CBLN1 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description cerebellin 1 precursor|This gene encodes a cerebellum-specific precursor protein, precerebellin, with similarity to the globular (non-collagen-like) domain of complement component C1qB. Precerebellin is processed to give rise to several derivatives, including the hexadecapeptide, cerebellin, which is highly enriched in postsynaptic structures of Purkinje cells. Cerebellin has also been found in human and rat adrenals, where it has been shown to enhance the secretory activity of this gland. [provided by RefSeq, Aug 2008] (NCBI Entrez Gene Database, 869)
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Genes

329 genes differentially expressed following the CBLN1 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
MAG myelin associated glycoprotein 3.44515
HLX H2.0-like homeobox 3.44515
FOLR1 folate receptor 1 (adult) 3.44515
PLEKHG7 pleckstrin homology domain containing, family G (with RhoGef domain) member 7 3.44515
FGD2 FYVE, RhoGEF and PH domain containing 2 3.44515
CELA3A chymotrypsin-like elastase family, member 3A 3.44515
TMEM151A transmembrane protein 151A 3.44515
CASP4 caspase 4, apoptosis-related cysteine peptidase 3.44515
OR10A3 olfactory receptor, family 10, subfamily A, member 3 3.44515
TMPRSS11F transmembrane protease, serine 11F 3.44515
TMEM212 transmembrane protein 212 3.44515
XPNPEP2 X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound 3.44515
C1ORF87 chromosome 1 open reading frame 87 3.44515
PTPRH protein tyrosine phosphatase, receptor type, H 3.44515
PRB4 proline-rich protein BstNI subfamily 4 3.44515
PCDHA3 protocadherin alpha 3 3.44515
HDC histidine decarboxylase 3.44515
TMEM229A transmembrane protein 229A 3.44515
PRLHR prolactin releasing hormone receptor 3.44515
TPBGL trophoblast glycoprotein-like 3.44515
OSR2 odd-skipped related transciption factor 2 3.44515
SH2D6 SH2 domain containing 6 3.44515
FRMD1 FERM domain containing 1 3.44515
C1ORF141 chromosome 1 open reading frame 141 3.44515
UBA7 ubiquitin-like modifier activating enzyme 7 3.44515
LRRC63 leucine rich repeat containing 63 3.44515
TREML1 triggering receptor expressed on myeloid cells-like 1 3.44515
TSHZ1 teashirt zinc finger homeobox 1 3.44515
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 3.44515
PODNL1 podocan-like 1 3.44515
CHRNB3 cholinergic receptor, nicotinic, beta 3 (neuronal) 3.44515
OR13C3 olfactory receptor, family 13, subfamily C, member 3 3.44515
SLC2A2 solute carrier family 2 (facilitated glucose transporter), member 2 3.44515
CXCL2 chemokine (C-X-C motif) ligand 2 3.44515
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) 3.44515
SIGLEC7 sialic acid binding Ig-like lectin 7 3.44515
OLFM4 olfactomedin 4 3.44515
SSTR5 somatostatin receptor 5 3.44515
CIITA class II, major histocompatibility complex, transactivator 3.44515
GYPB glycophorin B (MNS blood group) 3.44515
MYOM2 myomesin 2 3.44515
C16ORF82 chromosome 16 open reading frame 82 3.44515
HES2 hes family bHLH transcription factor 2 3.44515
DRC5 dynein regulatory complex subunit 5 3.44515
CALHM5 calcium homeostasis modulator family member 5 3.44515
MINAR2 membrane integral NOTCH2 associated receptor 2 3.44515
HAO2 hydroxyacid oxidase 2 (long chain) 3.44515
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase) 3.44515
CLDN16 claudin 16 3.44515
PNLIPRP1 pancreatic lipase-related protein 1 3.44515
TRPC7 transient receptor potential cation channel, subfamily C, member 7 3.44515
