CAY-10397-7071 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

200 genes differentially expressed following the CAY-10397-7071 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAGAB alpha- and gamma-adaptin binding protein
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
AKAP17A A kinase (PRKA) anchor protein 17A
ANOS1 anosmin 1
AP1S2 adaptor-related protein complex 1, sigma 2 subunit
ARMC6 armadillo repeat containing 6
ATF7IP activating transcription factor 7 interacting protein
ATP11A ATPase, class VI, type 11A
BHLHE40 basic helix-loop-helix family, member e40
BIN1 bridging integrator 1
CACTIN cactin, spliceosome C complex subunit
CCPG1 cell cycle progression 1
CCRL2 chemokine (C-C motif) receptor-like 2
CDK13 cyclin-dependent kinase 13
CES2 carboxylesterase 2
DCAF11 DDB1 and CUL4 associated factor 11
DDR1-AS1 DDR1 antisense RNA 1 (head to head)
DDX28 DEAD (Asp-Glu-Ala-Asp) box polypeptide 28
EIF4E2 eukaryotic translation initiation factor 4E family member 2
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1
EPHB4 EPH receptor B4
ERAP1 endoplasmic reticulum aminopeptidase 1
FBRS fibrosin
FLJ11292
FOXG1 forkhead box G1
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
GAREM GRB2 associated, regulator of MAPK1
GLTSCR1 glioma tumor suppressor candidate region gene 1
H6PD hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
HDAC7 histone deacetylase 7
HGH1 HGH1 homolog (S. cerevisiae)
HHEX hematopoietically expressed homeobox
HLX H2.0-like homeobox
IL15RA interleukin 15 receptor, alpha
JUNB jun B proto-oncogene
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KCNJ8 potassium channel, inwardly rectifying subfamily J, member 8
KDM4B lysine (K)-specific demethylase 4B
KIAA1644 KIAA1644
KIF5C kinesin family member 5C
KLHL3 kelch-like family member 3
KRAS Kirsten rat sarcoma viral oncogene homolog
LIMK2 LIM domain kinase 2
MAPK1IP1L mitogen-activated protein kinase 1 interacting protein 1-like
MED1 mediator complex subunit 1
MED22 mediator complex subunit 22
MGC12488
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
MN1 meningioma (disrupted in balanced translocation) 1
MRPL52 mitochondrial ribosomal protein L52
MTERF4 mitochondrial transcription termination factor 4
MUC1 mucin 1, cell surface associated
MXD4 MAX dimerization protein 4
NF2 neurofibromin 2 (merlin)
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
NXPH4 neurexophilin 4
P3H4 prolyl 3-hydroxylase family member 4 (non-enzymatic)
PARD6A par-6 family cell polarity regulator alpha
PC pyruvate carboxylase
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PPT2 palmitoyl-protein thioesterase 2
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2
RDH11 retinol dehydrogenase 11 (all-trans/9-cis/11-cis)
RNF123 ring finger protein 123
RNF19B ring finger protein 19B
SCAMP5 secretory carrier membrane protein 5
SETD4 SET domain containing 4
SFTPB surfactant protein B
SIRT6 sirtuin 6
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC39A9 solute carrier family 39, member 9
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
SNRK SNF related kinase
SORBS3 sorbin and SH3 domain containing 3
SPTAN1 spectrin, alpha, non-erythrocytic 1
SRCAP Snf2-related CREBBP activator protein
STX7 syntaxin 7
SULT1A2 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
SYT17 synaptotagmin XVII
TAF9B TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa
TAGLN3 transgelin 3
TCP11L1 t-complex 11, testis-specific-like 1
TEAD3 TEA domain family member 3
TMEM184C transmembrane protein 184C
TOB2 transducer of ERBB2, 2
TRIM45 tripartite motif containing 45
TTC38 tetratricopeptide repeat domain 38
TXNRD3 thioredoxin reductase 3
UBQLN4 ubiquilin 4
VPRBP Vpr (HIV-1) binding protein
WDFY3 WD repeat and FYVE domain containing 3
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial
ZBTB1 zinc finger and BTB domain containing 1
ZMAT5 zinc finger, matrin-type 5
ZMIZ2 zinc finger, MIZ-type containing 2
ZNF230 zinc finger protein 230
ZNF444 zinc finger protein 444
ZNF492 zinc finger protein 492
ZNF667 zinc finger protein 667

