| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | cystathionine-beta-synthase|The protein encoded by this gene acts as a homotetramer to catalyze the conversion of homocysteine to cystathionine, the first step in the transsulfuration pathway. The encoded protein is allosterically activated by adenosyl-methionine and uses pyridoxal phosphate as a cofactor. Defects in this gene can cause cystathionine beta-synthase deficiency (CBSD), which can lead to homocystinuria. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, May 2010] (NCBI Entrez Gene Database, 875) |
| External Link | https://ncbi.nlm.nih.gov/gene/875 |
| Similar Terms | |
| Downloads & Tools |
497 genes differentially expressed following the CBS gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ZNF589 | zinc finger protein 589 | 0.0117664 |
| S100A8 | S100 calcium binding protein A8 | 0.0114496 |
| CA2 | carbonic anhydrase II | 0.0110869 |
| ABHD4 | abhydrolase domain containing 4 | 0.0106869 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | 0.0103888 |
| MMP12 | matrix metallopeptidase 12 | 0.0103471 |
| S100A9 | S100 calcium binding protein A9 | 0.0101108 |
| RAB25 | RAB25, member RAS oncogene family | 0.00978445 |
| BLNK | B-cell linker | 0.0095891 |
| HSD11B1 | hydroxysteroid (11-beta) dehydrogenase 1 | 0.00935611 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.00932631 |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 | 0.00929595 |
| MME | membrane metallo-endopeptidase | 0.00914525 |
| MNDA | myeloid cell nuclear differentiation antigen | 0.00898339 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 | 0.00896825 |
| SPON2 | spondin 2, extracellular matrix protein | 0.0088307 |
| CLEC11A | C-type lectin domain family 11, member A | 0.00864662 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) | 0.00864391 |
| MYRF | myelin regulatory factor | 0.0086406 |
| GLUL | glutamate-ammonia ligase | 0.00857003 |
| PHLDA2 | pleckstrin homology-like domain, family A, member 2 | 0.00854063 |
| TPD52L1 | tumor protein D52-like 1 | 0.00849117 |
| C1R | complement component 1, r subcomponent | 0.00842984 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | 0.0084152 |
| CDO1 | cysteine dioxygenase type 1 | 0.00834525 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.00826425 |
| PRDX2 | peroxiredoxin 2 | 0.0080563 |
| AQP9 | aquaporin 9 | 0.00800939 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase | 0.00800268 |
| S100A12 | S100 calcium binding protein A12 | 0.00786087 |
| ESR1 | estrogen receptor 1 | 0.00784563 |
| HOXC6 | homeobox C6 | 0.00783638 |
| CARHSP1 | calcium regulated heat stable protein 1, 24kDa | 0.00776043 |
| DACT1 | dishevelled-binding antagonist of beta-catenin 1 | 0.00774856 |
| TFF3 | trefoil factor 3 (intestinal) | 0.0077038 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | 0.00766442 |
| TMEM63A | transmembrane protein 63A | 0.00754597 |
| MMP9 | matrix metallopeptidase 9 | 0.0075155 |
| SH3GL3 | SH3-domain GRB2-like 3 | 0.00751279 |
| AIF1 | allograft inflammatory factor 1 | 0.00748711 |
| BTF3P11 | basic transcription factor 3 pseudogene 11 | 0.00747805 |
| GUSBP3 | glucuronidase, beta pseudogene 3 | 0.00747337 |
| UGT2B15 | UDP glucuronosyltransferase 2 family, polypeptide B15 | 0.00746767 |
| CKS2 | CDC28 protein kinase regulatory subunit 2 | 0.00745544 |
| CYP2C9 | cytochrome P450, family 2, subfamily C, polypeptide 9 | 0.00733538 |
| HNRNPL | heterogeneous nuclear ribonucleoprotein L | 0.00730651 |
| ESRP1 | epithelial splicing regulatory protein 1 | 0.00730354 |
| CD81 | CD81 molecule | 0.00727569 |
| CYBB | cytochrome b-245, beta polypeptide | 0.00725616 |
| PAK1 | p21 protein (Cdc42/Rac)-activated kinase 1 | 0.00724019 |
