CC2D2A Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description coiled-coil and C2 domain containing 2A|This gene encodes a coiled-coil and calcium binding domain protein that appears to play a critical role in cilia formation. Mutations in this gene cause Meckel syndrome type 6, as well as Joubert syndrome type 9. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009] (NCBI Entrez Gene Database, 57545)
External Link https://ncbi.nlm.nih.gov/gene/57545
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Genes

498 genes differentially expressed following the CC2D2A gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
HSPA1A heat shock 70kDa protein 1A 0.0203506
S100A8 S100 calcium binding protein A8 0.0176953
S100A9 S100 calcium binding protein A9 0.0164737
STXBP2 syntaxin binding protein 2 0.0157222
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 0.0139316
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 0.013909
COG7 component of oligomeric golgi complex 7 0.0137764
SLPI secretory leukocyte peptidase inhibitor 0.0136858
IL32 interleukin 32 0.0127054
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D 0.0122385
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 0.0120086
CXCL8 chemokine (C-X-C motif) ligand 8 0.0119993
S100A7 S100 calcium binding protein A7 0.0118503
TNNT1 troponin T type 1 (skeletal, slow) 0.0117936
MBOAT7 membrane bound O-acyltransferase domain containing 7 0.0117248
MARCKS myristoylated alanine-rich protein kinase C substrate 0.0114583
METRN meteorin, glial cell differentiation regulator 0.0111376
ANXA1 annexin A1 0.011095
ANXA3 annexin A3 0.0110128
EGR1 early growth response 1 0.0109707
HSPH1 heat shock 105kDa/110kDa protein 1 0.0107194
KRT7 keratin 7, type II 0.0106047
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 0.0105456
KRT23 keratin 23, type I 0.0105242
RIPOR2 RHO family interacting cell polarization regulator 2 0.0104308
RRAGD Ras-related GTP binding D 0.0104273
ZNF652 zinc finger protein 652 0.010243
GUSBP3 glucuronidase, beta pseudogene 3 0.0100942
LY96 lymphocyte antigen 96 0.0100909
IFIT3 interferon-induced protein with tetratricopeptide repeats 3 0.010006
GOLGA8A golgin A8 family, member A 0.0100008
ABLIM1 actin binding LIM protein 1 0.0099772
ATF3 activating transcription factor 3 0.00995799
CSTA cystatin A (stefin A) 0.0097723
LXN latexin 0.00974664
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein 0.00974432
MVP major vault protein 0.00973153
CARMIL1 capping protein regulator and myosin 1 linker 1 0.00967638
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1 0.00960166
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.0095619
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 0.00954303
EGR2 early growth response 2 0.00946801
SPRR3 small proline-rich protein 3 0.0093985
TYMP thymidine phosphorylase 0.00931762
ISG15 ISG15 ubiquitin-like modifier 0.00930245
FOLR1 folate receptor 1 (adult) 0.00929994
IFI27 interferon, alpha-inducible protein 27 0.0092972
ZYX zyxin 0.00927277
TM4SF1 transmembrane 4 L six family member 1 0.00924805
HSPA6 heat shock 70kDa protein 6 (HSP70B') 0.00922836
FAIM Fas apoptotic inhibitory molecule 0.00918302
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) 0.00899402
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 0.00897278
IER5 immediate early response 5 0.00883687
LGALS13 lectin, galactoside-binding, soluble, 13 0.00882834
SCGB2A1 secretoglobin, family 2A, member 1 0.00878221
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 0.00871868
BST2 bone marrow stromal cell antigen 2 0.00867188
PRSS21 protease, serine, 21 (testisin) 0.00861166
EVI2A ecotropic viral integration site 2A 0.00859298
LUM lumican 0.00856221
TFRC transferrin receptor 0.00852043
