| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | Cbl proto-oncogene, E3 ubiquitin protein ligase|This gene is a proto-oncogene that encodes a RING finger E3 ubiquitin ligase. The encoded protein is one of the enzymes required for targeting substrates for degradation by the proteasome. This protein mediates the transfer of ubiquitin from ubiquitin conjugating enzymes (E2) to specific substrates. This protein also contains an N-terminal phosphotyrosine binding domain that allows it to interact with numerous tyrosine-phosphorylated substrates and target them for proteasome degradation. As such it functions as a negative regulator of many signal transduction pathways. This gene has been found to be mutated or translocated in many cancers including acute myeloid leukaemia. Mutations in this gene are also the cause of Noonan syndrome-like disorder. [provided by RefSeq, Mar 2012] (NCBI Entrez Gene Database, 867) |
| External Link | https://ncbi.nlm.nih.gov/gene/867 |
| Similar Terms | |
| Downloads & Tools |
499 genes differentially expressed following the CBL gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| BMP4 | bone morphogenetic protein 4 | 0.0181592 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.0145862 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0136856 |
| TXLNA | taxilin alpha | 0.0126495 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.0123093 |
| H1-0 | H1.0 linker histone | 0.0117601 |
| KRT7 | keratin 7, type II | 0.0116153 |
| MMP7 | matrix metallopeptidase 7 | 0.0111088 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.010972 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | 0.0106872 |
| G0S2 | G0/G1 switch 2 | 0.0106533 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | 0.010344 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | 0.0103157 |
| PROM1 | prominin 1 | 0.0101214 |
| BAD | BCL2-associated agonist of cell death | 0.00993264 |
| SLC38A1 | solute carrier family 38, member 1 | 0.00986765 |
| DUSP5 | dual specificity phosphatase 5 | 0.00967116 |
| PLK2 | polo-like kinase 2 | 0.00965859 |
| KAZN | kazrin, periplakin interacting protein | 0.00962003 |
| PDLIM4 | PDZ and LIM domain 4 | 0.00961153 |
| RRAGA | Ras-related GTP binding A | 0.00940877 |
| CLGN | calmegin | 0.00917219 |
| KRT19 | keratin 19, type I | 0.00907999 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.00904579 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.00903363 |
| TGFA | transforming growth factor, alpha | 0.00894527 |
| PHACTR2 | phosphatase and actin regulator 2 | 0.00885001 |
| TOB1 | transducer of ERBB2, 1 | 0.00881963 |
| EFHD2 | EF-hand domain family, member D2 | 0.00867714 |
| CST3 | cystatin C | 0.00867431 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | 0.00861354 |
| TBC1D9 | TBC1 domain family, member 9 (with GRAM domain) | 0.00855335 |
| PERP | PERP, TP53 apoptosis effector | 0.0085438 |
| SQLE | squalene epoxidase | 0.00844634 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.00836629 |
| GNA11 | guanine nucleotide binding protein (G protein), alpha 11 (Gq class) | 0.00828016 |
| RNPS1 | RNA binding protein S1, serine-rich domain | 0.00820679 |
| AMDHD2 | amidohydrolase domain containing 2 | 0.00814779 |
| STC2 | stanniocalcin 2 | 0.00805616 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0080287 |
| PEG3 | paternally expressed 3 | 0.0079998 |
| MGLL | monoglyceride lipase | 0.00783468 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 0.00780205 |
| MYO6 | myosin VI | 0.00776208 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.00769199 |
| AACS | acetoacetyl-CoA synthetase | 0.00754516 |
| CCNG2 | cyclin G2 | 0.0075304 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.00742393 |
| HSPA1A | heat shock 70kDa protein 1A | 0.0074131 |