| RARRES2 | retinoic acid receptor responder (tazarotene induced) 2 | 0.00719653 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.00712209 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.00709977 |
| CSRP3 | cysteine and glycine-rich protein 3 (cardiac LIM protein) | 0.00707307 |
| C1QTNF3 | C1q and tumor necrosis factor related protein 3 | 0.0070681 |
| HEPH | hephaestin | 0.00701753 |
| HP | haptoglobin | 0.00699792 |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 | 0.00699453 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | 0.00692919 |
| SLC5A6 | solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 | 0.00686403 |
| SIAH2 | siah E3 ubiquitin protein ligase 2 | 0.00682367 |
| LYN | LYN proto-oncogene, Src family tyrosine kinase | 0.00681002 |
| NUSAP1 | nucleolar and spindle associated protein 1 | 0.00680304 |
| LYZ | lysozyme | 0.00675605 |
| PXMP2 | peroxisomal membrane protein 2, 22kDa | 0.00673142 |
| NANOG | Nanog homeobox | 0.00670763 |
| IRF8 | interferon regulatory factor 8 | 0.00668816 |
| PXDN | peroxidasin | 0.00665606 |
| CYP2E1 | cytochrome P450, family 2, subfamily E, polypeptide 1 | 0.00664756 |
| PALLD | palladin, cytoskeletal associated protein | 0.00662908 |
| MYB | v-myb avian myeloblastosis viral oncogene homolog | 0.0065409 |
| CAMP | cathelicidin antimicrobial peptide | 0.00651185 |
| IL1RN | interleukin 1 receptor antagonist | 0.00640509 |
| CD53 | CD53 molecule | 0.00637053 |
| MINDY1 | MINDY lysine 48 deubiquitinase 1 | 0.00635769 |
| PRKCB | protein kinase C, beta | 0.00633668 |
| IL17RB | interleukin 17 receptor B | 0.00629301 |
| MPC2 | mitochondrial pyruvate carrier 2 | 0.00627401 |
| PLEK | pleckstrin | 0.00621002 |
| TMEM176B | transmembrane protein 176B | 0.00619008 |
| HAUS2 | HAUS augmin-like complex, subunit 2 | 0.00618223 |
| KLK12 | kallikrein-related peptidase 12 | 0.00617297 |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 | 0.00616412 |
| ERAP2 | endoplasmic reticulum aminopeptidase 2 | 0.00614145 |
| CXCL12 | chemokine (C-X-C motif) ligand 12 | 0.00613726 |
| SPON1 | spondin 1, extracellular matrix protein | 0.00613531 |
| RESF1 | retroelement silencing factor 1 | 0.00607924 |
| RXYLT1 | ribitol xylosyltransferase 1 | 0.00607755 |
| BST2 | bone marrow stromal cell antigen 2 | 0.00606154 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.00602289 |
| ASRGL1 | asparaginase like 1 | 0.00598461 |
| EHHADH | enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase | 0.00598453 |
| ATG3 | autophagy related 3 | 0.00597144 |
| FCGR3B | Fc fragment of IgG, low affinity IIIb, receptor (CD16b) | 0.00594579 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 | 0.00591409 |
| POU5F1B | POU class 5 homeobox 1B | 0.0058955 |
| UBXN7 | UBX domain protein 7 | 0.00587444 |
| RBBP7 | retinoblastoma binding protein 7 | 0.00587054 |
| NRCAM | neuronal cell adhesion molecule | 0.00586999 |
| THY1 | Thy-1 cell surface antigen | 0.00583519 |
| DSE | dermatan sulfate epimerase | 0.00580127 |
| RAB32 | RAB32, member RAS oncogene family | 0.00580051 |
| F13A1 | coagulation factor XIII, A1 polypeptide | 0.0057919 |
| MCUB | mitochondrial calcium uniporter dominant negative subunit beta | 0.00578671 |
| PSMB9 | proteasome (prosome, macropain) subunit, beta type, 9 | 0.00578634 |
| SDC2 | syndecan 2 | 0.00578268 |
| AK4 | adenylate kinase 4 | 0.00576703 |
| SLC4A1 | solute carrier family 4 (anion exchanger), member 1 (Diego blood group) | 0.00576362 |
| GBP2 | guanylate binding protein 2, interferon-inducible | 0.00576188 |
| FBP1 | fructose-1,6-bisphosphatase 1 | 0.0057608 |
| DIP2A | DIP2 disco-interacting protein 2 homolog A (Drosophila) | 0.00574825 |
| CDC42 | cell division cycle 42 | 0.00574533 |
| CLDND1 | claudin domain containing 1 | 0.00574296 |
