CAV1 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description caveolin 1, caveolae protein, 22kDa|The scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 mitogen-activated kinase cascade. Caveolin 1 and caveolin 2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. Mutations in this gene have been associated with Berardinelli-Seip congenital lipodystrophy. Alternatively spliced transcripts encode alpha and beta isoforms of caveolin 1.[provided by RefSeq, Mar 2010] (NCBI Entrez Gene Database, 857)
External Link https://ncbi.nlm.nih.gov/gene/857
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Genes

498 genes differentially expressed following the CAV1 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 0.025928
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 0.0180139
METRN meteorin, glial cell differentiation regulator 0.0168673
HEY1 hes-related family bHLH transcription factor with YRPW motif 1 0.0166358
AQP3 aquaporin 3 (Gill blood group) 0.0158426
RGCC regulator of cell cycle 0.0156468
MAGEA3 melanoma antigen family A3 0.0150517
NEBL nebulette 0.013979
CCN2 cellular communication network factor 2 0.0129993
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 0.0125174
CARMIL1 capping protein regulator and myosin 1 linker 1 0.011994
IVNS1ABP influenza virus NS1A binding protein 0.0118292
GPM6B glycoprotein M6B 0.0115798
NEDD9 neural precursor cell expressed, developmentally down-regulated 9 0.0114724
S100P S100 calcium binding protein P 0.0111845
LPAR6 lysophosphatidic acid receptor 6 0.0111834
MARCKSL1 MARCKS-like 1 0.0111134
KYNU kynureninase 0.0108005
RCAN1 regulator of calcineurin 1 0.0107283
WFDC1 WAP four-disulfide core domain 1 0.0105657
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 0.0105364
RARRES1 retinoic acid receptor responder (tazarotene induced) 1 0.0104691
SLC39A8 solute carrier family 39 (zinc transporter), member 8 0.0104646
DKK1 dickkopf WNT signaling pathway inhibitor 1 0.0104635
CX3CL1 chemokine (C-X3-C motif) ligand 1 0.0104214
SCNN1A sodium channel, non voltage gated 1 alpha subunit 0.0104155
PRKCA protein kinase C, alpha 0.010328
NID1 nidogen 1 0.0103039
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2 0.0101716
PDE4B phosphodiesterase 4B, cAMP-specific 0.0101397
FSCN1 fascin actin-bundling protein 1 0.00987205
MGP matrix Gla protein 0.00980201
FZD6 frizzled class receptor 6 0.00978166
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 0.00975107
MSLN mesothelin 0.00960094
MAGEA12 melanoma antigen family A12 0.00950421
KRT81 keratin 81, type II 0.00950348
SIK1 salt-inducible kinase 1 0.00937497
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.009362
GJA1 gap junction protein, alpha 1, 43kDa 0.0092879
S100A7 S100 calcium binding protein A7 0.00926079
TFDP1 transcription factor Dp-1 0.00919811
NHS Nance-Horan syndrome (congenital cataracts and dental anomalies) 0.0091875
EDNRB endothelin receptor type B 0.00916623
INHBB inhibin, beta B 0.00912837
MAL mal, T-cell differentiation protein 0.00911084
GIMAP6 GTPase, IMAP family member 6 0.00910572
LAMB1 laminin, beta 1 0.00909957
JPT2 Jupiter microtubule associated homolog 2 0.00896321
TPPP3 tubulin polymerization-promoting protein family member 3 0.00892649
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) 0.00889439
LAMP3 lysosomal-associated membrane protein 3 0.00889015
VEGFA vascular endothelial growth factor A 0.00884542
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) 0.00881916
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 0.00880287
LMCD1 LIM and cysteine-rich domains 1 0.0087314
MCAM melanoma cell adhesion molecule 0.00872082
TUBB2B tubulin, beta 2B class IIb 0.00871679
PLK1 polo-like kinase 1 0.00871237
ARHGAP15 Rho GTPase activating protein 15 0.00870841
INAVA innate immunity activator 0.0086869
SGPP1 sphingosine-1-phosphate phosphatase 1 0.00867459