NCF2 neutrophil cytosolic factor 2 0.00848561
MYOF myoferlin 0.00844389
FOSB FBJ murine osteosarcoma viral oncogene homolog B 0.00844182
VLDLR very low density lipoprotein receptor 0.00843321
SFRP1 secreted frizzled-related protein 1 0.0083725
TEX10 testis expressed 10 0.00835766
SORT1 sortilin 1 0.00828511
RABAC1 Rab acceptor 1 (prenylated) 0.00827
SCARB2 scavenger receptor class B, member 2 0.00825123
TNNC1 troponin C type 1 (slow) 0.00818648
FABP4 fatty acid binding protein 4, adipocyte 0.00815526
EIF5 eukaryotic translation initiation factor 5 0.00815405
OXTR oxytocin receptor 0.00813225
PODXL podocalyxin-like 0.00804033
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated) 0.00802674
RSL1D1 ribosomal L1 domain containing 1 0.00797339
GAS1 growth arrest-specific 1 0.00795378
PDZK1IP1 PDZK1 interacting protein 1 0.00792132
IER2 immediate early response 2 0.00788172
TENT5A terminal nucleotidyltransferase 5A 0.00786003
RTN2 reticulon 2 0.0078443
MAP1LC3B microtubule-associated protein 1 light chain 3 beta 0.00782769
MB myoglobin 0.00779374
MNDA myeloid cell nuclear differentiation antigen 0.00778239
PLIN3 perilipin 3 0.007659
TPM4 tropomyosin 4 0.00763568
TMEM45A transmembrane protein 45A 0.00761503
ASNS asparagine synthetase (glutamine-hydrolyzing) 0.00755231
MPO myeloperoxidase 0.00753838
TAGLN transgelin 0.00753176
VAMP8 vesicle-associated membrane protein 8 0.00752943
FABP5 fatty acid binding protein 5 (psoriasis-associated) 0.00750625
HOMER1 homer scaffolding protein 1 0.00750301
ATP6V0E1 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1 0.00749242
KYNU kynureninase 0.00745689
MAGEA3 melanoma antigen family A3 0.00741724
PPA1 pyrophosphatase (inorganic) 1 0.00740164
ELF1 E74-like factor 1 (ets domain transcription factor) 0.00739371
TACSTD2 tumor-associated calcium signal transducer 2 0.00735818
SLC38A2 solute carrier family 38, member 2 0.00734741
RPS27L ribosomal protein S27-like 0.00727595
ETHE1 ethylmalonic encephalopathy 1 0.00724468
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD) 0.00722923
COL10A1 collagen, type X, alpha 1 0.00720858
FZD6 frizzled class receptor 6 0.00720618
TARP TCR gamma alternate reading frame protein 0.00720377
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 0.00719893
PLK2 polo-like kinase 2 0.00718288
YPEL5 yippee-like 5 (Drosophila) 0.00712758
FCN1 ficolin (collagen/fibrinogen domain containing) 1 0.00712624
TRIM16 tripartite motif containing 16 0.0070355
DCN decorin 0.00702271
MT1X metallothionein 1X 0.00700388
CTSG cathepsin G 0.00699645
PI3 peptidase inhibitor 3, skin-derived 0.00698427
LOX lysyl oxidase 0.00697627
STC2 stanniocalcin 2 0.00694867
ZKSCAN1 zinc finger with KRAB and SCAN domains 1 0.00688186
GABRP gamma-aminobutyric acid (GABA) A receptor, pi 0.00686931
LAMP3 lysosomal-associated membrane protein 3 0.00685881
F2RL1 coagulation factor II (thrombin) receptor-like 1 0.00685475
UBFD1 ubiquitin family domain containing 1 0.00684138
MID1IP1 MID1 interacting protein 1 0.00683598
MMP11 matrix metallopeptidase 11 0.00683404
CRABP2 cellular retinoic acid binding protein 2 0.00681429
WWC1 WW and C2 domain containing 1 0.00680272
FGF9 fibroblast growth factor 9 0.00678024
DHX32 DEAH (Asp-Glu-Ala-His) box polypeptide 32 0.00675657
CTTN cortactin 0.00672865
PPP1R15A protein phosphatase 1, regulatory subunit 15A 0.00671038
BEX4 brain expressed, X-linked 4 0.00670855
IL17RA interleukin 17 receptor A 0.00670471
GCH1 GTP cyclohydrolase 1 0.00664372
DHRS2 dehydrogenase/reductase (SDR family) member 2 0.00663939
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 0.00663038
HACD1 3-hydroxyacyl-CoA dehydratase 1 0.00662304
RGS10 regulator of G-protein signaling 10 0.00660861
HSPE1 heat shock 10kDa protein 1 0.00660096
