CAT Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description catalase|This gene encodes catalase, a key antioxidant enzyme in the bodies defense against oxidative stress. Catalase is a heme enzyme that is present in the peroxisome of nearly all aerobic cells. Catalase converts the reactive oxygen species hydrogen peroxide to water and oxygen and thereby mitigates the toxic effects of hydrogen peroxide. Oxidative stress is hypothesized to play a role in the development of many chronic or late-onset diseases such as diabetes, asthma, Alzheimer's disease, systemic lupus erythematosus, rheumatoid arthritis, and cancers. Polymorphisms in this gene have been associated with decreases in catalase activity but, to date, acatalasemia is the only disease known to be caused by this gene. [provided by RefSeq, Oct 2009] (NCBI Entrez Gene Database, 847)
External Link https://ncbi.nlm.nih.gov/gene/847
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Genes

498 genes differentially expressed following the CAT gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta 0.00747881
RPA3 replication protein A3, 14kDa 0.00650579
CDCA4 cell division cycle associated 4 0.00602639
GRB7 growth factor receptor-bound protein 7 0.00602068
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit 0.00581102
RGS1 regulator of G-protein signaling 1 0.00546318
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) 0.00546201
VCAM1 vascular cell adhesion molecule 1 0.00540901
JCHAIN joining chain of multimeric IgA and IgM 0.00537576
CLCA1 chloride channel accessory 1 0.00526046
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) 0.00517174
HOXB2 homeobox B2 0.00509827
BEX1 brain expressed, X-linked 1 0.00500552
TNC tenascin C 0.00489656
HMGB2 high mobility group box 2 0.00483013
TMEM14B transmembrane protein 14B 0.00482844
SCG5 secretogranin V 0.00475305
EVI2A ecotropic viral integration site 2A 0.00472946
KRT19 keratin 19, type I 0.00469655
CGRRF1 cell growth regulator with ring finger domain 1 0.00469125
CXCR4 chemokine (C-X-C motif) receptor 4 0.00465653
RPS4Y1 ribosomal protein S4, Y-linked 1 0.00461689
MEIS1 Meis homeobox 1 0.00458563
DCK deoxycytidine kinase 0.00449196
DEFB1 defensin, beta 1 0.00446988
NUSAP1 nucleolar and spindle associated protein 1 0.0044331
ZSCAN18 zinc finger and SCAN domain containing 18 0.00442816
CKS2 CDC28 protein kinase regulatory subunit 2 0.00440589
CDKN3 cyclin-dependent kinase inhibitor 3 0.00437392
ANPEP alanyl (membrane) aminopeptidase 0.00434724
BEX4 brain expressed, X-linked 4 0.00431685
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 0.00430659
TYMS thymidylate synthetase 0.00429213
RANBP1 RAN binding protein 1 0.00422584
CCNA2 cyclin A2 0.00417415
CMAHP cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene 0.00417331
NPY neuropeptide Y 0.00417077
ADAM28 ADAM metallopeptidase domain 28 0.00414517
CHN2 chimerin 2 0.00413421
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 0.00412785
CD69 CD69 molecule 0.00411491
GREM1 gremlin 1, DAN family BMP antagonist 0.00408412
ADAMDEC1 ADAM-like, decysin 1 0.00407839
ZWINT ZW10 interacting kinetochore protein 0.00404839
BAMBI BMP and activin membrane-bound inhibitor 0.00403349
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein 0.00402427
PCLAF PCNA clamp associated factor 0.00401755
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4 0.00401238
EAPP E2F-associated phosphoprotein 0.00399763
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated) 0.00399365
WDR61 WD repeat domain 61 0.00395359
BIK BCL2-interacting killer (apoptosis-inducing) 0.00395127
MUC2 mucin 2, oligomeric mucus/gel-forming 0.00387373
PRKACB protein kinase, cAMP-dependent, catalytic, beta 0.00387235
REG3A regenerating islet-derived 3 alpha 0.00386806
WNT5A wingless-type MMTV integration site family, member 5A 0.00384494