ATF3 activating transcription factor 3 0.00864997
HBEGF heparin-binding EGF-like growth factor 0.00861866
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.00861365
BGN biglycan 0.00860793
LXN latexin 0.00860604
PAN2 PAN2 poly(A) specific ribonuclease subunit 0.00860077
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 0.00859956
CYTL1 cytokine-like 1 0.00859824
ADGRF5 adhesion G protein-coupled receptor F5 0.00855834
CLEC2B C-type lectin domain family 2, member B 0.00851214
S100B S100 calcium binding protein B 0.00848071
HSPD1 heat shock 60kDa protein 1 (chaperonin) 0.00847239
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 0.00844939
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein 0.00841435
CST1 cystatin SN 0.00833877
ALCAM activated leukocyte cell adhesion molecule 0.00828802
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1 0.00827259
WWTR1 WW domain containing transcription regulator 1 0.00827147
POSTN periostin, osteoblast specific factor 0.00826739
TFRC transferrin receptor 0.00820776
ACTG2 actin, gamma 2, smooth muscle, enteric 0.00818191
PLLP plasmolipin 0.00815852
ACSF2 acyl-CoA synthetase family member 2 0.0081555
FOSB FBJ murine osteosarcoma viral oncogene homolog B 0.00813018
IFI44 interferon-induced protein 44 0.00812144
RNASET2 ribonuclease T2 0.00811921
SYNM synemin, intermediate filament protein 0.00810925
GRB7 growth factor receptor-bound protein 7 0.00807179
CD93 CD93 molecule 0.00805448
MAP2K6 mitogen-activated protein kinase kinase 6 0.00803847
MAN1A1 mannosidase, alpha, class 1A, member 1 0.00803506
CD96 CD96 molecule 0.00802931
APOLD1 apolipoprotein L domain containing 1 0.00799016
CXADR coxsackie virus and adenovirus receptor 0.00796254
RANBP9 RAN binding protein 9 0.00784592
RPS4Y1 ribosomal protein S4, Y-linked 1 0.00783994
NME4 NME/NM23 nucleoside diphosphate kinase 4 0.00782213
PIR pirin (iron-binding nuclear protein) 0.00776765
NELL2 NEL-like 2 (chicken) 0.00769794
MAT2A methionine adenosyltransferase II, alpha 0.00769398
NR4A2 nuclear receptor subfamily 4, group A, member 2 0.0076597
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B 0.00765361
BAMBI BMP and activin membrane-bound inhibitor 0.00764854
ADD3 adducin 3 (gamma) 0.00764525
GPX2 glutathione peroxidase 2 0.0076342
FRZB frizzled-related protein 0.00761889
DHRS3 dehydrogenase/reductase (SDR family) member 3 0.00758441
MYO1B myosin IB 0.0075714
CCNA2 cyclin A2 0.0075549
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2 0.00754631
ALDH5A1 aldehyde dehydrogenase 5 family, member A1 0.00752603
SELENBP1 selenium binding protein 1 0.00752048
CFI complement factor I 0.00749556
ACTA2 actin, alpha 2, smooth muscle, aorta 0.00749122
MMP10 matrix metallopeptidase 10 0.00748774
EFNA1 ephrin-A1 0.00745263
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein 0.00742075
PPARG peroxisome proliferator-activated receptor gamma 0.00741158
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3 0.0073401
ABAT 4-aminobutyrate aminotransferase 0.00732283
PDE4D phosphodiesterase 4D, cAMP-specific 0.00731749
CHKB choline kinase beta 0.00729182
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2 0.00728393
CARHSP1 calcium regulated heat stable protein 1, 24kDa 0.00727395
HCRT hypocretin (orexin) neuropeptide precursor 0.0072624
HOXB7 homeobox B7 0.00726159
EMP2 epithelial membrane protein 2 0.00726062
QPRT quinolinate phosphoribosyltransferase 0.00723199
PPT1 palmitoyl-protein thioesterase 1 0.00722227
RNASE6 ribonuclease, RNase A family, k6 0.00719894
FAR2 fatty acyl CoA reductase 2 0.00717093
GPM6A glycoprotein M6A 0.00715716
SMAD6 SMAD family member 6 0.00711594
PODXL podocalyxin-like 0.00710733
CHD7 chromodomain helicase DNA binding protein 7 0.00710724
TOB1 transducer of ERBB2, 1 0.00710073
CDH5 cadherin 5, type 2 (vascular endothelium) 0.00707297