RBMS1 RNA binding motif, single stranded interacting protein 1 0.00659473
MUC16 mucin 16, cell surface associated 0.00657759
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 0.00655655
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta 0.00654517
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C 0.00653834
CD36 CD36 molecule (thrombospondin receptor) 0.0065321
ADO 2-aminoethanethiol (cysteamine) dioxygenase 0.00652775
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 0.00652755
SLC6A14 solute carrier family 6 (amino acid transporter), member 14 0.00652316
SH3YL1 SH3 and SYLF domain containing 1 0.0065133
SLC31A2 solute carrier family 31 (copper transporter), member 2 0.00647879
CFD complement factor D (adipsin) 0.00647412
CCDC6 coiled-coil domain containing 6 0.00645654
TNIP1 TNFAIP3 interacting protein 1 0.0064415
KRT18 keratin 18, type I 0.00643406
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 0.00643323
POLDIP2 polymerase (DNA-directed), delta interacting protein 2 0.00643083
HK2 hexokinase 2 0.00642007
RASSF2 Ras association (RalGDS/AF-6) domain family member 2 0.00641341
CCNA2 cyclin A2 0.00639824
GATA6 GATA binding protein 6 0.00639594
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.0063782
CYB5R1 cytochrome b5 reductase 1 0.00637518
PLPP2 phospholipid phosphatase 2 0.00635333
FXYD3 FXYD domain containing ion transport regulator 3 0.00634464
TP53I3 tumor protein p53 inducible protein 3 0.00633136
ANXA2P2 annexin A2 pseudogene 2 0.00630421
HCK HCK proto-oncogene, Src family tyrosine kinase 0.00629299
CARHSP1 calcium regulated heat stable protein 1, 24kDa 0.00628904
IFI30 interferon, gamma-inducible protein 30 0.00628117
AIM2 absent in melanoma 2 0.00627875
NRBF2 nuclear receptor binding factor 2 0.00627859
CA2 carbonic anhydrase II 0.00627733
EEF1A2 eukaryotic translation elongation factor 1 alpha 2 0.0062754
FSTL3 follistatin-like 3 (secreted glycoprotein) 0.00626807
NLRP2 NLR family, pyrin domain containing 2 0.00623452
CRYAB crystallin, alpha B 0.00621295
HSPD1 heat shock 60kDa protein 1 (chaperonin) 0.0062108
IFITM1 interferon induced transmembrane protein 1 0.00618213
MOAP1 modulator of apoptosis 1 0.00615554
EIF5A eukaryotic translation initiation factor 5A 0.00615116
MT1F metallothionein 1F 0.00615067
HOMER3 homer scaffolding protein 3 0.00614886
PADI2 peptidyl arginine deiminase, type II 0.00614526
GDE1 glycerophosphodiester phosphodiesterase 1 0.00613863
ISG20 interferon stimulated exonuclease gene 20kDa 0.00613822
ATP6V1C1 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 0.0061344
MYO1C myosin IC 0.0060949
CXCL13 chemokine (C-X-C motif) ligand 13 0.00607879
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5 0.00606858
OASL 2'-5'-oligoadenylate synthetase-like 0.00605023
PHF11 PHD finger protein 11 0.00604769
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1 0.0060463
ZFAND5 zinc finger, AN1-type domain 5 0.00603194
HIST1H2BD histone cluster 1, H2bd 0.00602227
CALB1 calbindin 1, 28kDa 0.00601186
CRISP3 cysteine-rich secretory protein 3 0.00598645
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6 0.00597032
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3 0.0059697
SAT1 spermidine/spermine N1-acetyltransferase 1 0.00595949
C21ORF91 chromosome 21 open reading frame 91 0.00595812
CYTIP cytohesin 1 interacting protein 0.00594088
MT2A metallothionein 2A 0.00592629
HECA headcase homolog (Drosophila) 0.00592444
HIST1H2AC histone cluster 1, H2ac 0.00591923
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa 0.0059096
ZNF665 zinc finger protein 665 0.00590367
THBS1 thrombospondin 1 0.00590302
MSL1 male-specific lethal 1 homolog (Drosophila) 0.00590302
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 0.00588614