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha 0.00383943
SNRPG small nuclear ribonucleoprotein polypeptide G 0.0038186
LGALS13 lectin, galactoside-binding, soluble, 13 0.00380831
C1ORF54 chromosome 1 open reading frame 54 0.00377599
GAPDH glyceraldehyde-3-phosphate dehydrogenase 0.00376375
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1 0.00375579
SPINK1 serine peptidase inhibitor, Kazal type 1 0.00373125
CLCA4 chloride channel accessory 4 0.00372584
SEC23A Sec23 homolog A (S. cerevisiae) 0.00372023
TST thiosulfate sulfurtransferase (rhodanese) 0.00371374
CADPS2 Ca++-dependent secretion activator 2 0.00369648
NTS neurotensin 0.00368114
NIPSNAP2 nipsnap homolog 2 0.00367853
SSX2IP synovial sarcoma, X breakpoint 2 interacting protein 0.00366626
PRDX3 peroxiredoxin 3 0.00366583
CPVL carboxypeptidase, vitellogenic-like 0.00365597
ATF3 activating transcription factor 3 0.00365104
TXNDC9 thioredoxin domain containing 9 0.00364261
PRC1 protein regulator of cytokinesis 1 0.00363294
ADAM9 ADAM metallopeptidase domain 9 0.0036302
SLC44A4 solute carrier family 44, member 4 0.00362733
CEP55 centrosomal protein 55kDa 0.00360936
ITGA7 integrin, alpha 7 0.00359926
PPP1R3C protein phosphatase 1, regulatory subunit 3C 0.00358949
GATA2 GATA binding protein 2 0.00358635
COMMD8 COMM domain containing 8 0.00356344
FGFR3 fibroblast growth factor receptor 3 0.00356271
RARRES1 retinoic acid receptor responder (tazarotene induced) 1 0.00356214
GALC galactosylceramidase 0.00355413
VRK1 vaccinia related kinase 1 0.00355337
PBK PDZ binding kinase 0.00354821
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1 0.0035362
SMYD3 SET and MYND domain containing 3 0.00351818
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae) 0.00351716
MGAT2 mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase 0.00350167
H2AFV H2A histone family, member V 0.00349347
HPRT1 hypoxanthine phosphoribosyltransferase 1 0.00346665
EXOSC4 exosome component 4 0.00344676
NCAPD3 non-SMC condensin II complex, subunit D3 0.00343494
RPL39L ribosomal protein L39-like 0.0034291
DUSP2 dual specificity phosphatase 2 0.00342789
SLC26A3 solute carrier family 26 (anion exchanger), member 3 0.00342136
PLS1 plastin 1 0.00342022
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 0.00340737
DHRS9 dehydrogenase/reductase (SDR family) member 9 0.00340021
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 0.00339993
CAPZA2 capping protein (actin filament) muscle Z-line, alpha 2 0.00339929
SPARCL1 SPARC-like 1 (hevin) 0.00339756
TMEM38B transmembrane protein 38B 0.00339529
SLC26A2 solute carrier family 26 (anion exchanger), member 2 0.00338564
CYB5R4 cytochrome b5 reductase 4 0.00336082
TSPAN6 tetraspanin 6 0.00336041
ITGB3BP integrin beta 3 binding protein (beta3-endonexin) 0.00333283
GLCE glucuronic acid epimerase 0.00333035
CKAP2 cytoskeleton associated protein 2 0.0033292
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 0.00332882
TRPM4 transient receptor potential cation channel, subfamily M, member 4 0.0033224
CCL20 chemokine (C-C motif) ligand 20 0.00331785
TMEM106C transmembrane protein 106C 0.00331611
THBS1 thrombospondin 1 0.00331299
PCGF2 polycomb group ring finger 2 0.00331045
KLRB1 killer cell lectin-like receptor subfamily B, member 1 0.0033085
TPK1 thiamin pyrophosphokinase 1 0.00330254
TSPAN12 tetraspanin 12 0.00329287
CDK1 cyclin-dependent kinase 1 0.00329028
SRGN serglycin 0.00328467
WBP5 WW domain binding protein 5 0.00327353
RACGAP1 Rac GTPase activating protein 1 0.00327104
PPP3CB protein phosphatase 3, catalytic subunit, beta isozyme 0.00325924
MSH2 mutS homolog 2 0.00325477
RTN2 reticulon 2 0.00323722
NANOG Nanog homeobox 0.00322953
FKBP1B FK506 binding protein 1B, 12.6 kDa 0.00322212
TARDBP TAR DNA binding protein 0.00322017
REG1A regenerating islet-derived 1 alpha 0.00321817