| SLC3A2 | solute carrier family 3 (amino acid transporter heavy chain), member 2 | 0.00725103 |
| DHCR24 | 24-dehydrocholesterol reductase | 0.00723985 |
| LTBP2 | latent transforming growth factor beta binding protein 2 | 0.00717304 |
| AKR1C3 | aldo-keto reductase family 1, member C3 | 0.00715107 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 0.00710914 |
| NAV3 | neuron navigator 3 | 0.00709155 |
| FADS1 | fatty acid desaturase 1 | 0.00708305 |
| QPCT | glutaminyl-peptide cyclotransferase | 0.00708213 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) | 0.00705501 |
| SYNM | synemin, intermediate filament protein | 0.00703012 |
| TSC22D2 | TSC22 domain family, member 2 | 0.00698293 |
| CBX6 | chromobox homolog 6 | 0.00693534 |
| ELK3 | ELK3, ETS-domain protein (SRF accessory protein 2) | 0.00690444 |
| SMARCA2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 | 0.00688047 |
| NIBAN1 | niban apoptosis regulator 1 | 0.00687973 |
| UBE2S | ubiquitin-conjugating enzyme E2S | 0.00687202 |
| ZNF91 | zinc finger protein 91 | 0.00683497 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | 0.00681147 |
| PLAAT3 | phospholipase A and acyltransferase 3 | 0.00680063 |
| EIF5A | eukaryotic translation initiation factor 5A | 0.00678467 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.00677707 |
| GSTM3 | glutathione S-transferase mu 3 (brain) | 0.00676337 |
| TSPYL5 | TSPY-like 5 | 0.00675641 |
| SH3GLB2 | SH3-domain GRB2-like endophilin B2 | 0.00674272 |
| CYBA | cytochrome b-245, alpha polypeptide | 0.0067226 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | 0.00670429 |
| GOLGA8A | golgin A8 family, member A | 0.00670291 |
| HIST1H2BK | histone cluster 1, H2bk | 0.0066858 |
| KMT5B | lysine methyltransferase 5B | 0.00667942 |
| CDR2L | cerebellar degeneration-related protein 2-like | 0.00664321 |
| FST | follistatin | 0.00664304 |
| H1-10 | H1.10 linker histone | 0.00658554 |
| KCTD5 | potassium channel tetramerization domain containing 5 | 0.00657008 |
| MYBPC1 | myosin binding protein C, slow type | 0.00656192 |
| PDGFC | platelet derived growth factor C | 0.00652384 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | 0.00643967 |
| TEX10 | testis expressed 10 | 0.00641103 |
| CTSH | cathepsin H | 0.0063891 |
| LMO2 | LIM domain only 2 (rhombotin-like 1) | 0.00636839 |
| ANXA3 | annexin A3 | 0.00636689 |
| CEBPB | CCAAT/enhancer binding protein (C/EBP), beta | 0.00633059 |
| ABHD3 | abhydrolase domain containing 3 | 0.006248 |
| CSRP3 | cysteine and glycine-rich protein 3 (cardiac LIM protein) | 0.0062442 |
| PPIF | peptidylprolyl isomerase F | 0.00623216 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.00622807 |
| S100P | S100 calcium binding protein P | 0.00621643 |
| UPF3A | UPF3 regulator of nonsense transcripts homolog A (yeast) | 0.0061487 |
| PRSS3 | protease, serine, 3 | 0.00612871 |
| EMP3 | epithelial membrane protein 3 | 0.00611953 |
| JMJD1C | jumonji domain containing 1C | 0.00610783 |
| BIK | BCL2-interacting killer (apoptosis-inducing) | 0.00609194 |
| RRAGD | Ras-related GTP binding D | 0.00606825 |
| CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) | 0.0060483 |
| SULT1C2 | sulfotransferase family, cytosolic, 1C, member 2 | 0.00604662 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.00600864 |
| NMU | neuromedin U | 0.0059958 |
| CEBPG | CCAAT/enhancer binding protein (C/EBP), gamma | 0.00593398 |
| RNF6 | ring finger protein (C3H2C3 type) 6 | 0.00592815 |
| ANXA5 | annexin A5 | 0.00592279 |
| ALDH2 | aldehyde dehydrogenase 2 family (mitochondrial) | 0.00587459 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.00586211 |
| ARID4A | AT rich interactive domain 4A (RBP1-like) | 0.00584663 |
| ANPEP | alanyl (membrane) aminopeptidase | 0.00582992 |
| ABHD2 | abhydrolase domain containing 2 | 0.00582928 |