FMOD fibromodulin 3.44515
CBY2 chibby family member 2 3.44515
ODAPH odontogenesis associated phosphoprotein 3.44515
H2BW2 H2B.W histone 2 3.44515
TEKTL1 tektin like 1 3.44515
PNMA6F PNMA family member 6F 3.44515
ADAMTSL4-AS2 ADAMTSL4 antisense RNA 2 3.44515
TNS1-AS1 TNS1 antisense RNA 1 3.44515
NOTCH2NLB notch 2 N-terminal like B 3.44515
TMDD1 transmembrane and death domain 1 3.44515
LOC124902436 talanin 3.44515
C20ORF204 chromosome 20 open reading frame 204 3.44515
TBC1D3L TBC1 domain family, member 3L 3.44515
SLC2A7 solute carrier family 2 (facilitated glucose transporter), member 7 3.44515
IQCF1 IQ motif containing F1 3.44515
EXOC3L1 exocyst complex component 3-like 1 3.44515
INSRR insulin receptor-related receptor 3.44515
SH3TC1 SH3 domain and tetratricopeptide repeats 1 3.44515
MIA melanoma inhibitory activity 3.44515
AWAT1 acyl-CoA wax alcohol acyltransferase 1 3.44515
ZIC5 Zic family member 5 3.44515
LRIT3 leucine-rich repeat, immunoglobulin-like and transmembrane domains 3 3.44515
OR2AT4 olfactory receptor, family 2, subfamily AT, member 4 3.44515
CCR9 chemokine (C-C motif) receptor 9 3.44515
TACR2 tachykinin receptor 2 3.44515
PGLYRP1 peptidoglycan recognition protein 1 3.44515
PAPOLB poly(A) polymerase beta (testis specific) 3.44515
XKRX XK, Kell blood group complex subunit-related, X-linked 3.44515
ABCA9 ATP-binding cassette, sub-family A (ABC1), member 9 3.44515
TRPA1 transient receptor potential cation channel, subfamily A, member 1 3.44515
MSGN1 mesogenin 1 3.44515
ZAR1L zygote arrest 1-like 3.44515
PLEK2 pleckstrin 2 3.44515
SAMD11 sterile alpha motif domain containing 11 3.44515
SLC22A25 solute carrier family 22, member 25 3.44515
CCDC83 coiled-coil domain containing 83 3.44515
OR13A1 olfactory receptor, family 13, subfamily A, member 1 3.44515
NACA2 nascent polypeptide-associated complex alpha subunit 2 3.44515
EBF3 early B-cell factor 3 3.44515
FNDC1 fibronectin type III domain containing 1 3.44515
DNAJB13 DnaJ (Hsp40) homolog, subfamily B, member 13 3.44515
SV2C synaptic vesicle glycoprotein 2C 3.44515
RSPH10B2 radial spoke head 10 homolog B2 (Chlamydomonas) 3.44515
PIH1D2 PIH1 domain containing 2 3.44515
THTPA thiamine triphosphatase 3.44515
KLF2 Kruppel-like factor 2 3.44515
KRT3 keratin 3, type II 3.44515
PRF1 perforin 1 (pore forming protein) 3.44515
GP1BA glycoprotein Ib (platelet), alpha polypeptide 3.44515
IL12A interleukin 12A 3.44515
FCN3 ficolin (collagen/fibrinogen domain containing) 3 3.44515
HSPA1L heat shock 70kDa protein 1-like 3.44515
SPATA32 spermatogenesis associated 32 3.44515
OR3A3 olfactory receptor, family 3, subfamily A, member 3 3.44515
CPZ carboxypeptidase Z 3.44515
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7 3.44515
SMIM22 small integral membrane protein 22 3.44515
BMX BMX non-receptor tyrosine kinase 3.44515
AKNAD1 AKNA domain containing 1 3.44515
FAM209B family with sequence similarity 209, member B 3.44515
DRD3 dopamine receptor D3 3.44515
GPR61 G protein-coupled receptor 61 3.44515
IGLL1 immunoglobulin lambda-like polypeptide 1 3.44515
GPR142 G protein-coupled receptor 142 3.44515
KCNA2 potassium channel, voltage gated shaker related subfamily A, member 2 3.44515
CASQ1 calsequestrin 1 (fast-twitch, skeletal muscle) 3.44515
MGP matrix Gla protein 3.44515
SYT5 synaptotagmin V 3.44515
GOLGA8M golgin A8 family, member M 3.44515
PHACTR3 phosphatase and actin regulator 3 3.44515
NT5DC4 5'-nucleotidase domain containing 4 3.44515