WARS1 tryptophanyl-tRNA synthetase 1 0.00588233
COL11A1 collagen, type XI, alpha 1 0.0058722
JUNB jun B proto-oncogene 0.00586959
MRPL33 mitochondrial ribosomal protein L33 0.0058678
TPD52L1 tumor protein D52-like 1 0.00586307
CCNG1 cyclin G1 0.00583798
BCL2A1 BCL2-related protein A1 0.00582895
CD53 CD53 molecule 0.00579463
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 0.00578232
TSC22D2 TSC22 domain family, member 2 0.00577494
SELL selectin L 0.00577262
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 0.00577044
CHMP1B charged multivesicular body protein 1B 0.00576236
NT5C2 5'-nucleotidase, cytosolic II 0.00575805
CRABP1 cellular retinoic acid binding protein 1 0.005752
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12 0.00572675
FAM198B family with sequence similarity 198, member B 0.00572263
NDUFAB1 NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8kDa 0.00572053
GREM1 gremlin 1, DAN family BMP antagonist 0.00571235
RAB9A RAB9A, member RAS oncogene family 0.00570705
GOLM1 golgi membrane protein 1 0.00570348
CRK v-crk avian sarcoma virus CT10 oncogene homolog 0.00569847
NCOA3 nuclear receptor coactivator 3 0.00568378
SCAF11 SR-related CTD-associated factor 11 0.00568066
ZDHHC24 zinc finger, DHHC-type containing 24 0.00567232
FAM102A family with sequence similarity 102, member A 0.0056667
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) 0.0056549
IFI6 interferon, alpha-inducible protein 6 0.00564642
SOX11 SRY (sex determining region Y)-box 11 0.00563716
KRT81 keratin 81, type II 0.00563401
CLDN7 claudin 7 0.0056275
PPID peptidylprolyl isomerase D 0.00561742
PNMA1 paraneoplastic Ma antigen 1 0.00561624
APOBEC3A apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A 0.00561293
IL1RN interleukin 1 receptor antagonist 0.00561229
PRSS8 protease, serine, 8 0.00560978
MED6 mediator complex subunit 6 0.00560438
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A 0.00560389
NPIPB3 nuclear pore complex interacting protein family, member B3 0.00559665

decreased expression

Symbol Name Standardized Value
SPRED2 sprouty-related, EVH1 domain containing 2 -0.0251602
RGS5 regulator of G-protein signaling 5 -0.0144525
IGFBP5 insulin-like growth factor binding protein 5 -0.0140837
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -0.013645
FGFR3 fibroblast growth factor receptor 3 -0.0136361
BMP4 bone morphogenetic protein 4 -0.0130435
PCP4 Purkinje cell protein 4 -0.0127028
TXLNA taxilin alpha -0.012685
A2M alpha-2-macroglobulin -0.012547
MAOA monoamine oxidase A -0.0123082
COPS7A COP9 signalosome subunit 7A -0.0122853
RPS4Y1 ribosomal protein S4, Y-linked 1 -0.0116675
ACAT2 acetyl-CoA acetyltransferase 2 -0.0114147
PSMD4 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 -0.0108824
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) -0.0103866
SFTPB surfactant protein B -0.0103449
RAPSN receptor-associated protein of the synapse -0.0103175
BCHE butyrylcholinesterase -0.0101818
CCND2 cyclin D2 -0.0100947
CDC20 cell division cycle 20 -0.0100372
FCGBP Fc fragment of IgG binding protein -0.00996055
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 -0.00991808
KANK2 KN motif and ankyrin repeat domains 2 -0.00991433
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 -0.00986572
SLIT2 slit homolog 2 (Drosophila) -0.00976245
EPS8 epidermal growth factor receptor pathway substrate 8 -0.00974414
SMTN smoothelin -0.00959305
CXCL14 chemokine (C-X-C motif) ligand 14 -0.00955334
OLFM4 olfactomedin 4 -0.00948213
PPAP2A phosphatidic acid phosphatase type 2A -0.00910459
MFHAS1 malignant fibrous histiocytoma amplified sequence 1 -0.00909757
XPO7 exportin 7 -0.0090939
TSPAN7 tetraspanin 7 -0.00901082
CD9 CD9 molecule -0.00899108