| ACSL1 | acyl-CoA synthetase long-chain family member 1 | 0.00580486 |
| ARGLU1 | arginine and glutamate rich 1 | 0.00579558 |
| POU2AF1 | POU class 2 associating factor 1 | 0.00577913 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) | 0.00577907 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | 0.00577726 |
| MT1E | metallothionein 1E | 0.00577178 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | 0.00575311 |
| CPB1 | carboxypeptidase B1 (tissue) | 0.0057357 |
| SLC39A4 | solute carrier family 39 (zinc transporter), member 4 | 0.00573501 |
| LSS | lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) | 0.00573213 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | 0.00570423 |
| CXCL6 | chemokine (C-X-C motif) ligand 6 | 0.00569277 |
| RAB7A | RAB7A, member RAS oncogene family | 0.00569131 |
| MACROD1 | MACRO domain containing 1 | 0.00568906 |
| DHCR7 | 7-dehydrocholesterol reductase | 0.00568489 |
| ZBTB18 | zinc finger and BTB domain containing 18 | 0.00568413 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | 0.00566619 |
| SGCE | sarcoglycan, epsilon | 0.00565963 |
| TXNRD1 | thioredoxin reductase 1 | 0.00565944 |
| IQCG | IQ motif containing G | 0.00565904 |
| TSPAN8 | tetraspanin 8 | 0.00565868 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.00565196 |
| CHPT1 | choline phosphotransferase 1 | 0.00564951 |
| INPP5A | inositol polyphosphate-5-phosphatase, 40kDa | 0.00563288 |
| PLEC | plectin | 0.00563121 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.00557494 |
| PSCA | prostate stem cell antigen | 0.00557052 |
| CMTM6 | CKLF-like MARVEL transmembrane domain containing 6 | 0.00554557 |
| GRAMD1B | GRAM domain containing 1B | 0.00554177 |
| EIF5B | eukaryotic translation initiation factor 5B | 0.00553911 |
| PCDH9 | protocadherin 9 | 0.00551748 |
| TNFAIP8 | tumor necrosis factor, alpha-induced protein 8 | 0.00551174 |
| BRD2 | bromodomain containing 2 | 0.00550878 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) | 0.00549858 |
| SIM2 | single-minded family bHLH transcription factor 2 | 0.00549432 |
| NOTCH2 | notch 2 | 0.0054808 |
| TSPAN5 | tetraspanin 5 | 0.00546872 |
| IGFBP1 | insulin-like growth factor binding protein 1 | 0.00546406 |
| PDE1A | phosphodiesterase 1A, calmodulin-dependent | 0.00546113 |
| SEPHS2 | selenophosphate synthetase 2 | 0.00545544 |
| KRAS | Kirsten rat sarcoma viral oncogene homolog | 0.00545477 |
| PCP4 | Purkinje cell protein 4 | 0.00545239 |
| PEG10 | paternally expressed 10 | 0.00545072 |
| MAGEB2 | melanoma antigen family B2 | 0.0054368 |
| KIF5B | kinesin family member 5B | 0.00542219 |
| BICC1 | BicC family RNA binding protein 1 | 0.00540359 |
| AHNAK | AHNAK nucleoprotein | 0.00540065 |
| EFNB2 | ephrin-B2 | 0.00539399 |
| KCTD12 | potassium channel tetramerization domain containing 12 | 0.0053857 |
| PITX1 | paired-like homeodomain 1 | 0.00538303 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.00538266 |
| CLCN4 | chloride channel, voltage-sensitive 4 | 0.00538204 |
| CTSE | cathepsin E | 0.00535899 |
| SGPL1 | sphingosine-1-phosphate lyase 1 | 0.00535407 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.00534192 |
| REG1A | regenerating islet-derived 1 alpha | 0.00534115 |
| GATM | glycine amidinotransferase (L-arginine:glycine amidinotransferase) | 0.00531717 |
| RABEP2 | rabaptin, RAB GTPase binding effector protein 2 | 0.00531568 |
| PXDC1 | PX domain containing 1 | 0.00530637 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | 0.00529879 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 0.00529302 |
| PNKP | polynucleotide kinase 3'-phosphatase | 0.00527457 |
| LYZ | lysozyme | 0.00526673 |
| MCM2 | minichromosome maintenance complex component 2 | 0.00526658 |
| VGLL4 | vestigial-like family member 4 | 0.00524928 |
| HLA-B | major histocompatibility complex, class I, B | 0.00524083 |