| ITGB4 | integrin, beta 4 | 0.00573198 |
| RAB40B | RAB40B, member RAS oncogene family | 0.00571806 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.00571752 |
| GATM | glycine amidinotransferase (L-arginine:glycine amidinotransferase) | 0.00571315 |
| ALDOB | aldolase B, fructose-bisphosphate | 0.00570337 |
| CEP57 | centrosomal protein 57kDa | 0.00568455 |
| DIXDC1 | DIX domain containing 1 | 0.00568448 |
| LSM3 | LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae) | 0.00567251 |
| LY86 | lymphocyte antigen 86 | 0.00566945 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | 0.00566695 |
| TOX3 | TOX high mobility group box family member 3 | 0.00566517 |
| ZNF611 | zinc finger protein 611 | 0.00565359 |
| MPHOSPH8 | M-phase phosphoprotein 8 | 0.00565159 |
| ARMC1 | armadillo repeat containing 1 | 0.00564225 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.00563997 |
| POU5F1P3 | POU class 5 homeobox 1 pseudogene 3 | 0.00563767 |
| SH3YL1 | SH3 and SYLF domain containing 1 | 0.0056329 |
| MOXD1 | monooxygenase, DBH-like 1 | 0.00562893 |
| THOC7 | THO complex 7 | 0.00559624 |
| PSMC3 | proteasome (prosome, macropain) 26S subunit, ATPase, 3 | 0.00557528 |
| SERINC5 | serine incorporator 5 | 0.00556532 |
| DEPTOR | DEP domain containing MTOR-interacting protein | 0.00555192 |
| GOLT1B | golgi transport 1B | 0.00553327 |
| F12 | coagulation factor XII (Hageman factor) | 0.00551235 |
| MPO | myeloperoxidase | 0.0055061 |
| TRIM22 | tripartite motif containing 22 | 0.00549847 |
| KLK10 | kallikrein-related peptidase 10 | 0.00548784 |
| PSME2 | proteasome (prosome, macropain) activator subunit 2 (PA28 beta) | 0.00547472 |
| NCK1 | NCK adaptor protein 1 | 0.00545753 |
| ALOX5AP | arachidonate 5-lipoxygenase-activating protein | 0.0054343 |
| PCLAF | PCNA clamp associated factor | 0.00542802 |
| CD52 | CD52 molecule | 0.00542469 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) | 0.00542364 |
| TFF1 | trefoil factor 1 | 0.00541855 |
| MTERF3 | mitochondrial transcription termination factor 3 | 0.00540105 |
| FILIP1L | filamin A interacting protein 1-like | 0.00539014 |
| EIF5A | eukaryotic translation initiation factor 5A | 0.00538289 |
| GPR37 | G protein-coupled receptor 37 (endothelin receptor type B-like) | 0.00537484 |
| PUF60 | poly-U binding splicing factor 60KDa | 0.00535485 |
| SELENOT | selenoprotein T | 0.00533003 |
| AMFR | autocrine motility factor receptor, E3 ubiquitin protein ligase | 0.00532668 |
| ZNF721 | zinc finger protein 721 | 0.00531081 |
| IGSF6 | immunoglobulin superfamily, member 6 | 0.00530369 |
| PI3 | peptidase inhibitor 3, skin-derived | 0.00528106 |
| CD200 | CD200 molecule | 0.00527734 |
| GZMB | granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) | 0.00527172 |
| RASSF1 | Ras association (RalGDS/AF-6) domain family member 1 | 0.0052593 |
| SFRP4 | secreted frizzled-related protein 4 | 0.0052504 |
| HPX | hemopexin | 0.00524471 |
| HBD | hemoglobin, delta | 0.00523947 |
| COL10A1 | collagen, type X, alpha 1 | 0.00523178 |
| CD3E | CD3e molecule, epsilon (CD3-TCR complex) | 0.00521042 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | 0.00518074 |
| ADI1 | acireductone dioxygenase 1 | 0.00518007 |
| KLK13 | kallikrein-related peptidase 13 | 0.00516721 |
| RAMP1 | receptor (G protein-coupled) activity modifying protein 1 | 0.005166 |
| APOC1 | apolipoprotein C-I | 0.00516332 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | 0.00516321 |
| INSR | insulin receptor | 0.00515089 |
| SLC1A1 | solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 | 0.00514514 |
| RAB4A | RAB4A, member RAS oncogene family | 0.00514389 |
| C7 | complement component 7 | 0.00513645 |
| KLK6 | kallikrein-related peptidase 6 | 0.0051319 |