CIT citron rho-interacting serine/threonine kinase -0.00898021
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila) -0.00892367
ZBTB18 zinc finger and BTB domain containing 18 -0.00891528
SFTPA2 surfactant protein A2 -0.00888712
RCAN2 regulator of calcineurin 2 -0.00879594
ENPP4 ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative) -0.00876518
ANPEP alanyl (membrane) aminopeptidase -0.00871789
LRP4 low density lipoprotein receptor-related protein 4 -0.00871714
SDC2 syndecan 2 -0.00859137
GPX3 glutathione peroxidase 3 -0.00851515
SEPP1 selenoprotein P, plasma, 1 -0.00849614
TGFBI transforming growth factor, beta-induced, 68kDa -0.00846454
SPARCL1 SPARC-like 1 (hevin) -0.00844232
PLN phospholamban -0.00840754
HMGB1 high mobility group box 1 -0.00817794
PER2 period circadian clock 2 -0.00813191
FASN fatty acid synthase -0.00812606
CD320 CD320 molecule -0.00810788
AQP1 aquaporin 1 (Colton blood group) -0.00804742
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1 -0.00803272
MYH11 myosin, heavy chain 11, smooth muscle -0.00799442
METTL7A methyltransferase like 7A -0.00786666
SPARC secreted protein, acidic, cysteine-rich (osteonectin) -0.00786417
DEGS1 delta(4)-desaturase, sphingolipid 1 -0.00781013
LAMC1 laminin, gamma 1 (formerly LAMB2) -0.00779297
THY1 Thy-1 cell surface antigen -0.00774075
COLEC12 collectin sub-family member 12 -0.00773644
CNPY3 canopy FGF signaling regulator 3 -0.00773619
NAV2 neuron navigator 2 -0.00772638
H1-0 H1.0 linker histone -0.00763417
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen) -0.00751771
PCCA propionyl CoA carboxylase, alpha polypeptide -0.00734505
FBLN2 fibulin 2 -0.00734463
CHKB choline kinase beta -0.00733993
PLPP3 phospholipid phosphatase 3 -0.00733211
AGR2 anterior gradient 2 -0.00732757
OLFM1 olfactomedin 1 -0.00725721
VCAM1 vascular cell adhesion molecule 1 -0.00719768
RBPMS RNA binding protein with multiple splicing -0.00718846
ZNF423 zinc finger protein 423 -0.00716115
SPRY2 sprouty homolog 2 (Drosophila) -0.00714084
SCRG1 stimulator of chondrogenesis 1 -0.00708489
GPSM2 G-protein signaling modulator 2 -0.00704715
FBXO11 F-box protein 11 -0.00701366
PRUNE2 prune homolog 2 (Drosophila) -0.006994
PDZRN4 PDZ domain containing ring finger 4 -0.00698145
CTSK cathepsin K -0.00697381
ARHGEF10 Rho guanine nucleotide exchange factor (GEF) 10 -0.00696983
FABP1 fatty acid binding protein 1, liver -0.00696982
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) -0.00696413
TNS1 tensin 1 -0.00693542
DCXR dicarbonyl/L-xylulose reductase -0.00686933
PSD3 pleckstrin and Sec7 domain containing 3 -0.00682916
ADIRF adipogenesis regulatory factor -0.0068285
TNC tenascin C -0.0068102
ADGRF5 adhesion G protein-coupled receptor F5 -0.00680093
RXRA retinoid X receptor, alpha -0.00679227
CCNF cyclin F -0.00678645
DDAH1 dimethylarginine dimethylaminohydrolase 1 -0.0067386
TIMP3 TIMP metallopeptidase inhibitor 3 -0.00671028
PRKD3 protein kinase D3 -0.00668667
PTP4A2 protein tyrosine phosphatase type IVA, member 2 -0.0066826
TMEM176B transmembrane protein 176B -0.00664009
CDH1 cadherin 1, type 1, E-cadherin (epithelial) -0.00661047
CP ceruloplasmin (ferroxidase) -0.00659857
FADS1 fatty acid desaturase 1 -0.00659854
ABCD3 ATP-binding cassette, sub-family D (ALD), member 3 -0.00659425
IGFBP1 insulin-like growth factor binding protein 1 -0.0065813
TMEM38B transmembrane protein 38B -0.00656256
SPRY4 sprouty homolog 4 (Drosophila) -0.00653101
MCM5 minichromosome maintenance complex component 5 -0.00649802
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1 -0.00649796
CD302 CD302 molecule -0.0064796
ITM2C integral membrane protein 2C -0.00646508
HDAC1 histone deacetylase 1 -0.00645856
GCLC glutamate-cysteine ligase, catalytic subunit -0.0064492