| MSMO1 | methylsterol monooxygenase 1 | 0.00522284 |
| MGAT4B | mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B | 0.00521164 |
| HIP1R | huntingtin interacting protein 1 related | 0.00519817 |
| SFXN3 | sideroflexin 3 | 0.00519238 |
| MT2A | metallothionein 2A | 0.00519142 |
| JUNB | jun B proto-oncogene | 0.00519108 |
| ZCCHC8 | zinc finger, CCHC domain containing 8 | 0.00518435 |
| HMOX1 | heme oxygenase 1 | 0.00514787 |
| LCN2 | lipocalin 2 | 0.0051373 |
| RHOD | ras homolog family member D | 0.0051297 |
| ACAA1 | acetyl-CoA acyltransferase 1 | 0.00511286 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) | 0.00509143 |
| ANKRD10 | ankyrin repeat domain 10 | 0.00508434 |
| CX3CR1 | chemokine (C-X3-C motif) receptor 1 | 0.00505676 |
| RUNX1 | runt-related transcription factor 1 | 0.00503705 |
| GLS | glutaminase | 0.00503358 |
| OAT | ornithine aminotransferase | 0.00503265 |
| CCNE1 | cyclin E1 | 0.00503248 |
| PLIN2 | perilipin 2 | 0.00502839 |
| SKIV2L | superkiller viralicidic activity 2-like (S. cerevisiae) | 0.00502695 |
| CHKA | choline kinase alpha | 0.00501851 |
| MED13 | mediator complex subunit 13 | 0.00501079 |
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide | 0.00501003 |
| BTF3P11 | basic transcription factor 3 pseudogene 11 | 0.00498915 |
| DNAJC12 | DnaJ (Hsp40) homolog, subfamily C, member 12 | 0.00497819 |
| KANK1 | KN motif and ankyrin repeat domains 1 | 0.00497651 |
| CYP51A1 | cytochrome P450, family 51, subfamily A, polypeptide 1 | 0.00497564 |
| PGC | progastricsin (pepsinogen C) | 0.00497338 |
| ABAT | 4-aminobutyrate aminotransferase | 0.00494948 |
| LYN | LYN proto-oncogene, Src family tyrosine kinase | 0.00494865 |
| CLEC11A | C-type lectin domain family 11, member A | 0.0049447 |
| RAMP1 | receptor (G protein-coupled) activity modifying protein 1 | 0.0049442 |
| GALNT3 | polypeptide N-acetylgalactosaminyltransferase 3 | 0.00493891 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | 0.0049151 |
| TSPO | translocator protein (18kDa) | 0.00490613 |
| TBC1D9B | TBC1 domain family, member 9B (with GRAM domain) | 0.00490598 |
| MSLN | mesothelin | 0.00490452 |
| PNMA1 | paraneoplastic Ma antigen 1 | 0.00490105 |
| CLDN10 | claudin 10 | 0.00488498 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.00488097 |
| EPHA2 | EPH receptor A2 | 0.00487332 |
| DACT1 | dishevelled-binding antagonist of beta-catenin 1 | 0.00486098 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.00485442 |
| CCDC92 | coiled-coil domain containing 92 | 0.0048501 |
| C9ORF16 | chromosome 9 open reading frame 16 | 0.00484799 |
| WDTC1 | WD and tetratricopeptide repeats 1 | 0.00483928 |
| MEIS1 | Meis homeobox 1 | 0.00483727 |
| FLNA | filamin A, alpha | 0.00483205 |
| POR | P450 (cytochrome) oxidoreductase | 0.00482508 |
| DACH1 | dachshund family transcription factor 1 | 0.00482327 |
| PTER | phosphotriesterase related | 0.00482118 |
| NPY | neuropeptide Y | 0.00482079 |
| CYTH1 | cytohesin 1 | 0.00481749 |
| MAZ | MYC-associated zinc finger protein (purine-binding transcription factor) | 0.00481731 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 | 0.00481424 |
| FTL | ferritin, light polypeptide | 0.00481188 |
| NAA40 | N(alpha)-acetyltransferase 40, NatD catalytic subunit | 0.00480308 |
| ACTN4 | actinin, alpha 4 | 0.00480162 |
| SLC7A8 | solute carrier family 7 (amino acid transporter light chain, L system), member 8 | 0.00479852 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.00478685 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.00478187 |
| TWF2 | twinfilin actin binding protein 2 | 0.00477679 |
| GNAS | GNAS complex locus | 0.00477382 |
| PPP4C | protein phosphatase 4, catalytic subunit | 0.0047735 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | 0.00477262 |