RFC3 replication factor C (activator 1) 3, 38kDa 0.00320593
GUCY1B3 guanylate cyclase 1, soluble, beta 3 0.00319426
LGALS2 lectin, galactoside-binding, soluble, 2 0.00318558
GINS1 GINS complex subunit 1 (Psf1 homolog) 0.00318333
HMGN4 high mobility group nucleosomal binding domain 4 0.0031822
HSPA14 heat shock 70kDa protein 14 0.00316986
INSIG1 insulin induced gene 1 0.00316478
FAM13B family with sequence similarity 13, member B 0.0031598
NEK2 NIMA-related kinase 2 0.00315365
SMS spermine synthase 0.00314741
CENPM centromere protein M 0.00314552
RGS2 regulator of G-protein signaling 2 0.00314375
REG1B regenerating islet-derived 1 beta 0.00313517
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) 0.00313429
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1 0.00313328
PAK1IP1 PAK1 interacting protein 1 0.0031289
RAD54B RAD54 homolog B (S. cerevisiae) 0.00312673
HELLS helicase, lymphoid-specific 0.00312609
MCM6 minichromosome maintenance complex component 6 0.00312166
RMI1 RecQ mediated genome instability 1 0.0031205
NUDT11 nudix (nucleoside diphosphate linked moiety X)-type motif 11 0.00311355
NREP neuronal regeneration related protein 0.00311329
EEF1E1 eukaryotic translation elongation factor 1 epsilon 1 0.00309961
PDSS1 prenyl (decaprenyl) diphosphate synthase, subunit 1 0.00309715
RCN2 reticulocalbin 2, EF-hand calcium binding domain 0.00308837
C3ORF14 chromosome 3 open reading frame 14 0.00307771
PID1 phosphotyrosine interaction domain containing 1 0.00307189
AP1AR adaptor-related protein complex 1 associated regulatory protein 0.0030587
ATF1 activating transcription factor 1 0.00305217
MUC4 mucin 4, cell surface associated 0.00304959
SNCA synuclein, alpha (non A4 component of amyloid precursor) 0.0030485
RRM2 ribonucleotide reductase M2 0.00304755
MICALL2 MICAL-like 2 0.00302932
ADI1 acireductone dioxygenase 1 0.00301647
NME5 NME/NM23 family member 5 0.00300858
GSAP gamma-secretase activating protein 0.00300607
SALL2 spalt-like transcription factor 2 0.00299735
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1 0.00299478
GLOD4 glyoxalase domain containing 4 0.00299224
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) 0.00298972
SEPHS1 selenophosphate synthetase 1 0.00298175
TMEM106B transmembrane protein 106B 0.00297836
TGIF1 TGFB-induced factor homeobox 1 0.00297286
CREM cAMP responsive element modulator 0.00297286
REV1 REV1, polymerase (DNA directed) 0.0029579
NEIL3 nei endonuclease VIII-like 3 (E. coli) 0.00295551
TMX1 thioredoxin-related transmembrane protein 1 0.00293517
MCAM melanoma cell adhesion molecule 0.00293347
SLC25A14 solute carrier family 25 (mitochondrial carrier, brain), member 14 0.00292936
FANCI Fanconi anemia, complementation group I 0.00292304
RBM3 RNA binding motif (RNP1, RRM) protein 3 0.00292285
RFC4 replication factor C (activator 1) 4, 37kDa 0.00291872
PLAU plasminogen activator, urokinase 0.00291392
TMEM14A transmembrane protein 14A 0.00289186
NUP85 nucleoporin 85kDa 0.00288671
APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B 0.00288424
IDH3A isocitrate dehydrogenase 3 (NAD+) alpha 0.00287988
ATP2A3 ATPase, Ca++ transporting, ubiquitous 0.00287913
PPA2 pyrophosphatase (inorganic) 2 0.00287533
LPAR1 lysophosphatidic acid receptor 1 0.00287334
KRCC1 lysine-rich coiled-coil 1 0.00287157
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b 0.00287146
MOXD1 monooxygenase, DBH-like 1 0.00286847
ZNF124 zinc finger protein 124 0.0028544
PTPRD protein tyrosine phosphatase, receptor type, D 0.00285311
NAV3 neuron navigator 3 0.00285073
GPRASP1 G protein-coupled receptor associated sorting protein 1 0.00283255
ZNF217 zinc finger protein 217 0.00282959
CCNE2 cyclin E2 0.00282052
DPYSL3 dihydropyrimidinase-like 3 0.00281616
APOC2 apolipoprotein C-II 0.00281185
NEMP1 nuclear envelope integral membrane protein 1 0.00281162