| NCF2 | neutrophil cytosolic factor 2 | 0.00512966 |
| LSM7 | LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae) | 0.00512678 |
| CEPT1 | choline/ethanolamine phosphotransferase 1 | 0.00512676 |
| CHN2 | chimerin 2 | 0.00511876 |
| NUTF2 | nuclear transport factor 2 | 0.00511844 |
| CD99 | CD99 molecule | 0.00511246 |
| ZNF665 | zinc finger protein 665 | 0.00510949 |
| SNRPD1 | small nuclear ribonucleoprotein D1 polypeptide 16kDa | 0.00509106 |
| PSMB10 | proteasome (prosome, macropain) subunit, beta type, 10 | 0.00508521 |
| LCK | LCK proto-oncogene, Src family tyrosine kinase | 0.00508239 |
| CALB1 | calbindin 1, 28kDa | 0.00507738 |
| GUCY2C | guanylate cyclase 2C | 0.0050772 |
| C4BPA | complement component 4 binding protein, alpha | 0.00507332 |
| ZNF160 | zinc finger protein 160 | 0.00505939 |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D | 0.00505916 |
| GBAP1 | glucosidase, beta, acid pseudogene 1 | 0.00505087 |
| APCS | amyloid P component, serum | 0.00503826 |
| TNFSF13 | tumor necrosis factor (ligand) superfamily, member 13 | 0.00503639 |
| TRMT2B | tRNA methyltransferase 2 homolog B (S. cerevisiae) | 0.00503366 |
| PDZK1IP1 | PDZK1 interacting protein 1 | 0.00502933 |
| UGT2B28 | UDP glucuronosyltransferase 2 family, polypeptide B28 | 0.00502355 |
| SULF1 | sulfatase 1 | 0.00502184 |
| DLST | dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) | 0.00499937 |
| PNN | pinin, desmosome associated protein | 0.00499642 |
| MARCO | macrophage receptor with collagenous structure | 0.00498674 |
| ADAP1 | ArfGAP with dual PH domains 1 | 0.00498063 |
| ACTB | actin, beta | 0.00497806 |
| FEZ1 | fasciculation and elongation protein zeta 1 (zygin I) | 0.00497526 |
| NUDT11 | nudix (nucleoside diphosphate linked moiety X)-type motif 11 | 0.00494161 |
| LGALS4 | lectin, galactoside-binding, soluble, 4 | 0.00493089 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) | 0.00493064 |
| ZNF430 | zinc finger protein 430 | 0.00491931 |
| ACTN1 | actinin, alpha 1 | 0.00490459 |
| KCNMB4 | potassium channel subfamily M regulatory beta subunit 4 | 0.00490287 |
| HSD17B6 | hydroxysteroid (17-beta) dehydrogenase 6 | 0.00490032 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | 0.0048793 |
| CALD1 | caldesmon 1 | 0.00486731 |
| FPR1 | formyl peptide receptor 1 | 0.00486203 |
| LSM2 | LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae) | 0.00485589 |
| CUX1 | cut-like homeobox 1 | 0.00485402 |
| RASA4 | RAS p21 protein activator 4 | 0.00485246 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | 0.00485182 |
| RNASE2 | ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) | 0.00483403 |
| CTSS | cathepsin S | 0.00481924 |
| CDK14 | cyclin-dependent kinase 14 | 0.00481335 |
| ABHD18 | abhydrolase domain containing 18 | 0.00481179 |
| DSP | desmoplakin | 0.00480746 |
| INSIG1 | insulin induced gene 1 | 0.004802 |
| IFI30 | interferon, gamma-inducible protein 30 | 0.00479704 |
| KNG1 | kininogen 1 | 0.00479452 |
| BCL6 | B-cell CLL/lymphoma 6 | 0.00478527 |
| CFHR2 | complement factor H-related 2 | 0.0047796 |
| MS4A1 | membrane-spanning 4-domains, subfamily A, member 1 | 0.00476717 |
| CD2 | CD2 molecule | 0.00476236 |
| ME3 | malic enzyme 3, NADP(+)-dependent, mitochondrial | 0.00475297 |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit | 0.00474869 |
| EPHA1 | EPH receptor A1 | 0.00474571 |
| RHCG | Rh family, C glycoprotein | 0.0047406 |
| RBBP4 | retinoblastoma binding protein 4 | 0.00474038 |
| CYP4F2 | cytochrome P450, family 4, subfamily F, polypeptide 2 | 0.00473325 |
| PRR11 | proline rich 11 | 0.00472322 |
| PARP2 | poly (ADP-ribose) polymerase 2 | 0.00472306 |
| GLYAT | glycine-N-acyltransferase | 0.00471911 |
| INHBA | inhibin, beta A | 0.00470938 |