RBM20 RNA binding motif protein 20 3.44515
MXRA8 matrix-remodelling associated 8 3.44515
XK X-linked Kx blood group 3.44515
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 3.44515
ISL2 ISL LIM homeobox 2 3.44515
P2RX3 purinergic receptor P2X, ligand gated ion channel, 3 3.44515
PRPH peripherin 3.44515
CHIT1 chitinase 1 (chitotriosidase) 3.44515
PTPN20 protein tyrosine phosphatase, non-receptor type 20 3.44515
ITGA10 integrin, alpha 10 3.44515
IL9R interleukin 9 receptor 3.44515
CFB complement factor B 3.44515
MAPK8IP2 mitogen-activated protein kinase 8 interacting protein 2 3.44515
PF4V1 platelet factor 4 variant 1 3.44515
ST18 suppression of tumorigenicity 18, zinc finger 3.44515
GPRC5D G protein-coupled receptor, class C, group 5, member D 3.44515
TSPYL6 TSPY-like 6 3.44515
DEFB134 defensin, beta 134 3.44515
MYOZ2 myozenin 2 3.44515
DUOXA1 dual oxidase maturation factor 1 3.44515
TRPM2 transient receptor potential cation channel, subfamily M, member 2 3.44515
GRAPL GRB2-related adaptor protein-like 3.44515
IZUMO3 IZUMO family member 3 3.44515
SMCO3 single-pass membrane protein with coiled-coil domains 3 3.44515
IL10RA interleukin 10 receptor, alpha 3.44515
GCM2 glial cells missing homolog 2 (Drosophila) 3.44515
ASMT acetylserotonin O-methyltransferase 3.40015
BIK BCL2-interacting killer (apoptosis-inducing) 3.40015
TGM2 transglutaminase 2 3.40015
GSTM2 glutathione S-transferase mu 2 (muscle) 3.40015
LPIN3 lipin 3 3.40015
IFI6 interferon, alpha-inducible protein 6 3.01329
SEC14L4 SEC14-like 4 (S. cerevisiae) 3.01329
HEATR5B HEAT repeat containing 5B 2.92414
CD63 CD63 molecule 2.85558
DDX39B DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B 2.84655
PDE10A phosphodiesterase 10A 2.73255
DEF6 differentially expressed in FDCP 6 homolog (mouse) 2.72716
TSLIG1 tRNA splicing ligase complex subunit 1 2.7169
ZNF300 zinc finger protein 300 2.71595
LMNTD2 lamin tail domain containing 2 2.5819
SLC13A5 solute carrier family 13 (sodium-dependent citrate transporter), member 5 2.5819
TOPBP1 topoisomerase (DNA) II binding protein 1 2.56063
NAGA N-acetylgalactosaminidase, alpha- 2.53427
CNPY3 canopy FGF signaling regulator 3 2.52939
BLOC1S6 biogenesis of lysosomal organelles complex-1, subunit 6, pallidin 2.52585
TM6SF1 transmembrane 6 superfamily member 1 2.5051
LOX lysyl oxidase 2.5051
MUC20 mucin 20, cell surface associated 2.5051
NUTM2G NUT family member 2G 2.5051
DCLK3 doublecortin-like kinase 3 2.5051
AIFM3 apoptosis-inducing factor, mitochondrion-associated, 3 2.50063
ZNF804A zinc finger protein 804A 2.50063
MBP myelin basic protein 2.47118
DENND4C DENN/MADD domain containing 4C 2.44326
KCNIP1 Kv channel interacting protein 1 2.44326
FAM221B family with sequence similarity 221, member B 2.44233
UNC5D unc-5 homolog D (C. elegans) 2.44233
H2AC8 H2A clustered histone 8 2.42634
GPR141 G protein-coupled receptor 141 2.38657
EBF1 early B-cell factor 1 2.38314
TCEAL5 transcription elongation factor A (SII)-like 5 2.38268
C9ORF78 chromosome 9 open reading frame 78 2.3159
DAPL1 death associated protein-like 1 2.31401
RBL1 retinoblastoma-like 1 2.29837
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 2.28339
DENND2D DENN/MADD domain containing 2D 2.27386
BRCA2 breast cancer 2, early onset 2.2708
DCLRE1A DNA cross-link repair 1A 2.2411
ARHGEF9 Cdc42 guanine nucleotide exchange factor (GEF) 9 2.23786
COP1 COP1 E3 ubiquitin ligase 2.23126
ESD esterase D 2.23126
MADCAM1 mucosal vascular addressin cell adhesion molecule 1 2.19942