MRS2 MRS2 magnesium transporter 0.00281159
PPIH peptidylprolyl isomerase H (cyclophilin H) 0.00281123
TMPO thymopoietin 0.00280999
DAXX death-domain associated protein 0.00280984
SLC35A3 solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 0.00280819
MAGEH1 melanoma antigen family H1 0.00280784
CD58 CD58 molecule 0.00279883
SKP1 S-phase kinase-associated protein 1 0.00279759
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney) 0.00279682
CKS1B CDC28 protein kinase regulatory subunit 1B 0.00279477
LPXN leupaxin 0.0027941
ATP8B4 ATPase, class I, type 8B, member 4 0.00278636
LGALS1 lectin, galactoside-binding, soluble, 1 0.00278461
HSPA13 heat shock protein 70kDa family, member 13 0.00278402
DHDDS dehydrodolichyl diphosphate synthase 0.00277499
ASRGL1 asparaginase like 1 0.00276758
MATR3 matrin 3 0.00276417
ARID4A AT rich interactive domain 4A (RBP1-like) 0.00276097
ENPP4 ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative) 0.00275952
RARRES2 retinoic acid receptor responder (tazarotene induced) 2 0.00275583
NDUFB5 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa 0.00275532
ZDHHC13 zinc finger, DHHC-type containing 13 0.00274634
MCOLN1 mucolipin 1 0.00274536
RPS5 ribosomal protein S5 0.00274141
SPC25 SPC25, NDC80 kinetochore complex component 0.00273867
H2AZ1 H2A.Z variant histone 1 0.00273672
LACTB2 lactamase, beta 2 0.00273635
ZBTB18 zinc finger and BTB domain containing 18 0.00273395
IL1R1 interleukin 1 receptor, type I 0.00271787
BIRC5 baculoviral IAP repeat containing 5 0.00271625
COPS4 COP9 signalosome subunit 4 0.00271408
GMNN geminin, DNA replication inhibitor 0.00270705
DDX50 DEAD (Asp-Glu-Ala-Asp) box polypeptide 50 0.00269785
KIF11 kinesin family member 11 0.0026895
STMN1 stathmin 1 0.00268882
NR5A2 nuclear receptor subfamily 5, group A, member 2 0.00268489
GNE glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase 0.00268122
CENPX centromere protein X 0.00267741
LSM2 LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae) 0.00267672
COL4A5 collagen, type IV, alpha 5 0.00267564
ADGRG6 adhesion G protein-coupled receptor G6 0.00267003
LYZ lysozyme 0.00266882
PDE4B phosphodiesterase 4B, cAMP-specific 0.0026644
NDN necdin, melanoma antigen (MAGE) family member 0.00266231
TBX3 T-box 3 0.00266192
SOCS5 suppressor of cytokine signaling 5 0.00265483
MATN2 matrilin 2 0.00265332

decreased expression

Symbol Name Standardized Value
KRT14 keratin 14, type I -0.00891602
ISG15 ISG15 ubiquitin-like modifier -0.00748344
MKNK2 MAP kinase interacting serine/threonine kinase 2 -0.007364
MX1 MX dynamin-like GTPase 1 -0.00721262
IFI44L interferon-induced protein 44-like -0.00717508
CAT catalase -0.00684306
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 -0.00670488
IRF7 interferon regulatory factor 7 -0.00669273
SLPI secretory leukocyte peptidase inhibitor -0.00654188
LTF lactotransferrin -0.00653695
IFI27 interferon, alpha-inducible protein 27 -0.00618219
GNAS GNAS complex locus -0.00592177
IFITM1 interferon induced transmembrane protein 1 -0.00574862
RFTN1 raftlin, lipid raft linker 1 -0.00571682
IFITM2 interferon induced transmembrane protein 2 -0.00563678
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 -0.0055897
RBM34 RNA binding motif protein 34 -0.00557718
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa -0.00550882
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa -0.005459
AQP3 aquaporin 3 (Gill blood group) -0.00544614
SCGB2A2 secretoglobin, family 2A, member 2 -0.00538481
ZNF91 zinc finger protein 91 -0.00522543
SEPTIN9 septin 9 -0.00521232
IFI6 interferon, alpha-inducible protein 6 -0.00519265
FOLR1 folate receptor 1 (adult) -0.0051778
HMOX1 heme oxygenase 1 -0.00516621
IFITM3 interferon induced transmembrane protein 3 -0.00513665
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B -0.004976