| NDE1 | nudE neurodevelopment protein 1 | 0.00477212 |
| IL6 | interleukin 6 | 0.00476524 |
| CEP350 | centrosomal protein 350kDa | 0.00476439 |
| FAM117A | family with sequence similarity 117, member A | 0.00476323 |
| KLK11 | kallikrein-related peptidase 11 | 0.00476233 |
| CKM | creatine kinase, muscle | 0.00476187 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 | -0.0114293 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.011133 |
| FBXO11 | F-box protein 11 | -0.0108301 |
| XPO7 | exportin 7 | -0.00978491 |
| GZMA | granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) | -0.00958216 |
| NVL | nuclear VCP-like | -0.00920607 |
| NELL2 | NEL-like 2 (chicken) | -0.00899298 |
| CYTIP | cytohesin 1 interacting protein | -0.00891146 |
| GZMK | granzyme K (granzyme 3; tryptase II) | -0.00883883 |
| CCL5 | chemokine (C-C motif) ligand 5 | -0.00870578 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.00866628 |
| CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 | -0.00859756 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) | -0.00859501 |
| CST7 | cystatin F (leukocystatin) | -0.00850888 |
| NEBL | nebulette | -0.0083957 |
| SELENBP1 | selenium binding protein 1 | -0.00833793 |
| IL2RG | interleukin 2 receptor, gamma | -0.00830052 |
| PTPRZ1 | protein tyrosine phosphatase, receptor-type, Z polypeptide 1 | -0.00829943 |
| CXCL10 | chemokine (C-X-C motif) ligand 10 | -0.00817293 |
| AUTS2 | autism susceptibility candidate 2 | -0.00798448 |
| NQO2 | NAD(P)H dehydrogenase, quinone 2 | -0.00790468 |
| CD8A | CD8a molecule | -0.00790287 |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) | -0.00790093 |
| LAMP3 | lysosomal-associated membrane protein 3 | -0.00783317 |
| ALDOC | aldolase C, fructose-bisphosphate | -0.00775666 |
| CD96 | CD96 molecule | -0.00770201 |
| FZD5 | frizzled class receptor 5 | -0.00752515 |
| LAPTM4B | lysosomal protein transmembrane 4 beta | -0.00752417 |
| BAMBI | BMP and activin membrane-bound inhibitor | -0.00751594 |
| GPR171 | G protein-coupled receptor 171 | -0.00747903 |
| ANOS1 | anosmin 1 | -0.00743299 |
| CASP1 | caspase 1, apoptosis-related cysteine peptidase | -0.00738773 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.00736824 |
| CD52 | CD52 molecule | -0.00736182 |
| CCL4 | chemokine (C-C motif) ligand 4 | -0.00732941 |
| ID4 | inhibitor of DNA binding 4, dominant negative helix-loop-helix protein | -0.00725454 |
| IVNS1ABP | influenza virus NS1A binding protein | -0.00723755 |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 | -0.00723138 |
| ACOT13 | acyl-CoA thioesterase 13 | -0.00722039 |
| CD93 | CD93 molecule | -0.00720531 |
| SLAMF7 | SLAM family member 7 | -0.00720064 |
| RNF125 | ring finger protein 125, E3 ubiquitin protein ligase | -0.00717811 |
| TMEM230 | transmembrane protein 230 | -0.00713284 |
| L1TD1 | LINE-1 type transposase domain containing 1 | -0.00710681 |
| GSTO1 | glutathione S-transferase omega 1 | -0.00709347 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | -0.00707503 |
| GPM6B | glycoprotein M6B | -0.0070411 |
| FAR2 | fatty acyl CoA reductase 2 | -0.0070194 |
| ABCG2 | ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) | -0.00700773 |
| UGP2 | UDP-glucose pyrophosphorylase 2 | -0.00697902 |
| NKG7 | natural killer cell granule protein 7 | -0.00693959 |
| C1QA | complement component 1, q subcomponent, A chain | -0.00686129 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | -0.00685317 |
| GNLY | granulysin | -0.00683726 |
| SFRP4 | secreted frizzled-related protein 4 | -0.00682849 |
| MMP12 | matrix metallopeptidase 12 | -0.00680985 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 | -0.00679928 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | -0.00677422 |
| GPR65 | G protein-coupled receptor 65 | -0.00671047 |