PITHD1 PITH (C-terminal proteasome-interacting domain of thioredoxin-like) domain containing 1 2.18576
C19ORF25 chromosome 19 open reading frame 25 2.18425
FLNC filamin C, gamma 2.16702
GUCA1B guanylate cyclase activator 1B (retina) 2.16617
YEATS2 YEATS domain containing 2 2.16617
FMNL3 formin-like 3 2.16617
NDUFV2 NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa 2.16617
TRA2A transformer 2 alpha homolog (Drosophila) 2.15645
TMEM9B TMEM9 domain family, member B 2.14629
LSM1 LSM1, U6 small nuclear RNA associated 2.13011
DNAAF3 dynein, axonemal, assembly factor 3 2.12848
PGP phosphoglycolate phosphatase 2.12175
MRPL35 mitochondrial ribosomal protein L35 2.09045
SPAG17 sperm associated antigen 17 2.08834
HPS5 Hermansky-Pudlak syndrome 5 2.08685
CELSR1 cadherin, EGF LAG seven-pass G-type receptor 1 2.08525
CFAP58 cilia and flagella associated protein 58 2.08525
ITPRIP inositol 1,4,5-trisphosphate receptor interacting protein 2.07744
CD58 CD58 molecule 2.07271
PRX periaxin 2.06378
AKAP7 A kinase (PRKA) anchor protein 7 2.06372
FASTKD2 FAST kinase domains 2 2.06029
ZSCAN25 zinc finger and SCAN domain containing 25 2.06029
HAT1 histone acetyltransferase 1 2.05198
ATL1 atlastin GTPase 1 2.04758
TMEM120B transmembrane protein 120B 2.04341
EPC2 enhancer of polycomb homolog 2 (Drosophila) 2.04166
LAMTOR2 late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 2.02651
HMGN3 high mobility group nucleosomal binding domain 3 2.02651
IRAK2 interleukin-1 receptor-associated kinase 2 2.02046

decreased expression

Symbol Name Standardized Value
NOX3 NADPH oxidase 3 -3.44515
DNAAF19 dynein axonemal assembly factor 19 -3.44515
MPZL2 myelin protein zero-like 2 -3.44515
TRIM58 tripartite motif containing 58 -3.44515
FAM13C family with sequence similarity 13, member C -3.44515
EFEMP2 EGF containing fibulin-like extracellular matrix protein 2 -3.44515
ATG4A autophagy related 4A, cysteine peptidase -3.44515
CD38 CD38 molecule -3.44515
H2AC13 H2A clustered histone 13 -3.44515
LSMEM2 leucine-rich single-pass membrane protein 2 -3.44515
TAMALIN trafficking regulator and scaffold protein tamalin -3.44515
EIF4EBP3 eukaryotic translation initiation factor 4E binding protein 3 -3.44515
E2F2 E2F transcription factor 2 -3.35656
ABCG4 ATP-binding cassette, sub-family G (WHITE), member 4 -3.2785
TTBK1 tau tubulin kinase 1 -3.2785
TRPV6 transient receptor potential cation channel, subfamily V, member 6 -3.2785
GPR20 G protein-coupled receptor 20 -3.2785
ERVFRD-1 endogenous retrovirus group FRD, member 1 -3.2785
ZBTB16 zinc finger and BTB domain containing 16 -3.2785
CD81 CD81 molecule -3.2785
SHBG sex hormone-binding globulin -3.2785
STAP1 signal transducing adaptor family member 1 -3.2785
ANGPTL7 angiopoietin-like 7 -3.2785
SHISA3 shisa family member 3 -3.2785
SNPH syntaphilin -3.2785
GNGT2 guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2 -3.2785
CIMAP1B ciliary microtubule associated protein 1B -3.2785
CDK20 cyclin-dependent kinase 20 -3.2785
ALKAL1 ALK and LTK ligand 1 -3.2785
IFIT1B interferon-induced protein with tetratricopeptide repeats 1B -3.2785
SPINT4 serine peptidase inhibitor, Kunitz type 4 -3.2785
CD48 CD48 molecule -3.2785
GTF2A1L general transcription factor IIA, 1-like -3.2785
IL11 interleukin 11 -3.2785
AGRN agrin -3.18611
DDX24 DEAD (Asp-Glu-Ala-Asp) box helicase 24 -3.18611
SLC25A17 solute carrier family 25 (mitochondrial carrier; peroxisomal membrane protein, 34kDa), member 17 -3.16408