KRT17 keratin 17, type I -0.00497136
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5 -0.00490267
MAGEA3 melanoma antigen family A3 -0.00486255
SCGB1D2 secretoglobin, family 1D, member 2 -0.00483925
AUTS2 autism susceptibility candidate 2 -0.0048365
PON3 paraoxonase 3 -0.00482189
DUSP4 dual specificity phosphatase 4 -0.00475777
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 -0.0047563
FXYD5 FXYD domain containing ion transport regulator 5 -0.00472167
PLIN2 perilipin 2 -0.00470702
DSP desmoplakin -0.00468429
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa -0.00463481
SLC22A18 solute carrier family 22, member 18 -0.00463015
KRT5 keratin 5, type II -0.00462062
SYNE3 spectrin repeat containing, nuclear envelope family member 3 -0.00458057
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 -0.00456651
GPRC5A G protein-coupled receptor, class C, group 5, member A -0.00449742
USP47 ubiquitin specific peptidase 47 -0.00446753
SP110 SP110 nuclear body protein -0.00444679
SIDT2 SID1 transmembrane family, member 2 -0.00442584
EPS8L2 EPS8-like 2 -0.0044021
ACTN4 actinin, alpha 4 -0.00437477
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 -0.00435717
IFIT3 interferon-induced protein with tetratricopeptide repeats 3 -0.00435119
ZC3HAV1 zinc finger CCCH-type, antiviral 1 -0.00432936
USP18 ubiquitin specific peptidase 18 -0.00430249
SCNN1A sodium channel, non voltage gated 1 alpha subunit -0.00427705
ZIC1 Zic family member 1 -0.00426464
LIMCH1 LIM and calponin homology domains 1 -0.00426181
PCDH9 protocadherin 9 -0.0042527
MVP major vault protein -0.00424563
PSMF1 proteasome (prosome, macropain) inhibitor subunit 1 (PI31) -0.00424228
LRP5 low density lipoprotein receptor-related protein 5 -0.00421349
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic) -0.00420688
GAB2 GRB2-associated binding protein 2 -0.00420195
PRAME preferentially expressed antigen in melanoma -0.00417923
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2 -0.00417595
TNNC1 troponin C type 1 (slow) -0.00415461
TGFBI transforming growth factor, beta-induced, 68kDa -0.00414018
CDH1 cadherin 1, type 1, E-cadherin (epithelial) -0.00404336
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II -0.00403738
ITGBL1 integrin, beta-like 1 (with EGF-like repeat domains) -0.00400949
RRAS2 related RAS viral (r-ras) oncogene homolog 2 -0.00395251
RSAD2 radical S-adenosyl methionine domain containing 2 -0.00393359
KRT1 keratin 1, type II -0.00392497
SEC62 SEC62 homolog (S. cerevisiae) -0.003909
JUP junction plakoglobin -0.00388821
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 -0.003842
DENND5A DENN/MADD domain containing 5A -0.00384116
EIF3F eukaryotic translation initiation factor 3, subunit F -0.00383118
TSPAN4 tetraspanin 4 -0.0038164
TALDO1 transaldolase 1 -0.0038119
ADAR adenosine deaminase, RNA-specific -0.00372799
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta -0.00372548
PODXL podocalyxin-like -0.00370067
DLST dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) -0.00369823
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 -0.00369183
LAMB3 laminin, beta 3 -0.00369001
ANO1 anoctamin 1, calcium activated chloride channel -0.00368931
IL32 interleukin 32 -0.00368341
DUSP7 dual specificity phosphatase 7 -0.00368025
IFIH1 interferon induced with helicase C domain 1 -0.00366706
KLF5 Kruppel-like factor 5 (intestinal) -0.00366315
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 -0.00366187
MLXIP MLX interacting protein -0.00365316
RAB8A RAB8A, member RAS oncogene family -0.00365012
CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase -0.00364456
LAMP1 lysosomal-associated membrane protein 1 -0.00364383
GPI glucose-6-phosphate isomerase -0.00363961
IFI44 interferon-induced protein 44 -0.00363136
PIP prolactin-induced protein -0.00361754