| F5 | coagulation factor V (proaccelerin, labile factor) | 0.00470762 |
| HTR2B | 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled | 0.00470586 |
| PSME1 | proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) | 0.00470003 |
| VSNL1 | visinin-like 1 | 0.00469562 |
| MAGT1 | magnesium transporter 1 | 0.00468321 |
| HEBP2 | heme binding protein 2 | 0.00467801 |
| DDR2 | discoidin domain receptor tyrosine kinase 2 | 0.00467782 |
| MAP7 | microtubule-associated protein 7 | 0.0046735 |
| TMPRSS4 | transmembrane protease, serine 4 | 0.00466685 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0141533 |
| GNAS | GNAS complex locus | -0.0136366 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0119031 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0117232 |
| POSTN | periostin, osteoblast specific factor | -0.0113874 |
| KCNJ16 | potassium channel, inwardly rectifying subfamily J, member 16 | -0.0112812 |
| A2M | alpha-2-macroglobulin | -0.0110189 |
| AQP3 | aquaporin 3 (Gill blood group) | -0.0109614 |
| PEG10 | paternally expressed 10 | -0.010849 |
| MEF2C | myocyte enhancer factor 2C | -0.0107204 |
| KRT14 | keratin 14, type I | -0.0106856 |
| FABP4 | fatty acid binding protein 4, adipocyte | -0.0106851 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.0105836 |
| MAGEA3 | melanoma antigen family A3 | -0.0104748 |
| VWF | von Willebrand factor | -0.0100595 |
| PIP | prolactin-induced protein | -0.00955584 |
| APOBEC3B | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B | -0.00948834 |
| SYNM | synemin, intermediate filament protein | -0.00924269 |
| IL13RA2 | interleukin 13 receptor, alpha 2 | -0.0092032 |
| APOD | apolipoprotein D | -0.00895657 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | -0.00888222 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.00886017 |
| RGS5 | regulator of G-protein signaling 5 | -0.00876603 |
| HSPA1A | heat shock 70kDa protein 1A | -0.00874384 |
| SCGB2A2 | secretoglobin, family 2A, member 2 | -0.00865931 |
| SVIL | supervillin | -0.00864129 |
| CHP1 | calcineurin-like EF-hand protein 1 | -0.0086354 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.00840025 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase | -0.00839449 |
| ADGRF5 | adhesion G protein-coupled receptor F5 | -0.00838747 |
| ANGPT2 | angiopoietin 2 | -0.00831334 |
| DLK1 | delta-like 1 homolog (Drosophila) | -0.00824307 |
| KRT5 | keratin 5, type II | -0.00824063 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | -0.00808404 |
| LAPTM4B | lysosomal protein transmembrane 4 beta | -0.00803468 |
| GIMAP6 | GTPase, IMAP family member 6 | -0.00800665 |
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 | -0.00793368 |
| KRT17 | keratin 17, type I | -0.00792586 |
| STK10 | serine/threonine kinase 10 | -0.00790464 |
| AQP1 | aquaporin 1 (Colton blood group) | -0.00786021 |
| PFN2 | profilin 2 | -0.00780344 |
| JCHAIN | joining chain of multimeric IgA and IgM | -0.00779784 |
| TPPP3 | tubulin polymerization-promoting protein family member 3 | -0.00778016 |
| FCGBP | Fc fragment of IgG binding protein | -0.00770982 |
| CTAG2 | cancer/testis antigen 2 | -0.00766418 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.00762038 |
| MLF1 | myeloid leukemia factor 1 | -0.00757709 |
| HEY1 | hes-related family bHLH transcription factor with YRPW motif 1 | -0.00756581 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.00755114 |
| SRPX | sushi-repeat containing protein, X-linked | -0.0075231 |
| LAMP3 | lysosomal-associated membrane protein 3 | -0.00751845 |
| MMRN1 | multimerin 1 | -0.00748722 |
| SIK1 | salt-inducible kinase 1 | -0.00733661 |
| KYNU | kynureninase | -0.00729047 |
| RUNX3 | runt-related transcription factor 3 | -0.00712031 |