GMFG glia maturation factor, gamma 0.00703597
PTGER4 prostaglandin E receptor 4 (subtype EP4) 0.00702253
SYNPO synaptopodin 0.00699981
C9ORF3 chromosome 9 open reading frame 3 0.00699285
SORBS1 sorbin and SH3 domain containing 1 0.00698319
REEP5 receptor accessory protein 5 0.00694854
SCD stearoyl-CoA desaturase (delta-9-desaturase) 0.00691927
DIP2C DIP2 disco-interacting protein 2 homolog C (Drosophila) 0.00691714
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 0.00690636
EPCAM epithelial cell adhesion molecule 0.00689066
FOLR1 folate receptor 1 (adult) 0.00688485
PLS3 plastin 3 0.00687292
ADGRG6 adhesion G protein-coupled receptor G6 0.00686475
MECOM MDS1 and EVI1 complex locus 0.00686128
RNF167 ring finger protein 167 0.00685855
COL5A2 collagen, type V, alpha 2 0.00684781
PRAME preferentially expressed antigen in melanoma 0.00684609
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein 0.0068338
TSPAN7 tetraspanin 7 0.00682001
IQCK IQ motif containing K 0.00681732
FAM107A family with sequence similarity 107, member A 0.00681586
ZDHHC14 zinc finger, DHHC-type containing 14 0.0068128
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1 0.00680881
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5 0.00680754
BPHL biphenyl hydrolase-like (serine hydrolase) 0.00680091
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 0.00679277
LY75 lymphocyte antigen 75 0.00678715
MYRF myelin regulatory factor 0.00677943
ACKR3 atypical chemokine receptor 3 0.00677847
FCGBP Fc fragment of IgG binding protein 0.00677344
LAMA4 laminin, alpha 4 0.00676779
ANGPT2 angiopoietin 2 0.00676389
PTPRZ1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1 0.00673989
MMP12 matrix metallopeptidase 12 0.00671894
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific ) 0.00671782
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 0.00669144
VIL1 villin 1 0.00667859
PSAT1 phosphoserine aminotransferase 1 0.00662742
MARCKS myristoylated alanine-rich protein kinase C substrate 0.00661194
CALB1 calbindin 1, 28kDa 0.00659813
PRSS21 protease, serine, 21 (testisin) 0.00657902
RIOX2 ribosomal oxygenase 2 0.00655198
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 0.00651922
RGS1 regulator of G-protein signaling 1 0.00650933
ACSL5 acyl-CoA synthetase long-chain family member 5 0.00650842
HSPG2 heparan sulfate proteoglycan 2 0.00647933
LRP4 low density lipoprotein receptor-related protein 4 0.00646139
FABP1 fatty acid binding protein 1, liver 0.00645357
SRGN serglycin 0.00644305
SLC4A1 solute carrier family 4 (anion exchanger), member 1 (Diego blood group) 0.00642737
ITM2C integral membrane protein 2C 0.00639764
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor) 0.00639257
MDFIC MyoD family inhibitor domain containing 0.00638934
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 0.00637501
FABP4 fatty acid binding protein 4, adipocyte 0.00634158
CASP10 caspase 10, apoptosis-related cysteine peptidase 0.00631702
ACAA2 acetyl-CoA acyltransferase 2 0.00631252
LZTS3 leucine zipper, putative tumor suppressor family member 3 0.00630675
ZFP36 ZFP36 ring finger protein 0.00627311
GCH1 GTP cyclohydrolase 1 0.00627005
SELE selectin E 0.00625904
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) 0.00622851
GALC galactosylceramidase 0.00622272
ZNF395 zinc finger protein 395 0.00621489
GSS glutathione synthetase 0.00620828
SAT1 spermidine/spermine N1-acetyltransferase 1 0.00620792
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2 0.00619838
FAM198B family with sequence similarity 198, member B 0.00617543
PIP5K1B phosphatidylinositol-4-phosphate 5-kinase, type I, beta 0.00614559
RBMS1 RNA binding motif, single stranded interacting protein 1 0.00613218
CD3D CD3d molecule, delta (CD3-TCR complex) 0.00612867
GIPC2 GIPC PDZ domain containing family, member 2 0.00612428
EDN1 endothelin 1 0.00612097