TRIM29 tripartite motif containing 29 -0.00361329
WNK1 WNK lysine deficient protein kinase 1 -0.00361244
PLXND1 plexin D1 -0.00360756
PPFIA1 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 -0.00360428
SRPRA SRP receptor subunit alpha -0.00359223
FBLN5 fibulin 5 -0.00358479
LEF1 lymphoid enhancer-binding factor 1 -0.00357185
AIM2 absent in melanoma 2 -0.00355795
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1 -0.00354799
PUM1 pumilio RNA-binding family member 1 -0.00353553
AEBP1 AE binding protein 1 -0.00353538
SORBS2 sorbin and SH3 domain containing 2 -0.00353309
NCOR2 nuclear receptor corepressor 2 -0.00352285
SAMD9 sterile alpha motif domain containing 9 -0.00352089
S100A7 S100 calcium binding protein A7 -0.00351722
LY6E lymphocyte antigen 6 complex, locus E -0.00350587
PLS3 plastin 3 -0.00350001
PLPP3 phospholipid phosphatase 3 -0.00349598
POLR2L polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa -0.00349163
ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 -0.00345951
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1 -0.00345782
COG7 component of oligomeric golgi complex 7 -0.00343471
XAF1 XIAP associated factor 1 -0.003421
IGF2R insulin-like growth factor 2 receptor -0.00341786
TENT5A terminal nucleotidyltransferase 5A -0.00340817
GPM6B glycoprotein M6B -0.00339829
TMCC1 transmembrane and coiled-coil domain family 1 -0.0033979
ERBB2 erb-b2 receptor tyrosine kinase 2 -0.0033962
CTTN cortactin -0.00337244
AP2A2 adaptor-related protein complex 2, alpha 2 subunit -0.0033394
TPP1 tripeptidyl peptidase I -0.00333712
ZMYND8 zinc finger, MYND-type containing 8 -0.00332717
S100A8 S100 calcium binding protein A8 -0.00331619
NKX2-1 NK2 homeobox 1 -0.00330445
MARK4 MAP/microtubule affinity-regulating kinase 4 -0.00330368
TRIM44 tripartite motif containing 44 -0.00328473
S100A2 S100 calcium binding protein A2 -0.00328395
SCRIB scribbled planar cell polarity protein -0.00327888
SOX9 SRY (sex determining region Y)-box 9 -0.00327848
ARG1 arginase 1 -0.00327787
PDLIM2 PDZ and LIM domain 2 (mystique) -0.00327749
HIRA histone cell cycle regulator -0.00326137
RIC8A RIC8 guanine nucleotide exchange factor A -0.00325996
BMP4 bone morphogenetic protein 4 -0.00325394
RBPJ recombination signal binding protein for immunoglobulin kappa J region -0.00324472
BRD4 bromodomain containing 4 -0.0032443
VCL vinculin -0.00323897
CLIC3 chloride intracellular channel 3 -0.00323456
RNASET2 ribonuclease T2 -0.00322526
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) -0.00322202
CRABP1 cellular retinoic acid binding protein 1 -0.00321557
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) -0.00320553
VGLL4 vestigial-like family member 4 -0.00318785
DNAJC7 DnaJ (Hsp40) homolog, subfamily C, member 7 -0.00318737
CDA cytidine deaminase -0.00316984
WARS1 tryptophanyl-tRNA synthetase 1 -0.00316269
AK1 adenylate kinase 1 -0.00316199
ADGRF5 adhesion G protein-coupled receptor F5 -0.00316062
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 -0.00315988
C1ORF56 chromosome 1 open reading frame 56 -0.00315498
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1 -0.00315392
MXRA5 matrix-remodelling associated 5 -0.00315362
RNF167 ring finger protein 167 -0.00314719
MSX1 msh homeobox 1 -0.0031416
TACSTD2 tumor-associated calcium signal transducer 2 -0.00313541
NRN1 neuritin 1 -0.0031311
KDM3A lysine (K)-specific demethylase 3A -0.00313052
TMEM45A transmembrane protein 45A -0.00312936
YBX3 Y box binding protein 3 -0.00312452
VPREB1 pre-B lymphocyte 1 -0.00312438
ECM1 extracellular matrix protein 1 -0.00312048
LAMB1 laminin, beta 1 -0.00311925
S100P S100 calcium binding protein P -0.00311464
CAPNS1 calpain, small subunit 1 -0.00311167
NR2F6 nuclear receptor subfamily 2, group F, member 6 -0.00310951
KRT7 keratin 7, type II -0.0031066