decreased expression

Symbol Name
ADAM15 ADAM metallopeptidase domain 15
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent
AGBL5 ATP/GTP binding protein-like 5
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
ANG angiogenin, ribonuclease, RNase A family, 5
ANKFY1 ankyrin repeat and FYVE domain containing 1
AP4M1 adaptor-related protein complex 4, mu 1 subunit
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
ATG2B autophagy related 2B
AXIN1 axin 1
BCL2L2 BCL2-like 2
BDH1 3-hydroxybutyrate dehydrogenase, type 1
C7ORF43 chromosome 7 open reading frame 43
CASZ1 castor zinc finger 1
CCDC6 coiled-coil domain containing 6
CCNO cyclin O
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CHML choroideremia-like (Rab escort protein 2)
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1
DARS2 aspartyl-tRNA synthetase 2, mitochondrial
DTX2 deltex 2, E3 ubiquitin ligase
EFNA3 ephrin-A3
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
ERCC5 excision repair cross-complementation group 5
ERF Ets2 repressor factor
ETV6 ets variant 6
FAM63A family with sequence similarity 63, member A
FBXL2 F-box and leucine-rich repeat protein 2
FLVCR2 feline leukemia virus subgroup C cellular receptor family, member 2
FSTL3 follistatin-like 3 (secreted glycoprotein)
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2
GDAP1 ganglioside induced differentiation associated protein 1
GPX2 glutathione peroxidase 2
GRAMD1C GRAM domain containing 1C
HOXA4 homeobox A4
HSD17B8 hydroxysteroid (17-beta) dehydrogenase 8
IKZF5 IKAROS family zinc finger 5 (Pegasus)
IL11RA interleukin 11 receptor, alpha
INF2 inverted formin, FH2 and WH2 domain containing
ITK IL2-inducible T-cell kinase
KDM8 lysine (K)-specific demethylase 8
KLHL12 kelch-like family member 12
LGMN legumain
LOC100127972 uncharacterized LOC100127972
LOC390998 ribosomal protein L10 pseudogene
MCMBP minichromosome maintenance complex binding protein
MED9 mediator complex subunit 9
METTL8 methyltransferase like 8
MFSD6 major facilitator superfamily domain containing 6
MLYCD malonyl-CoA decarboxylase
MOXD1 monooxygenase, DBH-like 1
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
NID2 nidogen 2 (osteonidogen)
NUS1P3 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) pseudogene 3
OPLAH 5-oxoprolinase (ATP-hydrolysing)
P2RX4 purinergic receptor P2X, ligand gated ion channel, 4
PCBP4 poly(rC) binding protein 4
PHLDA3 pleckstrin homology-like domain, family A, member 3
PLD3 phospholipase D family, member 3
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
POLR2J2 polymerase (RNA) II (DNA directed) polypeptide J2
PPP1R14D protein phosphatase 1, regulatory (inhibitor) subunit 14D
PPP1R9A protein phosphatase 1, regulatory subunit 9A
PRR4 proline rich 4 (lacrimal)
PRR7 proline rich 7 (synaptic)
PSENEN presenilin enhancer gamma secretase subunit
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa
RABGGTA Rab geranylgeranyltransferase, alpha subunit
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RCOR3 REST corepressor 3
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
SARS2 seryl-tRNA synthetase 2, mitochondrial
SDC3 syndecan 3
SEC61A2 Sec61 alpha 2 subunit (S. cerevisiae)
SENP2 SUMO1/sentrin/SMT3 specific peptidase 2
SERTAD3 SERTA domain containing 3
SGK2 serum/glucocorticoid regulated kinase 2
SLC25A40 solute carrier family 25, member 40
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
STAC SH3 and cysteine rich domain
TCTN2 tectonic family member 2
THOC6 THO complex 6
TMC7 transmembrane channel-like 7
TMEM159 transmembrane protein 159
TMEM183A transmembrane protein 183A
TMEM209 transmembrane protein 209
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TTC12 tetratricopeptide repeat domain 12
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
UNC93B1 unc-93 homolog B1 (C. elegans)
USP19 ubiquitin specific peptidase 19
WBSCR16 Williams-Beuren syndrome chromosome region 16
ZBTB38 zinc finger and BTB domain containing 38
ZNF124 zinc finger protein 124
ZNF197 zinc finger protein 197
ZNF32 zinc finger protein 32
ZNF668 zinc finger protein 668