| C1QB | complement component 1, q subcomponent, B chain | -0.00658036 |
| CHKB | choline kinase beta | -0.00655498 |
| BTG3 | BTG family, member 3 | -0.00654557 |
| LEFTY1 | left-right determination factor 1 | -0.00654048 |
| TUBB2B | tubulin, beta 2B class IIb | -0.00653169 |
| GLUL | glutamate-ammonia ligase | -0.00652122 |
| ERAP1 | endoplasmic reticulum aminopeptidase 1 | -0.00651951 |
| GZMB | granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) | -0.00649503 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.00649139 |
| RGS1 | regulator of G-protein signaling 1 | -0.00648463 |
| DYNLT1 | dynein, light chain, Tctex-type 1 | -0.0064829 |
| RAPGEF5 | Rap guanine nucleotide exchange factor (GEF) 5 | -0.00643801 |
| CLEC2B | C-type lectin domain family 2, member B | -0.00642267 |
| FCN3 | ficolin (collagen/fibrinogen domain containing) 3 | -0.00638575 |
| AKAP8 | A kinase (PRKA) anchor protein 8 | -0.00636874 |
| DAZAP2 | DAZ associated protein 2 | -0.00634161 |
| TAF9B | TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa | -0.0063362 |
| CREM | cAMP responsive element modulator | -0.00632481 |
| CLDND1 | claudin domain containing 1 | -0.00631163 |
| ALOX5AP | arachidonate 5-lipoxygenase-activating protein | -0.00631059 |
| TSPAN13 | tetraspanin 13 | -0.00631005 |
| CACNA2D2 | calcium channel, voltage-dependent, alpha 2/delta subunit 2 | -0.00630473 |
| KRT13 | keratin 13, type I | -0.00629695 |
| CYP2A6 | cytochrome P450, family 2, subfamily A, polypeptide 6 | -0.00628317 |
| FOXO1 | forkhead box O1 | -0.00627549 |
| XCL1 | chemokine (C motif) ligand 1 | -0.00624105 |
| CXCL11 | chemokine (C-X-C motif) ligand 11 | -0.00623992 |
| HOPX | HOP homeobox | -0.00620191 |
| GIMAP4 | GTPase, IMAP family member 4 | -0.00616579 |
| RARRES2 | retinoic acid receptor responder (tazarotene induced) 2 | -0.00615932 |
| LMO3 | LIM domain only 3 (rhombotin-like 2) | -0.00615012 |
| PSMF1 | proteasome (prosome, macropain) inhibitor subunit 1 (PI31) | -0.00613935 |
| IDO1 | indoleamine 2,3-dioxygenase 1 | -0.00611523 |
| LPAR6 | lysophosphatidic acid receptor 6 | -0.00608159 |
| RPP40 | ribonuclease P/MRP 40kDa subunit | -0.00603784 |
| EXOC5 | exocyst complex component 5 | -0.00600167 |
| DIAPH2 | diaphanous-related formin 2 | -0.00597872 |
| ALDH5A1 | aldehyde dehydrogenase 5 family, member A1 | -0.00595428 |
| PLS3 | plastin 3 | -0.0059477 |
| FRZB | frizzled-related protein | -0.00589444 |
| JCHAIN | joining chain of multimeric IgA and IgM | -0.00588234 |
| PLP1 | proteolipid protein 1 | -0.00588204 |
| XIC | X chromosome inactivation center | -0.00587738 |
| ARG1 | arginase 1 | -0.00587295 |
| ZNF204P | zinc finger protein 204, pseudogene | -0.00586833 |
| CNIH4 | cornichon family AMPA receptor auxiliary protein 4 | -0.00586485 |
| KRT1 | keratin 1, type II | -0.00586048 |
| EFEMP1 | EGF containing fibulin-like extracellular matrix protein 1 | -0.00585493 |
| CLNS1A | chloride channel, nucleotide-sensitive, 1A | -0.00584295 |
| RGCC | regulator of cell cycle | -0.00583989 |
| GBP1 | guanylate binding protein 1, interferon-inducible | -0.00581076 |
| S100B | S100 calcium binding protein B | -0.00579922 |
| PON3 | paraoxonase 3 | -0.00579293 |
| CD2 | CD2 molecule | -0.0057768 |
| CA4 | carbonic anhydrase IV | -0.00577385 |
| PSMD4 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 | -0.0057727 |
| DLEU1 | deleted in lymphocytic leukemia 1 (non-protein coding) | -0.00577121 |
| NOX1 | NADPH oxidase 1 | -0.00577108 |
| EMC2 | ER membrane protein complex subunit 2 | -0.00576877 |
| PRDX4 | peroxiredoxin 4 | -0.00576555 |
| AQP1 | aquaporin 1 (Colton blood group) | -0.00575425 |
| CNPY3 | canopy FGF signaling regulator 3 | -0.00574054 |
| COMMD10 | COMM domain containing 10 | -0.00571862 |
| S100A9 | S100 calcium binding protein A9 | -0.00571729 |
| DCTN4 | dynactin 4 (p62) | -0.00571239 |