PROM1 prominin 1 0.00611752
XCL1 chemokine (C motif) ligand 1 0.00610909
FERMT1 fermitin family member 1 0.00610713
MLF1 myeloid leukemia factor 1 0.00610143
ALDH1A3 aldehyde dehydrogenase 1 family, member A3 0.00609825
BTG3 BTG family, member 3 0.00608553
CCT2 chaperonin containing TCP1, subunit 2 (beta) 0.00608363
CEBPD CCAAT/enhancer binding protein (C/EBP), delta 0.00607835
PPM1H protein phosphatase, Mg2+/Mn2+ dependent, 1H 0.00607438
PLVAP plasmalemma vesicle associated protein 0.00607099
MMD monocyte to macrophage differentiation-associated 0.00606761
TMEM204 transmembrane protein 204 0.00606013
EXOC5 exocyst complex component 5 0.00605821
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5 0.00604925
C1QBP complement component 1, q subcomponent binding protein 0.00603315
ANOS1 anosmin 1 0.00601599
CFAP20 cilia and flagella associated protein 20 0.00600567
ALDH3B1 aldehyde dehydrogenase 3 family, member B1 0.00600102
DDX11 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 0.00599381
MUC16 mucin 16, cell surface associated 0.00597214
PLIN2 perilipin 2 0.00596027
FEZ1 fasciculation and elongation protein zeta 1 (zygin I) 0.00595938
CRELD2 cysteine-rich with EGF-like domains 2 0.00594251
PRKD3 protein kinase D3 0.0059366
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) 0.00593177
CADM1 cell adhesion molecule 1 0.00593047
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 0.00592867
ACAT2 acetyl-CoA acetyltransferase 2 0.00591906
IL27RA interleukin 27 receptor, alpha 0.00591441
GALNT2 polypeptide N-acetylgalactosaminyltransferase 2 0.0059124
CEMIP cell migration inducing protein, hyaluronan binding 0.00590627
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme 0.00590239
BRD7 bromodomain containing 7 0.0059004
SEMA3F sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F 0.00589971
ADIRF adipogenesis regulatory factor 0.00588649
ATP6V0A4 ATPase, H+ transporting, lysosomal V0 subunit a4 0.00588478

decreased expression

Symbol Name Standardized Value
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) -0.0265539
MBOAT7 membrane bound O-acyltransferase domain containing 7 -0.0180618
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -0.016581
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) -0.0155071
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta -0.0144605
SSBP2 single-stranded DNA binding protein 2 -0.0124061
PDGFRL platelet-derived growth factor receptor-like -0.0118647
XIC X chromosome inactivation center -0.0112596
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding) -0.011019
COPS7A COP9 signalosome subunit 7A -0.010832
LDOC1 leucine zipper, down-regulated in cancer 1 -0.0106321
FSD1 fibronectin type III and SPRY domain containing 1 -0.0104176
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) -0.0101278
DAPK1 death-associated protein kinase 1 -0.0100785
C10ORF10 chromosome 10 open reading frame 10 -0.0100002
POLR2J2 polymerase (RNA) II (DNA directed) polypeptide J2 -0.0098038
POLR2J polymerase (RNA) II (DNA directed) polypeptide J, 13.3kDa -0.00972694
NRGN neurogranin (protein kinase C substrate, RC3) -0.00970023
TIMP1 TIMP metallopeptidase inhibitor 1 -0.00954599
GAL galanin/GMAP prepropeptide -0.0094126
EIF5A eukaryotic translation initiation factor 5A -0.00940358
TFF3 trefoil factor 3 (intestinal) -0.00932975
FBN2 fibrillin 2 -0.00922838
ZNHIT1 zinc finger, HIT-type containing 1 -0.00915053
KRAS Kirsten rat sarcoma viral oncogene homolog -0.00910098
TAGLN2 transgelin 2 -0.00908311
DSE dermatan sulfate epimerase -0.00904923
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) -0.00885858
ATP5MF ATP synthase membrane subunit f -0.0088458
STC2 stanniocalcin 2 -0.00883794
RGS13 regulator of G-protein signaling 13 -0.00880924
STK39 serine threonine kinase 39 -0.00870812
POP7 processing of precursor 7, ribonuclease P/MRP subunit (S. cerevisiae) -0.00859808