GNB3 guanine nucleotide binding protein (G protein), beta polypeptide 3 -3.15486
FIG4 FIG4 phosphoinositide 5-phosphatase -3.12034
C3 complement component 3 -3.09396
KCNE5 potassium channel, voltage gated subfamily E regulatory beta subunit 5 -3.09396
OR52A1 olfactory receptor, family 52, subfamily A, member 1 -3.08566
CUBN cubilin (intrinsic factor-cobalamin receptor) -3.07521
GDPD5 glycerophosphodiester phosphodiesterase domain containing 5 -3.06763
CLDND2 claudin domain containing 2 -2.99817
CCNH cyclin H -2.9853
PEG10 paternally expressed 10 -2.84655
NSMCE4A non-SMC element 4 homolog A (S. cerevisiae) -2.7964
FBXO22 F-box protein 22 -2.77663
ANKRD23 ankyrin repeat domain 23 -2.74585
COL1A2 collagen, type I, alpha 2 -2.72716
ANO7 anoctamin 7 -2.64905
GAS2L1 growth arrest-specific 2 like 1 -2.64789
SERPINF2 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 -2.63812
LENG9 leukocyte receptor cluster (LRC) member 9 -2.61553
CNN2 calponin 2 -2.60263
TXNL1 thioredoxin-like 1 -2.58614
PHF12 PHD finger protein 12 -2.57166
GNG10 guanine nucleotide binding protein (G protein), gamma 10 -2.54657
TMEM108 transmembrane protein 108 -2.4749
ACKR4 atypical chemokine receptor 4 -2.44326
MTURN maturin, neural progenitor differentiation regulator homolog (Xenopus) -2.44326
ZNF433 zinc finger protein 433 -2.44326
NANOGP8 Nanog homeobox pseudogene 8 -2.44326
FEN1 flap structure-specific endonuclease 1 -2.44248
ART5 ADP-ribosyltransferase 5 -2.42765
SETX senataxin -2.39318
UBE2V2 ubiquitin-conjugating enzyme E2 variant 2 -2.38647
GRK7 G protein-coupled receptor kinase 7 -2.38098
TSR1 TSR1, 20S rRNA accumulation, homolog (S. cerevisiae) -2.3779
DERL2 derlin 2 -2.36341
IL20RB interleukin 20 receptor beta -2.36192
ALG8 ALG8, alpha-1,3-glucosyltransferase -2.3416
SPDYE16 speedy/RINGO cell cycle regulator family member E16 -2.32024
TICAM1 toll-like receptor adaptor molecule 1 -2.32024
INCENP inner centromere protein antigens 135/155kDa -2.23126
HCFC1R1 host cell factor C1 regulator 1 (XPO1 dependent) -2.23126
SEC16A SEC16 homolog A (S. cerevisiae) -2.20644
NIPSNAP3B nipsnap homolog 3B (C. elegans) -2.2031
FTO fat mass and obesity associated -2.18374
LRRC58 leucine rich repeat containing 58 -2.17941
SPG21 spastic paraplegia 21 (autosomal recessive, Mast syndrome) -2.17921
C1ORF202 chromosome 1 open reading frame 202 -2.16617
ADGRB2 adhesion G protein-coupled receptor B2 -2.16431
SYT13 synaptotagmin XIII -2.15601
ZNF611 zinc finger protein 611 -2.15147
PTPRT protein tyrosine phosphatase, receptor type, T -2.13049
MTMR6 myotubularin related protein 6 -2.13049
SLC45A1 solute carrier family 45, member 1 -2.13011
CCDC68 coiled-coil domain containing 68 -2.13011
LEF1 lymphoid enhancer-binding factor 1 -2.12371
PLPPR1 phospholipid phosphatase related 1 -2.11195
RBP5 retinol binding protein 5, cellular -2.08685
MAN1C1 mannosidase, alpha, class 1C, member 1 -2.08685
CRACR2A calcium release activated channel regulator 2A -2.07271
GSTCD glutathione S-transferase, C-terminal domain containing -2.07082
ALDH3A2 aldehyde dehydrogenase 3 family, member A2 -2.06284
SVOPL SVOP-like -2.06029
ZNF225 zinc finger protein 225 -2.06029
INPP5F inositol polyphosphate-5-phosphatase F -2.05045
ALDH16A1 aldehyde dehydrogenase 16 family, member A1 -2.04486
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) -2.01867
ARHGEF40 Rho guanine nucleotide exchange factor (GEF) 40 -2.01867
RFX3 regulatory factor X, 3 (influences HLA class II expression) -2.00176