TGFBR3 transforming growth factor, beta receptor III -0.00309923
DCN decorin -0.00309161
CARM1 coactivator-associated arginine methyltransferase 1 -0.00308797
LRP4 low density lipoprotein receptor-related protein 4 -0.00308069
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1 -0.00307245
TNIP1 TNFAIP3 interacting protein 1 -0.00307032
PAM peptidylglycine alpha-amidating monooxygenase -0.00306883
ADORA2B adenosine A2b receptor -0.00306743
MAGEA12 melanoma antigen family A12 -0.00305165
CHERP calcium homeostasis endoplasmic reticulum protein -0.00305082
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -0.00304882
ESF1 ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae) -0.00303823
TUBB2B tubulin, beta 2B class IIb -0.00303659
ACTN1 actinin, alpha 1 -0.00303642
CKAP4 cytoskeleton-associated protein 4 -0.00303175
APOD apolipoprotein D -0.00302522
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5 -0.00301646
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) -0.00299619
CD81 CD81 molecule -0.00299574
SHFL shiftless antiviral inhibitor of ribosomal frameshifting -0.00299506
AZGP1 alpha-2-glycoprotein 1, zinc-binding -0.00299212
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa -0.00298766
OASL 2'-5'-oligoadenylate synthetase-like -0.00298724
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5 -0.00296628
CD14 CD14 molecule -0.00296552
KRT6A keratin 6A, type II -0.00296281
ITGB4 integrin, beta 4 -0.00295937
PLXNA1 plexin A1 -0.0029562
SIRT3 sirtuin 3 -0.00295599
ADGRE5 adhesion G protein-coupled receptor E5 -0.00295469
TFG TRK-fused gene -0.00294846
CA12 carbonic anhydrase XII -0.00294317
TGFA transforming growth factor, alpha -0.00294187
FGFR1 fibroblast growth factor receptor 1 -0.00293925
LARP1 La ribonucleoprotein domain family, member 1 -0.00293253
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 -0.00292838
CX3CL1 chemokine (C-X3-C motif) ligand 1 -0.00292803
THBD thrombomodulin -0.00292799
TNS3 tensin 3 -0.00292387
UBE2L6 ubiquitin-conjugating enzyme E2L 6 -0.00291879
INHBA inhibin, beta A -0.00291752
NUCB2 nucleobindin 2 -0.00291492
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) -0.00291355
EIF4H eukaryotic translation initiation factor 4H -0.00291062
NAP1L4 nucleosome assembly protein 1-like 4 -0.00290397
BST2 bone marrow stromal cell antigen 2 -0.00289377
CLEC2B C-type lectin domain family 2, member B -0.00289203
MYO6 myosin VI -0.0028861
MX2 MX dynamin-like GTPase 2 -0.00288133
CTR9 CTR9, Paf1/RNA polymerase II complex component -0.00287843
PPL periplakin -0.00287769
ARPC1B actin related protein 2/3 complex, subunit 1B, 41kDa -0.00287762
POLDIP2 polymerase (DNA-directed), delta interacting protein 2 -0.00286813
SEC14L1 SEC14-like 1 (S. cerevisiae) -0.00286114
IRF9 interferon regulatory factor 9 -0.00285678
PARP12 poly (ADP-ribose) polymerase family, member 12 -0.00285358
DRAP1 DR1-associated protein 1 (negative cofactor 2 alpha) -0.00285229
ARPP19 cAMP-regulated phosphoprotein, 19kDa -0.00285017
MEF2C myocyte enhancer factor 2C -0.00283431
PEBP1 phosphatidylethanolamine binding protein 1 -0.00283155
VTCN1 V-set domain containing T cell activation inhibitor 1 -0.00283032
GBP2 guanylate binding protein 2, interferon-inducible -0.00282953
BGN biglycan -0.00282809
CRABP2 cellular retinoic acid binding protein 2 -0.00281959
COCH cochlin -0.00281842
TXNRD1 thioredoxin reductase 1 -0.00281603
MGRN1 mahogunin ring finger 1, E3 ubiquitin protein ligase -0.00281376
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -0.00281165
F5 coagulation factor V (proaccelerin, labile factor) -0.0028113
IGFBP4 insulin-like growth factor binding protein 4 -0.00280947
MPRIP myosin phosphatase Rho interacting protein -0.00280617
OXA1L oxidase (cytochrome c) assembly 1-like -0.00280085
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 -0.00280007