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha -0.00859458
EMP3 epithelial membrane protein 3 -0.00857477
LOXL1 lysyl oxidase-like 1 -0.00851224
ARPC1A actin related protein 2/3 complex, subunit 1A, 41kDa -0.00845318
SPON2 spondin 2, extracellular matrix protein -0.00843046
STK26 serine/threonine protein kinase 26 -0.00832438
SPINK1 serine peptidase inhibitor, Kazal type 1 -0.00831743
GNB2 guanine nucleotide binding protein (G protein), beta polypeptide 2 -0.00828093
NUDT11 nudix (nucleoside diphosphate linked moiety X)-type motif 11 -0.00827807
MYBPC1 myosin binding protein C, slow type -0.00827741
MAP3K7CL MAP3K7 C-terminal like -0.00804755
SH3BGRL3 SH3 domain binding glutamate-rich protein like 3 -0.00804252
PFKM phosphofructokinase, muscle -0.00804205
RABAC1 Rab acceptor 1 (prenylated) -0.00796417
DCLK1 doublecortin-like kinase 1 -0.00795942
APLP2 amyloid beta (A4) precursor-like protein 2 -0.00795738
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 -0.00794442
GSPT2 G1 to S phase transition 2 -0.00793691
LSP1 lymphocyte-specific protein 1 -0.007933
MBL2 mannose-binding lectin (protein C) 2, soluble -0.00785202
AQP9 aquaporin 9 -0.00781225
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1) -0.00768572
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) -0.00757458
GPX1 glutathione peroxidase 1 -0.0075298
IFI30 interferon, gamma-inducible protein 30 -0.00746803
CLSTN2 calsyntenin 2 -0.0074447
PXDN peroxidasin -0.00743525
HK2 hexokinase 2 -0.00742269
PPP1R1A protein phosphatase 1, regulatory (inhibitor) subunit 1A -0.00742165
ITGBL1 integrin, beta-like 1 (with EGF-like repeat domains) -0.00739936
MTCL1 microtubule crosslinking factor 1 -0.00736681
FUCA1 fucosidase, alpha-L- 1, tissue -0.00734735
BMP2K BMP2 inducible kinase -0.00733808
TCF4 transcription factor 4 -0.00731666
ESR1 estrogen receptor 1 -0.00728455
CCNG2 cyclin G2 -0.00728272
ELK3 ELK3, ETS-domain protein (SRF accessory protein 2) -0.00725553
DEPTOR DEP domain containing MTOR-interacting protein -0.00723958
NOTCH2 notch 2 -0.00722034
PDLIM5 PDZ and LIM domain 5 -0.00720184
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1 -0.00717801
TNNT1 troponin T type 1 (skeletal, slow) -0.00717396
NOTCH2NL notch 2 N-terminal like -0.00717231
SH3BGRL SH3 domain binding glutamate-rich protein like -0.00714177
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide -0.00709862
FAM110B family with sequence similarity 110, member B -0.00709565
EPHA4 EPH receptor A4 -0.00707173
NDUFA3 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa -0.0070573
ARMCX1 armadillo repeat containing, X-linked 1 -0.00705583
PSG5 pregnancy specific beta-1-glycoprotein 5 -0.00702983
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) -0.0070144
RHOD ras homolog family member D -0.00698181
UBA1 ubiquitin-like modifier activating enzyme 1 -0.00691373
WASL Wiskott-Aldrich syndrome-like -0.006872
CAPG capping protein (actin filament), gelsolin-like -0.00685802
TEX10 testis expressed 10 -0.00682954
CLU clusterin -0.00682437
CST3 cystatin C -0.00681785
IGFBP6 insulin-like growth factor binding protein 6 -0.00681145
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase -0.00678761
REXO2 RNA exonuclease 2 -0.00678658
MMP9 matrix metallopeptidase 9 -0.00678625
LRRC31 leucine rich repeat containing 31 -0.00677383
ADGRE1 adhesion G protein-coupled receptor E1 -0.00675404
EREG epiregulin -0.00674816
MYL1 myosin, light chain 1, alkali; skeletal, fast -0.0067438
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase -0.00673228
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -0.00670584
PDGFC platelet derived growth factor C -0.0066867
SH3GLB2 SH3-domain GRB2-like endophilin B2 -0.00668006
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2 -0.00666682
SULT1C2 sulfotransferase family, cytosolic, 1C, member 2 -0.00666189