| GNG11 | guanine nucleotide binding protein (G protein), gamma 11 | -0.00709873 |
| TGFB1 | transforming growth factor, beta 1 | -0.00709707 |
| ACTA1 | actin, alpha 1, skeletal muscle | -0.00697822 |
| PGF | placental growth factor | -0.00697584 |
| TACC2 | transforming, acidic coiled-coil containing protein 2 | -0.00691231 |
| TNNC1 | troponin C type 1 (slow) | -0.00684655 |
| NIBAN1 | niban apoptosis regulator 1 | -0.00682752 |
| JAG1 | jagged 1 | -0.00679196 |
| PCOLCE2 | procollagen C-endopeptidase enhancer 2 | -0.00677169 |
| LRRC17 | leucine rich repeat containing 17 | -0.00673818 |
| MAGEA12 | melanoma antigen family A12 | -0.00671281 |
| STC1 | stanniocalcin 1 | -0.00668901 |
| KLHL41 | kelch-like family member 41 | -0.00667504 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) | -0.00664287 |
| SH2B3 | SH2B adaptor protein 3 | -0.00659872 |
| GPX3 | glutathione peroxidase 3 | -0.00658905 |
| PTP4A3 | protein tyrosine phosphatase type IVA, member 3 | -0.00656727 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.00654502 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.00652351 |
| ASXL2 | additional sex combs like transcriptional regulator 2 | -0.006402 |
| IGSF3 | immunoglobulin superfamily, member 3 | -0.00639218 |
| MYOT | myotilin | -0.00637876 |
| COL9A2 | collagen, type IX, alpha 2 | -0.00633518 |
| TTN | titin | -0.00633211 |
| TNNT3 | troponin T type 3 (skeletal, fast) | -0.00631801 |
| HRASLS | HRAS-like suppressor | -0.00629795 |
| L1CAM | L1 cell adhesion molecule | -0.00622965 |
| MAGEA4 | melanoma antigen family A4 | -0.0062131 |
| RRAD | Ras-related associated with diabetes | -0.00621026 |
| CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 | -0.00619607 |
| OLFML2A | olfactomedin-like 2A | -0.00617215 |
| GGT1 | gamma-glutamyltransferase 1 | -0.00616718 |
| APOLD1 | apolipoprotein L domain containing 1 | -0.00607279 |
| KRT81 | keratin 81, type II | -0.00606994 |
| PMP22 | peripheral myelin protein 22 | -0.00606749 |
| GALC | galactosylceramidase | -0.00606281 |
| FRZB | frizzled-related protein | -0.00604272 |
| MXI1 | MAX interactor 1, dimerization protein | -0.00602231 |
| CKM | creatine kinase, muscle | -0.00601743 |
| MB | myoglobin | -0.0060063 |
| COL3A1 | collagen, type III, alpha 1 | -0.00600549 |
| ABCC4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 | -0.0059816 |
| ZSCAN18 | zinc finger and SCAN domain containing 18 | -0.00596831 |
| FNDC3B | fibronectin type III domain containing 3B | -0.00596552 |
| ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | -0.00596192 |
| MALL | mal, T-cell differentiation protein-like | -0.00595772 |
| INAVA | innate immunity activator | -0.00594728 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | -0.00594073 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.00593257 |
| PDGFD | platelet derived growth factor D | -0.0059204 |
| RYR1 | ryanodine receptor 1 (skeletal) | -0.00578415 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.00578275 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | -0.00577936 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.00577882 |
| KRT15 | keratin 15, type I | -0.0057586 |
| BCHE | butyrylcholinesterase | -0.00575377 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | -0.00572117 |
| MYH2 | myosin, heavy chain 2, skeletal muscle, adult | -0.0057108 |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 | -0.0057058 |
| PRR4 | proline rich 4 (lacrimal) | -0.00567437 |
| AHR | aryl hydrocarbon receptor | -0.00567428 |
| TMED3 | transmembrane emp24 protein transport domain containing 3 | -0.0056364 |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) | -0.00562515 |