| CD48 | CD48 molecule | -0.00568357 |
| COL3A1 | collagen, type III, alpha 1 | -0.00568137 |
| PSMD10 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 | -0.00567933 |
| CTSS | cathepsin S | -0.00567777 |
| TEK | TEK tyrosine kinase, endothelial | -0.0056538 |
| SAMSN1 | SAM domain, SH3 domain and nuclear localization signals 1 | -0.00565206 |
| NOTCH3 | notch 3 | -0.00564862 |
| ESD | esterase D | -0.00564546 |
| NUDT21 | nudix (nucleoside diphosphate linked moiety X)-type motif 21 | -0.00563425 |
| CLCA4 | chloride channel accessory 4 | -0.00562458 |
| GYPC | glycophorin C (Gerbich blood group) | -0.00560479 |
| PRR15L | proline rich 15-like | -0.00560165 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.00558322 |
| MME | membrane metallo-endopeptidase | -0.00555956 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase | -0.00555699 |
| CD3D | CD3d molecule, delta (CD3-TCR complex) | -0.00555582 |
| LCP2 | lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) | -0.0055434 |
| BCHE | butyrylcholinesterase | -0.00552285 |
| DIPK1A | divergent protein kinase domain 1A | -0.00551466 |
| RFTN1 | raftlin, lipid raft linker 1 | -0.00550018 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) | -0.00549087 |
| CD69 | CD69 molecule | -0.00548546 |
| ADPRM | ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent | -0.00548131 |
| TDP2 | tyrosyl-DNA phosphodiesterase 2 | -0.00547217 |
| EDN1 | endothelin 1 | -0.0054689 |
| UXT | ubiquitously-expressed, prefoldin-like chaperone | -0.0054671 |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit | -0.0054637 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | -0.00546033 |
| CCR5 | chemokine (C-C motif) receptor 5 (gene/pseudogene) | -0.00545536 |
| REEP5 | receptor accessory protein 5 | -0.00544226 |
| KIFAP3 | kinesin-associated protein 3 | -0.00543717 |
| SIRT5 | sirtuin 5 | -0.0054077 |
| RPA2 | replication protein A2, 32kDa | -0.00539883 |
| SOD3 | superoxide dismutase 3, extracellular | -0.00536178 |
| DAXX | death-domain associated protein | -0.00536092 |
| HBB | hemoglobin, beta | -0.00533786 |
| CRELD2 | cysteine-rich with EGF-like domains 2 | -0.00532392 |
| ITGA4 | integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) | -0.00531953 |
| FBXO28 | F-box protein 28 | -0.0053102 |
| GLO1 | glyoxalase I | -0.00530234 |
| SALL2 | spalt-like transcription factor 2 | -0.00528147 |
| PSMA1 | proteasome (prosome, macropain) subunit, alpha type, 1 | -0.00526426 |
| DOCK10 | dedicator of cytokinesis 10 | -0.00524917 |
| WISP2 | WNT1 inducible signaling pathway protein 2 | -0.00524856 |
| KCTD20 | potassium channel tetramerization domain containing 20 | -0.00524666 |
| ME2 | malic enzyme 2, NAD(+)-dependent, mitochondrial | -0.00524133 |
| PTHLH | parathyroid hormone-like hormone | -0.00523857 |
| FGG | fibrinogen gamma chain | -0.00523427 |
| IL7R | interleukin 7 receptor | -0.0052194 |
| NDUFA4L2 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2 | -0.00521595 |
| APOO | apolipoprotein O | -0.0052072 |
| UFSP2 | UFM1-specific peptidase 2 | -0.0052006 |
| ITM2C | integral membrane protein 2C | -0.00519715 |
| SNX13 | sorting nexin 13 | -0.00519187 |
| CD9 | CD9 molecule | -0.00518399 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) | -0.00517697 |
| MYO1B | myosin IB | -0.0051536 |
| SSR1 | signal sequence receptor, alpha | -0.00515262 |
| PDLIM1 | PDZ and LIM domain 1 | -0.00514967 |
| DENND1B | DENN/MADD domain containing 1B | -0.00514378 |
| DNTT | DNA nucleotidylexotransferase | -0.00514064 |
| GJA1 | gap junction protein, alpha 1, 43kDa | -0.00512635 |
| LTA4H | leukotriene A4 hydrolase | -0.00512248 |
| CXADR | coxsackie virus and adenovirus receptor | -0.00512183 |
| HOXB2 | homeobox B2 | -0.0051196 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.00511707 |