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 -0.00642269
PCOLCE2 procollagen C-endopeptidase enhancer 2 -0.00641998
ITGB4 integrin, beta 4 -0.00638039
APLNR apelin receptor -0.00635503
NEIL3 nei endonuclease VIII-like 3 (E. coli) -0.0063467
SLC29A1 solute carrier family 29 (equilibrative nucleoside transporter), member 1 -0.00634241
FANCL Fanconi anemia, complementation group L -0.00634015
PRKDC protein kinase, DNA-activated, catalytic polypeptide -0.00629827
FERMT1 fermitin family member 1 -0.00629367
RAB40B RAB40B, member RAS oncogene family -0.00625728
TPSAB1 tryptase alpha/beta 1 -0.00625723
LAMA4 laminin, alpha 4 -0.00625658
TNS3 tensin 3 -0.00625085
NDC80 NDC80 kinetochore complex component -0.00624065
PRKCA protein kinase C, alpha -0.00623544
SNX1 sorting nexin 1 -0.00619686
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 -0.0061785
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 -0.00616216
KIF18B kinesin family member 18B -0.00615454
PTCH1 patched 1 -0.00615105
BAD BCL2-associated agonist of cell death -0.00614353
NSD2 nuclear receptor binding SET domain protein 2 -0.00613552
ALDH1L1 aldehyde dehydrogenase 1 family, member L1 -0.00611515
SHOX2 short stature homeobox 2 -0.00609618
SLC6A1 solute carrier family 6 (neurotransmitter transporter), member 1 -0.00608309
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1 -0.00607704
TGFB1I1 transforming growth factor beta 1 induced transcript 1 -0.00607497
LGR5 leucine-rich repeat containing G protein-coupled receptor 5 -0.00602941
AOC1 amine oxidase, copper containing 1 -0.00601612
TMEM255A transmembrane protein 255A -0.0060058
PEX5 peroxisomal biogenesis factor 5 -0.00599427
CTDSPL CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like -0.0059741
LBR lamin B receptor -0.00597388
SUSD5 sushi domain containing 5 -0.00592529
AGTR1 angiotensin II receptor, type 1 -0.00591214
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase -0.00587784
ITGB3BP integrin beta 3 binding protein (beta3-endonexin) -0.00587134
GNAL guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type -0.00586912
PTP4A3 protein tyrosine phosphatase type IVA, member 3 -0.00585657
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) -0.00585097
DPP6 dipeptidyl-peptidase 6 -0.00582193
GPR88 G protein-coupled receptor 88 -0.00581895
ISL1 ISL LIM homeobox 1 -0.00581244
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1) -0.00580105
ASCL1 achaete-scute family bHLH transcription factor 1 -0.00579043
TRMT5 tRNA methyltransferase 5 -0.00577373
PLEKHA5 pleckstrin homology domain containing, family A member 5 -0.00577028
BEX1 brain expressed, X-linked 1 -0.00576851
FBXO5 F-box protein 5 -0.00576213
FOXF1 forkhead box F1 -0.00576064
CLCA1 chloride channel accessory 1 -0.00575821
MATN2 matrilin 2 -0.00574456
PER3 period circadian clock 3 -0.0057333
RAMP1 receptor (G protein-coupled) activity modifying protein 1 -0.00573104
PDLIM4 PDZ and LIM domain 4 -0.00572951
SYNM synemin, intermediate filament protein -0.00571714
KCTD9 potassium channel tetramerization domain containing 9 -0.00571576
CYP4F3 cytochrome P450, family 4, subfamily F, polypeptide 3 -0.0056946
FDPS farnesyl diphosphate synthase -0.00565472
TBL1X transducin (beta)-like 1X-linked -0.00565349
LGALS4 lectin, galactoside-binding, soluble, 4 -0.00565127
HOXC10 homeobox C10 -0.00564444
FBXO3 F-box protein 3 -0.00563442
REG1A regenerating islet-derived 1 alpha -0.0056341
ZBTB16 zinc finger and BTB domain containing 16 -0.00563379
FOXM1 forkhead box M1 -0.00560713
DPM3 dolichyl-phosphate mannosyltransferase polypeptide 3 -0.00560701
APLP2 amyloid beta (A4) precursor-like protein 2 -0.00560118
RTN1 reticulon 1 -0.00559154
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3 -0.00557757
