/calpastatin system is involved in numerous membrane fusion events, such as neural vesicle exocytosis and platelet and red-cell aggregation. The encoded protein is also thought to affect the expression levels of genes encoding structural or regulatory proteins. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jun 2010] (NCBI Entrez Gene Database, 831)
External Link http://www.ncbi.nlm.nih.gov/gene/831
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Genes

4 interacting proteins for CAST from the NURSA Protein-Protein Interactions dataset.

Symbol Name Standardized Value
HIST1H2BB histone cluster 1, H2bb 0.477091
DDX19B DEAD (Asp-Glu-Ala-Asp) box polypeptide 19B 0.425882
ST13 suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) 0.414793
PPIL3 peptidylprolyl isomerase (cyclophilin)-like 3 0.400252