| FUT1 | fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) | -0.0050931 |
| SCGB1A1 | secretoglobin, family 1A, member 1 (uteroglobin) | -0.00507575 |
| CDH5 | cadherin 5, type 2 (vascular endothelium) | -0.00507084 |
| RBM8A | RNA binding motif protein 8A | -0.00506988 |
| MMP13 | matrix metallopeptidase 13 | -0.00506968 |
| EGR2 | early growth response 2 | -0.00506779 |
| VAMP5 | vesicle-associated membrane protein 5 | -0.00505978 |
| ADH5 | alcohol dehydrogenase 5 (class III), chi polypeptide | -0.00505619 |
| APOL2 | apolipoprotein L, 2 | -0.00505437 |
| ITGAE | integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) | -0.00504449 |
| MMP9 | matrix metallopeptidase 9 | -0.00503359 |
| FLOT1 | flotillin 1 | -0.00502643 |
| MTHFD1 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase | -0.00501252 |
| S100A8 | S100 calcium binding protein A8 | -0.00500453 |
| CSF2RB | colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) | -0.00499027 |
| SKP1 | S-phase kinase-associated protein 1 | -0.00498533 |
| LEPROTL1 | leptin receptor overlapping transcript-like 1 | -0.0049752 |
| IL2RB | interleukin 2 receptor, beta | -0.004972 |
| PTH2R | parathyroid hormone 2 receptor | -0.00496802 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | -0.00496765 |
| GIMAP5 | GTPase, IMAP family member 5 | -0.00496183 |
| CLEC2D | C-type lectin domain family 2, member D | -0.00496086 |
| TARP | TCR gamma alternate reading frame protein | -0.00495867 |
| ATG5 | autophagy related 5 | -0.00493589 |
| PRDX6 | peroxiredoxin 6 | -0.00492846 |
| RCBTB2 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 | -0.00492542 |
| MOCS2 | molybdenum cofactor synthesis 2 | -0.00490889 |
| COL1A2 | collagen, type I, alpha 2 | -0.00490509 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.00489614 |
| PRF1 | perforin 1 (pore forming protein) | -0.00489025 |
| HOXA5 | homeobox A5 | -0.00487598 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.00486764 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.00486524 |
| PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 | -0.0048602 |
| CEACAM7 | carcinoembryonic antigen-related cell adhesion molecule 7 | -0.00485838 |
| COPS4 | COP9 signalosome subunit 4 | -0.00484871 |
| RBX1 | ring-box 1, E3 ubiquitin protein ligase | -0.00484663 |
| THBS2 | thrombospondin 2 | -0.00484556 |
| IFITM2 | interferon induced transmembrane protein 2 | -0.00483772 |
| FCGBP | Fc fragment of IgG binding protein | -0.00483294 |
| ABHD17B | abhydrolase domain containing 17B | -0.0048302 |
| MS4A12 | membrane-spanning 4-domains, subfamily A, member 12 | -0.00482122 |
| RIPK1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 | -0.00482053 |
| SLC2A5 | solute carrier family 2 (facilitated glucose/fructose transporter), member 5 | -0.0048142 |
| NETO2 | neuropilin (NRP) and tolloid (TLL)-like 2 | -0.00480993 |
| PEX2 | peroxisomal biogenesis factor 2 | -0.0048012 |
| BNC2 | basonuclin 2 | -0.00479308 |
| CYP2B6 | cytochrome P450, family 2, subfamily B, polypeptide 6 | -0.00479285 |
| HSD17B6 | hydroxysteroid (17-beta) dehydrogenase 6 | -0.00478993 |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 | -0.00478935 |
| RALB | v-ral simian leukemia viral oncogene homolog B | -0.00478024 |
| AP3S1 | adaptor-related protein complex 3, sigma 1 subunit | -0.00477368 |
| EDNRB | endothelin receptor type B | -0.00475453 |
| TIE1 | tyrosine kinase with immunoglobulin-like and EGF-like domains 1 | -0.00475407 |
| TERF1 | telomeric repeat binding factor (NIMA-interacting) 1 | -0.00475386 |
| SCGB2A1 | secretoglobin, family 2A, member 1 | -0.00474158 |
| C4BPA | complement component 4 binding protein, alpha | -0.00473709 |
| DPYSL3 | dihydropyrimidinase-like 3 | -0.00472561 |
| ADH1B | alcohol dehydrogenase 1B (class I), beta polypeptide | -0.00471961 |