| G6PD | glucose-6-phosphate dehydrogenase | -0.00561961 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.00559221 |
| LEPROTL1 | leptin receptor overlapping transcript-like 1 | -0.00558103 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0055605 |
| TNNC2 | troponin C type 2 (fast) | -0.00554745 |
| SERPINI1 | serpin peptidase inhibitor, clade I (neuroserpin), member 1 | -0.00553706 |
| EMP1 | epithelial membrane protein 1 | -0.00551378 |
| MET | MET proto-oncogene, receptor tyrosine kinase | -0.00550188 |
| SELE | selectin E | -0.00549676 |
| PTN | pleiotrophin | -0.00548404 |
| TMEM255A | transmembrane protein 255A | -0.00548185 |
| ZNF395 | zinc finger protein 395 | -0.00546664 |
| MGP | matrix Gla protein | -0.00545546 |
| USP13 | ubiquitin specific peptidase 13 (isopeptidase T-3) | -0.00544766 |
| RPN2 | ribophorin II | -0.00543186 |
| SPARCL1 | SPARC-like 1 (hevin) | -0.00543047 |
| CLDN5 | claudin 5 | -0.0054219 |
| EGFL6 | EGF-like-domain, multiple 6 | -0.00541345 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | -0.00541186 |
| SIX1 | SIX homeobox 1 | -0.00538971 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.00538491 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.00538264 |
| GIMAP4 | GTPase, IMAP family member 4 | -0.00537269 |
| LRP2 | low density lipoprotein receptor-related protein 2 | -0.00537046 |
| EFNB2 | ephrin-B2 | -0.00536803 |
| SFRP1 | secreted frizzled-related protein 1 | -0.00535692 |
| VIM | vimentin | -0.00533666 |
| MYBPC1 | myosin binding protein C, slow type | -0.00532699 |
| MAGED1 | melanoma antigen family D1 | -0.00531219 |
| HMGN3 | high mobility group nucleosomal binding domain 3 | -0.00530853 |
| TNNI2 | troponin I type 2 (skeletal, fast) | -0.00530605 |
| KLHDC10 | kelch domain containing 10 | -0.00530595 |
| KLF2 | Kruppel-like factor 2 | -0.00527676 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.00526837 |
| COL9A3 | collagen, type IX, alpha 3 | -0.0052664 |
| LIFR | leukemia inhibitory factor receptor alpha | -0.00524969 |
| EDNRA | endothelin receptor type A | -0.00524853 |
| AMDHD2 | amidohydrolase domain containing 2 | -0.00524181 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.00523714 |
| SOX11 | SRY (sex determining region Y)-box 11 | -0.00522876 |
| ELK3 | ELK3, ETS-domain protein (SRF accessory protein 2) | -0.00522615 |
| DGKD | diacylglycerol kinase, delta 130kDa | -0.00520943 |
| TSPAN7 | tetraspanin 7 | -0.0052094 |
| WFDC2 | WAP four-disulfide core domain 2 | -0.00516487 |
| TNNI1 | troponin I type 1 (skeletal, slow) | -0.00516301 |
| DYNLL1 | dynein, light chain, LC8-type 1 | -0.00515817 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | -0.00514855 |
| NETO2 | neuropilin (NRP) and tolloid (TLL)-like 2 | -0.00514821 |
| STATH | statherin | -0.00513355 |
| S100A2 | S100 calcium binding protein A2 | -0.00513287 |
| TKTL1 | transketolase-like 1 | -0.00512296 |
| MID1 | midline 1 | -0.00510434 |
| CCN2 | cellular communication network factor 2 | -0.00510208 |
| FOXC1 | forkhead box C1 | -0.00510104 |
| TGFA | transforming growth factor, alpha | -0.00509355 |
| ANOS1 | anosmin 1 | -0.00509161 |
| MYH10 | myosin, heavy chain 10, non-muscle | -0.00506909 |
| KCNS3 | potassium voltage-gated channel, modifier subfamily S, member 3 | -0.00505658 |
| CREM | cAMP responsive element modulator | -0.00505079 |
| DUSP3 | dual specificity phosphatase 3 | -0.00505049 |
| FBLN2 | fibulin 2 | -0.00504845 |
| SNAP25 | synaptosomal-associated protein, 25kDa | -0.00504624 |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) | -0.00503058 |
| MYBPC2 | myosin binding protein C, fast type | -0.00502791 |
| SLC38A1 | solute carrier family 38, member 1 | -0.00502774 |
| PRAME | preferentially expressed antigen in melanoma | -0.00501521 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.00501276 |