C1R complement component 1, r subcomponent -0.00557161
ITGA6 integrin, alpha 6 -0.00556688
HS3ST1 heparan sulfate (glucosamine) 3-O-sulfotransferase 1 -0.00553171
MDC1 mediator of DNA-damage checkpoint 1 -0.0055279
SRC SRC proto-oncogene, non-receptor tyrosine kinase -0.00551706
CBX5 chromobox homolog 5 -0.00547056
POLD2 polymerase (DNA directed), delta 2, accessory subunit -0.00546696
RASL12 RAS-like, family 12 -0.00545897
PTPRD protein tyrosine phosphatase, receptor type, D -0.0054445
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 -0.00543625
FHL1 four and a half LIM domains 1 -0.00543503
CYP39A1 cytochrome P450, family 39, subfamily A, polypeptide 1 -0.0054345
OGFOD3 2-oxoglutarate and iron-dependent oxygenase domain containing 3 -0.00542056
PTGFR prostaglandin F receptor (FP) -0.0054159
ANP32E acidic (leucine-rich) nuclear phosphoprotein 32 family, member E -0.0054156
STK26 serine/threonine protein kinase 26 -0.00540287
GAL galanin/GMAP prepropeptide -0.00539708
ATP11B ATPase, class VI, type 11B -0.00539154
DDX39A DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A -0.00538265
ADAMTSL3 ADAMTS-like 3 -0.00538082
INTS1 integrator complex subunit 1 -0.00537986
WFS1 Wolfram syndrome 1 (wolframin) -0.00537441
ARHGEF9 Cdc42 guanine nucleotide exchange factor (GEF) 9 -0.00537261
AMT aminomethyltransferase -0.00536665
HOPX HOP homeobox -0.00536659
KDM5D lysine (K)-specific demethylase 5D -0.00536092
RNASE1 ribonuclease, RNase A family, 1 (pancreatic) -0.00536051
MGP matrix Gla protein -0.00535903
SDC3 syndecan 3 -0.00533853
NEK2 NIMA-related kinase 2 -0.00532732
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1 -0.00532428
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 -0.0053218
PSMD13 proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 -0.00531364
COL1A2 collagen, type I, alpha 2 -0.00530668
SRPRA SRP receptor subunit alpha -0.00528733
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit -0.00528711
ECI2 enoyl-CoA delta isomerase 2 -0.00528588
NELL1 NEL-like 1 (chicken) -0.00528507
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3 -0.005283
FGFR1 fibroblast growth factor receptor 1 -0.00528201
EPHX2 epoxide hydrolase 2, cytoplasmic -0.00528174
TMEM106C transmembrane protein 106C -0.00527339
ZNF274 zinc finger protein 274 -0.00526643
PLAT plasminogen activator, tissue -0.00526134
FXYD2 FXYD domain containing ion transport regulator 2 -0.00525719
KAT2B K(lysine) acetyltransferase 2B -0.00525509
TTC38 tetratricopeptide repeat domain 38 -0.00525353
TIMP4 TIMP metallopeptidase inhibitor 4 -0.00524696
KIF1A kinesin family member 1A -0.00524136
DKFZP586I1420 uncharacterized protein DKFZp586I1420 -0.00522946
MAOB monoamine oxidase B -0.00522936
ARG1 arginase 1 -0.00522876
FBXL7 F-box and leucine-rich repeat protein 7 -0.00522615
ZSCAN18 zinc finger and SCAN domain containing 18 -0.00522427
DVL1 dishevelled segment polarity protein 1 -0.00522359
ADGRL3 adhesion G protein-coupled receptor L3 -0.00521943
GLO1 glyoxalase I -0.00521837
RRBP1 ribosome binding protein 1 -0.00519181
ITIH1 inter-alpha-trypsin inhibitor heavy chain 1 -0.0051914
SERPINF2 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 -0.00518304
ARG2 arginase 2 -0.00517155
NR3C2 nuclear receptor subfamily 3, group C, member 2 -0.00517059
FXYD6 FXYD domain containing ion transport regulator 6 -0.00515819
RNF43 ring finger protein 43 -0.0051517
FAM149A family with sequence similarity 149, member A -0.00515101
SLC23A2 solute carrier family 23 (ascorbic acid transporter), member 2 -0.00514666
GNG12 guanine nucleotide binding protein (G protein), gamma 12 -0.00514407
PRRX1 paired related homeobox 1 -0.00513722
NBL1 neuroblastoma 1, DAN family BMP antagonist -0.00513089