HOXB2 homeobox B2 -0.00665288
CD84 CD84 molecule -0.00665177
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) -0.00659284
MLF2 myeloid leukemia factor 2 -0.00658654
NANOG Nanog homeobox -0.00657718
MCUB mitochondrial calcium uniporter dominant negative subunit beta -0.00657132
PILRB paired immunoglobin-like type 2 receptor beta -0.00656536
CD37 CD37 molecule -0.00656409
TSPAN5 tetraspanin 5 -0.00655977
ELAPOR1 endosome-lysosome associated apoptosis and autophagy regulator 1 -0.00655401
CXCL13 chemokine (C-X-C motif) ligand 13 -0.00654604
IL1RN interleukin 1 receptor antagonist -0.00653274
MT1E metallothionein 1E -0.00653057
PPM1B protein phosphatase, Mg2+/Mn2+ dependent, 1B -0.00652639
FAM3C family with sequence similarity 3, member C -0.00652461
CCL19 chemokine (C-C motif) ligand 19 -0.00651154
TRIP6 thyroid hormone receptor interactor 6 -0.00651065
CYB5A cytochrome b5 type A (microsomal) -0.006476
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced -0.00645726
RAB38 RAB38, member RAS oncogene family -0.00645571
ARMCX2 armadillo repeat containing, X-linked 2 -0.00644628
AP2M1 adaptor-related protein complex 2, mu 1 subunit -0.006432
WDR7 WD repeat domain 7 -0.00642357
SOD2 superoxide dismutase 2, mitochondrial -0.00639993
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1 -0.0063903
GPNMB glycoprotein (transmembrane) nmb -0.00638837
PDE4DIP phosphodiesterase 4D interacting protein -0.00637616
TLK2 tousled-like kinase 2 -0.00636833
PHLDA2 pleckstrin homology-like domain, family A, member 2 -0.00635898
PRKCZ protein kinase C, zeta -0.00634076
ANXA10 annexin A10 -0.00633917
PKM pyruvate kinase, muscle -0.00631139
AMDHD2 amidohydrolase domain containing 2 -0.00630787
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated) -0.00629071
RMND5B required for meiotic nuclear division 5 homolog B (S. cerevisiae) -0.00628584
MYL2 myosin, light chain 2, regulatory, cardiac, slow -0.006255
BST2 bone marrow stromal cell antigen 2 -0.00624373
GSTP1 glutathione S-transferase pi 1 -0.00623646
MYOZ2 myozenin 2 -0.00622036
PF4 platelet factor 4 -0.00621837
MYOM1 myomesin 1 -0.00619679
RIPOR2 RHO family interacting cell polarization regulator 2 -0.00618376
ARHGAP22 Rho GTPase activating protein 22 -0.00618355
KRT34 keratin 34, type I -0.00617409
CRP C-reactive protein, pentraxin-related -0.00615677
TPD52L2 tumor protein D52-like 2 -0.00609592
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3 -0.00604737
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1 -0.00603715
MRPS12 mitochondrial ribosomal protein S12 -0.00602561
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9 -0.0060222
GBAP1 glucosidase, beta, acid pseudogene 1 -0.00602119
CDC34 cell division cycle 34 -0.00602109
FKBP11 FK506 binding protein 11, 19 kDa -0.00597691
KLHL41 kelch-like family member 41 -0.00597317
ARF5 ADP-ribosylation factor 5 -0.0059617
CD9 CD9 molecule -0.00596051
CKM creatine kinase, muscle -0.00595701
LST1 leukocyte specific transcript 1 -0.0059275
GET3 guided entry of tail-anchored proteins factor 3, ATPase -0.00592322
COPE coatomer protein complex, subunit epsilon -0.00589215
MAGED1 melanoma antigen family D1 -0.0058611
APOB apolipoprotein B -0.00585192
ZNF117 zinc finger protein 117 -0.00584728
PPP2R3A protein phosphatase 2, regulatory subunit B'', alpha -0.00584353
ZCCHC2 zinc finger, CCHC domain containing 2 -0.00579363
TAF6 TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa -0.00576713
NMU neuromedin U -0.00575983
PHACTR2 phosphatase and actin regulator 2 -0.00575833
RP2 retinitis pigmentosa 2 (X-linked recessive) -0.00575805
BAD BCL2-associated agonist of cell death -0.00573655
WDR13 WD repeat domain 13 -0.00573468
IDO1 indoleamine 2,3-dioxygenase 1 -0.00572803
EFHD2 EF-hand domain family, member D2 -0.00569427
MYBPC2 myosin binding protein C, fast type -0.00567779