| IGFBP1 | insulin-like growth factor binding protein 1 | -0.00500898 |
| GCG | glucagon | -0.00499975 |
| ALDH3B1 | aldehyde dehydrogenase 3 family, member B1 | -0.00498637 |
| INHBB | inhibin, beta B | -0.00498596 |
| MAP1B | microtubule-associated protein 1B | -0.00498015 |
| CLEC2B | C-type lectin domain family 2, member B | -0.00495655 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | -0.00495363 |
| CD93 | CD93 molecule | -0.00494842 |
| PKIA | protein kinase (cAMP-dependent, catalytic) inhibitor alpha | -0.0049324 |
| ASB9 | ankyrin repeat and SOCS box containing 9 | -0.00493197 |
| SMARCA1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 | -0.00492629 |
| GOLGA8H | golgin A8 family, member H | -0.00492533 |
| CALML5 | calmodulin-like 5 | -0.00492295 |
| BTBD3 | BTB (POZ) domain containing 3 | -0.00491891 |
| DNMBP | dynamin binding protein | -0.00490384 |
| ITIH5 | inter-alpha-trypsin inhibitor heavy chain family, member 5 | -0.00489375 |
| OLFM1 | olfactomedin 1 | -0.00487551 |
| CX3CL1 | chemokine (C-X3-C motif) ligand 1 | -0.00486336 |
| MSMB | microseminoprotein, beta- | -0.00486272 |
| TSPAN4 | tetraspanin 4 | -0.00484893 |
| TCTA | T-cell leukemia translocation altered | -0.00483193 |
| FN1 | fibronectin 1 | -0.00483122 |
| HHLA2 | HERV-H LTR-associating 2 | -0.00483034 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | -0.00482496 |
| DHDDS | dehydrodolichyl diphosphate synthase | -0.004817 |
| QSOX1 | quiescin Q6 sulfhydryl oxidase 1 | -0.00481407 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.00481079 |
| NR0B1 | nuclear receptor subfamily 0, group B, member 1 | -0.00480231 |
| MARCKSL1 | MARCKS-like 1 | -0.00480056 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | -0.00478267 |
| CDH5 | cadherin 5, type 2 (vascular endothelium) | -0.00478179 |
| WWC1 | WW and C2 domain containing 1 | -0.00478012 |
| RAP2A | RAP2A, member of RAS oncogene family | -0.00477942 |
| PCGF2 | polycomb group ring finger 2 | -0.0047774 |
| DCX | doublecortin | -0.00477624 |
| GOLM1 | golgi membrane protein 1 | -0.00477245 |
| AKR1C3 | aldo-keto reductase family 1, member C3 | -0.00477043 |
| NBEA | neurobeachin | -0.00476168 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.00475062 |
| IGLL1 | immunoglobulin lambda-like polypeptide 1 | -0.00473245 |
| SRI | sorcin | -0.00473241 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | -0.00472042 |
| MYL1 | myosin, light chain 1, alkali; skeletal, fast | -0.00469777 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.00467839 |
| RRBP1 | ribosome binding protein 1 | -0.00466577 |
| KIF5C | kinesin family member 5C | -0.00465813 |
| SCGB1A1 | secretoglobin, family 1A, member 1 (uteroglobin) | -0.00465218 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.00464823 |
| OAT | ornithine aminotransferase | -0.00464479 |
| LDOC1 | leucine zipper, down-regulated in cancer 1 | -0.00464213 |
| ACTA2 | actin, alpha 2, smooth muscle, aorta | -0.00464099 |
| MYL2 | myosin, light chain 2, regulatory, cardiac, slow | -0.00463167 |
| PCLO | piccolo presynaptic cytomatrix protein | -0.00460898 |
| MS4A12 | membrane-spanning 4-domains, subfamily A, member 12 | -0.00460428 |
| CLCN4 | chloride channel, voltage-sensitive 4 | -0.00460324 |
| CALCRL | calcitonin receptor-like | -0.00460066 |
| SUSD5 | sushi domain containing 5 | -0.00459504 |
| ESM1 | endothelial cell-specific molecule 1 | -0.00459442 |
| PLXNA1 | plexin A1 | -0.00459244 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.00458887 |
| FLI1 | Fli-1 proto-oncogene, ETS transcription factor | -0.00457993 |
| CKAP4 | cytoskeleton-associated protein 4 | -0.00457884 |
| WASL | Wiskott-Aldrich syndrome-like | -0.00457857 |