LSM4 LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae) -0.00565858
PPP1R3C protein phosphatase 1, regulatory subunit 3C -0.00565275
PDAP1 PDGFA associated protein 1 -0.00564822
HHEX hematopoietically expressed homeobox -0.00564662
BET1 Bet1 golgi vesicular membrane trafficking protein -0.00564425
EEF1A2 eukaryotic translation elongation factor 1 alpha 2 -0.00562546
RNASE1 ribonuclease, RNase A family, 1 (pancreatic) -0.00561236
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2 -0.00561086
CAPZA2 capping protein (actin filament) muscle Z-line, alpha 2 -0.00560786
PGRMC2 progesterone receptor membrane component 2 -0.00560182
BLNK B-cell linker -0.00560117
MPC2 mitochondrial pyruvate carrier 2 -0.00559114
ORC5 origin recognition complex, subunit 5 -0.00559081
SIKE1 suppressor of IKBKE 1 -0.00555748
GLA galactosidase, alpha -0.00555693
ADGRE2 adhesion G protein-coupled receptor E2 -0.00552567
SCGB2A1 secretoglobin, family 2A, member 1 -0.0055214
MYT1L myelin transcription factor 1-like -0.00550409
CIDEA cell death-inducing DFFA-like effector a -0.00550363
PDZK1 PDZ domain containing 1 -0.00548936
ZNF43 zinc finger protein 43 -0.00547634
CITED1 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1 -0.00547501
TNNT3 troponin T type 3 (skeletal, fast) -0.00547499
SIGLEC15 sialic acid binding Ig-like lectin 15 -0.00545773
BTK Bruton agammaglobulinemia tyrosine kinase -0.00545261
TIMM13 translocase of inner mitochondrial membrane 13 homolog (yeast) -0.00545218
UGT2B15 UDP glucuronosyltransferase 2 family, polypeptide B15 -0.00544748
GBE1 glucan (1,4-alpha-), branching enzyme 1 -0.00542273
TLE4 transducin-like enhancer of split 4 -0.00542128
AMPH amphiphysin -0.00541806
CD52 CD52 molecule -0.00541408
SCGB1D2 secretoglobin, family 1D, member 2 -0.00540383
RAB3B RAB3B, member RAS oncogene family -0.00540253
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon -0.00539542
GLRX2 glutaredoxin 2 -0.0053876
LAT2 linker for activation of T cells family, member 2 -0.00537834
ATP6V1F ATPase, H+ transporting, lysosomal 14kDa, V1 subunit F -0.00534838
TRRAP transformation/transcription domain-associated protein -0.00534768
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 -0.00532966
QSOX1 quiescin Q6 sulfhydryl oxidase 1 -0.00531434
ZNF91 zinc finger protein 91 -0.0052984
CAMK2B calcium/calmodulin-dependent protein kinase II beta -0.0052896
CERS4 ceramide synthase 4 -0.00528908
PLIN1 perilipin 1 -0.00527783
CCN3 cellular communication network factor 3 -0.00527316
STXBP2 syntaxin binding protein 2 -0.00526284
FZD2 frizzled class receptor 2 -0.00525981
RTN2 reticulon 2 -0.00525625
CUX1 cut-like homeobox 1 -0.00523499
SOX11 SRY (sex determining region Y)-box 11 -0.00523151
FXYD6 FXYD domain containing ion transport regulator 6 -0.00522596
TPM3 tropomyosin 3 -0.00522481
NAMPT nicotinamide phosphoribosyltransferase -0.00522177
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 -0.00521054
NFE2 nuclear factor, erythroid 2 -0.00520827
SLC44A4 solute carrier family 44, member 4 -0.0052072
EHBP1L1 EH domain binding protein 1-like 1 -0.00520043
RUFY3 RUN and FYVE domain containing 3 -0.00519641
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 -0.00517908
SHFM1 split hand/foot malformation (ectrodactyly) type 1 -0.00516544
CHPF2 chondroitin polymerizing factor 2 -0.00516202
WISP2 WNT1 inducible signaling pathway protein 2 -0.00515573
ARHGAP44 Rho GTPase activating protein 44 -0.00515448
PERP PERP, TP53 apoptosis effector -0.00515044
ANAPC2 anaphase promoting complex subunit 2 -0.00514229
TCL1A T-cell leukemia/lymphoma 1A -0.00514165
ARG1 arginase 1 -0.00513998
SLN sarcolipin -0.00512358
ANKRD28 ankyrin repeat domain 28 -0.0051194
CROCCP2 ciliary rootlet coiled-coil, rootletin pseudogene 2 -0.00511374
ADIPOQ adiponectin, C1Q and collagen domain containing -0.0051119